Doctor-in hnute cancer i vei thu a hrilh che chuan hlauhna leh mangang tak tak i nei ngei ang. ‘Tunah hian eng nge ka tih ang?’, ‘Eng damdawi nge ka pek ang?’, ‘ Chemo ka nei dawn em ?’ tih te a rawn ti leh a. Zawhna tam tak ka rilruah a lo thleng ngei ang. Cancer dona hi zinkawng awlsam a ni lo tih kan hria. Mahse tunlai damdawi lam thiamna hian hma a sawn nasa hle. Hetiang hun lai hian vawiin hian doctor-te’n eng enkawlna nge an pek ang tih chiang taka an hriat theihna tur test bik kan sawi dawn a ni.
Oncotype DX chu eng nge ni?
A awlsam zawngin, Oncotype DX hi test bik a ni a, i hnute cancer cells te chu thuk takin a enfiah thin. Thisen test pangngai a ni lo. Biopsy atanga cancer tissue lak chhuah hmangin i cancer tih chian nan emaw, operation atanga lak chhuah emaw hmangin tumor lakchhuah a ni.
He test hian cancer cell chhunga gene thenkhat hnathawh dan a enfiah thin. Kan cell zawng zawng ang bawkin cancer cell pawh hian gene an nei ve bawk. Heng genes te hian cancer awm dan te, chu chu a nasat dan te, a darh chak dan te, enkawl hnua a lo let leh theihna tur te a hril a ni.
Oncotype DX test hian gene 21 a ngaihtuah a, hei vang hian “21-gene signature” test an tih hi i hre mai thei. Heng gene pattern te hi an zirchian hian doctor-te chuan i cancer chungchangah thu pawimawh tak tak an zir thei a ni.
He test hi tute nge tih tura rawtna awm?
He test hi hnute cancer vei zawng zawng tan a ngai lo. A hnuaia natna i neih chuan i doctor chuan he test hi a rawt zawk ang:
- Early stage cancer (Stage I or II) i neih chuan: Hei hian cancer chu taksa hmun hla takah a la darh lo tihna a ni.
- Cancer chu estrogen-receptor positive (ER+) a nih chuan: Chumi awmzia chu i taksain hormone estrogen a siam avangin cancer cell te hi an thang lian tihna a ni. Hetiang cancer hi hormone therapy hmanga enkawl a ni tlangpui .
- Cancer hi ke chhunga lymph node-ah a darh lo a nih chuan.
Tin, he test hi a chang chuan cancer natna hmasa ber nei tan pawh tih theih a ni a, chu chu DCIS (Ductal Carcinoma in Situ) , radiation therapy a ngai em tih hriat theihna atan a ni.
A pawimawh ber chu he test atanga tanpuina lian ber chu hormone therapy bakah chemotherapy treatment i mamawh leh mamawh loh tur chungchanga kaihhruaina i hmuh hi a ni.
Engtin nge test score i chhiar thin?
Oncotype DX test hian “Recurrence Score” 0 leh 100 inkar a pe che a, he score hi a san poh leh enkawl hnuah cancer a lo let leh theihna a sang zawk. Mahse, he score chhiar dan hi i kum a zirin a danglam deuh ang.
| Score Range a ni | Tum chhin | Thurawn awm thei |
|---|---|---|
| 0 – 25 a ni | Risk a hniam | Hormone therapy ringawt pawh a tawk mai thei. Chemotherapy atanga hlawkna dang hmuh theihna chance a tlem hle . |
| 26 – 100 ah a awm | Risk a sang zawk | Cancer lo kir leh theihna chance a sang hle. Chemotherapy hi a tha ang bawkin hormone therapy pawh a tha thei bawk. |
| Score Range a ni | Tum chhin | Thurawn awm thei |
|---|---|---|
| 0 – 15 a ni | Risk a hniam | Hormone therapy ringawt pawh a tawk mai thei. Chemotherapy atanga hlawkna dang hmuh theihna chance a tlem hle. |
| 16 – 20 ah a awm | Risk hniam-medium a ni | Chemotherapy hian hlawkna tlemte a pe thei a, mahse a side effects nena khaikhin chuan a hlawkna chu a hlu em tih doctor nen in sawiho tur a ni. |
| 21 – 25 ah a awm | Risk hniam tak a ni | Chemotherapy hlawkna hian a side effects hlauhawmna a tluk pha thei a ni. Hei hi i doctor nen in sawiho tur a ni a, thutlukna siam tur a ni. |
| 26 – 100 ah a awm | Risk a sang zawk | Cancer lo kir leh theihna a sang hle. Hormone therapy nen hian chemotherapy hi a tha zawk. |
He chhinchhiahna chauh hian enkawlna a hril tur em ni?
Ni lo tak zet a ni. Hei hi a pawimawh hle. Oncotype DX score hi thutlukna siamna atana puitu tur thil chak tak pakhat chauh a ni. I doctor chuan i tana enkawlna tur ruahmanna tha ber a siam hmain thil dang tam tak a ngaihtuah hmasa ang.
Entir nan:
- Tumor lian leh te
- Tumor grade a ni
- Cancer cell-a hormone receptor awm zat
- I kum leh i hriselna zawng zawng
Heng zawng zawng hi thutlukna hnuhnung ber siam turin a inzawm khawm a ni. Chuvangin, he test report hi i doctor-in i tana enkawlna tur ruahmanna tha ber siamsak theitu hmanraw pakhat chauh a ni.
Hetiang genetic test dang hi a awm em?
Ni e, hnute cancer atana hman thin genetic test dang engemaw zat a awm bawk. Mahse hman lar ber chu Oncotype DX a la ni reng. Midangte chanchin tawi te tein han zir ila.
- MammaPrint: Hei hian gene 70 a test a. Hnute pawn lama cancer darh theihna tur a hrilhfiah thei a ni. ER+ leh ER- type pahnih tan pawh hman theih a ni.
- Mammostrat: Hei hian gene 5 a test a, early-stage hormone-receptor positive hnute cancer lo kir leh theihna a teh a ni.
- Prosigna: Hei hi postmenopausal hmeichhia hormone-receptor-positive hnute cancer atan hman a ni. Gene 58 a zirchiang a, kum 10 chhunga taksa hmun dangah cancer a lo kir leh theihna tur a sawi lawk a ni.
Heng zawng zawng hi advanced test a ni. I doctor chuan heng zinga pakhat i mamawh leh mamawh loh leh eng nge a remchang ber tih a rel ang.
Take-Home Thuchah a ni
- Oncotype DX hi special test a ni a, hnute cancer cells genes te enfiahna a ni a, cancer lo lang leh theihna tur leh chemotherapy a ngai em tih hriat theih nan a pui thin.
- Hei hi thisen atanga lak ni lovin biopsy emaw surgery atanga lak cancer tissue piece hmanga tih a ni.
- He test hi mi zawng zawng tan a ngai lo. Cancer Stage I/II, ER+, lymph node-a darh lo tan hman a ni ber.
- Test score hi treatment plan-a a then pakhat chauh a ni. I doctor chuan thil dang tam tak a ngaihtuah ang a, chu chu cancer lian leh te, a nasat dan te, leh i kum te hi a ni.
- Hemi chungchanga zawhna emaw, ngaihtuahna emaw i neih chuan i doctor nen zalen takin inbiakna nei ngei ang che . I tana ṭha ber tur thlang turin a pui ngei ang che.
Oncotype DX Sinhala, Hnute cancer, Chemotherapy, Cancer Genetic Testing, Cancer lo lang leh, ER Positive Cancer , Cancer Enkawlna
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