Imajin se pɔsin we yu sabi gud gud wan ɛn we bin dɔn gɛt wɛlbɔdi trade, kin bigin fɔ biev smɔl strenj wantɛm wantɛm. Dɛn nɔ kin mɛmba tin igen, i nɔ kin izi fɔ dɛn fɔ waka , ɛn dɛn kin tɔk bad bɔt dɛn wɔd dɛn we dɛn de tɔk. If dɛn tin ya kin apin pan wan rit we yu nɔ go ebul fɔ imajin fɔ sɔm mɔnt, i kin bi bikɔs ɔf wan sik we nɔ kin apin na di bren we nɔ kin apin so ɔltɛm bɔt we rili siriɔs. Tide wi de tɔk bɔt wan pan dɛn kayn sik ya, we na Creutzfeldt-Jakob Disease, ɔ CJD lɛk aw wi ɔl kin kɔl am. Pan ɔl we dis na tɔpik we de mek pɔsin fred smɔl, i rili impɔtant fɔ mek yu no bɔt am gud gud wan.
CJD en "mad cow disease" na di sem tin?
Bɔku pipul dɛn kin kɔnfyus CJD wit "Mad Cow Disease." Bɔt, dɛn tu tin ya nɔto di sem.
Fɔ tɔk am simpul wan, Bovine Spongiform Encephalopathy (BSE) na wan sik we de ambɔg di bren we kin jɔs afɛkt kaw. We i apin, di kaw dɛn nervɔs sistɛm kin pwɛl, we kin mek dɛn nɔ ebul fɔ muv ɛn biev strenj.
Bɔt wan kayn CJD de we mɔtalman kin gɛt we i it di mit fɔ kaw we gɛt mad kaw sik . Dɛn kɔl am Variant CJD (vCJD) . Bɔt dis kin rili, rili rare . Na smɔl pipul dɛn nɔmɔ dɛn dɔn ripɔt ɔlsay na di wɔl. So dis nɔto aw di CJD sik we wi kin tɔk bɔt kin apin.
Wetin mek dis CJD sik kin apin?
di men tin we kin mek wi gɛt CJD na we wan prɔtin we de na wi bɔdi nɔ kin chenj. Dɛn kɔl dis prɔtin we nɔmal ɛn we dɔn chenj, priɔn .
Tink bɔt wan wɛlbɔdi prɔtin na wi bren lɛk pepa we dɛn fold fayn fayn wan. dis mutant protin we dεn kכl prion de kam εn fold dis gud pepa kכrekt wan. Dɔn da pepa de we dɛn nɔ fold fayn kin go bifo fɔ fold di ɔda gud pepa dɛn di rɔŋ we. Ɛn so, di bren sɛl dɛn kin pwɛl smɔl smɔl. If yu luk am ɔnda maykroskɔp, dis bren tisu we dɔn pwɛl go tan lɛk spɔnj.
Tri kayn CJD de dipכnt pan aw di prion de fכm.
| Tayp fɔ di CJD | Rizin ɛn ɛksplen |
|---|---|
| Sporadik CJD we de apin | Dis na di kayn we we pipul dɛn kin gɛt mɔ. Fɔ no rizin, wan wɛlbɔdi prɔtin kin chenj wantɛm wantɛm ɛn tɔn to priɔn. Mɔs pan di wan dɛn we gɛt CJD gɛt dis kayn. |
| Famili CJD we de na di famili | Dis kin apin bikɔs ɔf wan prɔblɛm we de na in jɛnɛtiks. If wan pan di mama ɛn papa gɛt wan jin we dɔn chenj we de mek dis sik, i kin pas to di pikin dɛn. Bɔt dis kin rili rare bak. Na lɛk 10%-15% pan di wan dɛn we gɛt CJD kin fɔdɔm insay dis kategori. |
| Akwyayz CJD | Dis na di kayn we we nɔ bɔku. Pɔsin kin gɛt CJD tru kɔntaminɛt mɛdikal ikwipmɛnt (e.g. we dɛn de du ɔpreshɔn), wan ɔgan transplant, ɔ kɔntaminɛt growth ɔmon injɛkshɔn. Dis risk dɔn ridyus bad bad wan bikɔs ɔf di strikt sef we dɛn de du na ɔspitul tide. |
Wetin na di sayn dɛm fɔ CJD?
De tin wae denja pasmak bɔt CJD na wae de sik kin bigin kwik kwik wan ɛn wɔs kwik kwik wan. Bɔrku tɛm, dɛn sayn ya kin tan lɛk de sik wae de mɛk pɔrsin gɛt dis maynia sik.
Di men tin dɛn we pɔsin kin si na:
- Di mɛmori lɔs ɛn kɔnfyushɔn
- I nɔ kin izi fɔ waka ɛn i nɔ kin balans igen
- Di mɔsul dɛn kin twitch wantɛm wantɛm (jɛk muvmɛnt) .
- Pɔsin kin chenj (we kin vɛks wantɛm wantɛm, i kin vɛks) .
- I nɔ kin izi fɔ tink ɛn disayd fɔ du sɔntin
- Prɔblɛm dɛn we pɔsin kin gɛt we i de si
- Nɔr kin slip ɛn pwɛl hat
Difrɛns bitwin CJD ɛn Alzaima sik
Dɛn sayn ya kin mɛmba yu bɔt Alzaima sik. Bɔt di men difrɛns na di spid we i de spid . Insay Alzaima sik, tin lɛk fɔ mɛmba tin kin apin smɔl smɔl fɔ lɔng tɛm. Bɔt pan CJD, di sikman in kɔndishɔn kin wɔs kwik kwik wan, insay sɔm wik ɔ mɔnt frɔm we dɛn sik ya bigin.
Aw fɔ no dis sik kɔrɛkt wan?
I sɔri fɔ no se, no wan tɛst nɔ de we go ebul fɔ kɔnfɔm CJD. Dɔktɔ dɛn kin mek di diagnosis bay di sikman in sayn dɛm ɛn aw dɛn kin bigin fɔ gɛt am kwik kwik wan. Bɔt if dɛn tink se di sik de, dɛn kin du bɔku tɛst fɔ no if i gɛt am.
- MRI (Magnetic Resonance Imaging) scan: Dis kin tek ditayli pikchɔ dɛn bɔt di bren. I kin luk fɔ sɔm patikyula chenj dɛn na di bren we kin apin na CJD.
- EEG (Electroencephalogram) test: Dis tεst de mכsu di ilektrikal aktiviti fכ di bren bay we dεn de yuz sכm sכm sכm sεns dεm we de atak di sכl. Dis tεst kin sho patεn dεm we de kכntribyut to CJD pasεnshכn dεm.
- di lכmba pankchכ: we dεn de yuz wan rili fayn nidul, dεn de tek sכm sכm sכm sεribrospεnal fכluid frכm insay di spεnal kכd εn tεst fכ spεsifi k protin dεm we dεn si na CJD.
di onli we fכ kכnfכm dis sik wit 100% sכri na fכ tek bren tisu sεmpl (bayopsi). Bɔt fɔ tek dis kayn sɛmpul frɔm pɔsin we de alayv in bren kin rili risky fɔ di pɔsin ɛn di dɔktɔ, so bɔku tɛm dɛn nɔ kin du am. Bɔrku tɛm, dɛn kin kɔnfirm di sik fɔ tru afta di pɔsin dɔn day.
Aw de sik kin wɔs as tɛm de go
CJD kin go bifo tru sɔm stej dɛm as tɛm de go, we kin mek i rili pen fɔ di pɔsin ɛn dɛn famili.
| Stej we di sik de | Di tin dɛn we dɛn de ɛkspɛkt |
|---|---|
| Di fɔs stej | Fɔ tɔk smɔl smɔl we yu de tɔk, fɔ gɛt diziz, fɔ mek yu nɔ fil fayn na yu bɔdi, fɔ si tin dɛn we nɔ de (hallucinations), fɔ vɛks fɔ natin, fɔ pul yusɛf kɔmɔt na di sosayti, ɛn fɔ nɔ ebul fɔ slip. |
| Leta stej | Nɔ ebul fɔ kɔntrol di bɔdi ɛn blad, i nɔ kin izi fɔ swɛla ɛn tɔk, i kin rili mɛmori, i kin gɛt paranoia, i kin de na bed, i kin gɛt kɔma. |
Na lɛk 70% pan di pipul dɛm wae gɛt CJD kin day afta dɛn dɔn no bɔt dɛn sik.Yu go day insay wan ia. We yu yɛri dis, yu kin fil bad bad wan, yu at kin fil bad, ɛn yu kin vɛks. Dis na tin we rili nɔmal. Nɔ sɔfa yu wan na tɛm lɛk dis. I rili impɔtant fɔ tɔk to yu dɔktɔ ɛn gɛt di saykolojik sɔpɔt we yu nid.
Tritmɛnt de fɔ CJD?
Bɔt i sɔri fɔ no se, dɛn stil nɔ gɛt ɛni mɛrɛsin ɔ tritmɛnt fɔ CJD. Risach pipul dɛn dɔn tray bɔku mɛrɛsin dɛn, bɔt nɔbɔdi nɔ ebul fɔ tek am.
Di wangren tin we dɛn kin du rayt naw na fɔ kɔntrol di sik dɛn . Dat min se:
- Gi pen kil fɔ pen.
- Gi mɛrɛsin fɔ mek di mɔsul dɛn stif ɛn fɔ mek yu gɛt spasm.
- Fɔ gi di pɔsin di tin dɛn we i nid fɔ mek i fil fayn as i pɔsibul.
Wae de sik dɔn kam tranga, de pɔrsin go nid fɔ kia fɔ am ɔltɛm. Risach de go bifo fɔ fɛn tritmɛnt fɔ dis sik tumara bambay. If yu intres, yu kin aks yu dɔktɔ bɔt klinik trial dɛm we de tɛst nyu tritmɛnt dɛm.
Mɛsej we dɛn kin kɛr go na os
- Creutzfeldt-Jakob Disease (CJD) na wan sik we nɔ kin bɔku ɛn we kin prɛd kwik kwik wan we kin kil pɔsin na in bren.
- Dis kin apin bikɔs ɔf wan prɔtin we dɔn chenj we dɛn kɔl prion we de pwɛl di bren sɛl dɛn.
- CJD ɛn "Mad Cow Disease" na tu difrɛn sik dɛm. Bɔt wan kayn CJD (vCJD) de we nɔ kin bɔku we pɔsin kin gɛt we i it bif we gɛt di sik.
- Nɔr mɛrɛsin nɔr de fɔ dis sik yet. Ɔl wetin dɛn kin du na fɔ kɔntrol di sik dɛn ɛn mek di pɔsin fil fayn.
- If pɔsin we yu sabi gɛt bɔku chenj dɛn na in mɛmori, in bihayvya, ɛn in bɔdi wok insay shɔt tɛm, go to dɔktɔ wantɛm wantɛm . I impɔtant fɔ no di sik kwik kwik wan fɔ mek dɛn plan ɛn kia fɔ am fayn fayn wan.
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