Sɔntɛnde, yu kin fil taya ɔ yu kin taya fɔ natin? Yu skin de luk yɔlɔ? Ɔ yu nyu bɔn pikin in janda nɔ kin dɔn afta tu wiks? di tin we kin mek dεn tin ya kin bi we yu nכ gεt wan εnzym we dεn kכl G6PD na yu bכdi. Nɔr wɔri, dis na wan sik wae kin pasmak. Tide, wi go tɔk simpul ɛn klia wan bɔt wetin na G6PD, wetin kin apin we i smɔl, ɛn di G6PD tɛst.
Wetin na G6PD simpul wan?
Tink bɔt di rɛd blɔd sɛl dɛn we de na wi bɔdi lɛk sojaman dɛn we de wok. Wan ‘gad’ de we de protɛkt dɛn sojaman ya frɔm difrɛn bad tin dɛn. Dat gad na wan ɛnzaym we dɛn kɔl G6PD.
Fɔ tɔk am simpul wan, G6PD (Glucose-6-Phosphate Dehydrogenase) na wan rili impɔtant ɛnzaym we de protɛkt wi sɛl dɛn, mɔ di rɛd blɔd sɛl dɛn na wi blɔd, frɔm kemikal dɛn we de ambɔg wi. wi bכdi de mek tin dεm we de du bad (dεn kכl dεm bak ‘Free Radikal’ כ ‘Reactive Oxygen Species’ ) we de mek we i de wok nכmal. di G6PD εnzym de du dis bay we i de mek dεn bad bad tin ya nכ de kכmכt εn damej di sεl dεm.
Wetin kin apin we G6PD smɔl?
Naw imajin wetin go apin if da ‘protɛkta’ (G6PD) de smɔl na di bɔdi? Dɔn dɛn bad tin dɛn de kin kam ɛn bigin fɔ pwɛl wi rɛd blɔd sɛl dɛn. Dis we aw di rɛd blɔd sɛl dɛn kin brok kwik kwik wan pas aw dɛn kin mek dɛn, dɛn kɔl am ɛmolaysis .
We yu lɔs bɔku bɔku rɛd blɔd sɛl dɛn dis kayn we, yu bɔdi nɔ kin gɛt di ɔksijɛn we i nid. Na dat wi kin kɔl anemia, ɔ fɔ tɔk mɔ, hemolytic anemia . Dis na di rizin we mek yu kin fil taya, wik, ɛn yu kin fil lɛk yu bɔdi ɔltɛm.
Aw G6PD dɛfisiɛns kin apin?
G6PD dεfisiεns na wan hεriditri jεnεtik kכndishכn . Dis min se na sɔntin we yu gɛt frɔm yu mama ɛn papa. we mכtεshכn de na di jin we de instrכkt yu fכ mek di G6PD εnzym, di כmכnt fכ dis εnzym we dεn prodyuz na di bכdi de dכn.
Bɔt di impɔtant tin ya na dat nɔto ɔlman we gɛt G6PD dɛfisiɛns go gɛt di sik. Bɔrku pipul dɛn kin liv nɔrmal layf ɛn nɔr gɛt ɛni prɔblɛm. Bɔt sɔm tin dɛn we de kɔmɔt na do (wi kin kɔl dɛn tin ya ‘trig’) kin mek di sayn dɛn we de sho se i sik wantɛm wantɛm.
Trigεr dεm we de trigεr G6PD simptom dεm
Dɛn trig ya kin mek di bɔdi inkrisayz di amount of dɛn bad bad ‘fri radicals’ we wi bin tɔk bɔt wantɛm wantɛm. Pɔsin we nɔ gɛt G6PD nɔ kin ebul fɔ kɔntrol dɛn bad bad tin ya we de bɔku. Na da tɛm de di rɛd blɔd sɛl dɛn kin bigin fɔ brok, ɛn di sayn dɛn kin sho.
| Trig Tayp | Tɔk bɔt |
|---|---|
| Sɔm it dɛn | Fava bins in patikyula wan. Di sik kin kam bay we yu it dɛn ɔ ivin inhal dɛn pɔlin. Dɛn kin kɔl dis kɔndishɔn bak ‘Favism’. |
| Sɔm mɛrɛsin dɛn | Sɔm pen kil lɛk Aspirin, Acetaminophen (Paracetamol), sɔm Sulfa mɛrɛsin, sɔm antibayɔtik ɛn malaria mɛrɛsin na di men wan dɛn. Nɔ tek ɛni mɛrɛsin we yu nɔ gɛt dɔktɔ advays. |
| Vayral ɛn baktriyal infɛkshɔn | Eni infεkshכn, frכm di kכmכn kol to di siriכs infεkshכn, kin trigεr G6PD simptom dεm. |
G6PD dɛfisiɛns kin bɔku pan man dɛm pas uman dɛm, ɛn i kin mɔs pan pipul dɛm we kɔmɔt na Afrika, Eshia, ɛn Mɛditarenian.
Udat nid fɔ gɛt di G6PD tɛst?
Yu dɔktɔ kin tɛl yu fɔ du G6PD tɛst (na simpul blɔd tɛst), mɔ if yu gɛt ɛni wan pan dɛn sik ya:
- Taya ɛn wik we yu nɔ ebul fɔ ɛksplen
- Pale skin
- I nɔ izi fɔ blo ɔ fɔ swɛt
- Di at we de blo
- Di skin ɛn yay we de yɔlɔ (jaundice) .
- Dak urine (we gɛt kola kɔlɔ) .
- Bak ɔ bɛlɛ pen
- Di kayn we aw pipul dɛn de kɔnfyus naw
Tek spɛshal kia fɔ pikin dɛn we dɛn jɔs bɔn.
Na nɔmal tin fɔ mek pikin we dɛn jɔs bɔn gɛt janda. Bɔt if i las fɔ pas tu wiks , di pikin in urine tɔn dak, ɛn di stɔl tɔn pale, di dɔktɔ kin sɔprayz se G6PD nɔ de ɛn du dis tɛst.
Aw fɔ ɔndastand di tɛst ripɔt?
G6PD tɛst rizɔlt kin difrɛn smɔl frɔm wan lab to ɔda lab, so na yu dɔktɔ nɔmɔ go ebul fɔ gi yu di infɔmeshɔn we kɔrɛkt pas ɔl . Bɔt bɔku tɛm, tri kayn tin dɛn de we kin apin.
- Nɔmal: Yu gɛt inof G6PD ɛnzaym na yu bɔdi. Yu nɔ gɛt G6PD dɛfisiɛns.
- mכdarεt Dεfisiεns: di εnzym lεvεl dεm de bitwin 10% εn 60% pan nכmal. Dɛn pipul ya kin jɔs gɛt di sayn dɛm we dɛn gɛt infekshɔn ɔr tek bad bad drɔg riakshɔn.
- Sivεr Dεfisiεns: di εnzym de de na lεs dan 10% pan di nכmal lεvεl dεm. Dɛn pipul ya kin gɛt anemia we nɔ de dɔn ɔ dɛn kin gɛt sɔm sayn dɛn ɔltɛm.
Tritmɛnt ɛn manejmɛnt fɔ G6PD dɛfisiɛns
G6PD dɛfisiɛns nɔto sik we pɔsin kin mɛn ɔltogɛda, bikɔs na jɛnɛtik kɔndishɔn. Bɔt if yu de manej yu fayn fayn wan, yu go ebul fɔ liv fayn layf ɛn yu nɔ go gɛt ɛni prɔblɛm .
De bεst tin wae yu fɔ du na fɔ avɔyd de ‘triggers’ wae de briŋ kam de sik. Dis na di men tritmɛnt.
Yu fɔ:
- Nɔ it fava bins ɔltogɛda.
- Nɔ tek mɛrɛsin fɔ mek yu fil pen lɛk Aspirin ɛn Acetaminophen (Paracetamol) we yu dɔktɔ nɔ gri fɔ tek.
- Tɛl yu dɔktɔ se yu nɔ gɛt G6PD bifo yu gi yu ɛni mɛrɛsin .
- Go to dɔktɔ wantɛm wantɛm if yu gɛt ɛni infekshɔn.
If yu simptom nɔr de, yu dɔktɔ kin gi yu fɔlik asid ɛn ayɛn pils. If yu anemia bad bad wan, yu go nid fɔ go na ɔspitul ɛn gi yu blɔd ɔ ɔksijɛn tɛrapi.
Yu fɔ mɛmba se antiɔksidant lɛk Vitamin E nɔ go ɛp dis kɔndishɔn.
Mɛsej we dɛn kin kɛr go na os
- G6PD dɛfisiɛns na kɔmɔn jɛnɛtik kɔndishɔn we de pas dɔŋ tru jɛnɛreshɔn ɛn nɔto natin fɔ fred.
- Bɔrku pipul dɛn nɔr kin gɛt ɛni sayn atɔl. Di sayn dɛm kin sho we dɛn de pan ‘trig’ lɛk fava bins, sɔm mɛrɛsin, ɔr infɛkshɔn.
- Di men manejmɛnt na fɔ avɔyd dɛn trig ya.
- If yu gɛt G6PD dɛfisiɛns, i impɔtant fɔ tɛl ɛni dɔktɔ bifo yu go to tritmɛnt.
- If yu gɛt sɔm sayn dɛn lɛk fɔ taya pasmak wantɛm wantɛm, yu skin de yɔlɔ, ɔ yu de urine dak, go to yu dɔktɔ wantɛm wantɛm.
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