Spindle Cell Sarcoma hi eng nge ni? A awlsam zawngin sawi ila!

Thil mak tak tak, i ruh natna emaw, hring emaw, i taksa ruh ang chi hmun nêm emaw ang chi i ngaihtuah ngai em? A châng chuan hengte hi thil pangngai a ni thei bawk. Mahse, a tlem berah chuan heng symptoms te hi thil pawi tak chhinchhiahna a ni thei. Chuvangin, vawiin hian cancer chi khat, tlem a awm lo, mahse hriat tur pawimawh tak chungchang kan sawi dawn a ni. Chu chu Spindle Cell Sarcoma an ti a.

Spindle Cell Sarcoma hi eng nge ni tak tak?

A awlsam zawngin sawi ila, Spindle Cell Sarcoma hi cancer chi khat, kan taksa ruh leh soft tissue-a lo awm thin a ni. ‘sarcoma’ tih hian chu ruh leh a inzawmkhawmna tissue-a lo awm cell mass, a nih loh leh tumor pangngai lo tak takte a kawk tih i hria em?

Tunah chuan Spindle Cell Sarcoma chungchanga thil danglam tak chu chutiang cell pangngai lo chu microscope hmanga i en chuan ‘spindle’ ang mai an ni. Spindle hi candle ang chi a ni a, a sir lam chu a hring a, a lai chu a thim deuh bawk. Chuvang chuan a hming a pu ta a ni.

Advanced lab test avang hian doctor-te chuan sarcoma chi 75 chuang an hmuchhuak thei tawh a ni. Chutiang subtype pakhat chu Spindle cell sarcoma hi a ni. Dik tak chuan ‘spindle cell sarcoma’ tih hi lab test thenkhat, stain emaw genetic characteristic emaw hmanga dik taka thliar hran theih loh sarcoma sawina atan hman a ni. Chuvangin, thumal zau tak a ni deuh ber.

Heng tumor te hi khawiah nge an awm tam ber?

Spindle Cell Sarcoma hi kan taksa ruh sei takah a lo awm tam ber. Entir nan:

• I ke ruh (`femur`) .
• Shin ruh (tibia) 1.1.
• Kut chunglam ruh (humerus) .

Mahse, heng hmunte chauh hi a ni lo. Mi thenkhat chuan pelvis, lu leh kawng, leh taksa peng dangah spindle cell sarcomas an nei thin.

Spindle Cell Sarcoma chi hrang hrangte chu engte nge ni?

Tunah chuan en teh, sarcoma zawng zawng hi soft tissue atanga tan a ni. Chu chu thau, thau, thisen kalna kawng, nerve, leh ruh chhehvel tissue ang chi thilah te a ni. Doctor-te chuan spindle cell sarcomas hi cancer intanna cell chi hrang hrang a zirin an thliar hrang leh a.

Chutianga cell chi leh a mizia hriatthiamna hmang hian doctor-te chuan cancer hi a darh theih dan tur an zir chiang thei a ni. Hei hian enkawlna tha ber berte pawh an hriat theih nan a pui bawk.

‘Spindle cell sarcoma’ tih hi thumal zau tak ni mah se, chi hrang hrang a awm a:

• Pleomorphic Sarcoma danglamna awm lo:A hming ang bawkin he cancer chi hrang hranga cell te hi ‘undifferentiated’ an ni. Chumi awmzia chu eng cell nge cancer hi a lo intan tih a chiang lo tihna a ni. Tumor chhunga natna vei cell te hi ‘pleomorphic’ an ni a, chu chu an pianzia leh lian leh te chi hrang hranga awm tihna a ni. Phên dangin sawi ila, tumor chu cell chi hrang hrang inzawmkhawm a ni.
• Fibrosarcoma: Hengte hi fibroblast an tih cell atanga lo chhuak a ni. Fibroblasts hi kan taksaa connective tissue siamtu ber a ni.
• Leiomyosarcoma: Hengte hi smooth muscle cell atanga tan a ni. Hengte hi skeletal muscle tissue-a cell awmte nen a danglam a, chu chu kan taksa tihchet nan leh chakna kan neih nan kan hmang a ni. Smooth muscle cells hi kan taksa peng hrang hrangah te, taksa peng hrang hrangah te, ruh thenkhatah te soft tissue angin kan awm a.

Hetiang dinhmun hi engtiang chiahin nge a awm?

Sarcoma chi dang ang bawkin spindle cell sarcoma hi a tlem hle . Dik tak chuan ruh leh soft tissue cancer zawng zawng zinga 10% aia tlem lo a ni. Hriat reng tur chu, a tlem em em a, i doctor chuan a tir lamah hetiang cancer hi a ringhlel lo mai thei. Doctor appointment engemawzat i kal a ngai mai thei a, specialist engemawzat i hmuh a ngai mai thei a, diagnosis i hmuh hmain test eng emaw zat i neih a ngai thei bawk.

Spindle cell sarcoma hi tu pawhah a lo awm thei. Mahse, kum 40 chunglam ah a tam ber a, a hmaa kan sawi tawh ang khan undifferentiated pleomorphic sarcoma vei te hi kum 60 leh 70 inkar an ni tlangpui.

Hei hi eng symptoms nge ni?

Spindle cell sarcoma symptoms hi a inang lo thei hle. Anni chu tumor lian leh te, tumor awm zat, leh eng ruh (or taksa peng dang) nge cancer cell-te awmnaah a innghat a, a bik takin i fimkhur tur symptom thenkhat chu hetiang hi a ni :

• Ruh natna: He natna hi a awm reng thei a, a lo thleng thei bawk. Miin chhungril atanga a hliam che ang maiin a awm thei.
• Cancer natnain a chak lohna hmuna ruh a tliak: Hei hi ‘pathological fracture’ an ti. Ruh chu a tlak tlem pawhin a chhe thei.
• Tumor awmna hmuna press a nih chuan a hring emaw, a hring emaw: Kut chhunga vawn theih tur khawpa lian tumor pawh a awm thei.
• Tumor hnaih taka ruh sawn theih lohna: Khup hnaih a nih chuan khup ben emaw, tihzauh emaw a harsa ang tih han ngaihtuah teh.
• Chauhna: Hei hi hahna pangngai mai a ni lo. Eng ang pawhin mut emaw, chawlh hahdam emaw pawh ni se, a bo ngai lo, hah lutuk a ni.
• Malaise: Feeling unwell , chhan hriat loh, engmah chakna leh ngaihvenna nei lo ang maia awm.

Eng thilin nge spindle cell sarcoma hi a thlen?

Cancer dang zawng zawng ang bawkin spindle cell sarcoma hi cell hrisel tak takte chu malignant an nih atanga tan a ni. Heng malignant cells te hi control theih lohvin an thang lian a, tumor an siam thin. Heng tumor te hian a chhehvel tissue hrisel tak tak te chu a tichhe thei a ni. A hlauhawm ber chu heng cancer cells te hian a bul tanna tumor atang hian an inthen darh thei a, taksa pum puiah an darh thei a, tissue leh organ dangte a tichhe thei a ni. Hei hi metastasis, a nih loh leh metastatic cancer kan tih chu a ni.

Mahse, hetah hian hriat tur a awm. A tlangpuiin spindle cells (an thang tha a nih chuan) hi a takah chuan thil tha tak a ni. Tissue chhiat tawhna hmunah chuan spindle cells a lo awm thin. Chuvangin, spindle cell neih hi i hliam a dam tawh tih chhinchhiahna a ni. Heng cell te hi hliam a dam chuan an bo vek a ni.

Mahse, spindle cell sarcoma-ah chuan heng spindle cell te hi an lo thang lian zel a, an pung zel bawk. Scientist-te chuan heng cell-te hi an natna hlauhawm tak an nih chhan chiang tak pakhat mah an la hmu lo .

Mahse, zirchiangtute chuan genetic mutations thenkhat hian mi pakhatin he cancer a vei theihna a tipung thei tih an hmuchhuak a ni. ‘Mutation’ chu kan genes, kan cell-te hnathawh dan tur hrilhtu system-a tihsual a ni. Spindle cell sarcoma-ah chuan heng mutations te hi hereditary a ni fo a, chhungkaw hrang hrangah an kal thei tihna a ni.

He cancer vei theihna tipungtu risk factors te chu engte nge ni?

Spindle cell sarcoma vei theihna tipung thei thil engemaw zat a awm. Eng nge an nih hi han thlir ila:

• Bone Infarction: Hei hi ruh tissue a thih hian thisen a hmuh tlem avangin a ni. I hriat angin ruh tissue hian a dam khawchhuah theih nan thisen a mamawh a, chu chu oxygen hian a ti a ni.
• Fibrous Dysplasia: Hetiang dinhmunah hian ruh hrisel tak chu ruh ang chi fibrous bone-in a thlak a ni. Hei hian ruh tliak theihna a tipung a, (a tlem hle) fibrosarcomas a thlen thei bawk.
• Osteomyelitis: Hei hi ruh thenkhat chhunga spongy tissue, bone marrow an tih, natna hrik a ni. Hei hi bacteria emaw hrik dang emaw i thisen atanga ruh thlenga kal a, chuta cell awmte a kai chuan a thleng thei a ni.
• Paget-a ruh natna: Hei hi hun rei tak (chronic) natna a ni. Ruhte a tichak lo va, awlsam takin a tikehsawm bawk. Hei hian ruh cancer vei theihna a tipung thei a, spindle cell sarcoma pawh a tel.
• Tun hmaa cancer natna avanga radiation therapy lo dawng tawh:Radiation therapy hian cancer cells te tihchhiat nan high-energy rays (a tam zawkah chuan high-energy X-rays) a hmang thin. Radiation hmanga enkawl hmunah hian spindle cell sarcomas a lo awm tam lo hle. Chutiang a nih chuan sarcoma hi enkawl a nih atanga kum engemaw zat (kum sarih atanga kum sawmhnih) hnuah a lo awm tlangpui. Mahse hre reng ang che, radiation therapy dawngtu zinga 1% aia tlem chuan he radiation-related cancer chi hi an vei thin.

Spindle cell sarcoma hian eng harsatna nge a thlen?

He cancer hian i ruhte chu tumor awmna hmunah a chhe (fracture) duh zawk a ni. Ruh a tliak chuan tumor atanga cancer cell te chu a hnaih ber hmunah an kal thei a ni.

Mahse, he ruh tliak chi hian cancer prognosis pum pui (chu chu a chhuah theih dan tur)-ah danglamna a siam em tih leh, a chhuah dan chu hla taka cancer darh zel (metastatic spread) nen chauh a inzawm em tih chungchangah hian sawiselna a la awm reng a ni.

Engtin nge spindle cell sarcoma hi an hriat theih?

I doctor-in i cancer a hriatchhuah a, a stage hmain test leh procedure engemaw zat i nei ngei ang. Cancer staging hmang hian doctor-te chuan cancer nasat dan chu tumor lian leh te, a awmna hmun leh a darh tawh loh a zirin an thliar hrang thei a ni. Bone cancer staging an tih hian tumor chu ‘high-grade’ nge ‘low-grade’ tih pawh an en bawk. High-grade tumor-ah hian abnormal -looking cells an nei tam zawk. An thang chak zawk a, an darh chak zawk bawk.

Spindle cell sarcoma tam zawk hi chu high-grade an ni.

Imaging test te pawh a awm

Imaging test-ah hian cancer chi hrang hrang hriat theih ni lo mah se, tumor lian leh te, a awmna hmun chu a lang thei a ni. Tin, cancer hi primary tumor aiin a darh tawh em tih pawh an lantir thei bawk.

• X-ray: X-ray-ah hian i ruh chhungah tumor emaw thil danglam dang emaw a awm thei. Chest X-ray hmangin cancer hi lungah a darh tawh em tih a hriat theih. Metastatic spindle cell sarcoma hi lungah a darh hmasa fo thin.
• MRI Scan: MRI hian magnet lian tak, radio wave leh computer hmangin taksa chhunga thil awmte thlalak a la thin. X-ray ang lo takin MRI hian soft tissue chu chipchiar takin a lantir thei a ni. Hei hi doctor-te tan chuan sarcomas ni thei tura an rinhlelh soft tissue lumps hriatchhuah nan a tangkai hle.
• CT Scan: CT scan hian X-ray leh computer hmangin ruh leh soft tissue te chu three-dimensional (3D) thlalak a siam a. Spindle cell sarcoma-ah chuan CT scan hmangin cancer hi soft tissue-ah a darh tawh em tih a hriat theih. Tin, ruh tliak emaw, ruh chak lohna hmun emaw zawn nan pawh an tha ber.
• PET Scans: PET scan-ah hian tracer an tih thil hmangin taksa pum puia cancer cell awmte chu a zawng chhuak thin. Anni hian metastasized spindle cell sarcoma hmuhchhuahna kawngah an pui thei a ni. I enkawlna hnathawh dan tur hriat nan PET scan pawh i nei thei bawk. Mahse, PET scan hi sarcoma chi hrang hrangah hman a ni lo. I doctor chuan PET scan hi i tan a tha em tih a rel ang.

Thisen test a ni

Thisen test chiang tak, spindle cell sarcoma hriat theihna tur a awm lo. Amaherawhchu, thisen test hian i hriselna chungchangah thu pawimawh tak tak a pe a, chu thu chu i doctor tan hriat a pawimawh hle. A tlangpuiin thisen test hian thil chi hrang hrang:

• I thisen cell te
• Organ hnathawh dan
• Enzyme level (enzyme hi taksa peng hrang hrangte thil pawimawh tak tak kalpui tura puitu chemical a ni) .

Biopsy tih a ni

Lump chu cancer a nih leh nih loh hriat chian theihna tha ber chu biopsy neih hi a ni. Cancer chi leh a grade hriat theihna awmchhun a ni bawk. Biopsy an tih lai hian doctor chuan lump atang hian tissue sample a la a, lab-ah a thawn a, cell te chu a enfiah thin.

Spindle cell sarcoma vei tam zawk chuan needle biopsy an nei thin. Doctor-te chuan tumor chhehvel tissue chu an numb a, chutah chuan needle te tak te, hollow tak hmangin sample an la a ni. Doctor-in i taksaa needle dahna hmun dik tak a hriat theih nan X-ray emaw CT scan emaw pawh i mamawh thei bawk.

Spindle cell sarcoma hi engtin nge enkawl a nih?

I enkawlna tur chu i hriselna, i awmna hmun, i lian leh te, i grade leh thil dang dangah a innghat ang. Tin, a vawi khatna atana enkawl i nih leh nih loh emaw, enkawl hnua cancer a lo let leh tawh (recurrent) emaw a innghat bawk.

Inzai

Surgery tum ber chu i ruh tam thei ang ber humhim chungin tumor chu lakchhuah a ni. Primary tumor leh secondary tumor-a cancer hnuhma zawng zawng chu paih vek theih a nih chuan cancer chu tihdam theih a ni. Mahse, cancer chu a bul tanna tumor aiin a darh tawh chuan a chhuah vek chu a harsa zawk hle.

Chemotherapy hmanga enkawl a ni

Chemotherapy hi damdawi hmanga taksa pum puia cancer cell awmte tihhlumna atana hman a ni. Surgery hmain chemotherapy pek i ni thei a, chu chu tumor tihtlem nan leh lakchhuah awlsam zawk nan a ni. A nih loh leh, operation hnua cancer cell la awm zawng zawng tihhlum turin chemotherapy pek i ni thei bawk. Chemotherapy hi ‘palliative care’ atan pawh hman a ni. Cancer a tidam thei lo nain, chemotherapy hian cancer cell te chu a that thei a, ruh na ang chi symptoms te chu a tihziaawm thei a ni.

Mi tam tak chu an enkawlna a hlawhtlin theih nan chemotherapy damdawi inzawmkhawm pek an ni. A vawi khatna atana enkawl i nih leh nih loh, chemo damdawi thenkhat i dawng tha lo em tih emaw, cancer chu ``remission''-a i luh hnua a lo let leh tawh emaw a zirin chemo damdawi hrang hrang pek i ni thei bawk. ``Remission'' tih awmzia chu cancer chu enkawl hnuah a dam tawh emaw, a bo vek tawh emaw tihna a ni.

Radiation hmanga enkawlna a ni

External Beam Radiation Therapy (EBRT) hian machine hmangin cancer cell-te tihhlum nan tumor-ah X-ray a direct a ni. Surgery i tih theih loh chuan radiation therapy hmanga tumor tihchhiat theih a ni. A châng chuan, surgeon chuan surgery hmangin tumor chu a thleng thei lo mai thei. Tissue chhunga thuk lutuk emaw, taksa peng pawimawh tak takte hnaih lutuk emaw pawh ni se, him taka lakchhuah theih a ni lo. Chutiang hunah chuan radiation therapy pek ai chuan i pe zawk mai thei.

Chemotherapy ang bawkin radiation therapy hian cancer tihdam theih loh chuan symptoms a tihziaawm thei bawk.

Enkawlna avanga harsatna emaw, a side effect emaw chu engte nge ni?

Cancer enkawl lai hian chemotherapy leh radiation therapy avanga side effects a awm fo thin. Hengte hi enkawlna zawh hnuah pawh hun engemaw chen a awm thei. I doctor hnenah a side effect awm thei te zawh a pawimawh a , chu chu enkawlna i dawn dan azirin a ni.

Engtikah nge ka doctor ka hmuh ang?

I doctor chuan enkawl tura i luh vawi engzat nge i mamawh tih a hrilh ang che, a nih loh leh cancer chu ``remission-ah a la awm em tih test neih a ngai ang.`` Cancer vei tam tak, remission-a awmte chu a tir lamah doctor pan fo a ngai dawn a ni. Cancer nei lo rei zawk i awm chuan, a lo lang leh leh tawh loh enfiah tura follow-up appointment neih zat a tlahniam ang.

Eng ang follow-up treatment nge ka mamawh?

Surgeon-in ruh engzat nge a lak chhuah a ngaih dan azirin, tih belh i mamawh mai thei. Heng procedure te hian ruh hnathawhna a vawng reng thei a ni. Entirnan, ruh (bone graft) i mamawh mai thei. Bone graft tih hian tissue lakchhuah chu i taksa peng dang atanga tissue emaw, donor atanga tissue emaw hmanga thlak a ni. Artificial limb pawh i mamawh thei bawk. Chûng inthlâk danglamnate chu i insiamrem theih nân enkawlna dang i mamawh mai thei.

Spindle cell sarcoma chungchangah hian ka doctor hnenah eng zawhna nge ka zawh tur?

I doctor zawh tur zawhna pawimawh thenkhat chu hetiang hi a ni:

• Khawiah nge cancer hi a awm?
• Cancer hi eng stage/grade nge ni?
• Chu stage/grade chuan engtin nge ka treatment plan chu a nghawng?
• Eng treatment side effect nge ka beisei ang?
• Ka cancer hi a dam thei ang em?
• Enkawlna tumte chu engte nge ni?
• Ka cancer hmuhchhuah tawhna ka hmachhawn theih nan palliative care services te nen min inzawm tir thei ang em?

Spindle cell sarcoma hi tihdam theih a ni em? Engtiang chiahin nge a serious?

Cancer hnuhma zawng zawng chu paih vek theih a nih chuan doctor-te chuan spindle cell sarcoma hi an tidam thei ang. Spindle cell sarcoma a awmna hmun atanga lo darh lo chu tihdam a awlsam zawk hle. Mahse, sarcomas darh tawh enkawl chu a harsa hle . Metastatic Spindle Cell Sarcomas hi tihdam theih a ni lo.

Hetiang cancer hi ‘high-grade’ a ni fo thin. Chumi awmzia chu a thang chak a, a darh chak tihna a ni. Remission hnuah chuan a lo let leh mai thei a, a chang chuan a bul tanna hmun khatah a awm a, a chang chuan hmun dangah a lo lang leh thin.

Mahse, cancer hmuhchhuah apiang hi a danglam vek tih hre reng ang che. I doctor chuan cancer chi khat bik, a stage, i hriselna zawng zawng, enkawlna i dawn dan leh thil dang hrang hrang a zirin enkawlna (prognosis) atanga i chhuah theih dan tur a hrilh thei che a ni. He diagnosis hian engtin nge a nghawng ang che tih hi i doctor hi a ni.

He thawnthu atang hian kan hriat reng tur thil (Take-Home Message) .

Spindle Cell Sarcoma vei nia hriat chu thil lungchhiatthlak tak a ni thei. Chu dinhmun chuan i chau thei a, i rilru a hahdam lo thei bawk. Enkawlna hi a nasa fo thin a, ruh graft emaw, kut leh ke siam emaw hman thiam ang chi harsatna i tawk thei bawk.

Chuvang chuan a tir a\angin doctor nen rinawm tak leh inhawng taka inbiakna neih a pawimawh hle. Chutiang chuan i natna hmuhchhuah dan te, i cancer tihdam theihna tur te, i enkawlna tumte chu eng nge ni tih te, leh enkawlna leh dam leh hun chhunga nunphung tihdanglam i mamawh tur te chu i hrethiam thei ang.

Spindle cell sarcoma hi cancer na tak, a lo thang chak hle a ni. Mahse, a thanna thunun thei leh, a then phei chuan a tidam vek thei damdawi a awm. I beisei theih turte chu i doctor nen sawiho rawh. Beiseina chu bansan ngai suh. He inbeihnaah hian damdawi lam thurawn dik zawm leh positive taka awm hi a pawimawh hle.

Spindle Cell Sarcoma, Spindle Cell Sarcoma, Cancer, Ruh Cancer, Soft Tissue Cancer, Tumor, Symptoms, Enkawl dan