I taksaa he tirhkoh te tak te hi i hria em? (Adrenocorticotropic Hormone - ACTH) (Adrenocorticotropic Hormone) a awm a, a chhuahna tur hmun leh a hmanna tur a awm lo.

I stress emaw, pressure nasa tak i neih emaw hian i taksa chhungah eng nge thleng tih i ngaihtuah ngai em? Kan taksa hian hetiang hun lai hian min puitu kan hmuh theih loh ṭhian tlemte a nei a. ACTH tia koh a ni. Vawiin hian he ACTH chungchang hi kan sawi dawn a ni.

ACTH chu eng nge ni?

A awlsam zawngin ACTH hi i pituitary gland atanga hormone siam a ni. I taksain stress a chhan danah hmun pawimawh tak a chang a ni . ACTH a chhuah hian i adrenal glands te chu cortisol siam turin signal a pe a, chu chu “stress hormone” tia kan hriat vek a ni a, sex hormone pawl pakhat androgens an ti bawk.

Tunah chuan heng hormone te hi eng nge an nih i ngaihtuah mai thei, a dik em? Hormone hi i taksaa hnathawh hrang hrang inzawmkhawmtu chemical a ni. Messenger ang mai an ni. Heng thuchahte hi i thisen kaltlangin i taksa peng hrang hrang, vun, ruh leh taksa peng dangte thlengin a kal a ni. Heng signal te hian i taksa chu eng nge tih tur leh engtikah nge i tih tur tih a hrilh thin.

I pituitary gland hi i thluak bul hnaia awm, hypothalamus hnuai chiaha awm, pea ang maia lian gland te tak te a ni. I endocrine system-a tel a ni. Pituitary gland hian hmun hnih a nei a, chungte chu anterior lobe leh posterior lobe te an ni. I anterior pituitary gland hi ACTH siamtu leh chhuahtu a ni.

ACTH hi eng nge thleng tak tak?

ACTH hnathawh ber chu i adrenal glands te chu hormone cortisol chhuah tir turin a tichak a ni. ACTH hi commanding officer-in i adrenal glands te chu cortisol siam turin a hrilh ang maiin han ngaihtuah teh.

Cortisol hi kan taksa mamawh hormone pawimawh tak a ni. Taksa peng leh tissue zawng zawng deuhthaw a nghawng a ni. Cortisol hi “stress hormone” tia hriat a ni a, mahse a takah chuan kan taksaah hna pawimawh dang tam tak a nei a ni.

Cortisol chungchanga thil pawimawh thenkhat chu hetiang hi a ni:

• I taksain stress a chhan dan chu nangmahin i control a ni .
• I taksain thau, protein, leh carbohydrates a hman dan, chu chu i metabolism .
• Inflammation , taksa peng hrang hranga hring leh sen tihna chu a tlahniam a ni.
• Thisen sang a tidanglam thin .
• Thisen sugar level a tidanglam thin .
• I sleep-wake cycle pawh a tidanglam thei bawk .

Hei mai ni lovin ACTH hian thil dang a ti a ni. Chu chu adrenal glands te chu sex hormone androgens an tih chhuah tir turin a tichak tihna a ni. Hei bakah hian ACTH hian hormone tam zawk siam chhuahna tichaktu chemical siamna kawngah a pui a, chu chu adrenaline leh noradrenaline te hi a ni.

Engtin nge ACTH level hi control a nih?

I taksa ACTH level hi system ngaihnawm takin a control a ni. Feedback system an ti a. I hypothalamus, pituitary gland, adrenal glands leh hormone thenkhat a huam a ni. He system pumpui hi Hypothalamic-Pituitary-Adrenal (HPA) axis tiin kan sawi a ni. A buaithlak deuhin a ri a ni lawm ni? Mahse a awlsam khawp mai.

I pituitary gland chu i hypothalamus nen thisen kalna leh nerve hnah te tak te hmangin a inzawm niin han ngaihtuah teh. Hei hi pituitary stalk an ti a. He stalk hmang hian hypothalamus hian pituitary gland nen an inbia a, hormone thenkhat chhuah tir turin a hrilh thin. I hypothalamus hi i thluak peng pakhat a ni a, thisen sang, heart rate, taksa lum leh vawt leh chaw ei dan te a control thei a ni.

Adrenal glands hi i kal chungah awm, triangular gland te tak te pahnih a ni.

Tunah chuan he ACTH level control tu feedback system hian engtin nge hna a thawh tih kan en ang:

• I taksaa cortisol level a tlahniam chuan i hypothalamus chuan Corticotrophin-Releasing Hormone (CRH) tih hormone a tichhuak a.
• He CRH hian i anterior pituitary lobe chu ACTH chhuah tir turin a tichak a ni.
• Chumi hnuah ACTH hian i adrenal glands, a bik takin adrenal cortex te chu cortisol leh androgens te chhuah tir turin a tichak a ni.
• Hetianga cortisol level a san chuan CRH level tihhniam nan hypothalamus ah signal a thawn kir leh thin. Tin, chutiang chuan cycle chu a zo ta a ni. 'On-off switch' ang mai a ni .

Hei chauh hi ni lovin, i stress lai , chu chu rilru lama i stress lai hian ACTH siamchhuah a tichak a, cortisol level a sang bawk.

Mahse, i hypothalamus, pituitary gland emaw adrenal glands-ah harsatna a awm chuan, chutianga inrawlh hormone, ACTH-te balance chu a tibuai thei a ni.

ACTH level hi engtin nge kan check ang?

I ACTH level enfiah nan thisen test an ti thin. Hei hian i kut chhunga vein pakhat atanga thisen sample tlemte lak a huam a ni.

Doctor-te chuan pituitary gland emaw adrenal glands-ah harsatna a awm leh awm loh hriat nan ACTH test bakah cortisol test an order fo thin.

Tin, doctor-te chuan ACTH stimulation test an tih chu a châng chuan an ti thei bawk. Hei hian i adrenal glands te hian ACTH an chhan dan a test thin. Hei hian pituitary leh/ emaw adrenal glands-a harsatna awmte hriatchhuahna kawngah pawh a pui thei bawk.

ACTH level pangngai chu eng nge ni?

Cortisol ang bawkin i thisena ACTH level hi zing hma takah a sang ber tlangpui. Ni a kal zel chuan a tlahniam zauh zauh a, zanlai velah a hniam ber a thleng thin. Mahse, zan lama hnathawh leh nitin hun hrang hranga i mut chuan he kalphung hi a danglam thei a ni.

Chuvangin ACTH test-ah hian zing lamah thisen lak a ngai tlangpui. A tlangpuiin zing dar 7:00 leh zing dar 10:00 inkar chhunga ACTH level awm zat chu milliliter khatah picogram 7.2 atanga 63.3 (7.2 atanga 63.3 pg/mL) a ni.

Mahse thil pakhat hre reng ang che. Heng normal range te hi lab hrang hrangah te, a hun hunah te, mi hrang hrangah te a inang lo thei a ni. ACTH test i neih chuan i doctor chuan i result a chhiar ang a, test dang neih belh a ngai leh mamawh loh a hrilh ang che.

ACTH level a san chuan eng nge thleng ang?

I ACTH level a san chuan i cortisol level pawh a sang a nih a rinawm. Cortisol hian taksa hi kawng tam takin a nghawng avangin ACTH sang symptoms aiin cortisol sang hian side effects i tawng zawk thei. A then phei chuan i adrenal glands ten cortisol an siam tlem chuan ACTH level a sang thei hle. Chutiang hunah chuan ACTH sang ni lovin cortisol tlahniam symptoms i nei thei.

ACTH level sang lutuk hi chhan hrang hrang a awm thei a:

• Cushing natna: Hei hi ACTH level sang chhan ber a ni. Hei hi pituitary gland-a noncancerous tumor (adenoma) awm vang a ni a, chu chuan ACTH a siam tam lutuk a ni. Chu chuan cortisol level a tisang leh thin. Cushing natna leh Cushing syndrome inthlauhna hi hriatthiam a pawimawh hle . Cushing natna hi Cushing’s syndrome thlentu tam tak zinga pakhat chauh a ni.
• Ectopic adrenocorticotropic hormone tumor: A tlem hle a, i pituitary gland pawna tumor lo awm chuan ACTH a chhuah tam lutuk thei. Chutianga ACTH siam thei tumor (a tlem hle nachungin) chu chu lung cancer ni lo carcinoid tumor , pancreas-a islet cell tumor , thyroid-a medullary carcinoma , lung-a small cell tumor, leh thymus gland-a tumor te hi a ni.
• Primary adrenal insufficiency: Hetiang dinhmun hi thil engemaw takin i adrenal glands a tihchhiat a, cortisol a siam tha thei lo a nih chuan a thleng thin. Addison natna a niHei hi primary adrenal insufficiency thlentu ber a ni. Chuvang chuan i pituitary gland hian ACTH a tichhuak tam zawk a, a chhan chu adrenal glands te tihchak a duh vang a ni.

ACTH level a tlahniam chuan eng nge thleng ang?

Pituitary gland-a harsatna avanga ACTH level a hniam chuan cortisol level pawh a hniam tlangpui ang. Mahse, adrenal gland-a harsatna awm avanga cortisol level a san chuan ACTH level a hniam thei.

ACTH level a hniam theih chhan hrang hrang a awm a:

• Cushing’s syndrome: Cushing’s syndrome hi adrenal gland tumor vang emaw, hun rei tak chhung corticosteroid damdawi hman avanga natna dang atana hman a nih vang emaw hian ACTH level a tlahniam thei a ni. Hei hi i pituitary gland hian cortisol tam lutuk vangin ACTH chu a pangngaiin a chhuah thei lo vang a ni.
• Hypopituitarism: Hei hi thil awm lo tak a ni. Hei hi i pituitary gland-in hormone pakhat, engemaw zat, a nih loh leh a zawng zawng a siam chhuah tlem lutuk hian a ni. ACTH hi a nghawng thei hormone pakhat a ni. I pituitary gland chhiatna eng pawh, tumor, surgery emaw, radiation therapy emaw ang chi hian hypopituitarism a thlen thei a ni.

Tunah chuan ACTH hi i cortisol level tihreh nan a pawimawh hle tih i hre tawh mai thei. Cortisol level sang emaw hniam emaw symptoms i neih chuan i taksa rihna sang emaw tlahniam emaw, thisen sang sang emaw hniam emaw i neih chuan doctor pan ngei ngei tur a ni. I natna lan chhuahna chhan chu i adrenal glands emaw pituitary gland emaw a nih leh nih loh hriat nan cortisol leh ACTH thisen test a kalpui thei a ni.

Chuti a nih chuan eng thil nge kan hriat reng tur?

ACTH hi pituitary gland atanga siam hormone pawimawh tak a ni a, kan taksaa stress control turin a pui a ni.

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- Hei hian adrenal glands te chu "stress hormone" cortisol siam chhuah tirtu a ni.

- Cortisol hian thil tam tak a control a, chu chu kan metabolism, thisen sang, leh thisen sugar level te hi a ni.

- ACTH level hi complex system hmanga control a ni a, chu chu hypothalamus, pituitary gland, leh adrenal glands te a ni .

- ACTH level a san emaw a tlahniam emaw a nih chuan Cushing natna, Addison natna a thlen thei.Hriselna lama harsatna hrang hrang a awm thei.

- Hemi kawngah hian symptom i neih chuan hlau lova doctor pan a, thurawn lak a tha ber.

` ACTH, Adrenocorticotropic Hormone, Cortisol, Pituitary gland, Adrenal glands, Hormone, Stress te hi a awm thei lo