Kan cholesterol kan check hian "cholesterol tha" (HDL) leh "cholesterol tha lo" (LDL) chauh kan en tlangpui a, a dik em? Mahse, cholesterol chi pawimawh tak, mi tam takin an sawi loh, mahse a inkarah thup tlat a awm tih i hria em? Hei hi Lipoprotein(a) a ni a, a tawi zawngin Lp(a) a ni. Hemi chungchanga thil danglam bik chu kan genes-in a ruat a, chu chu kan ei leh in emaw, kan exercise emaw aiin, thlah khat atanga thlah dangah a kal zel tihna a ni. Mi hrisel tak i ni thei a, mahse i Lp(a) level erawh a sang hle mai thei.
Lipoprotein(a) hi eng nge ni tak tak?
A awlsam zawngin sawi ila, hei hi kan thisena cholesterol awmna particle a ni bawk. Mahse he thila buaina chu a level hi kan genes-in a hril tam ber a ni. Chumi awmzia chu i nu emaw, i pa emaw, i chhungte zinga tu emaw hian hetiang natna hi a neih chuan nang pawhin i vei a rinawm zawk tihna a ni. Khawvela mi panga zinga pakhat velin Lp(a) level sang tak an nei niin an sawi.
Hei hi a hlauhawmna chu Lp(a) level sang tak neih hian kum naupang takah heart attack leh stroke vei theihna nasa takin a tipung a ni. A tam zawkah chuan miten he thu hi heart attack emaw stroke emaw an neih hnuah chauh an hre thin. Hei hi standard lipid panel hian he Lp(a) value hi a lantir loh vang a ni. Test hran a ngai a ni.
Entirnan, kum 66 mi Bernadette-i chanchin hi han la ila, ni khatah mel 10 vel zet kein a kal a, thlai chi hrang hrang, thlai leh tofu te pawh a ei thin. A cholesterol level chu a tlangpuiin a tha lam a ni a, mahse a Lp(a) level chu risk level aiin a let nga zetin a sang zawk thung. Hei hi a genetics vang a ni. A nu leh a pi te pahnih hi thinlung natna vangin an thi tawh a ni.
Bernadette chuan, "Ka tan chuan harsatna lian ber chu hei hi ka nunpui avanga ka rilru hahna hi a ni. Tlemte natna nei mah ila, 'Hei hi ka heart attack tur chu a ni em?'
Buaina leh beiseina thar
Tun thleng hian Lp(a) level tihhniamna tur damdawi bik pawm a la awm lo. Chumi awmzia chu a awm tih hre mah se, mi tam tak chuan hlauhna neiin an khawsa a ngai tawh a, chu chu engmah tih theih an nei lo tihna a ni. An taksaah engtik lai pawha puak thei tur time bomb an neih ang mai a ni.
Mahse, tunah chuan chu dinhmun chu a danglam dawn ta!
Tunah hian medical researcher-te chuan damdawi thar panga an zirchiang mek a, zirchianna hmasa berah chuan Lp(a) level nasa takin a tihhniam tih hmuhchhuah a ni. Hei hi Lp(a) level sang tak nei mi maktaduai tam tak tan chuan beiseina ropui tak a ni. Lead researcher Dr. Steven Nissen-a sawi angin, " Lungngai suh, solution a lo thleng dawn a ni. "
Damdawi thar ber ber zirchianna stage-a awm mekte
Heng damdawi tharte hi zirchianna hnuhnung ber (clinical trials)-ah an la awm mek a ni. An hlawhtling a nih chuan nakin lawkah market-ah an awm thei dawn a ni. Chu damdawite chu eng nge ni a, engtiang chiahin nge a hlawhtlin tih i lo en ang u.
| Ruihhlo Hming | Feature / A pek dan tur | Beisei ang result a ni |
|---|---|---|
| Pelacarsen chuan a rawn ti a | Thla khatah vawi khat injection pek thin | Lp(a) level hi 80% velin a tlahniam thei a ni. |
| Olpasiran a ni | Thla 3 danah vaccine pek thin a ni | Lp(a) level hi 95% aia tam tihhniam theih a ni. |
| Lepodisiraran tih a ni | Vaccine pakhat, kum khat dawn lai active reng | Lp(a) level hi 94% velin tihhniam theih a ni a, rei tak a awm thei bawk. |
| Zerlasiran chuan a ti a | Vaccine pek tlem tak a ni | Lp(a) level hi 86% velin a tlahniam thei a ni. |
| Muvalaplin a ni | Nitin pill pakhat | Lp(a) level hi 86% velin a tlahniam thei a ni. |
Muvalaplin tablet hi eng nge a danglam bik?
Heng zingah hian zirchiangtute chuan damdawi ``(Muvalaplin)'' tih chu beiseina sang tak an nei a, a chhan chu damdawi dang palite hi injection anga pek a ngai laiin, hei hi nitin pill anga ei theih a nih vang a ni Chuvangin damlo tan a awlsam zawk thei a, a man pawh a tlawm thei bawk.
Damdawi dangte chuan Lp(a) siamna atana mawhphurtu gene chu silencing hmangin hna an thawk a ni. Mahse he pill hian kawng dangin hna a thawk thung. A laiah Lp(a) particle siam chhuah a titawp a ni. Hei hian thin (liver) tichhe lovin hna a thawk thei a, side effect a awm chuan taksa atangin a bo nghal vat thei bawk.
Engvangin nge Lp(a) test kan mamawh?
He thuziak i chhiar lai hian, ‘Hei hi ka check ve tur em ni?’ tiin i ngaihtuah mai thei. A chhanna chu, a ni! Hei hi i ngaihtuah ngei tur a ni, a bîk takin i chhûngkuaa mi tu emaw chuan a naupan lai aṭanga thinlung natna emaw, stroke emaw a neih chuan .
Tunah chuan National Lipid Association chuan mi zawng zawngin an dam chhungin vawi khat tal an Lp(a) level enfiah vek turin a rawt a ni . Genetic thil a nih avangin nun chhung zawngin level hi a danglam vak lo. Vawi khat check tir mai mai chu a tawk.
Hei hi thisen test awlsam tak a ni. Mahse, standard cholesterol report-ah a tel loh avangin he test hi i tih hmain i doctor hnenah he thil hi chiang takin i zawt hmasa tur a ni.
I Lp(a) level hriat hi a hmasa ber a ni. A sang a nih chuan hlauthawng suh. Heng damdawi thar te hi a lo thleng thuai dawn a, heart attack leh stroke i vei theihna tur i control thei tawh ang. Chumi hma chuan risk factor dang, thisen sang, zunthlum, meizuk, leh LDL cholesterol level te chu uluk taka control a pawimawh.
Take-Home Thuchah a ni
- Lipoprotein(a), a nih loh leh Lp(a) hi cholesterol chi khat a ni a, genetically controlled a ni a, thinlung natna vei theihna a tipung a ni.
- Hei hi cholesterol test pangngai (lipid profile)-ah a tel lo va, chuvangin i doctor hnenah he thil hi zawt la, a bik takin i check tir tur a ni.
- I chhungkuaa mi tu pawhin kum naupan lai atanga thinlung natna nei tawh an nih chuan he test hi tihsak a pawimawh hle.
- Tunah hian Lp(a) damdawi chiang tak awm lo mah se, damdawi engemaw zat, result beisei awm tak tak lantir mekte chu zirchianna hnuhnung ber an ni. Hei hi a beisei awm tak a ni.
- I Lp(a) level a sang tih i hriat chuan hlau suh la, i doctor nen sawiho la, heart disease risk factor dangte pawh control la.
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