Obujjanjabi obw'obuyambi ku bulwadde bwa Alzheimer's

Bw’oba ​​olina omuntu mu maka go alina obulwadde bwa Alzheimer ’s Disease, ka kibeere maama wo, taata wo, jjajja wo, oba ssenga wo, osanga okimanyi nti ebintu abyerabira mpolampola. Obwo bwe bubonero obusinga obulaga obulwadde buno. Naye, ng’oggyeeko okufiirwa okujjukira kwabwe, oyinza okuba nga wakirabye enkyukakyuka ennene mu nneeyisa yaabwe. Oluusi bafuna obutawumula, banyiiga, banakuwala oba bamala gatambula kiro nga tebasula. Bw’olaba ebintu bino, era oteekwa okuwulira ennaku ey’amaanyi. Leero twogera ku bujjanjabi obw'enjawulo, oba Adjunct Treatments, obuweebwa ku bizibu by'enneeyisa n'obwongo ebibaawo nga kwotadde n'okubulwa okujjukira mu bulwadde bwa Alzheimer.

Mu ngeri ennyangu, obulwadde bwa Alzheimer bwe bwonoona obutoffaali bw’obusimu mu bwongo, tebukosa kujjukira kwokka wabula n’ebitundu ebifuga enneeyisa yaffe. Eno y’ensonga lwaki ebizibu bino bibaawo.

• Okutabulwatabulwa
• Obulumbaganyi
• Okweraliikirira
• Delusions (okukkiriza ebintu ebitaliiwo) .
• Ennaku
• Okulaba ebintu ebitalabika oba okuwulira ebintu ebitalabika (Hallucinations) .
• Ebbula ly'otulo
• Obutawummula

Obubonero buno buyinza okukuleetera okunyigirizibwa ennyo eri omulwadde ne ggwe, omulabirira. Abasawo batera okukugamba nti osooka kugezaako kuddukanya bubonero buno ng’okyusakyusa mu bulamu n’obujjanjabi bw’enneeyisa nga tonnaddukira mu ddagala. Era olina okusooka okuzuula oba waliwo ekintu ekirala ekivaako enkyukakyuka mu nneeyisa (okugeza, yinfekisoni, obuzibu mu kulaba oba okuwulira, oba ebizibu ebiva mu ddagala eddala).

Naye oluusi eddagala lye lisinga obulungi. Eddagala lingi lye twogerako wano terikkirizibwa nnyo ku bulwadde bwa Alzheimer. Abasawo bawandiika bino "off-label." Kwe kugamba, eddagala erikkirizibwa ku mbeera endala (nga okwennyamira) liweebwa kubanga obumanyirivu bw’omusawo bulaga nti era liyinza okuba nga lituukira ku bizibu by’enneeyisa y’omulwadde wa Alzheimer.

Ebiyamba mu tulo

Abantu bangi bafuna obuzibu mu tulo nga bakaddiwa.Kibaawo. Naye kisinga kubeera mu balwadde ba Alzheimer. Olw’enkyukakyuka mu bwongo, zizuukuka nnyo ekiro ate emisana zikoowa.

Ekisinga obukulu kwe kugezaako okwebaka nga tolina ddagala, okusinga okukozesa empeke ezikweka. Kubanga empeke ez’okwebaka eziweebwa abalwadde ba Alzheimer oluusi ziyinza okuba ez’akabi.

Singa enkyukakyuka mu bulamu tezikuyamba kwebaka, ate ng’okusigala ng’otunula ekiro kikutawaanya nnyo, omusawo akuwe eddagala nga lino:

• Suvorexant (Belsomra): Lino lye ddagala lyokka eryakkirizibwa ekitongole kya Amerika ekya FDA ku buzibu bw’otulo obukwatagana n’obulwadde bwa Alzheimer. Kibeera mu kibinja ky'eddagala eriyitibwa Orexin inhibitors.'' Mu ngeri ennyangu, kikola nga kiziyiza eddagala mu bwongo bwaffe eriraga nti "kye kiseera okuzuukuka." Wabula eddagala lino liyinza okuvaako ebizibu ng’okwebaka, okwennyamira, n’okwebaka emisana.
• Eddagala eddala erikkakkanya: Omusawo ayinza okukuwa empeke endala ezikwebaka, gamba nga Eszopiclone (Lunesta) oba Zolpidem (Ambien). Kyokka, okumira bino kiyinza okukuleetera okukola ebintu ebitali bya bulijjo nga weebase (nga okulya oba okuvuga mu tulo). Era ziyinza okukuleetera okutabulwa emisana, okubulwa okujjukira, n’obulabe obw’okubulwa bbalansi n’okugwa.

Kikulu nnyo: Empeke z’okwebaka zirina okukozesebwa okumala ekiseera ekitono ennyo . Ziyinza okukuziyira n’ofuna otulo amangu. Okwebaka bw’omala okudda mu mbeera eya bulijjo, olina okwogera n’omusawo n’ogezaako okulekera awo okuzimira.

Ate era, empeke ezimu ez’okwebaka (ezirimu eddagala eriweweeza ku buwuka obuleeta endwadde, e.g. diphenhydramine) z’osobola okugula ku ddagala okuva mu maduuka g’eddagala tezisaanira balwadde ba Alzheimer n’akatono . Ziyinza okutaataaganya empuliziganya wakati w’obutoffaali bw’obusimu mu bwongo, ne kyongera okujjukira n’okulowooza.

Eddagala eriweweeza ku kweraliikirira & Eddagala eriweweeza ku kweraliikirira

Okwennyamira nakyo kitera nnyo ku bulwadde bwa Alzheimer. Okusobola okulongoosa embeera y’omulwadde, omusawo ayinza okumuwa eddagala eriweweeza ku kweraliikirira. Eddagala lino teriyinza kuyamba mu kweraliikirira kwokka, wabula n’okweraliikirira, obuzibu mu tulo, okutabulwa, n’okulaba ebirooto.

Okulabula: Eddagala erikadde eriweweeza ku kweraliikirira, gamba nga eddagala eriweweeza ku kweraliikirira erya tricyclic (e.g., amitriptyline) ne SSRI nga paroxetine (Paxil), teriba kirungi eri abantu abalina obulwadde bwa Alzheimer. Ziyinza okwongera okukosa okujjukira n’okulowooza.

Oluusi abasawo bawandiika eddagala ery’ekiseera ekitono eriyitibwa benzodiazepines (e.g., Lorazepam (Ativan), Diazepam (Valium) okujjanjaba okweraliikirira, obutawummulamu, n’enneeyisa ey’obukambwe. Kyokka bino era bisobola okuleeta otulo, okuziyira, okutabulwa, n’obulabe obw’amaanyi obw’okugwa.

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Antipsychotics (eddagala eriwonya okweraliikirira okw’amaanyi n’obuzibu bw’obwongo) .

Ebizibu ebimu eby’enneeyisa ebibaawo n’obulwadde bwa Alzheimer biyinza okuba eby’akabi eri omulwadde oba abamulabirira. Ng’ekyokulabirako, obusungu obuyitiridde, okugezaako okwetuusaako obulabe oba ku balala, n’okulaba oba okuwulira ebintu ebitaliiwo. Mu mbeera ng’ezo, eddagala eriweweeza ku bwongo liyinza okukozesebwa ng’eky’okusembayo, singa tewali ngeri ndala .

Eddagala lino lirina okukozesebwa n’obwegendereza obw’ekitalo, ng’olabirirwa nnyo omusawo. Olw’okuba akabi akayinza okuvaamu kayinza okusinga emigaso, abakugu bagamba nti okubikozesa nga tewali ngeri ndala yonna ebadde ekola.

Nga tonnatandika ddagala lino,

• Okutondawo embeera ey’obukkakkamu
• Okumanyiira enkola
• Okwenyigira mu kukola emirimu gy’omubiri

Mazima ddala wandibadde ogezaako ebintu ng’ebyo.

Eddagala eriweweeza ku bwongo (e.g., Risperidone (Risperdal), Quetiapine (Seroquel), Olanzapine (Zyprexa)) likozesebwa okukola:

• Singa omulwadde aba mu mbeera ey’okweteeka oba abalala mu matigga.
• Singa ekizibu ky’enneeyisa kizibuwalira kuwa bujjanjabi obwetaagisa.
• Bw’oba ​​olina obulwadde obulala obw’omutwe (e.g. schizophrenia ) ng’oggyeeko obulwadde bwa Alzheimer.

Mu ddagala linoWaliwo akabi ak’amaanyi. Kwe kugamba, kyongera emikisa gy’okusannyalala n’okufa mu balwadde abakadde abalina obulwadde bwa Alzheimer. Ng’oggyeeko ekyo, zireeta otulo obw’amaanyi era zongera emikisa gy’okugwa. Okugatta ku ekyo, ebimu ku byo bisobola okuziyiza ekikolwa ky’eddagala eritereeza okujjukira n’okulowooza mu bulwadde bwa Alzheimer, ne kikendeeza ku mugaso gw’eddagala eryo.

Obujjanjabi obulala obw’enjawulo

Ng'oggyeeko eddagala eryogeddwako waggulu, eddagala eddala oluusi likozesebwa "off-label".

• Eddagala eriweweeza ku kuzimba: Eddagala eriweweeza ku kuzimba nga Carbamazepine ne Gabapentin oluusi likozesebwa okufuga okutabulwa mu balwadde ba Alzheimer.
• Eddagala eriweweeza ku bulwadde bwa Parkinson: Eddagala erimu erikozesebwa okujjanjaba obulwadde bwa Parkinson linoonyezebwa okulaba oba liyinza n’okuyamba ku bubonero bwa Alzheimer.