Mi tam tak chuan ‘Breast Cancer ’ tih thumal kan hriat hian kan hlau thin a ni lawm ni? Mahse hei hi natna chi khat chauh a ni lo, chi hrang hrang a awm tih i hria em? Eng ang cancer nge i neih tih chiang taka hriat hi eng enkawlna nge i dawn dawn tih hriat a pawimawh hle. Chuvangin vawiin hian he thu hi awlsam tak leh friendly takin i sawi dawn nia. Chûng thilte hriat chu i tân chakna nasa tak a ni ang.
Cancer hi a bul tanna hmun a zirin classification
Doctor-te’n hnute cancer an sawi dan pakhat chu taksaa khawi atanga lo intan nge tih leh a darh tawh em tih hi a ni.
A awlsam zawngin, hnute cancer tam zawk hi carcinoma an tih chi a ni. Chumi awmzia chu hnute chhung leh taksa peng dangte line-a awm tissue-ah an intan tihna a ni. Chung zinga a tam zawk chu adenocarcinoma an tih subtype-ah an tla a ni. Hengte hi hnute hnute kengtu duct emaw, hnute siamtu glands (lobules) atanga tan cancer te an ni.
Ductal Carcinoma a awm thin
Hei hi hnute cancer chi khat a ni ber. Pang lian pahnih a nei bawk.
1. Ductal Carcinoma In Situ (DCIS): Hei hi hnute cancer vei hmasa ber a ni . 'In Situ' tih thumal hi "a awmna hmun" tihna a ni. Chumi awmzia chu cancer cell te hi bawnghnute kawng chhungah chauh an la awm tihna a ni. Pawnah an la darh lo. Hetiang chi hi hnute cancer hmuhchhuah thar 5 zinga 1 vel a ni. A tha ber chu he chi hi a dam vek tawh mai.
2. Invasive Ductal Carcinoma (IDC): Hei hi hnute cancer chi khat zingah chuan a tam ber a ni . Hnute cancer hmuhchhuah zawng zawng zinga 80% vel a ni. 'Invasive' tih awmzia chu "aggressive" tihna a ni. Chumi awmzia chu cancer cell te chu bawnghnute kawng pawnah leh a chhehvel tissue-ah an darh tawh tihna a ni. Hetiang IDC hi subtype engemaw zat a awm a. An buaithlak deuh nachungin, awlsam takin han thlir ila.
| IDC Subtype a ni | A sawifiahna awlsam tak |
|---|---|
| Medullary Carcinoma natna a ni | A hming hi thluaka soft tissue ang maia a lan vang a ni. A tlem hle (5% aia tlem) a ni. |
| Mucinous Carcinoma natna a ni | Cancer cell chhehvelah hian mucus ang chi (mucin) a tam hle. Hei pawh hi a tlem hle (2% aia tlem). |
| Tubular Carcinoma a awm thin | Cancer cells hian an chhungah tube ang chi structure an nei a. Chûngte chu clump-in an ṭhang lian fo a, enkawlnaah pawh an chhân lêt ṭha hle. |
| Papillary Carcinoma a awm a ni | Cancer cell-te hi kut zungtang ang maia sang (papules) a awm a. Hmeichhe kum upa zawkah an tam hle. |
| Cribriform Carcinoma natna a ni | He cancer hmuh tur awm lo cell inkarah hian tlang ang maia awm a awm a. |
Lobular Carcinoma a awm thin
Hetiang chiah hian hnute hnute siamtu glands (lobules) lining-ah hian cell pangngai lo tak tak a lo thang lian a .
- Invasive Lobular Carcinoma (ILC): Hei hi hnute cancer chi hnihna a ni. Hetiang cancer chi hi hnute atanga intan a, a chhehvel tissue-ah a darh thin. Chumi hnuah taksa peng dang, lymph node-ah te a darh thei a ni.
- Lobular Carcinoma in Situ (LCIS): He hming hian hlauthawng suh. Doctor-te chuan LCIS hi cancer-ah an ngai tak tak lo a, a chhan chu hnute pawnah a darh loh vang a ni. Mahse, LCIS neih hian nakin lawkah hnute cancer vei theihna chance tlem a sang zawk tihna a ni.
Breast cancer chi dang hmuh tur awm lo
Hengte hi a tam vak lova, mahse hriat hlawh tak a ni.
- Inflammatory breast cancer: Hei hi a tlem hle (5% aia tlem) leh na tak chi a ni. A natna lan chhuah dan chu a dang nen a danglam hle. Cancer cells hian hnute chhunga lymphatic vessels te chu a block thin. Hei hian hnute a ti hring a, a sen a, vun a ti thim bawk . A châng chuan hnute vun hian orange peel angin a lang thei bawk. Hetiang chi hi a darh chak thei hle.
- Phyllodes Tumor: Hengte hi hnute connective tissue-a lo awm, tumor awm lo tak tak an ni. An zinga 4 zinga 1 chauh cancer vei an ni. A bak zawng chu benign tumor an ni.
- Angiosarcoma: He cancer hi thisen kalna kawng leh lymph kawng lining-ah a lo awm a. Kum 70 chunglam ah a tam ber.
- Paget natna : Hei pawh hi a tlem hle. Nipple leh a chhehvel (areola)-a lo awm cancer a ni. Nipple vun chu a hring thei a, a sen thei a, a hring thei bawk . Paget natna vei tam tak hian cancer chi khat DCIS emaw IDC emaw an nei bawk.
- Metastatic Breast Cancer: ‘Metastatic’ tih awmzia chu hnute pawn lam atanga taksa peng dangah a darh tawh tihna a ni. Doctor-te chuan hei hi "advanced" emaw "stage 4" emaw an ti bawk. A darh tam ber chu thin, thluak, ruh emaw, lung emaw-ah a ni.
A pawimawh ber chu, cancer chi hrang hrang ni se, a hmaa hmuhchhuah leh enkawl dan dik a nih chuan a dam theihna chance a sang zawk hle.
Cancer hi gene leh hormone hrang hranga thliar hrang
Breast cancer i vei tih i hriat hnuah i doctor chuan cancer cell-te chu special test engemaw zat a nei ang a, hormone estrogen emaw progesterone emaw , emaw, gene bik a awm em tih emaw chuan cancer thanna a nghawng em tih a enfiah ang.
Heng test atang hian doctor chuan i tan a tha ber, targeted treatment a thlang thin.
- HER2-positive: Hnute cancer 5 zinga 1 vel hian protein pakhat `HER2` (Human Epidermal Growth Factor Receptor 2) an nei a. He protein hian cancer cell te chu a ti thang lian thei a ni. HER2-positive cancer te hi a na zawk thei. Mahse he protein hi targeted therapies a awm a, chu chuan enkawl a awlsam phah hle.
- Hormone Receptor-positive emaw negative emaw: Cancer cell thenkhat chuan an chung lamah hmun bik (receptor) an nei a, chu chu hormone in a inzawm theihna tur a ni. Cell chu kawngkhar angin ngaihtuah la, heng receptor te hi a chhunga keyhole ang mai an ni.
- ER-positive: Cancer cell hian hormone estrogen nena inzawm thei receptor an nei a.
- PR-positive: Cancer cell hian hormone progesterone nena inzawm thei receptor an nei a.
- Hormone receptor-positive tih awmzia chu heng pahnih zinga pakhat emaw, pahnih emaw a awm tihna a ni. Hormone hian heng cancer chi hrang hrangte hi a tipung thei a, chuvang chuan hormone-blocking drugs (hormone therapy) hmangin hlawhtling takin enkawl theih a ni.
- Hormone receptor-negative tih awmzia chu heng receptor pahnih hi a awm lo tihna a ni.
- Triple-negative: Hetiang chi hi 15% vel a ni. A hming ang bawkin heng cancer cell te hian estrogen receptor (ETRs) an nei a., progesterone receptor (PR) leh HER2 te chu a bo vek a ni. Chuvangin hormonal therapy emaw HER2-targeted therapy emaw hmanga enkawl theih a ni lo. Hei hian enkawlna a ti harsa deuh thei a, mahse enkawlna dang a awm a, chu chu chemotherapy te hi a ni.
Cancer chi hrang hrang i neih i hriat hnuah, i doctor nen i dam theihna chance a nghawng dan leh enkawlna tha ber berte chu zalen takin sawipui rawh. Zawhna zawng zawng zawh hlau suh.
Take-Home Thuchah a ni
- Hnute cancer hi natna pakhat chauh a ni lova, chi hrang hrang a awm a.
- Cancer i neih chi hi hnute chhunga khawi atanga lo intan nge (milk ducts/glands), a darh leh darh loh, leh hormone thenkhat (ER, PR) emaw protein (HER2) emaw in a nghawng danah a innghat a ni.
- A chi thenkhat, DCIS ang chi te hian damna rate an nei sang hle a, Inflammatory Breast Cancer ang chi erawh chu a na zawk thei.
- I cancer hormonal leh genetic (receptor) status hriat hi enkawlna tha ber leh targeted ber i pek theih nan a pawimawh hle.
- I natna hmuhchhuah dan, cancer chi hrang hrang, leh enkawl dan tur chungchanga zawhna i neih apiang chu i doctor nen sawiho hreh ngai suh. Hriatchhuah hi indona hnehna chanve a ni.
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