Giant Cell Tumor (GCT) hi i hre tawh em? I sawi dawn nia!

I kutah, a bîk takin i khup, i hip, i kekawrte, a nih loh leh i kutphahah natna dull, swelling tlem, emaw lump i nei ngai em? Chutiang a nih chuan tlem tal ngaihtuah a tha. A chhan chu vawiin a kan sawi tur dinhmun ‘Giant Cell Tumor (GCT)’ tih chhinchhiahna a nih theih avangin. Ngaihtuah buai suh, hemi chungchang hi chipchiar takin kan sawi dawn a ni.

Giant Cell Tumor (GCT) hi eng nge ni tak tak?

A awlsam zawngin sawi ila, ``Giant Cell Tumor (GCT)`` hi cancer ni lo (leh a tam zawkah chuan benign) tumor a ni . I taksa ruh sei tak tawp lamah an lo awm tlangpui. A bik takin, i thigh bone hnuai lam ``femur`` emaw i shin bone chunglam ``tibia`` emaw, khup vel a awm emaw ah an awm tlangpui. Mahse, hip, shoulder, wrist, leh tailbone ang hmunah te pawh an lo piang thei bawk. Chungte chu ``Osteoclastomas`` an ti bawk.

Hetiang dinhmun `(GCT)` an tih hi a takah chuan a tlem hle . Mi sang za zelah mi pakhat atanga pahnih vel ah a awm thin. Mahse, ruh atanga tan cancer nei lo tumor zingah chuan `(GCT)` hi case zawng zawng zinga 15% leh 21% inkar a ni.

A chang chuan heng giant cell tumor te hi ruh ah ni lovin, ruh chhehvel soft tissue ah te an lo awm thin. Tichuan ``Tenosynovial giant cell tumors'' an ti ta a ni.

A pawimawh ber chu heng `(Giant Cell Tumors)` te hi cancer ni lo mahse, an thang chak thei a, an chhehvel tissue hrisel tak tak te pawh an tichhe thei a ni . Tin, enkawl hnuah pawh `(recurring)` chance an nei sang hle bawk. Chuvangin hetiang tumor chhinchhiahna i hmuh chuan a rang thei ang bera doctor pan a pawimawh.

Hei hi eng symptoms nge ni? Hengte pawh hi i nei em tih en rawh...

Giant cell tumor (GCT) chhinchhiahna ber leh langsar ber chu natna hi a ni . A tir lamah chuan natna hi a na lo thei hle nachungin, tumor a lo lian chhoh zel chuan a na zual zel a ni. Ngaihtuah teh, zing khat chu i harh a, i khup bulah natna tlem i nei a. A tirah chuan i ngaihsak lo. Mahse rei vak lo hnuah a na zual zel a, i khawih chuan zung te tak te ang maiin a awm thin. Chutah chuan i hlauthawng deuh thin a ni lawm ni?

Symptom dang engemaw zat a awm bawk:

• Kut chhunga hnim hring emaw, hliam emaw hriat theih chu chu hmunah chuan a lang a.
• Tumor awmna hmunah hian ruh chu a kal tha thei lo tihna a ni.
• Joint pain , a bik takin joint tihchet hian.
• Vung .
• Tumor hian ruh a tichak lo thei a , ruh a tikehsawm thei bawk .

Heng symptoms pakhat emaw a aia tam emaw i neih chuan doctor rawn la.

Engvangin nge hetiang thil hi a lo thlen? Eng nge a chhan?

Dik tak chuan damdawi lam zirchiangtute chuan giant cell tumor thlentu hi eng nge ni tih chiang takin an la hre lo. Mahse, he natna vei thenkhat chuan an gene-ah hian inthlak danglamna (mutations) engemaw zat an nei tih hmuhchhuah a ni. Mahse, tunah chuan hei hi rochun thil a ni lo tih rin a ni a, i chhehvel emaw, i nunphung emaw avanga lo awm a ni lo .

Risk factors a awm em?

Ni e, dinhmun thenkhatah chuan he `(GCT)` lo awm theihna chance hi tlem a sang thei a ni:

• `(Hyperparathyroidism)` (parathyroid hormone i siam tam lutuk) i neih chuan i taksa hmun engemaw zatah `(GCT)` a lo awm thei a ni.
• A tlem hle a, ruh natna ``Paget's disease of the bone'' an tih nei te pawhin heng giant cell tumor te hi an nei thei bawk.

Hei hi a hlauhawm thei ang em? Eng harsatna nge a awm?

Heng tumor te hi cancer ni lo mahse, a tlem hle, chu chu a tlem hle a ni, heng giant cell tumor te hi lungah ``a darh`` thei a ni . Amaherawhchu, cancer a darh ang a ni lo va, hetiang hian a darh a nih pawhin a tlangpuiin nunna atana hlauhawm a ni lo.

Chu aia tlem zawk chu GCT vei zinga 4% vel ah chuan heng tumor te hi cancer (malignant) a lo ni thei a ni . Chuvangin, i doctor chuan i dinhmun chu a enfiah fo ang a, tumor-ah hian danglamna hlauhawm tak a awm leh awm loh a en reng ang. Hei vang hian doctor pan fo a, thurawn lak a pawimawh hle.

Doctor-te hian engtin nge hei hi an hmuh?

Giant cell tumor (GCT) i neih leh neih loh finfiah nan biopsy an ti thin. Hei hian tumor atanga tissue sample te tak te lak a, microscope hmanga enfiah a huam a ni. He test hi pathologist, tissue lama tui tak doctor-in a ti thin. Amah chuan cell te hi "giant cells" an nih leh nih loh a enfiah ang a, GCT ang chi mizia an nei em tih a enfiah ang.

Chu bakah, i taksa chhunga tumor awm chu enfiah nan heng ang imaging test te hi tih theih a ni bawk:

• X-ray : Ruh dinhmun enfiah thin.
• CT scan : Tumor lian leh te chipchiar takin en rawh.
• MRI : Tissue nem, ruhro, etc. te a enfiah thin.
• Bone scans : Ruh hmun dangah harsatna a awm leh awm loh enfiah thin ang che.
• PET scans : Tumor chu cancer-ah a chantir tih hriatna a awm em tih enfiah nan.

Heng test zawng zawng hi i dinhmun hriatthiamna famkim neih theihna tur leh enkawlna tha ber hriat theihna tura tih a ni.

Okay, tunah chuan hei hi eng enkawlna nge ni?

Giant cell tumor hi operation hmanga enkawl a ni fo thin . Doctor chuan ruh (curettage) atanga tumor chu a la chhuak thin. Tichuan, ruh (bone graft) chu hmun ruak hmunah dah a ni.Chu ruh chu grafting (hmun dang atanga ruh chi khat emaw, thil siam emaw atanga lak chhuah) hmangin a tichak a ni. A chang chuan tumor hi a lian hle a nih chuan tumor awmna ruh zawng zawng chu lak chhuah a ngai mai thei. Chutiang a nih chuan a hmunah artificial joint emaw bone ``prosthesis`` emaw dah theih a ni.

Mahse, operation hmanga tumor chu a chhuak kim thei lo emaw, surgery a risky a nih chuan non-surgical treatment a awm a ni. Chung zingah chuan:

• Denosumab (Denosumab - Xgeva®) : Hei hi damdawi chi khat, monoclonal antibody an tih a ni. Tumor chu a ti tlem a, a chhehvel ruh a tichak bawk.
• Embolization : Hei hian tumor-a thisen petu thisen kalna kawngte chu a block a ni. Hei hian tumor chu thisen a hloh a, zawi zawiin a thi ta a ni.
• Ablation therapy : Hei hian microwave energy ang chi hmangin tumor chu a tichhia a ni.
• Radiation therapy : Hei hian high-energy X-ray hmangin tumor chu a ti tlem a, cell a tichhia a ni.

I doctor chuan eng enkawlna nge i tan a tha ber tih a rel ang.

Enkawl hnua dam leh theih nan eng chen nge a duh?

I dam leh theih hun chhung chu i enkawlnaah a innghat a ni. Surgery i neih chuan hliam a dam chhung hian kar engemaw zat bandage i vuah a ngai dawn a ni. Chutih lai chuan kekawrte pawh i hman a ngai mai thei bawk. Prosthetic device i neih chuan i hman thiam theih nan physical therapist nen thawhhona tha tak i neih a ngai dawn a ni.

I doctor chuan heng zawng zawng hi a hrilhfiah vek ang che, chuvang chuan ngaihtuah tur a awm lo.

Hetiang thil thleng tur hi ven dan tur a awm lo em ni? Hriat lawk hian eng hlawkna nge a neih?

Giant cell tumor lo awm chhan dik tak hriat a nih loh avangin tunah hian a lo awm lohna tura ven theih a ni lo . Mahse, i tih theih ṭha ber chu i natna lan chhuah dan i hriat veleh damdawi lam thurawn lak hi a ni . I ruh emaw, i ruh emaw pakhatah na, a hring emaw, a hring emaw i hmuh chuan ngaihthah suh la, doctor pan nghal rawh. `(GCT)` ang tumor hi hmuh hmasak a nih chuan enkawl a awlsam zawk a , harsatna a awm tlem zawk bawk.

A theih chuan ruh nena inzawm cancer lam thiam doctor, orthopaedic oncologist .

Chuti a nih chuan engtin nge he dinhmun hi i nunpui? Doctor i hmuh fo a ngai em?

Giant cell tumor hi nunna atana hlauhawm a ni tlem hle. Mahse, i ruh leh a chhehvel tissue te an tichhe thei a, chuvang chuan enkawl hmasak a pawimawh hle.

Thu lawmawm tak chu tumor peng zawng zawng surgery hmanga lak chhuah vek a nih chuan he natna hi a dam vek thei a ni. Mahse, GCT hi tumor chi khat, rilru na tak a ni a, a lo thang leh thei bawk .

Enkawlna i neih zawh chuan i doctor chuan follow-up appointment neih leh neih loh a enfiah fo ang che . Hei hi tumor chu a lo let leh tawh em tih enfiah nan a ni. A tam zawkah chuan heng tumor te hi operation hnu kum hnih atanga kum nga chhungin an lo lang leh thin. Mahse, i dam chhung zawngin check-up neih fo a ngai mai thei. I doctor chuan heng check-up te hi eng chen nge i lo kal tur tih a hrilh ang che.

Engtikah nge doctor i hmuh leh a ngaih?

I giant cell tumor a lo kir leh tih hriatna i neih chuan doctor pan nghal rawh. Ruh emaw ruh emaw thar na emaw, a hring emaw a awm chuan fimkhur rawh. I doctor-in a check fo che a nih pawhin, danglamna i hmuh chuan i appointment leh tur nghak lovin i doctor biak nghal mai a tha ber.

Doctor hnenah eng nge zawh i duh ang?

Doctor i hmuh hian heng zawhnate hi zawh a tha ang:

• He tumor hi engtiang chiahin nge a aggressive ?
• Eng enkawlna kawng nge ka neih?
• Heng enkawlna pakhat zel hian eng hlawkna leh hlauhawmna nge a neih?
• He giant cell tumor hi enkawl hnuah a lo lang leh theihna chance chu engzat nge ni?
• Follow-up appointment atan engzat nge ka lo kal a ngai dawn ?

Hêng zawhnate chhânna i hriat hian i dinhmun chu i hrethiam zâwk ang a, enkawlna i hmachhawn pawh a awlsam phah ang.

Chuti a nih chuan, he thawnthu atang hian eng thil nge kan hriat reng tur pawimawh ber?

Giant cell tumor (GCT) chu "benign" a nih vang mai mai chuan harsatna a thlen dawn lo tihna a ni lo. Enkawl loh chuan heng GCT te hian i ruh te chu nasa takin a tichhe thei a ni.

A tha ber chu operation hmanga tihbo theih a ni a, tumor hnuhma zawng zawng chu paih vek a ni. Mahse, heng `(GCT)` te hi an rilru a na deuh a, an lo thang leh thei bawk. Chuvang chuan i doctor chuan enkawl hnuah uluk takin a lo vil reng ang che. Tumor chu a la te laiin lakchhuah chuan ruhte hun rei tak a tihchhiat loh nan a veng thei a ni.

Chuvangin, heng symptoms te hi i neih chuan doctor pan hreh suh la, thurawn la rawh. Inenkawl hmasak hi nun hrisel neihna kawng tha ber a ni!

` Giant Cell Tumor, GCT, osteoclastoma, benign tumor, ruh natna, ruh na, tumor enkawl