Sɔntɛnde, yu dɔktɔ kin tɛl yu fɔ du spɛshal tɛst dɛn apat frɔm di blɔd tɛst dɛn we dɛn kin du ɔltɛm, nɔto so? Dɛn kin du dis we di tɛst dɛn we dɛn kin du ɔltɛm nɔ kin du fɔ no sɔm sik dɛn kɔrɛkt wan . Na dat mek dɛn kɔl dis spɛshal blɔd tɛst Serum Immunofixation. Dɛn kin kɔl dis bak di IFE tɛst fɔ shɔt tɛm.
Wetin dis Sɛrum Immunofixation Test de rili luk fɔ?
Fɔ tɔk am simpul wan, dis tɛst de luk pan patikyula kayn prɔtin dɛn we de na yu blɔd.
Tink bɔt dis we: wi bɔdi tan lɛk big faktri. Dis faktri nid ‘wokman’ fɔ mek i kɔntinyu fɔ wok fayn fayn wan. Na so di prɔtin dɛn tan lɛk. dis protin dεm de du bכku wok we rili imכtant, lεk fכ mek wi imyun sistεm strכ ng εn fכ kכri כksijεn כlsay na di bכdi.
Tu men kayn prɔtin dɛn de na wi blɔd. Dɛn na Albumin ɛn Globulin . insay dis imyunofikseshכn tεst, dεn de separet dεn protin dεm ya insay sכm sכm grup dεm. Dɛn kɔl dis prɔses ilɛktrɔfɔrɛsis . Imajin se we yu rol ston dɛn we gɛt difrɛn wet ɛn shep dɔŋ wan slop, dɛn kin muv difrɛn spid ɛn stɔp na difrɛn say dɛn. Dɛn kin yuz ilɛktrik fil fɔ separet dɛn protin ya akɔdin to dɛn wet ɛn ilɛktrik chaj.
we dεn sεparayt dis we, dεn kin no sεvεra mεjכr protin grup dεm.
| Sɔbgrup fɔ di Protɛin | Wan simpul ɛksplen |
|---|---|
| Albumin we dɛn kɔl | Di prɔtin we bɔku pas ɔl na di blɔd. I de ɛp fɔ mek di wata balans na di bɔdi. |
| Alfa-1 globulin we de na di wɔl | I de ɛp fɔ protɛkt di bɔdi tisu ɛn transpɔt tin dɛn lɛk ɔmon. |
| Alfa-2 globulin we de na di wɔl | I gɛt fɔ du wit di ɛnzaym aktiviti ɛn di blɔd we de klɔt. |
| Beta globulin we dɛn kɔl beta globulin | I de ɛp fɔ transpɔt ayɛn ɛn ɔda tin dɛn ɔlsay na di bɔdi. |
| Gama globulin we de na di wɔl | Dis na antibodies, we na wan impɔtant pat pan wi imyun sistɛm. |
Insay di lab, wan spɛshal pɔsin kin ad spɛshal day to dɛn prɔtin dɛn ya we dɛn dɔn ayd ɛn mek dɛn stɛyn. Dɔn dɛn kin si dɛn prɔtin dɛn ya na kɔmpyuta skrin as band. di pik εn vali dεm na dεn bכnd dεm ya kin tεl yu εksεkshכn if yu gεt tu mכ ch כ tu sכm wan patikyula protin na yu bכdi.
di imכtant tin na dat, insay sכm sik dεm, dεn protin pat dεm ya de sho yunik, spεshal chenj dεm. Dis tan lɛk finga prɛnt.
Dis tɛst kin no bak if yu bɔdi de mek nɔmal prɔtin, if dɛn de lɔs frɔm di bɔdi, ɔ if yu de tek di prɔtin fayn fayn wan frɔm di it dɛn we yu de it.
Wetin mek dɛn de aks mi fɔ tek tɛst lɛk dis?
Bɔku rizin dɛn de we mek yu dɔktɔ kin tɛl yu fɔ du dis tɛst. Dɛn kin du am fɔ kɔnfirm di saspek fɔ dɛn sik ya:
| Mɛdikal kɔndishɔn | Fɔ tɔk am simpul wan... |
|---|---|
| Mɔltipɛl Mayloma | Wan kayn wayt blɔd sɛl we de na di bon mɛro kin tɔn to kansa sɛl. Dis na kansa we gɛt fɔ du wit di blɔd. |
| Limfoma we dɛn kɔl Limfoma | kansa we de apin na di limfatik sistεm (di sistεm we de fכt di jεm dεm). |
| Lukimiya | Wan ɔda kansa we kin apin na di blɔd. |
| Kidni sik | fכ no di kes dεm we di protin de kכmכt frכm di kidni dεm tru di urine. |
| Di sik dɛn we pɔsin kin gɛt we i de fɛt insɛf | sik dεm we di bכdi in imyun sistεm de atak in כwn sεl dεm (e.g. rεumatoid atraytis). |
| Liva sik | di chenj dεm na di protin lεvεl dεm bikoz fכ di liva fכnshכn we de wok fayn. |
| Sik dɛm we de na di nervɔs sistɛm | yu kin si abnכmaliti na di protin dεm na sכm nyurolכjik sik dεm. |
| Malnutrishɔn/Malabsɔpshɔn | Nɔ it fayn ɔ nɔ de tek di prɔtin frɔm it. |
Aw yu kin du dis tɛst ɛn ɔndastand di rizɔlt?
Aw yu kin du di tɛst?
Dis na tin we rili simpul. Jɔs lɛk aw dɛn kin du nɔmal blɔd tɛst, dɛn kin tek smɔl blɔd frɔm wan vein we de na yu an. Insay sɔm spɛshal kes dɛm, dɛn kin yuz urine sample bak fɔ kɔnfirm di rizɔlt fɔ di blɔd tɛst.
No spɛshal pripia nɔ de we yu nid fɔ du bifo dis tɛst. Bɔt yu fɔ rili tɛl yu dɔktɔ bɔt ɛni mɛrɛsin, vaytamɛn, ɔ ɔda tin dɛn we yu de tek naw , bikɔs sɔm mɛrɛsin dɛn kin afɛkt di rizɔlt fɔ dis tɛst.
Wetin di rizɔlt dɛn se?
Lɛf am to yu dɔktɔ fɔ ɛksplen yu tɛst ripɔt, bikɔs bɔku tin dɛn, lɛk yu ej, yu man ɔ uman, yu famili mɛdikal istri, ɛn di we aw yu de du di tɛst, kin afɛkt di rizɔlt.
di ripot go sho di rεnj dεm fכ yu protin lεvεl dεm. Wetin impɔtant na if dɛn tin ya nɔmal, smɔl, ɔ ay.
Na mɔtalman, if yu dɔktɔ se "monoclonal proteins" ɔ "M-proteins" de na yu ripɔt, dat kin bi strɔng indikashɔn fɔ wan kansa kɔndishɔn we dɛn kɔl multiple myeloma . Bɔt nɔ wɔri. Yu go nid fɔ du mɔ tɛst fɔ kɔnfɔm am.
Di tin dɛn we kin mek pɔsin gɛt bɔku prɔtin
- Di wata we nɔ de na di bɔdi
- Liva sik
- Inflammatory kondishɔn dɛm lɛk Crohn ’s disease ɔr rεumatoid arthritis
- Kidni sik
- Kɔlestɔl we bɔku
- Anemia we nɔ gɛt ayɔn
- Kansa lɛk Multiple Myeloma ɛn Lymphoma
- Sɔm infɛkshɔn dɛn
Di tin dɛn we kin mek di prɔtin nɔ bɔku
- Alpha-1 antitrypsin deficiency - Dis na wan kכndyushכn we dεn kin gεt we de mek yu gεt lכng sik we i pikin.
- Kidni sik
- Liva sik
- Malnutrishɔn
- Sɔm sik dɛn we pɔsin kin gɛt we i de fɛt insɛf
Ɛni risk de wit dis tɛst?
Nɔto so i bi atɔl. Dis na jɔs wan blɔd tɛst we dɛn kin du ɔltɛm. We dɛn pul di blɔd, yu kin fil sɔm pen ɔ brus na di say we di nidul de. Dis go dɔn kpatakpata insay sɔm awa ɔ wan de. Ɔda pas dat, no ɔda risk nɔ de we gɛt fɔ du wit dis tɛst.
Mɛsej we dɛn kin kɛr go na os
- Serum Immunofixation (IFE) na spɛshal tɛst we de luk dip wan pan di kayn prɔtin dɛn we de na yu blɔd.
- Dis kin ɛp fɔ no kansa lɛk mɔltipɛl mayloma ɛn limfoma, kidni sik, ɛn prɔblɛm wit di imyun sistɛm.
- Nɔ spɛshal prɛparashɔn nɔ nid fɔ de fɔ dis tɛst, bɔt nɔ fɔgɛt fɔ tɛl yu dɔktɔ bɔt ɔl di mɛrɛsin dɛn we yu de tek.
- Tɔk bɔt di tɛst rizɔlt wit yu dɔktɔ fɔ ɔndastand am gud gud wan. Nɔ jomp to kɔnklushɔn fɔ yusɛf.
- Dis na tɛst we rili sef, jɔs lɛk aw dɛn kin du blɔd tɛst ɔltɛm. So nɔ fred am we yu nɔ nid fɔ fred.
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