Blastocyst a tawi zawngin: Naupai hrisel tak neih theihna tura hmalakna hmasa ber (Blastocyst) .

Fa neih beisei mi i nih chuan, a bik takin nau pai theih lohna enkawl mek i nih chuan i doctor hnen atangin ‘Blastocyst’ tih thumal hi i hre tawh ngei ang. He thumal hi hriat a ni fo a, a bik takin IVF ang chi enkawlna chungchang sawi hian a hriat fo thin. He thu i hriat hian i tan chuan scientific deuh leh buaithlak deuhin a lang mai thei. Mahse, hlau suh. A awlsam zawngin, hei hi i beiseina bul tanna te ber, mahse pawimawh tak a ni. Vawiin hian he Blastocyst hi eng nge a nih, eng nge a tih, naupai atana a pawimawh zia te hi awlsam tak leh friendly takin kan sawi dawn a ni.

A awlsam zawngin Blastocyst chu eng nge ni?

Ngaihtuah teh, hmeichhe hrisel egg chu mipa hrisel tak sperm hmanga fertilized a nih hnuah, cell lo piang hmasa ber chu zygote an ti a. Chu cell chu rang takin a inthen tan ta a ni. Pakhat chu pahnih a lo ni a, pahnih chu pali a lo ni a, chutiang chuan ball ang chi thil te tak te, blastocyst .

A awlsam zawngin, blastocyst hi embryo lo piang hmasa ber a ni . Sperm-in egg a fertilize hnu ni nga atanga ni ruk vel a lo awm thin. Hei hi naupai laia thil pawimawh tak a ni. Hei hi heng cell te hi an fuse a, uterus wall-a an inzawm hian a ni. Hei hi implantation kan ti a.

He Blastocyst stage hi IVF (In Vitro Fertilization) -ah hian a pawimawh hle a, a chhan chu doctor-te chuan Blastocyst hrisel ber leh hmasawn ber thlangin nu nausen pum chhungah an dah thei a ni. Hei hian naupai hlawhtling theihna a tipung a ni.

Engtin nge nau pai dan hi a lo awm?

Blastocyst pawimawhna chiang taka hriat theih nan nausen naupai dan zawng zawng hi tlem tal ngaihtuah a \angkai hle. He zinkawng mak tak hi step khat hnu step khata a kal zel dan hi han thlir ila.

1. Ovulation: A tlangpuiin hmeichhia thla tin thlasik tan atanga ni 14 vel hnuah a ovary pakhat atangin egg puitling (ovum) a chhuak thin. He egg hi fallopian tube hnuaiah a kal a, sperm hmanga fertilization a nghak thin.

2. Fertilization: Hetih hun chhung hian mipat hmeichhiatna a awm chuan sperm pakhat hian fallopian tube chhunga egg chu a tawk thei a, chu chu a inzawm khawm thei a ni. Hei hi fertilization kan tih chu a ni.

3. Zygote siam dan: Egg fertilized chu ‘zygote’ kan ti a. Hei hi nu leh pa pahnih gene inzawmkhawmtu single cell hmasa ber a ni.

4. Blastocyst Stage thlenga zinkawng:He zygote hi fallopian tube atanga ni thum atanga ni nga vel chhung chu nausen pum chhungah a kal thin. Chutah chuan a thu mai mai lo va, a inthen darh zel a ni. Cell pahnih, pali, pariat... a inthen chak hle a, ball te tak te, cell za tam tak awmna leh a chhungah cavity a lo awm ta a ni. Chu chu Blastocyst kan tih chu a ni.

5. Implantation: Nausen pum a thlen hnuah chuan blastocyst chu ni engemaw zat chu chutah chuan a awm a, nausen pum chhung bang (endometrium)-ah a inzawm tlat a ni. Hei hi ‘implantation’ kan tih chu a ni.

6. Embryo leh Fetus: Nausen pum chhunga dah a nih hnuah heng cell te hi an inthen chhunzawm zel a, an thang lian zel a, embryo an lo ni ta a ni. Kar 9 vel hnuah he embryo hi a lo thanglian lehzual a, nausen (fetus) a lo ni ta a, chu chu kan hriat angin nausen pum pui a ni.

Blastocyst hian eng hna nge a thawh? Engvangin nge hei hi a pawimawh em em?

Blastocyst stage hi embryonic leh fetal development-a stage pawimawh tak leh pumpelh theih loh a ni. A chhan awlsam tak chu blastocyst hian uterine wall-ah a implant tha lo a nih chuan naupai a awm dawn lo tihna a ni.

He implantation hi thilmak tak hmanga tih a ni. Kan taksaa hormone awmte nghawng hnuaiah hian blastocyst hian "hatching" tih process a paltlang a. Egg atanga chick a chhuah ang bawkin blastocyst hian a pawn lam membrane te tak te (zona pellucida) chu a tichhia a ni. Hei hi nausen pum chhunga a luh atanga ni khat emaw ni thum emaw chhungin a thleng thin.

Tichuan hna tak tak chu a thleng ta a ni. Blastocyst chhungah hian cell layer hnih a awm a.

• Trophoblast: Heng cell te hi uterine wall-a inzawm hmasa ber an ni. Chu chu sticky protein (L-selectin) siamin an ti a, chu chu glue ang mai a ni. Heng cell te hian a hnuah placenta an siam thin . Placenta hi taksa peng pawimawh tak a ni a, naute tan oxygen leh nutrients a pe a, naute atanga bawlhhlawh paih chhuaktu a ni.
• Inner cell mass: He cell mass hi a hnuah nausen chhungah a lo thang lian ang .

Placenta chhunga cell thenkhat chu an inzawm khawm a, amniotic sac an siam a, chu chu naute hual veltu tui venna bag a ni.

Blastocyst dah luh a nih chuan eng chhinchhiahna nge awm?

Mi tam zawk chuan tun dinhmunah hian symptom engmah an nei lo. Mahse mi thenkhat, hmun thuma ṭhena hmun khat vel chuan natna lan chhuahna engemaw zat an nei thei. Hengte hi i naupai tih hriattirna hmasa ber a ni mai thei. Mahse mi zawng zawng hian heng symptoms hi kan nei vek lo a, heng symptoms neih hian naupai tihna a ni lo. Chuvangin doctor nena inbiakna neih hi a tha ber fo.

Blastocyst hian nau a pai thei em?

Hei hi thupui sensitive tak sawi tur a ni a, mahse hriat a pawimawh hle. Ni e, blastocyst hian nau a pai thei a, hlawhtling takin a implant thei lo bawk. Dik tak chuan nau pai hma lutuk zinga 75% vel chu blastocyst hlawhtling taka a implant loh vang a ni.

Engvangin nge hetiang hi a lo awm?

Hei hi a chhan ber chu chromosomal abnormalities vang a ni.Blastocyst chhunga cell te an inthen hian a chang chuan chromosomes ah harsatna a awm thei bawk. Entîr nân, chromosome dang a awm thei a, chromosome bo a awm thei a, chromosome ṭhenkhat a chhe thei bawk.

Hetianga implantation a hlawhchham chuan naupai hi a intan thei a, mahse a hma lutuk (kar 5 vel) a tawp thei. Hei hi "chemical pregnancy" kan tih chu a ni. I period a tlai emaw, naupai test i neih loh chuan hetiang hi a thleng tih pawh i hre lo mai thei.

A tlem hle a, chromosomal abnormality nei blastocyst chu a implant thei a, naupai chu a kal zel thei bawk. Chutiang hunah chuan naute hian Down syndrome, Klinefelter syndrome, Turner syndrome ang chi natna a neih theihna a awm.

IVF neih chhung hian heng chromosomal problems te hi hriat lawk theih dan a awm em?

Ni e, tunlai damdawi lam hmasawnna avang hian hei hi chinfel dan tur a awm ta. IVF enkawlnaah hian blastocyst chu nausen pum chhunga dah a nih hmain a atang hian cell tlemte lakchhuah a ni a, chromosomal problems a awm leh awm loh test theih a ni.

He test hi Preimplantation Genetic Testing (PGT) tih a ni.

He test hmang hian doctor-te chuan chromosomally healthy blastocyst chu uterus-a dah tur an thlang thei a ni. Chuvangin,

• Naupai hlawhtling tak neih theihna a sang hle.
• Nau pai hmaa awm theihna a tlem phah.
• Chromosomal abnormalities nei fa neih theihna a ti tlem thei a ni.

Naupai pianphung anga nau pai tan chuan heng test chi hrang hrangte hi naupai kar 9 emaw kar 10 emaw hnuah chauh tih theih a ni.

Chromosomal abnormalities awm theihna hi a tlahniam thei ang em?

Vanduaithlak takin risk factor thenkhat chu kan thunun theih loh a ni.

• Kum 35 aia upa a nih vang.
• Chhungkaw history-a chromosomal disorder nei tawh.
• Tun hmaa nau pai tawh emaw, naute chromosomal problem nei tawh emaw.

Heng risk factors te hi i neih chuan fa neih i tum dawnin i doctor leh genetic counselor te nena inbiakna neih a pawimawh hle.

Amaherawhchu, kan thunun theih thil a awm. Naupai hma leh naupai hnua nunphung hrisel kan zawm hian nausen tana chhiatna thlen theihna kan ti tlem thei a ni.

• Thil tha lo (toxic substances) nena inhnim hnawih loh tur.
• Ruihhlo leh zu hman hi pumpelh vek tur a ni.
• Ei leh in inthlau tak ei rawh.
• Doctor thurawn angin vitamin mamawh te ei thin ang che.

Blastocyst hi naupai hrisel tak neihna atana bul tanna pawimawh tak a ni. Hlawhtling taka a lo thanglian lo a, nausen pum chhungah a implant loh chuan naupai a awm lovang. Naupai tirh lamah light spotting emaw, natna emaw i neih chuan hlauthawng lo la, ngaihsak lo la, doctor pan nghal la, thurawn la rawh. A enfiah thei che a, engkim a kal tha em tih a enfiah thei bawk.