I doctor hian cancer natna enkawl nan nangmah emaw, i hnaih ber emaw tan ‘Antimetabolite’ damdawi a pe em? Chutiang a nih chuan he damdawi chi hrang hrang, a thatna leh that lohna te, a hnathawh dan te hi hriat vek i duh mai thei. Antimetabolites hi damdawi chi khat, chemotherapy-a cancer tihhlumna atana hman thin a ni. Dik tak chuan damdawi chi hlui tak, cancer enkawlna atana hman lar tak an ni a, kum 1940 chho atang khan an lo hmang tan tawh a ni.
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Heng antimetabolites te hi engte nge ni? Engtin nge hna an thawh?
A awlsam zawngin sawi ila, antimetabolites hi damdawi chi khat , cell tichhe thei (cytotoxic) . An thiltih hi a fiah lo hle mai.
Ngaihtuah teh, kan taksaa cell pakhat, a bik takin cancer cell hian a thang lian tur, a inthen darh tur leh a pung zel tur chuan a ‘ingredients’ thenkhat a mamawh a ni. He damdawi hian a tih chu chutiang thil chi hrang hrang ang chiah chiah ‘fake ingredient’ angin a thawk a ni. Chuvangin cancer cell te chu bum an ni a, an thanlenna atana an mamawh thil tak tak ai chuan heng thil lem, kan damdawi te hi an ei ta zawk a ni.
Cell pakhata genetic information, chu chu chu cell blueprint kimchang tak chu DNA leh RNA tih thilteah a awm a ni. He antimetabolite damdawi hi cancer cell chhunga a luh chuan chu cell chuan a DNA copy a siam thei lo. Printer-a cartridge dik lo dah a, copy a siam thei lo ang mai a ni.
DNA copy theih loh chuan chu cell chu cell tharah a inthen thei lo. Cancer cell te chu an pung zel tawh lo va, an thi ta a ni.
Because this type of drug specifically targets rapidly dividing cells , cancer chak taka lo thang lian control-na kawngah an thawk tha hle.
A hnuaia tarlan te hi cancer enkawlna atana hman tlanglawn antimetabolite thenkhat an ni.
| Antimetabolite hman tlanglawn thenkhat |
|---|
| 6-mercaptopurine a ni |
| Fludarabine hmanga siam a ni |
| 5-fluorouracil a ni |
| Gemcitabine hman a ni |
| Cytarabine hman a ni |
| Pemetrexed a ni |
| Methotrexate hmanga siam a ni |
He damdawi hi eng cancer chi hrang hrangah nge hman a nih?
Antimetabolites hi thisen cancer enkawlna atan hman a ni ber a , chu chu leukemia , hnute cancer , ovarian cancer leh intestinal tract cancer te a ni
Mahse heng damdawi te hian cell chi hrang hrang, rang taka inthen darh zel tur chu a tikhawlo thei a, chuvangin doctor-te chuan cancer chi dang hrang hrang tan pawh an rawt bawk.
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Check Availability →Engtin nge he damdawi hi ka hmuh theih ang?
Antimetabolite damdawi pek dan hi damdawi sawi tur leh cancer enkawl mek chi hrang hrang a zirin a danglam thei.
- Tablet emaw liquids: Antimetabolite thenkhat chu tablet emaw liquid angin nitin ka atanga ei theih a ni.
- Intravenous (IV): Injection chi dang pawh a awm a, chu chu vein pakhatah an pe a. Hengte hi vein kaltlangin saline solution angin pek thin a ni. Hun rei tak enkawl mek tan chuan heng damdawi te hi a chang chuan special tube (mediport) hmanga pek a ni a, chu chu vein lian tak, central vein-ah dah a ni.
- Creams: Skin cancer atana hman thin antimetabolites te hi topical cream angin a awm bawk. Hengte hi vun natna hmunah ni khatah vawi khat emaw vawi hnih emaw hnawih thin a ni.
He enkawlna hian eng hlawkna leh hlauhawmna nge a neih?
Hetiang damdawi chi hrang hrang thatna lian ber chu cancer cell a tichhia a, cancer thanna a titawp emaw, a ti tlem emaw a ni. Hei hian damlo chu a dam leh theih nan a pui a, a dam rei thei bawk.
Mahse, risk a awm a ni. Heng damdawi te hian mi zawng zawng tan hna a thawk dan inang vek lo. A châng chuan doctor-te pawhin he damdawi hi eng cancer nge a nih tih chiang taka hriat an harsat ṭhin.
Thil pawimawh dang chu a chang chuan a tir lamah tha takin thawk mahse hun kal zelah cancer cell te hian he damdawi hi an hmang thiam ta thin a ni. Hei hi ‘resistant’ kan ti a. Tichuan damdawi chuan hna a thawk thei tawh lo.
Antimetabolites hian eng side effect nge a neih?
Antimetabolites hi damdawi chi khat a nih avangin damdawi pakhat chauh a nih loh avangin a side effect pawh a inang lo thei. Chuvangin, antimetabolite damdawi bik pek i nih chuan a kaihhnawih side effect bikte chu i doctor nen inbiakna neih a pawimawh hle.
Mahse a tlangpuiin antimetabolite tam zawkah hian side effect hmuh tur awm fo engemaw zat a awm.
| Side Effect a awm thei | Hrilhfiahna |
|---|---|
| Digestive system lama harsatna awm thei | Luak chhuak, luak chhuak, ei duh lohna, ril\am, emaw, chaw ei kham loh. |
| Taksa a nuam lo | Chauhna, chak lohna, taksa ruh na, lu na, leh luak chhuak. |
| Kawng leh hmuiah inthlak danglamna | Kawng leh hmuiah hliam emaw, hliam emaw a awm. |
| Liver-a nghawng a neih dan | Liver enzymes sang (hei hian liver a chhiat emaw, a hring emaw a tilang thei). |
| Vun leh sam | Sam tlakchham, vun hring, vun vawt leh chhe tawh. |
| Mit a inthlak danglam thin | Mit hmuhna a inthlak emaw, êng laka sensitivity emaw a awm. |
| Thisen cell-a nghawng a neih dan | Thisen var cell count a tlahniam a, chu chuan hri kai theihna a tipung a ni. |
Take-Home Thuchah a ni
- Antimetabolites hi chemotherapy damdawi chi khat a ni a, cancer cell te chu an lo thang lian zel theih nan a bum a, chutianga an tih theih lohna tur a titawp thin.
- Hengte hi cancer lian tham tak tak, leukemia, hnute, ovarian, leh colon cancer te tan hman a ni ber.
- Heng enkawlnate hian cancer cells tichhe thei khawpa thatna nei mahse, damdawi laka invenna leh side effects te pawh a keng tel bawk.
- Damdawi hrang hrangah side effect a inang lo avangin damdawi i ei tur leh a nghawng dan hriat a pawimawh hle.
- A pawimawh ber: Damdawi an pek che te, a side effect te, leh zawhna emaw, ngaihtuahna emaw i neih te chu hreh lovin i doctor nen inbia ang che. Amah chauhvin thurawn dik leh dik ber a pe thei che a ni.
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