I nu emaw, i pa emaw, i pi emaw, i pi emaw hriatrengna chu an upat deuh deuh chuan a tlahniam tih i hmu ngai em? A chang chuan hei hi "kan tar dan chauh" tiin kan ngai thin a, mahse chutiang chu a ni ngai lo. Hetianga hriatrengna hloh zauh zauh hi a chang chuan Alzheimer natna chhinchhiahna a ni thei. Thu sawi ila, he natna hi hmeichhiaah a tam zawk tih i hre tawh ngei ang. Chu thawnthuah chuan thudik a awm tak tak em? Engvangin nge hetiang hi a lo awm? Vawiin hian he thu hi awlsam tak leh friendly takin i sawi dawn nia.
Alzheimer natna hi hmeichhiaah a tam zawk tak tak em?
Ni e, chu thawnthu chu a dik a ni. Khawvel hmun hrang hranga statistics i en chuan Alzheimer natna vei hmun thuma ṭhena hmun hnih vel chu hmeichhia an ni. Chumi awmzia chu hmeichhe kum 65 chunglam paruk zinga pakhat chu he natna hi kai theihna a ni tihna a ni.
Ngaihtuah teh, dementia hi chi hrang hrang a awm a. Mahse mithiamte chuan Alzheimer natna avanga lo awm lo dementia chi dang hian hmeichhia leh mipa a vei ve ve tih an hmuchhuak. Chu chu Alzheimer natna leh hmeichhiate inkarah hian inzawmna bik a awm tihna a ni . Chuvangin hmeichhiate hi engvangin nge risk sang zawk an neih tih hi han en ila.
Engvangin nge hmeichhiate hi an hlauhawm zawk nia sawi?
Hei hi chhan hrang hrang a awm a. Chhan pakhat ni lovin, chhan tam tak inzawmkhawm a ni.
1. Hmeichhia dam rei zawng tihpun
A awlsam zawngin sawi ila, a chhan ber chu hmeichhiate hi a vaiin mipa aiin an dam rei zawk vang a ni. Hmeichhia dam rei zawng chu kum 81 vel a ni a, mipa tan chuan kum 76 vel a ni thung. Alzheimer natna vei theihna tur risk factor lian ber chu tar hi a ni . Chuvangin hmeichhiate an dam rei zawk avangin natna vei theihna hun an nei tam zawk a ni.
Mahse thawnthu hi chutiang chuan a tawp lo. Kum inang hmeichhia leh mipa pawl hrang hrangah zirchianna an nei bawk a, hmeichhiate hian Alzheimer’s an vei tam zawk tih hmuhchhuah a ni. Chumi awmzia chu kum chauh ni lovin chhan dang a awm tihna a ni.
2. Immune system a inthlak danglam
Hmeichhia te hi mipa aiin a chak zawk niin an sawi. Hei vang hian hmeichhiate hian autoimmune diseases an vei theihna hi a let hnih zetin an tam zawk a ni.
Tunah chuan, hei hi Alzheimer natna nen a inzawm dan chu hetiang hi a ni. Alzheimer natna thlentu protein pawimawh tak chu amyloid a ni. Zirchiangtute chuan kan thluaka natna hrik lutte do turin taksain he protein hi a siam chhuak thei niin an ngai. Hmeichhia immune system a active zawk avangin he amyloid protein hi an thluak ah a awm duh zawk a ni . Hei hi hmeichhiaten he natna an vei tam chhan pakhat a ni.
3. Hormone-te nghawng dan
Estrogen hi hmeichhe hormone lian tak a ni. He hormone hian kan central nervous system a humhim thei a ni. Alzheimer’s ang natna laka invenna atan a pui bawk a, a hmaa kan sawi tawh amyloid protein pawh a tichhia bawk.
Hmeichhiain menopause a paltlang hian heng estrogen level te hi a tlahniam nghal vat thin . Mak tak maiin, menopause hnuah chuan mipa upa zawk estrogen level hi hmeichhe upa zawk aiin a sang tak tak thei a ni.
Zirna thenkhatah chuan hormone replacement therapy (HRT) hian hlawkna a awm tih hmuhchhuah a nih laiin, thenkhatah chuan hlawkna a awm lo. Tin, HRT hi stroke ang chi hlauhawmna nen a inzawm a, chuvangin thutlukna i siam hmain i doctor nen sawiho hmasak a pawimawh hle.
4. Thluak insiam dan leh hnathawh dan inthlak danglam
Hmeichhia leh mipa thluak insiam danah hian danglamna tlem a awm a. A tlangpuiin mipa thluak hian volume lian deuh deuh a nei a. Chumi avang chuan mipa hian Alzheimer natna thlentu thilte chu tuar thiamna nasa zawk an nei thei a ni.
Research atanga a lan dan chuan thluak peng pakhat, hriatrengna lama hmun pawimawh tak changtu hippocampus hi mipa aiin hmeichhiaah a tlahniam (atrophy) zawk tih hmuhchhuah a ni.
| Hmeichhia tana risk tipungtu thil | Hrilhfiahna awlsam tak |
|---|---|
| Genetic Factors te hi a ni | APOE gene variant hi hmeichhiaah Alzheimer’s vei theihna tur risk factor chak tak a ni tih hmuhchhuah a ni. Hetiang gene nei hmeichhia hian gene inang nei mipa aiin he natna hi a vei tam zawk. |
| Chak lohna | Hmeichhia an tar chhoh zel chuan kum inang mipa aiin taksa lamah an chak lo zawk thin. Hetiang chak lohna, taksa rihna tlahniam leh hah fo hian Alzheimer’s vei theihna a tipung a ni. |
| Khawtlang nun (Social Factors) te | Zirna, sum lakluh tam zawk, hnathawhna leh taksa tihchakna te hian thluak "cognitive reserve" a tipung a ni. Tun hma chuan hmeichhe tam tak chuan mipa angin chanvo an nei lo. Hei hian an tar chhoh zel chuan hriatrengna tlahniam chu an tuar thei lo thei a ni. |
| Naupai laiin harsatna a awm thin | Naupai laiin thisen sang (preeclampsia) ang chi natna hian naupan laiah dementia vei theihna a tipung niin an ngai. Hemi chungchangah hian zirchianna neih belh a ngai a ni. |
Thluak "cognitive reserve" chu eng nge ni?
Hei hi thil pawimawh tak a ni. I thluak hi bank account angin ngaihtuah rawh. I zir hian, thil thar i zir hian, i socialize hian, exercise i tih hian he account-ah hian "resources" i dah belh tihna a ni. Hei hi cognitive reserve kan tih chu a ni.
Kan tar chhoh zel a thluak a chhe tan chuan hetiang reserve nei hian chu chhiatna chu tuar theiin a thawk tha chhunzawm zel thei a ni. Tun hma chuan hmeichhiate hian zirna leh hnathawhna lama hun remchang an nei tlem zawk a, hei hian he reserve hi an din theihna chance a ti tlem a ni. Hei hi tunlai hmeichhe kum upa lam zingah Alzheimer natna vei tamna chhan indirect a ni thei bawk.
Take-Home Thuchah a ni
- Alzheimer natna hi mipa aiin hmeichhiaah a tam zawk a, an dam rei vang chauh a ni lo.
- Hmeichhia hormone level inthlak danglamna (a bik takin estrogen tlahniam), genetic factors, immune system function, leh thluak structure inthlak danglamna fiah lo tak takte hi a puitu zawng zawng a ni.
- Tun hmaa hmeichhiate tana zirna leh khawtlang nun remchang an neih loh avangin he hlauhawmna hi indirect-in a nghawng thei a ni.
- Thluak chak taka vawn reng te, zirlai te, inpawh tawnna te, nun hrisel taka nunpui te hian thluak hriatna (cognitive reserve) a tipung thei a ni.
- Nangmah emaw, i chhungte zinga tu emaw chuan hriatrengna lama harsatna i neih chuan ngaihthah suh . I chhungkaw doctor nen sawiho la, thurawn la rawh. Hriatchhuah hmasak hi enkawlna kawng pawimawh tak a ni.
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