I doctor hian cancer natna enkawl nan nangmah emaw, i hnaih ber emaw tan ‘Antimetabolite’ damdawi a pe em? Chutiang a nih chuan he damdawi chi hrang hrang, a thatna leh that lohna te, a hnathawh dan te hi hriat vek i duh mai thei. Antimetabolites hi damdawi chi khat, chemotherapy-a cancer tihhlumna atana hman thin a ni. Dik tak chuan damdawi chi hlui tak, cancer enkawlna atana hman lar tak an ni a, kum 1940 chho atang khan an lo hmang tan tawh a ni.
Heng antimetabolites te hi engte nge ni? Engtin nge hna an thawh?
A awlsam zawngin sawi ila, antimetabolites hi damdawi chi khat , cell tichhe thei (cytotoxic) . An thiltih hi a fiah lo hle mai.
Ngaihtuah teh, kan taksaa cell pakhat, a bik takin cancer cell hian a thang lian tur, a inthen darh tur leh a pung zel tur chuan a ‘ingredients’ thenkhat a mamawh a ni. He damdawi hian a tih chu chutiang thil chi hrang hrang ang chiah chiah ‘fake ingredient’ angin a thawk a ni. Chuvangin cancer cell te chu bum an ni a, an thanlenna atana an mamawh thil tak tak ai chuan heng thil lem, kan damdawi te hi an ei ta zawk a ni.
Cell pakhata genetic information, chu chu chu cell blueprint kimchang tak chu DNA leh RNA tih thilteah a awm a ni. He antimetabolite damdawi hi cancer cell chhunga a luh chuan chu cell chuan a DNA copy a siam thei lo. Printer-a cartridge dik lo dah a, copy a siam thei lo ang mai a ni.
DNA copy theih loh chuan chu cell chu cell tharah a inthen thei lo. Cancer cell te chu an pung zel tawh lo va, an thi ta a ni.
Because this type of drug specifically targets rapidly dividing cells , cancer chak taka lo thang lian control-na kawngah an thawk tha hle.
A hnuaia tarlan te hi cancer enkawlna atana hman tlanglawn antimetabolite thenkhat an ni.
| Antimetabolite hman tlanglawn thenkhat |
|---|
| 6-mercaptopurine a ni |
| Fludarabine hmanga siam a ni |
| 5-fluorouracil a ni |
| Gemcitabine hman a ni |
| Cytarabine hman a ni |
| Pemetrexed a ni |
| Methotrexate hmanga siam a ni |
He damdawi hi eng cancer chi hrang hrangah nge hman a nih?
Antimetabolites hi thisen cancer enkawlna atan hman a ni ber a , chu chu leukemia , hnute cancer , ovarian cancer leh intestinal tract cancer te a ni
Mahse heng damdawi te hian cell chi hrang hrang, rang taka inthen darh zel tur chu a tikhawlo thei a, chuvangin doctor-te chuan cancer chi dang hrang hrang tan pawh an rawt bawk.
Engtin nge he damdawi hi ka hmuh theih ang?
Antimetabolite damdawi pek dan hi damdawi sawi tur leh cancer enkawl mek chi hrang hrang a zirin a danglam thei.
- Tablet emaw liquids: Antimetabolite thenkhat chu tablet emaw liquid angin nitin ka atanga ei theih a ni.
- Intravenous (IV): Injection chi dang pawh a awm a, chu chu vein pakhatah an pe a. Hengte hi vein kaltlangin saline solution angin pek thin a ni. Hun rei tak enkawl mek tan chuan heng damdawi te hi a chang chuan special tube (mediport) hmanga pek a ni a, chu chu vein lian tak, central vein-ah dah a ni.
- Creams: Skin cancer atana hman thin antimetabolites te hi topical cream angin a awm bawk. Hengte hi vun natna hmunah ni khatah vawi khat emaw vawi hnih emaw hnawih thin a ni.
He enkawlna hian eng hlawkna leh hlauhawmna nge a neih?
Hetiang damdawi chi hrang hrang thatna lian ber chu cancer cell a tichhia a, cancer thanna a titawp emaw, a ti tlem emaw a ni. Hei hian damlo chu a dam leh theih nan a pui a, a dam rei thei bawk.
Mahse, risk a awm a ni. Heng damdawi te hian mi zawng zawng tan hna a thawk dan inang vek lo. A châng chuan doctor-te pawhin he damdawi hi eng cancer nge a nih tih chiang taka hriat an harsat ṭhin.
Thil pawimawh dang chu a chang chuan a tir lamah tha takin thawk mahse hun kal zelah cancer cell te hian he damdawi hi an hmang thiam ta thin a ni. Hei hi ‘resistant’ kan ti a. Tichuan damdawi chuan hna a thawk thei tawh lo.
Antimetabolites hian eng side effect nge a neih?
Antimetabolites hi damdawi chi khat a nih avangin damdawi pakhat chauh a nih loh avangin a side effect pawh a inang lo thei. Chuvangin, antimetabolite damdawi bik pek i nih chuan a kaihhnawih side effect bikte chu i doctor nen inbiakna neih a pawimawh hle.
Mahse a tlangpuiin antimetabolite tam zawkah hian side effect hmuh tur awm fo engemaw zat a awm.
| Side Effect a awm thei | Hrilhfiahna |
|---|---|
| Digestive system lama harsatna awm thei | Luak chhuak, luak chhuak, ei duh lohna, ril\am, emaw, chaw ei kham loh. |
| Taksa a nuam lo | Chauhna, chak lohna, taksa ruh na, lu na, leh luak chhuak. |
| Kawng leh hmuiah inthlak danglamna | Kawng leh hmuiah hliam emaw, hliam emaw a awm. |
| Liver-a nghawng a neih dan | Liver enzymes sang (hei hian liver a chhiat emaw, a hring emaw a tilang thei). |
| Vun leh sam | Sam tlakchham, vun hring, vun vawt leh chhe tawh. |
| Mit a inthlak danglam thin | Mit hmuhna a inthlak emaw, êng laka sensitivity emaw a awm. |
| Thisen cell-a nghawng a neih dan | Thisen var cell count a tlahniam a, chu chuan hri kai theihna a tipung a ni. |
Take-Home Thuchah a ni
- Antimetabolites hi chemotherapy damdawi chi khat a ni a, cancer cell te chu an lo thang lian zel theih nan a bum a, chutianga an tih theih lohna tur a titawp thin.
- Hengte hi cancer lian tham tak tak, leukemia, hnute, ovarian, leh colon cancer te tan hman a ni ber.
- Heng enkawlnate hian cancer cells tichhe thei khawpa thatna nei mahse, damdawi laka invenna leh side effects te pawh a keng tel bawk.
- Damdawi hrang hrangah side effect a inang lo avangin damdawi i ei tur leh a nghawng dan hriat a pawimawh hle.
- A pawimawh ber: Damdawi an pek che te, a side effect te, leh zawhna emaw, ngaihtuahna emaw i neih te chu hreh lovin i doctor nen inbia ang che. Amah chauhvin thurawn dik leh dik ber a pe thei che a ni.
💬 Comments (0)
Comment a la awm lo. Hetah hian i comment hi a vawikhatna atan add rawh.
I comment kha add rawh