I thisenah lymphocyte i tlem em? Lymphopenia chungchang hi han sawi ila!

I damlo fo em? A châng chuan khawsik tê tê pawh hian a dam theih nân hun rei tak a la ngai a, a nih loh leh i chak lo tih i inhriat reng em? Heng thilte thlen chhan pakhat chu thisen var chi khat lymphocyte an tih tlahniam vang a ni thei a, chu chu i taksaa natna dotu sipai ang mai a ni. Doctor-te chuan he natna hi ‘lymphopenia’ tiin an sawi. Chuvangin, vawiin hian he thu hi chipchiar deuhin han sawi ila, kan sawi dawn em ni? Hlauh tur a ni lo, fimkhur a pawimawh.

Lymphopenia chu eng nge ni? A awlsam zawngin i hrethiam ang u!

A awlsam zawngin sawi ila, lymphopenia hi i thisena lymphocyte awm zat chu a tlangpui aia tlem a ni. Tunah chuan heng lymphocyte te hi eng nge an nih i ngaihtuah mai thei.

Kan thisenah hian thisen var chi khat a awm a. Chu thisen var te chu kan taksaa lut hrik, chu chu natna thlentu bacteria leh virus te do a, min vengtu an ni. Kan taksaah sipai tlemte ang mai a ni. Heng thisen var zinga 20% leh 40% inkar hi he cell chi bik Lymphocytes an tih hi a ni.

Heng lymph cells (Lymphocytes) te hnathawh ber chu:

• Taksa chhunga lut natna hrik (virus, bacteria, parasite, fungi) dona.
• Cell pangngai lo, cancer cell ang chi tihchhiat.
• Kan taksa immune system-a thil pawimawh tak anga thawk.

Lymphocyte hi chi thum a awm a, chungte chu:

• T-lymphocytes emaw T-cells: Hengte hian hri kai cell leh cancer cell te chu direct-a tihchhiat nan a pui thin.
• B-lymphocytes emaw B-cells emaw: Hengte hi antibodies siamtu an ni. Heng antibodies te hian natna hrik hriatchhuah leh beihpui thlakna kawngah a pui thin.
• Natural Killer cells (NK cells): Hengte hian virus kai cell leh cancer cell te tihchhiatnaah pawh a pui bawk.

Chuvangin, lymphocyte a tlem chuan, chu chu lymphopenia an tih dinhmun a lo awm chuan kan taksain natna a do theihna a tlahniam a ni. Tichuan, natnate chu awlsam takin a lo awm thei a, natna lo awm tak takte chu a dam rei thei hle.

Lymphopenia hi lymphocytopenia leh lymphocytic leukopenia tia hriat a ni bawk. Leukopenia tih hian a tlangpuiin thisen var tlahniam tihna a ni. "Lymphocytic" leukopenia tih hian a bik takin lymphocyte tlahniam tihna a ni.

A tlangpuiin lymphocyte engzat nge awm tur?

Heng lymph cells (Lymphocytes) te hi puitling leh naupang zingah a inang lo hle.

• Puitlingah: A tlangpuiin thisen microliter khatah lymph cell 1,000 leh 4,800 inkar a awm tur a ni. Lymphopenia chu he zat hi 1,000 aia tlem a nih chuan a ni.
• Naupangte tan:A tlangpuiin thisen microliter khatah lymphocyte 3,000 leh 9,500 inkar a awm thin. Hetiang level hniam hi naupang kum a zirin a danglam thei. Entirnan, naupang kum 2 hnuai lam pakhatin lymphocyte count 3,000 aia tlem a neih chuan lymphopenia anga ngaih a ni.

Heng value te hi lab hrang hrangah a inang lo deuh thei a, chuvangin i report-a average value te nen khaikhin a tha ber.

Lymphopenia natna lan chhuahna chu engte nge ni?

A tha ber chu lymphopenia chauh i neih chuan, chu chu lymphocytes tlakchham tihna a ni a, symptoms i nei lo fo thin. Mahse, lymphocyte count tlahniam chhan natna hnuaia awm a awm chuan chu natna nena inzawm symptoms i nei thei a ni. A nih loh leh natna hrik i nei fo thei bawk.

A lan chhuah dan thenkhat chu:

• Khawsik
• Khuh
• Hnar luang chhuak
• Skin rash emaw vun allergy dang emaw a awm thei
• Lymph node a lo hring chhuak
• Joint swelling a awm
• Kawngkhar natna
• Mit leh vun sen (Jaundice) .
• Spleen lian emaw, splenomegaly emaw a awm

Lymphopenia na tak i neih chuan natna hrik i kai fo thei a, natna hrik i dam theih nan hun rei tak a la ngai thei bawk. Mahse, lymphopenia na lo tak nen chuan symptoms i nei lo mai thei.

Engvangin nge heng lymphocyte count te hi a tlahniam? A chhante chu engte nge ni?

Lymphocyte hniam i neih theihna chhan hrang hrang a awm thei. A châng chuan he natna thlentu natna neia piang i ni thei bawk. A nih loh leh, nakin lawkah a lo thang lian thei bawk. A chhan azirin lymphopenia hi dam chhung (chronic) emaw, a takin a reh thei (acute) emaw a ni thei.

Lymphopenia thlentu ber thenkhat chu natna hrik, damdawi thenkhat, leh ei leh in lama harsatna te hi a ni.

1. Infection vangin

Virus, bacteria, parasite, leh fungi avanga natna hrik kai hian lymphocyte a tihhniam thei a ni. Entirna tlemte chu hetiang hi a ni:

• `HIV` leh `AIDS` tih te a ni
• Influenza (flu) - chu chu, tawng tlangpuiin, flu tihna a ni.
• `COVID-19` tih a ni
• Hepatitis - thin natna a ni
• Malaria natna a awm
• Measles natna a ni
• Pneumonia natna (Pneumonia) a ni
• Tuberculosis natna a ni

Chutiang infection a lo thlen chuan taksaa lymph cells (Lymphocytes) te chu do turin a tichhia thei a, a nih loh leh an siamchhuahna chu rei lo te chhungin a titawp thei bawk.

2. Nutritional Deficiency vangin

Hei hi khawvel puma lymphopenia thlentu lian ber a ni. I ei leh in atang hian a tawk tawk la.Malnutrition emaw, vitamin B12, folic acid emaw zinc ang chi vitamin leh mineral tlakchhamna hian lymphocyte siamchhuahna a tichhe thei a ni. Kan nunphung buaithlak tak tak nen hian a chang chuan kan ei leh in hi kan ngaihven tawk lo. Hetiang thil hi a kal zel chuan hetiang dinhmun hi a thleng thei a ni.

3. Inherited Conditions avang hian

Nu leh pa atanga fate hnena kai theih genetic diseases hmuh tur awm lo thenkhat a awm bawk. Heng natnate hian lymphocyte a tihhniam phah thei bawk. Entirna thenkhat:

• `Ataxia-telangiectasia awm thei te hi a ni`
• ``Common variable immunodeficiency a awm fo thin''.
• `DiGeorge natna a ni` tih hi a ni
• ``Severe combined immunodeficiency syndrome (SCID) tih a ni a, a rilru a hah lutuk a, a rilru a buai em em bawk a.
• `Wiskott-Aldrich natna` tih a ni

Hengte hi a buaithlak deuh a, mahse hengte hi thil awmdan a tlem hle.

4. Autoimmune Diseases vang a ni

Autoimmune diseases chu keimahni immune system, natna laka min vengtu system-in kan cell hrisel tak takte a rawn beih palh hi a ni. Ngaihtuah teh, i taksa invenna system chu a kal lo va, a cell tha tak takte chu a do tan ta a ni. Chu chu hei hi a ni. Lymphocytes hi cell beitu zingah hian a tel thei a ni.

Chutiang natna thenkhat chu:

• Lupus a ni
• Sarcoidosis natna (sarcoidosis) a ni
• Myasthenia gravis natna (myasthenia gravis) a ni
• Rheumatoid arthritis - chu chu ruh natna tihna a ni

5. Thisen lama harsatna leh Cancer vangin

Thisen chhunga cell dang ang bawkin ruhro (bone marrow)-ah hian lymphocyte siam a ni. Chuvangin, thisen natna leh cancer te hian ruhro a tichhe thei a, lymphocyte siamchhuahna a tichhe thei a ni.

• Aplastic anemia - ruhro hian cell tlem zawk a siam chhuak thin
• Lymphoma - thisen zam natna (lymphatic system) cancer a ni
• Leukemia - thisen cancer a ni
• Myelodysplastic syndromes te hi a awm a

6. Damdawi leh Enkawlna Side Effects angin

Lymphocytes hi a tlahniam thei a, a bik takin cancer enkawlna leh autoimmune natna damdawi thenkhat avang hian a tlahniam thei a ni.

• Bone marrow thlak danglam a ni
• Chemotherapy hmanga enkawl a ni
• Radiation hmanga enkawlna a ni
• Immunosuppressant - entirnan, corticosteroid te hi a tha hle.

7. Zu Toxicity vangin

Zu in tam lutuk (beer, wine, leh zu ang chi) hian lymphocyte te pawh a nghawng tha lo thei a, an tamna a ti tlem thei bawk.

Engtin nge lymphopenia i vei tih i hriat theih ang?

Lymphopenia i vei nia i rinhlelh chuan doctor pan a, sawipui a tha ber. Doctor chuan i damdawi lam chanchin, tuna i natna lan chhuah dan leh i nunphung te a zawt ang. Chumi hnuah chuan test thenkhat an run mai thei.

Doctor endik leh zawhna zawh a ni

• Medical history: I doctor chuan i medical history kal tawh te, tuna i damdawi hman mek te leh i enkawl dan te a zawt ang. Entirnan, tun hnaia COVID-19 i vei a nih chuan i doctor chuan virus infection vangin i lymphocyte count a tlahniam niin a ngai mai thei. Corticosteroid ang chi damdawi i ei a nih chuan chu pawh chu a chhan a ni thei bawk.
• Taksa enfiah: Doctor chuan i natna lan chhuah dan a zawt ang a, khawsik, lymph node hring, leh i rilru a lian tih te a enfiah ang.
• Nunphung zawhna: I ei leh in chungchang zawt chein ei leh in lama harsatna i neih leh neih loh en theih a ni. HIV ang chi natna hrik i neih loh nan i sex life (damdawi him i hman leh hman loh ang chi) pawh zawh i ni thei bawk.

Eng test nge tih thin?

Thisen cell leh ruhro enfiahna test eng emaw zat a awm a.

• Complete Blood Count (CBC): Hei hian i thisen chhunga cell chi hrang hrang (thisen var te pawh tel) zat a chhiar a ni.
• Complete blood count with differential (CBC with differential): Hei hian thisen var chi hrang hrang (platelet telin) a hranpaa chhiar a ni.
• Flow cytometry: Hei hi test bik deuh a ni. Lymphocyte subtype hrang hrang, B cells, T cells, leh NK cells te chu a hranin a teh thei a ni.
• Immunoglobulin level test: Hei hian i thisena proteins antibodies an tih zat a teh a. Lymphopenia nena inzawm natna tam tak, infection, autoimmune diseases, leh cancer te hriatchhuahna kawngah a pui thei a ni.
• Bone marrow analysis: Hei hi mi zawng zawng tan tih a ni lo a, mahse lymphocyte siam chhuahnaah harsatna lian tak a awm nia rinhlelhna a awm chuan i doctor chuan he test hi a rawt thei ang.

Tin, natna chi hrang hrang, lymphopenia thlentu (HIV test, tuberculosis test, flu test, emaw COVID-19 test ang chi) enfiah nan test dang pawh tih theih a ni bawk.

Lymphopenia enkawlna tur hi engte nge ni?

In most cases , lymphopenia na lo tak, a bik takin a lan chhuah loh chuan enkawlna bik a ngai lo. Infection ang chi thil avanga lo awm a nih chuan taksain a dam leh hunah lymphocytes zat chu a pangngaiin a kir leh ang.

A pawimawh ber chu lymphopenia hi a chhan bulpui enkawlna hmanga enkawl a ni.

I lymphocyte tlahniam chhan a hriat hnuah i doctor chuan enkawlna dik tak a pe ang che.

Lymphopenia hi a dam kim thei ang em?

Lymphocyte siam that theih lohna tur genetic condition neia piang i nih chuan hematopoietic stem cell transplant an tih enkawlna hi a chang chuan damdawi a ni thei. Hei hian thisen siamtu stem cell chhia emaw, chhia emaw paih chhuah a, stem cell hrisel tak takte thlak a huam a ni. Chumi hnuah chuan heng cell tharte hian lymphocytes an siam chhuak a, chubakah thisen cell dangte pawh an siam chhuak bawk.

Mahse, hei hi enkawlna a buaithlak deuh a, a hlauhawmna a awm bawk. Hetiang hi mi zawng zawngin an ti thei vek lo. Hei hi i tan a tha em tih i doctor chuan a hrilh ang che.

Damdawi enkawlna atana hman thin

Lymphopenia na tak i neih chuan, chu chu natna kai fo tihna a ni a, i doctor chuan immunoglobulin (IG) shot a pe thei che a ni . Heng shot te hian i immune system a tichak a, infection dona kawngah a pui bawk. Tin, hri kai tam loh nan heng IG shot te hi ei chhunzawm zel turin hriattir i ni thei bawk.

Lymphopenia hi ven theih a ni em?

Genetic cause avanga lymphopenia lo awm chu ven theih a ni lo. Mahse, thil dang avanga lymphopenia i vei theihna tur tihtlem nan thil engemaw i tih theih a awm a:

• Natna hrik laka invenna: Natna thlentu hrik laka inven nan theihtawp chhuah thin ang che.
• Sex hman dan him: HIV ang chi sexually transmitted infection (STI) laka inven nan hmanraw him zawm tur a ni.
• Zu control: Zu i in chuan khap tlat ang che. Ni khatah beer can khat aia tam, wine glass khat, zu shot khat aia tam in loh a tha ber.

Lymphopenia i neih chuan engtin nge natna hrik lakah i inven theih ang?

I lymphocyte count a hniam chuan natna hrik laka inven a pawimawh. Hengte hi a pui thei tur thil thenkhat chu a ni:

• Vaccine lak: Flu leh COVID-19 vaccine lak. I doctor hnenah vaccine dang zawt rawh.
• Hri kai theihna hmun tamna hmunah pumpelh rawh: Damlo emaw, damlo thei emaw lakah inthiarfihlim rawh. Indoor space-a mipui tamna hmun, boruak luh that lohna hmuna inhriatthiam lohna tihtlem.
• Kut sil fo tur: Sahbawn leh tui hmangin i kut sil fai la, a nih loh leh zu hmanga siam hand sanitizer hmang bawk ang che.
• Mask vuah: Thli atanga virus awm theihna hmuna kal dawnin mask vuah tur a ni.
• Chaw him: Chaw chu uluk takin chhum rawh. Thlai leh thei chi hrang hrangte chu ei hmain uluk takin silfai thin ang che.
• Hliam pumpelh rawh: Hliam hrual leh hrual ang chi hian taksaah natna hrik a luhtir thei a, chuvangin chutiang accident lakah fimkhur rawh.

Hei bakah hian i doctor hnenah a bik taka fimkhur tur thil a awm leh awm loh zawt la.

Lymphopenia vei te hriselna dinhmun hi eng nge ni? (Outlook/Prognosis) tih a ni.

Hei hi i lymphocyte tlahniam chhan ah a innghat vek a ni. A tlangpuiin, a tlahniam chhan chu infection vang a nih chuan, infection a dam hnuah lymphocyte count chu a normal leh ang. Amaherawhchu, a chhan lian zawk vang a nih chuan a enkawl dan chu a rei deuh thei a, a buaithlak zawk bawk.

Doctor hmuh hun tha ber berte chu engte nge ni?

Infection chhinchhiahna (khawsik, khuh, taksa na ang chi) i neih chuan doctor pan nghal rawh. Hri kai tam theihna tur (lymphopenia ang chi) i neih chuan i doctor hnenah eng symptom nge i lak tur tih zawt hmasa phawt ang che.

Lymphopenia hi cancer a ni em?

Ni lo, lymphopenia hi cancer a ni lo. Mahse, cancer chi thenkhat (e.g. leukemia, lymphoma) hian lymphocyte siam chhuahna a tibuai thei a, lymphopenia a thlen thei a ni. Tin, cancer enkawlna thenkhat (chemotherapy ang chi) hian hun engemaw chen atan lymphocytes level a tihhniam thei bawk.

Take-Home Thuchah a ni

Okay, chuti a nih chuan tunah chuan vawiin a kan sawi tawh, Lymphopenia kha i hrethiam zawk tawh ang. Hrereng:

• Lymphopenia hi thisenah natna dotu cell chi khat lymphocytes tlahniam a ni.
• Hei hi thil dang mai a ni lo va, natna hrik emaw, ei leh in lama harsatna emaw, damdawi pakhat avanga side effect emaw, damdawi lam thil dang emaw nen a inzawm fo thin.
• A tam zawkah chuan mild case-ah chuan symptoms a lang lo.
• I damlo fo a nih chuan, emaw, he thil chungchangah hian rinhlelhna i neih chuan, a tha ber chu doctor pan a, thurawn lak hi a ni.
• A chhan hmuhchhuah a nih a, uluk taka enkawl a nih chuan he natna hi control theih a ni fo.

Chuvangin, i hriselna hi uluk takin enkawl rawh. Zawhna i neih chuan Doctor nen inbiakna neih hlau suh. Hrisel takin awm rawh!

` Lymphopenia, lymph cell, lymphocyte, thisen var, immunity, natna hrik, symptoms te