I chhungkuaa mi tu emaw, i nu duh tak, i pa, i pi emaw, i pi emaw, zawi zawiin thil a theihnghilh zel tih i hre ngai em? A tirah chuan thil tenau te, mahse a hnua thil pawimawh an theihnghilh chuan kan hlauthawng deuh vek thin. Hetiang dinhmun hi Alzheimer’s Disease kan tih fo thin chu a ni. Thil buaithlak tak leh lungngaihna thlen thei tak a ni. Mahse chanchin lawmawm tak chu khawvel hmun hrang hranga doctor leh scientist-te chuan he natna hi a chinfel dan tur zawngin zan tin an thawk chhuak a ni. Vawiin hian he zirchianna hian beiseina thar min pek chungchang hi han sawi ila.
Engvangin nge Alzheimer zirchianna hi a pawimawh em em?
A awlsam zawngin sawi ila, Alzheimer natna hi thluak cell te tichhe zauh zauh a, hriatrengna, ngaihtuahna leh nitin hna thawh theihna te a thlen a ni. Hei hi thluaka protein pangngai lo , amyloid beta plaques an tihte a lo awm khawm vang a ni. Kan thluaka nerve cell inkara information phurtu kawngpuiah bawlhhlawh leh bawlhhlawh awmkhawm ang maiin ngaihtuah la, chu kawng chu a tikhawlo a ni. Chu chu heng proteins te chungah hian a thleng thin.
Tun thlengin he natna hi damdawi hmuh tur a la awm lo. Chuvangin research hi kan beiseina lian ber a ni . Khawvela damdawi siamtu company lar tak tak te, American sorkar ang institution te, Alzheimer’s Association ang pawl te hian he zirchiannaah hian sum tam tak an seng a ni. Tum lian pathum an nei a, chungte chu:
1. Natna lanchhuahna tiziaawm thei damdawi zawng chhuah.
2. Natna laka inven dan tur zawn.
3. Natna kai tawhte tan damna famkim pek.
Research atanga thil pawimawh tak takte
He natna hi zirchiangtute chuan angle hrang hrang atangin an thlir a. Puzzle lian tak chinfel ang bawkin, a sir zawng zawng atanga thu hriatte an dah khawm a, chu chuan thlalak kimchang tak chu an siam a ni.
Natna vei theihna tipungtu thil
Mi thenkhat chu midang aiin Alzheimer’s vei an tam zawk. Researcher-te chuan heng risk factors te hi ngun takin an zirchiang mek a, a chhan chu a chhan hriatchhuah hian natna venna kawngah a pui thei a ni.
| Risk Factor a ni | A sawifiahna awlsam tak |
|---|---|
| Kum upa lam | Hei hi risk factor ber a ni. Kum 65 hnuah chuan a hlauhawmna a pung zauh zauh a, mahse, kum upa lam zawng zawng hian he natna hi an vei vek lo. |
| Chhungkaw chanchin leh genetics | I nu emaw, i pa emaw, i unaupa emaw hian he natna hi a nei a nih chuan nang pawh i hlauhawm thei a ni. Gene thenkhat chuan a nghawng a ni. |
| Lu hliam na tak a awm | Tleirawl lai emaw, engtik lai pawha lu hliam na tak (a bik takin hriatna hloh thlentu) chuan nakin lawkah a hlauhawmna a tipung thei a ni. |
| Zirna level hniam | Zirna leh thluak chak taka hnathawh fo hian thluak cell hrang hrangte inzawmna network nghet tak a siam a ni. Hei hian zirna nei tlem zawkte chu an hlauhawmna a sang zawk thei tih hmuhchhuah a ni ta a ni. |
Enkawlna pawm tharte
Hei hi a beiseiawm ber a ni. Tun hnaiah US Food and Drug Administration (FDA) chuan thluaka amyloid beta plaques target leh paih chhuak thei damdawi pahnih a pawm a, chu chu kan sawi tawh ang khan Alzheimer natna thlentu ber a ni.
1. Aducanumab-avwa (Aduhelm) 1. A rilru a hah lutuk chuan a rilru a buai em em a.
2. Lecanemab-irmb (Leqembi) tih hi a awm a.
Natna tidam vek ai chuan heng damdawi te hian natna zual zelna tikhawtlai a, thluak atanga protein tha lo tak tak te chu a paih chhuak thei a ni. Hei hi Alzheimer natna enkawlna kawngah hmasawnna lian tak nia ngaih a ni.
He damdawi hi Sri Lanka-ah hian a la awm lo mai thei a, mahse hetiang zirchianna atanga kan hmuh avang hian nakin lawkah chuan enkawlna hlawhtling zawk a lo chhuak ngei kan beisei thei a ni.
Natna laka invenna atana puitu thil
Research hian risk factors chauh a zawng lo va, natna laka invenna atana puitu ‘protective factors’ te pawh a zawng a ni.
- NSAID hman dan: Nonsteroidal anti-inflammatory drugs (NSAIDs) hi natna leh inflammatory tihziaawmna atana kan hman damdawi, ibuprofen leh diclofenac te hi a ni. Zirna hrang hrangah chuan an hman dan leh Alzheimer’s vei theihna tihhniamna inzawmna a awm tih hmuhchhuah a ni. Mahse hei hi a pawimawh hle: chhan awm lovinAlzheimer natna laka inven nan hetiang damdawi hi doctor thurawn tel lo chuan ei loh tur a ni. Side effect dang a thlen thei bawk.
- Antioxidants: Hengte hi free radicals dotu, kan taksa chhunga cell awmte tichhe thei thil a ni. Thei, thlai leh dark berries-ah te an tam hle. Hei vang hian balanced diet hi a pawimawh em em a ni.
- Thluak chak taka vawn reng: Zirna sang zawk neih te, hna buaithlak tak tak thawh te, thil thar ( tawng, musical instrument) zir te, puzzle chinfel te, etc. te hian thluak hi a tichak reng a ni. Hei hian thluak ‘cognitive reserve’ a tipung a, natna lan chhuah dan a tikhawtlai thei bawk.
Engtin nge heng thilte hi kan nunah kan belhchhah theih ang?
Khawvela khawi hmunah pawh research awm se, a rawn thlen hriatna chu kan nunah kan hmang thei a ni. I emaw, i hmangaih tak emaw thluak hriselna i ngaihtuah a nih chuan heng thilte hi ngaihtuah rawh.
- Nun hrisel: Meizial zuk loh tur. Thisen sang, cholesterol, leh zunthlum te control. Hengte hi thinlung natna bakah Alzheimer natna vei theihna tur risk factor an ni.
- Ei leh in inthlau tak: Oil, sugar leh chi te tihtlem la, thlai, thei, legumes, leh sangha ang chi thil te chu i eitur ah te dah tel bawk ang che.
- Exercise: Nitin kea kal ang chi thil awlsam tak pawh hian thluaka thisen supply tha tak a neih theih nan a pui thei a ni.
- Rilru lama thawkrim: Chanchinbu chhiar la, lehkhabu chhiar la, puzzle chingfel la, thiante nen inbiakna nei la, social takin awm rawh. Heng zawng zawng hi thluak tan exercise tha tak a ni.
A pawimawh ber chu nangmah emaw i chhungte zinga mi emaw hian hriatrengna lama harsatna nei nia i rinhlelh chuan "kum upat dan ang chiah" tiin hnawl suh la , doctor pan nghal rawh Natna hi a hriat hma poh leh enkawlna atanga result tha zawk i hmu thei ang. Uluk takin a enfiah ang che a, a tul chuan neurologist hnenah a refer ang che.
Take-Home Thuchah a ni
- Alzheimer natna hi thluaka natna zual zel a ni a, mahse zirchianna thar beisei awm tak tak a awm nual.
- Tun hnaia damdawi pawmpui Aduhelm leh Leqembi te hi natna bulpui ber an beih avangin hmasawnna lian takah ngaih a ni.
- Kum leh chhungkaw chanchin ang chi risk factors te chu kan thlak danglam thei lo nain, nunphung hrisel taka nun te, ei leh in inthlau tak ei te, exercise lak te, leh kan thluak active taka awm tir te hian kan risk hi kan tihtlem thei a ni.
- Nangmah emaw, i hnaih ber emawin hriatrengna lama harsatna i neih chuan ngaihthah suh la , i chhungkaw doctor pan nghal rawh.A hmaa hriat chian a pawimawh hle.
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