I chhungkuaa mi tu emaw, i nu duh tak, i pa, i pi emaw, i pi emaw, Alzheimer natna vei an ni mai thei. A nih loh leh he natna chungchang hi hriat belh i duh a ni mai thei. Alzheimer’s hi dementia chi khat a ni ber a, ngaihtuahna thiamna, hriatrengna, harsatna chinfel thiamna leh tawng thiamna te chu zawi zawiin a bo vek a ni. Hei hian nitin hna thawh a harsat phah thei a ni.
Alzheimer natna vei theihna tur risk factor lian ber chu kum upa lam hi a ni. Tuna damdawi hman mek hian eng emaw chen chu natna lan chhuah dan a thunun theih laiin, natna hi a titawp vek thei lo. Chuvang chuan zirchiangtute chuan natna zual zel tur tikhawtlai thei tur damdawi thar an zawng mek a ni. Vawiin hian heng thluak tichaktu enkawlna pahnih kan sawi dawn a ni. A awlsam zawngin sawi ila, heng enkawlnate hian electrical emaw magnetic wave emaw hmangin thluak hmun thenkhat hnathawh chu "on" emaw "off" emaw a ni.
rTMS (Repetitive Transcranial Magnetic Stimulation) tih hi eng nge ni?
Hei hi Alzheimer natna vei enkawlna thar endik mek zinga mi a ni. Thluak hmun bik pakhat tichak turin pawn lam magnet hman a ni a, operation ngai lovin. "Repetitive" an ti a, a chhan chu kar khatah ni nga, nitin kar li atanga kar ruk chhung enkawl a nih vang a ni.
Chair pangngaiah i thu ang tih han ngaihtuah teh. Doctor chuan i lu chungah electromagnetic coil a dah a. Activate a nih chuan tukanawak te tak te hian second engemaw zat chhung "click" "click" sound hmangin i hmai a rawn deng ang maiin a lang. Anesthesia (lu tiharh) a ngai lo. Surgery a nih loh avangin doctor office emaw clinic emaw-ah pawh tih theih a ni.
Alzheimer vei te zingah rTMS hian engtin nge hna a thawh tak tak tih hi 100% in a chiang lo. Hetianga thluak tihchak hian hriatrengna leh ngaihtuahna nena inzawm thluak hnathawh a ti chak emaw, a tikhawtlai emaw thei niin zirchiangtute chuan an ngai.
Hei hi engtiang chiahin nge a hlawhtlin?
rTMS enkawlna hlawhtlinna hi thil engemaw zatah a innghat a ni. Entirnan, low-frequency stimulation hian thluak hnathawh a ti tlem tih hmuhchhuah a ni a, high-frequency stimulation hian a tipung tih hmuhchhuah a ni bawk. Tin, enkawlnain a tum thluak hmun leh damdawi dang eng pawh damloin a ei lai hian a result a nghawng thei bawk.
A tlangpuiin, high-frequency stimulation hi dementia na lo zawk nei te aiin dementia na zawk nei te tan a hlawk zawk tih hmuhchhuah a ni. A chang chuan, enkawl zawh veleh result tha tak tak hmuh tur a awm nghal a, mahse mi thenkhat tan chuan result hmuh nan kar 6 vel a ngai thei. Heng hamthatna te hi thla 3 emaw a aia rei emaw a awm thei.
A chang chuan he rTMS enkawlna hi thluak tan cognitive training chi khat a ni.A thawh ho a ni. Chu chu thluak hnathawh thatna tur thil chi hrang hrang leh exercise hrang hrang pek hi a ni. Heng pahnih hi tih dun a nih chuan result tha zawk a awm a, a bik takin Alzheimer’s vei na lo leh natna vei te tan chuan a tha zawk a ni.
Pawimawh tak chu Alzheimer vei zinga a chanve vel chuan lungngaihna an vei a ni. rTMS hi FDA-in a pawmpui, depression enkawlna a ni. Chuvangin, Alzheimer vei te tana rTMS enkawlna hlawkna chu natna tak tak vang nge, a kaihhnawih lungngaihna vang nge tih hi hriat chian a harsa hle.
| rTMS enkawlna avanga side effect leh complication awm thei te | Hrilhfiahna |
|---|---|
| Side effect awm fo thin | Magnet awmna hmuna nuam lo, hmui, lu vun emaw hmai emaw a tingling, lu na leh luak chhuak a awm thei. |
| Side effect na tak tak mahse a awm lo | Seizures hi a awm tlem thei hle. Hun rei tak chhunga a nghawng dan tur hi hriat tur a la tam lo hle. |
| Harsatna awm thei te | Researcher thenkhat sawi dan chuan high-frequency stimulation hian Alzheimer natna a tizual tak tak thei tih ngaihtuahna a awm. Hemi chungchangah hian zirchianna neih belh a ngai a ni. |
Deep Brain Stimulation (DBS) hi eng nge ni?
rTMS ang lo takin DBS hi invasive treatment a ni a, thluak operation a ngai a ni. Hei hi hmasawnna lian tak a ni. He surgery-ah hian i thluaka electrode pahnih dah a ni. Pacemaker ang bawkin heng electrode te control tu generator te tak te pahnih chu i rilru vun hnuaiah dah a ni.
Surgery hma hian i lu MRI scan an nei ang. Surgery neih chhung hian i harh chhuak ang. Lungngai suh, i lu chu a numbed (local anesthetic) a nih avangin natna engmah i hre lo ang. Thluak hian natna a hriat loh avangin doctor chuan MRI images hmangin electrode te chu hmun dik takah a dah thei a ni. Tichuan, general anesthesia hnuaiah dah i ni ang a, i thluaka electrode-te nena inzawm generator leh wire te chu i rilruah dah a ni ang. Surgery zawhah he device hian i thluak chu a tichak chhunzawm zel ang.
DBS therapy hi Parkinson natna lanchhuahna, khur leh rigidity te enkawlna atan hman hmasak ber a ni. Damlo pakhat, thau lutuk avanga DBS hmanga enkawlna dawngtu pakhatin a hriatrengna lama hmasawnna a lantir hnuah chauh zirchiangtute chuan Alzheimer natna atan pawh hman theih a nih leh nih loh an chhui tan ta a ni.
Hei hi engtiang chiahin nge a hlawhtlin?
Zirchianna hmasa berah chuan DBS hi enkawlna beisei awm tak a ni tih a lang. Mahse, a hlawhtlinna chu natna stage leh enkawl dan tur (thluak target area, stimulation chakna) ah a innghat a ni.
A tlangpuiin DBS enkawlna hi natna hmasa ber (early-stage Alzheimer’s)-a hman a nih chuan a hlawk ber . Kum 65 hnu lama hmuhchhuah (late-onset) te hian hlawkna an hmu thei a, chu chu natna hian a zual zelna a tikhawtlai thei tihna a ni. Mahse mak tak maiin kum 65 (early-onset) hmaa natna hmuhchhuah tawhte chuan he enkawlna hian hlawkna lian tham an hmu lo.
| DBS enkawlna avanga side effect leh complication awm thei te | |
|---|---|
| Surgery nena inzawm harsatna awm thei | |
| Surgery hian thisen a chhuah thei a, natna hrik a thlen thei a, rilru chhunga hardware awmte pawh a thawk tha lo thei bawk. | |
| Stimulation nena inzawm side effects te | |
| |
| Side effect dang awm thei | |
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Side effect thenkhat (lu na, luak chhuak, luak chhuak) chu hun kal zelah a reh mai ang a, mahse DBS hi damdawi hlauhawm tak a ni tih hriat reng a pawimawh.
Take-Home Thuchah a ni
- Alzheimer's hi natna zual zel a ni. Tuna damdawi hman mekte hian natna lan chhuah dan chu thunun thei mah se, natna a tidam thei lo.
- rTMS hi non-surgical, low-risk brain stimulation technique a ni a, natna hmasa berte tan chuan hlawkna engemaw chen a nei thei a, mahse research phase-ah a la awm reng a ni.
- DBS hi enkawlna pawi tak, risky tak a ni a, thluak zai a ngai a ni. Natna tan tirh lamah pawh mi thenkhat tan a \angkai thei a, mahse hman lar a la ni lo.
- Heng enkawlna pahnihte hi Alzheimer natna tan experimental a la ni a, damdawi pek dan pangngai a ni lo.
- A pawimawh ber chu i chhungkuaa mi tu emaw hian Alzheimer natna a vei a nih chuan eng enkawlna tur pawh i rel hmain doctor nen fimkhur takin inbia la, damlo dinhmun nena inmil ber chu hrethiam rawh.
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