I lungah thisen kalna kawng a zim bawk em? Pulmonary Arterial Hypertension (PAH) chungchang hi han sawi ila!

A chang chuan thawk hah deuhin i inhria em? A nih loh leh, hla vak lo i kal lai pawhin a danglam bik takin i chau tih i inhria em? I kut zungtang leh hmui chu a rawn sen rualin i rilru a tight emaw, a na emaw a awm tih i hmu ngai em? Hengte hi thil pangngai mai mai angin hnawl suh. A chhan chu a chang chuan heng symptoms hnuaiah hian hriselna lama harsatna engemaw chen ngaihven ngai a awm thei a ni. Chutiang dinhmun pakhat chu Pulmonary Arterial Hypertension (PAH) a ni. A hming hi a hlauhawm deuhin a lang thei a, mahse awlsam tak leh i hriatthiam theih angin i sawi dawn nia.

Pulmonary Arterial Hypertension (PAH) hi eng nge ni? A awlsam zawngin...

A awlsam zawngin sawi ila, Pulmonary Arterial Hypertension (PAH) hi i lung chhunga thisen kalna kawng te tak te (pulmonary arteries) te chu a zim deuh thin a ni. Tui pipe inkhar ang maiin han ngaihtuah teh, chuta tui luang chhuak chu a harsa khawp mai. Heng thisen kalna kawngte hi a zim deuh chuan thisen chu i lungah a kal tha thei lo. Hei hian heng thisen kalna kawng chhunga pressure, a nih loh leh thisen sang lutuk chu a ti sang lutuk a ni . Heng thisen kalna kawngte hian i thinlung atanga oxygen tlachham thisen chu i lungah a phur a, chutah chuan a tifai thin.

Chuti a nih chuan hetiang thil hi a thlen hian eng nge thleng? I thinlung dinglam hian lung chhunga thisen pump turin a hma aia nasa zawkin hna a thawk a ngai a ni. Thil rit tak chawi a, tlang lawn ang mai a ni. Hun kal zelah thinlung hian he phurrit belhchhah hi a phur a ngai a nih chuan zawi zawiin a chak lo tan thin. Enkawl that loh chuan he natna, PAH hian i thinlung leh lung tan chauh ni lovin, i taksa pum tan pawh harsatna hrang hrang a thlen thei a ni.

PAH hi pulmonary hypertension chi khat bik chauh a ni tih hre reng ang che, chu chu eng thil vang pawha lung thisen kalna kawnga pressure a sanna dinhmun a ni.

PAH hian engtin nge i taksa a nghawng?

Pulmonary Arterial Hypertension (PAH) hian i thinlung dinglam a pressure a siam ber a ni. Hei hi a chhan chu he thinlung peng hian oxygen tlachham thisen chu lungah a pump lut a ni. Hun a kal zel a, he pressure sang tak hian dinglam heart failure a thlen thei a ni .

Chu mai ni lovin, PAH hian thinlung leh lung inkara thisen kal dan a tikhawtlai bawk. Chumi awmzia chu oxygen thar dawng turin lungah thisen a thleng tlem zawk tihna a ni. Chuvang chuan i taksa peng leh tissue dangteah oxygen a lut tlem zawk a ni. Dik tak chuan kan taksa peng tin hian dam khawchhuah nan oxygen kan mamawh a. A tling tawk lo a nih chuan harsatna a lo chhuak thin.

He dinhmun hi engtiang chiahin nge PAH tia koh a nih?

Pulmonary Arterial Hypertension (PAH) hi natna khirh tak a ni a, a chang chuan nunna atana hlauhawm tak a ni . Mahse, a hmaa hriatchhuah a nih a, enkawl vat a nih chuan dam rei zawk, nun tha zawk i nung thei a ni. Chuvang chuan a natna lan chhuah dan ngaihven a pawimawh hle.

PAH hian tute nge a nghawng nasa ber?

PAH hian kum eng pawh puitling a nghawng thei a ni. Mahse, hmeichhiaah a tam zawk , kum 30 leh 60 inkar a ni tlangpui a, mipa kum 65 chunglam PAH vei te pawhin he natna hi an vei theihna a sang zawk tih hmuhchhuah a ni bawk.

Hetiang dinhmun hian nausen te pawh a nghawng thei a ni. Nausen piang thara a awm chuan Persistent Pulmonary Hypertension in the Neonate (PPHN) kan ti thin.

PAH hi engtiang chiahin nge a awm?

Pulmonary hypertension chi dang, lung natna emaw, lung natna emaw avanga pulmonary hypertension nen khaikhin chuan PAH hi a awm fo lo . United States ang ramah pawh kum tin PAH vei thar 500 atanga 1,000 vel chauh hmuhchhuah a ni. Khawthlang ramah chuan a vei hi maktaduai khatah 25 vel a ni.

Pulmonary Arterial Hypertension (PAH) natna lan chhuah dan chu engte nge ni?

PAH i neih tirh lamah chuan symptom engmah i nei lo mai thei. Mi tam zawk chuan natna a zual zel angin symptoms an nei tan chauh a ni. Chung chhinchhiahna thenkhat chu:

• Kut zungtang emaw hmui emaw blue discoloration: Thisenah oxygen tlakchham ang maiin.
• Chest na emaw tightness emaw: Miin i rilru a rawn hrual ang maiin.
• Luak chhuak emaw, muthilh emaw: Hei hi thluaka thisen kal a tlem chuan a thleng thei.
• Fatigue: Feeling extremely tired , chau mai mai ni lovin.
• Racing emaw pounding emaw heartbeat emaw a ni.
• Thâwk hahna: Hei hi hun kal zelah a pung zel. Hna tenawm tak tak thawh pawhin thawk hahdamna a thlen thei.
• Swelling (Edema): Ke leh kekawrteah a intan hmasa thei a, chumi hnuah pum leh kawr thlengin a darh thei.

Enkawl loh chuan heng PAH symptoms te hi hun kal zelah a zual zel ang. Nitin hna pawimawh ber ber pawh thawk thei lovin i thawk thei lo va, chawlh hahdam ngai lovin i inhmu mai thei.

Pulmonary Arterial Hypertension (PAH) hi engte nge ni?

PAH thlentu ber chu i lung chhunga thisen kalna kawng lining tihchhiat a ni. Mahse, eng thilin nge he chhiatna hi a thlen tih erawh a chiang lo.

A chhan hmuh theih lohna case (Idiopathic PAH) .

A châng chuan, a chhan chiang tak hmuh theih a ni lo . Keini doctor-te chuan “idiopathic” pulmonary arterial hypertension kan ti a ni. Thuruk ang mai a ni.

A chhan hriat chhuah

Mahse, hun dangah chuan a chhan chiang tak a awm. PAH thlentu hriat chhuah ṭhenkhat chu:

• Damdawi lam dinhmun thenkhat:
• Pianpui thinlung natna
• Glycogen khawlkhawmna natna te
• HIV hrik kai
• Liver natna
• Autoimmune natna, lupus ang chi te
• Portal hypertension (liver panna thisen kalna kawng hrang hranga pressure sang) .
• Pulmonary capillary hemangiomatosis (lung chhunga capillary te lo thang dan pangngai lo) .
• Pulmonary veno-occlusive disease (lung chhunga thisen kalna kawng (veins) block) .
• Schistosomiasis (parasite atanga natna kai) .
• Scleroderma (vun leh connective tissue tihthianghlim) .

• Genetic mutations te chu: 1.1.
• A tam zawkah chuan hei hi i BMPR2 gene a mutation vang a ni . He gene hian kan taksa chhunga tissue thenkhata cell awm zat a control a. Chuvangin, he gene hi a inthlak danglam chuan i lung chhunga thisen kalna kawng te tak tea cell te chu an thang lian lutuk thei a ni. Heng cell te hi an lo khat chuan thisen kalna kawngkhar hawnna te chu a zim ta hle mai.
• PAH hi chhungkuain a kal thei. Heritable PAH kan ti a ni . Hetiang natna vei zinga 80% vel chuan BMPR2 gene-ah mutations an nei a ni.
• Mi thenkhat chuan he altered gene hi an keng tel a, mahse PAH an nei ngai lo.
• Mi thenkhat chuan an chhungkuaa tumahin PAH hi an nei lo nain an vei thei a, hei hi genetic mutation vang a ni. Hei hi sporadic PAH an ti a .

• Damdawi leh damdawi thenkhat:
• Some diet pills , damdawi hlui “fen-phen” ang chi chu tunah chuan khap a ni tawh a, mahse kum tam tak hman hnuah pawh PAH a la thlen thei tho.
• Infiamna atana ruihhlo , entirnan cocaine leh methamphetamine.

Engtin nge Pulmonary Arterial Hypertension (PAH) hi hriat theih?

PAH natna lan chhuah dan hi natna dang tam tak nen a inang avangin hriat a harsa thei hle. I doctor chuan physical exam a ti ang a, i symptoms leh medical history te a sawipui ang che. Pulmonary hypertension i neih leh neih loh leh, a nih chuan eng chi nge a nih tih hriat nan test engemaw zat (imaging test leh thisen test te pawh tel) an ti ang.

I doctor chuan pulmonologist emaw cardiologist emaw hnenah pawh a refer thei che a ni . Heng specialist te hian i thinlung leh lung hnathawh dan enfiah nan special test an nei ang. Anni hian PAH emaw, pulmonary hypertension chi dang emaw i neih leh neih loh an hril ang. I dinhmun a nasat dan pawh an zirchiang bawk ang.

PAH enkawlna bik a awm a, chu chu pulmonary hypertension chi dang tan pawh a awm lo. Chuvangin i medical team te hian i lung leh thinlunga thil thleng hi a theih ang anga hriat a ngai a ni. He thu hian i tan enkawlna ruahmanna tha ber siam turin a pui ang.

PAH hriat theihna atan eng test nge hman thin?

I medical team chuan natna dang tihbo nan leh PAH hriatchhuah nan test hrang hrang an hmang ang.

I doctor-in i taksa enfiah hnuah PAH i nei thei tih a rinhlelh chuan, an order hmasak ber tur test chu transthoracic echocardiogram a ni. He test hian i thinlung dinhmun leh hnathawh dan tlangpui a zirchiang a ni.

Test dangte chu:

• Thisen test: Organ hnathawh dan, hormone level enfiah a, natna hnuaia awmte hriatchhuah. A bik takin test metabolic panel kimchang leh thisen count kimchang ang chi te .
• Chest CT scan: Kal natna ang chi natna dang enfiah leh paih loh nan. (A original article-a kal natna hi lung natna a ni tur a ni mai thei. CT chest scan hmangin lung leh chest organs te chu a en a. Lung dinhmun kan en ang u.
• Chest X-ray: I thinlung emaw, i pulmonary arteries emaw chu a tlangpui aia lian a nih leh nih loh hriat nan.
• Heart MRI: I thinlung ventricle dinglam (hei hi lung chhunga thisen pump chhuahna chamber a ni) dinhmun endik rawh.
• Polysomnogram (PSG): Sleep apnea a awm leh awm loh a enfiah a, hei hian PAH a ti na zual thei. PSG hi zan khat chhunga mut test chi khat a ni.
• Pulmonary function tests: I lung hnathawh that dan en rawh.
• Pulmonary ventilation/perfusion (VQ) scan: Lung chhunga thisen zam awm leh awm loh enfiah thin. He test hian chronic thromboembolic pulmonary hypertension tih natna chu a paih chhuak thei a ni .
• Right heart catheterization: I lung chhunga thisen kalna kawng (pulmonary artery pressures) a teh thin. He test hi PAH chiang taka hriat theih nan a pawimawh hle.
• Minute ruk chhunga kal test: Exercise i tuar theih zat leh i che vel hian i thisenah oxygen engzat nge a kal kual tih en rawh.

Eng test nge i neih a ngai tih leh chutiang atana i inbuatsaih dan tur chu i doctor nen sawiho rawh.

Pulmonary Arterial Hypertension hriat theihna tur criteria te chu engte nge ni?

Doctor-te chuan i lung chhunga thisen kalna kawng hrang hranga pressure tehna hmangin pulmonary hypertension an hmuchhuak thin. Diagnostic criteria chu i lung chhunga pulmonary arterial pressure chu i chawlh laiin mercury millimeter 20 (20 mmHg) aia tam a ni He value hi right heart catheterization hmanga teh a ni .

Pulmonary Arterial Hypertension (PAH) hi eng enkawlna nge ni?

PAH enkawlna tum ber chu natna kal zel dan tur control leh nunphung tha zawk pek che hi a ni. PAH hi enkawlna pakhat chauh a awm lo. I doctor chuan i mamawh bik atana enkawlna tha ber tur chu a ngaihtuahpui ang che.

I PAH enkawlna ruahmannaah hian:

• Balloon atrial septostomy (BAS): Hetiang tih dan hi naute pianpui heart defect nei tan tih a ni tlangpui a, mahse PAH vei puitling tan erawh hman a ni. Septostomy hian thinlung dinglamah pressure a tihziaawm a, thisenah oxygen tam zawk a kal thei a ni. Lung transplant-na kawngpui (bridge) atan pawh tih theih a ni.
• Calcium channel blockers: Heng damdawi te hian i lung chhunga thisen kalna kawng leh i taksa pum puia thisen sang tihhniam nan a pui thin.
• Diuretics: "Tui pills" tia hriat bawk, ​​heng damdawi te hian taksa atanga tui tam lutuk te chu a paih chhuak a, a hring (swelling) a ti tlem bawk.
• Oxygen therapy: I thisenah oxygen i neih tlem chuan he enkawlna hi a ngai mai thei. Extra oxygen hian chawlh hahdam, mut leh exercise i tih hian a pui thei a ni.
• Pulmonary vasodilators: Heng damdawi te hian i lung chhunga thisen kalna kawng (pulmonary arteries) te chu a ti hahdam a, a zau zawkin a inhawng thin. Hei hian i thinlunga harsatna awm chu a tiziaawm a, i natna lan chhuah dan a tiziaawm bawk.

PAH na tak nei thenkhat tan chuan lung transplant hi a hnuhnung ber a ni thei. He surgery hian lung thar pakhat emaw pahnih emaw a pe thei che a ni. Heart-lung transplant hian thinlung thar a pe thei bawk.

PAH tan hian eng damdawi nge pek thin?

PAH enkawlna damdawi hi chi hrang hrang a awm a:

• Damdawi ei: Heng damdawi te hian lung chhunga thisen kalna kawngte a ti hahdam a, a zim loh nan a pui bawk. Heng damdawi te hian taksa tihchakna kawngah pawh a pui thei che a ni.
• Inhaled medications: Thâwk lama harsatna awmte enkawl.
• Portable infusion pump: Hei hian thisen kalna kawng a hawng thei a, thisen kal a tipung thei bawk. Hei hian i symptoms a ti tha thei a ni.
• Intravenous (IV) damdawi: Thisen kalna kawng hawn a, rilru na leh thawk harsa ang chi symptoms te a reh thei.

US Food and Drug Administration (FDA)-in PAH vei te tana a pawmpui damdawi thenkhat chu hetiang hi a ni:

• Ambrisentan (oral) hmanga tih a ni.
• Bosentan (oral) a ni.
• Epoprostenol (IV) a awm bawk.
• Iloprost (thil thawh chhuah) .
• Macitentan (oral) hmanga tih a ni.
• Riociguat (oral) a ni.
• Selexipag (oral) a ni.
• Sildenafil (oral) hmanga tih a ni.
• Tadalafil (oral) hmanga tih a ni.
• Treprostinil (oral, inhalation, pump, IV) hmanga ei theih a ni.

PAH damdawi ei avanga side effects awm thei

PAH enkawlna atana damdawi hmante side effects awm fo thenkhat chu:

• Luak chhuak emaw, muhil emaw tih hriat.
• Hmai, kawr emaw, kut emaw a lumna hriatna (flushing).
• Gastrointestinal symptoms te, puar, luak chhuak, luak chhuak, leh riltam te.
• Lu na (lu na).
• Thisen sang hniam (Hypotension) .
• Ke leh ke ruh a hring (Pedal edema) .
• Vun a hring chhuak.
• Upper respiratory tract congestion tih hriatna.

Damdawi thenkhat chuan side effect dang a nei thei bawk. I doctor nen side effect eng pawh enkawl dan tur sawipui rawh. Thil engemaw takah chuan i doctor chuan i damdawi ei tur zat a thlak a ngai mai thei.

Pulmonary Arterial Hypertension (PAH) hi a dam kim thei em?

Tuna damdawi hman mekte hian PAH kal zel dan chu thunun thei mah se, chhiatna lo thleng tawh chu a tidanglam thei lo . Mahse, zirchiangtute chuan PAH tidanglam thei tura an ngaih damdawi thar an chhui mek a ni. Chutiang damdawi chuan i lung chhunga thisen kalna kawngkhar line tu endothelial cells chhiatna chu a siam tha thei a ni.

PAH enkawlna atana zirchianna leh clinical trial thar ber berte hriat belh duh chuan i doctor nen inbia ang che.

Eng thil nge mi pakhatin Pulmonary Arterial Hypertension (PAH) a vei theihna tipung?

PAH vei theihna tipungtu thil engemaw zat chu:

• Connective tissue natna a ni .
• Down syndrome tih hi a ni .
• Chhungkaw history-a pulmonary hypertension nei.
• HIV hrik kai.
• “Fen-phen” (dexfenfluramine leh phentermine) ang chi taksa rihna tihtlem nan hman.
• Dan lova ruihhlo (street drugs) hman.

I chhungkuaa mi pakhatin PAH a neih chuan i doctor hnenah genetic testing chungchang zawt rawh. PAH i vei tih hmuhchhuah a nih chuan i chhungte hnenah pawh genetic testing ngaihtuah turin ngen a tha.

Pulmonary Arterial Hypertension (PAH) hi engtin nge kan ven theih ang?

PAH vei theihna tur risk factor thenkhat (genetic mutations ang chi) kan control thei lo. Mahse, dan loa ruihhlo laka inthiarfihlim hian PAH chauh ni lovin, hriselna lama harsatna dang tam tak i neih theihna a ti tlem thei a ni. Tin, taksa rihna tihtlemna damdawi eng pawh i ei hmain i doctor nen inbiakna neih hmasa phawt ang che.

I risk factors a zirin i doctor chuan PAH venna screening neih a rawt thei ang.

Pulmonary Arterial Hypertension (PAH) vei te hmalam hun tur chu eng nge ni?

Enkawlna lama hmasawnna a awm avangin PAH vei te chu a hma aia rei zawkin an dam rei tawh a ni. I dam rei zawng hi thil tam takah a innghat a, chung zingah chuan i natna nasat dan leh i natna hriat hma dan te pawh a tel. I dinhmun bik chungchang chu i doctor nen sawiho rawh.

A pawimawh ber chu i enkawl chhunzawm zel a, i doctor thupek uluk taka zawm hi a ni. I dam khawchhuah theihna chance tihsan nan thil tlemte i tih theih a awm a:

• Emergency kit siam rawh. Supply leh information thenkhat i neih reng tur a awm. I kit-a i dah tur chu i doctor hnenah zawt la, chutiang tel lo chuan in chhuahsan ngai suh.
• Doctor-in a rawt angin seasonal vaccine la rawh. Flu leh pneumonia laka inven a pawimawh hle.
• Follow-up appointment zawng zawng chu vawng reng rawh. I lung leh thinlung hnathawh dan enfiah nan leh i enkawlna kal zel dan tehna atan check-up neih fo hi a pawimawh hle.
• I damdawi ei tur chu i doctor-in a tih ang chiah chiah, nitin hun khata ei thin ang che. Doctor thurawn tel lo chuan i damdawi ei dan hi thlak danglam suh.

Eng nunphung tihdanglamna nge ka neih?

Nunphung tihdanglam i duh apiang chungchangah doctor thurawn zawm rawh. A tlangpuiin, tips pawimawh thenkhat chu hetiang hi a ni:

• Hot tub, sauna leh hmun sang taka zin te chu pumpelh rawh.
• Nau neih dan tur ngaihtuah rawh. PAH vei tan chuan naupai hi a hlauhawm thei hle. Naupai i tum a nih chuan emaw, naupai theih i nih chuan i doctor nen inbia ang che.
• Exercise la, a theih ang anga active takin awm rawh. I doctor nen eng exercise nge i tan a him tih leh nitin engzat nge i tih tur tih te sawipui rawh. Exercise program thar i tan hmain doctor zawt hmasa phawt ang che.
• Thinlung hrisel ei leh in zawm rawh. Hei hian saturated fat tlem, trans fat, leh sodium te a huam a ni.
• Meizial zu leh zuk leh hmuam thil hman kha bansan rawh. Tin, secondhand smoke pawh pumpelh tur a ni.
• Support zawng la, i PAH zinkawng chu nangmah chauhin kal tum suh. I doctor hnenah support group leh resources chungchang zawt rawh.

Engtikah nge ka doctor ka biak ang?

Heng zawhnate hi i neih chuan doctor ko rawh:

• Heart rate hi minute khatah beat 120 aia tam a nih chuan (fast heart rate).
• Thluak lam natna emaw khuh a nasat chuan.
• I luak chhuak emaw, i muhil emaw fo chuan.
• Taksa tihchakna avanga rilru natna emaw, nuam lo emaw i neih chuan.
• I hahna nasa lutuk emaw, hna pangngai thawh theihna tlahniam emaw i neih chuan.
• Nausea emaw ei duh lohna emaw.
• Restlessness emaw, buaina emaw.
• I thawk hah a na zual a nih chuan, a bik takin i harh hunah thawk harsa i tih chuan.
• I ke ruh, i ke emaw, i pum emaw a hring a nasat chuan.
• Thil tih dan pangngai emaw, chawlh lai emawa thawk harsatna.
• Taksa rihna (ni khatah pound 2 emaw kar khatah pound 5 emaw).

Engtikah nge Emergency Treatment Unit (ETU) ah ka kal ang ?

Heng thilte hi i neih chuan emergency room-ah kal la, i awmna hmuna emergency number-ah emaw call rawh:

• Heart rate (minute khatah beat 120-150) a tlahniam loh chuan.
• Fainting, hriatna hloh thlentu.
• I IV emaw infusion pump atanga harsatna (infection, catheter chhuah, solution leakage, thisen chhuah, IV pump malfunction ang chi).
• Thâwk hahdamna chu chawlh hnuah pawh a reh loh chuan.
• Rilru na tak leh na tak.
• Lu na tak leh na tak a ni.
• Kut emaw ke emaw chak lohna emaw, paralysis emaw a awm nghal.

A tawp berah chuan thuchah hriat reng tur

Pulmonary Arterial Hypertension (PAH) hi nun tidanglam thei a ni. Nangmah emaw, i hmangaih tak emaw hian he natna hi i vei tih hmuhchhuah thar i nih chuan, chu natna chungchang leh i beisei theih turte zir turin hun hmang rawh. PAH hnathawh dan leh enkawlnain a puih theih dan sawifiahna resources chungchang i doctor zawt rawh.

I neih theih thil hlu ber pakhat chu i nunah midangte puihna hi a ni. He dinhmun hi nangmah chauhin enkawl tum suh. I chhungte leh i thiante an awm loh chuan i doctor hnenah support group leh community resources chungchang zawt rawh.

I hmangaih tak chu he natna hi a vei tih hmuhchhuah a nih chuan, anmahni thlawp a nih theih nan theihtawp chhuah la, midangte nena inzawmna siam turin tanpui rawh. Natna hian kawng engemaw takah chuan inhlat takin min awmtir thei a, mahse min hnaih tir thei bawk. He hun hi hmang la, nangmah emaw, i hmangaih tak emaw hmasawnna tura pui thei tur khawtlang din rawh.

` Pulmonary Arterial Hypertension, PAH, pulmonary hypertension, thawk hah, lung natna, lung natna, symptoms te