Hliam te tak te emaw, scrape emaw i neih chuan eng nge thleng? Rei vak lo hnuah thisen chhuak chu a reh ta a ni lawm ni? Chu chu kan taksaa defense mechanism mak tak avang a ni. Chu chu " thisen zam " kan tih chu a ni. Mahse, he process hi a thawk tha lo a nih chuan eng nge thleng ang tih han ngaihtuah teh? Thisen chhuahna chu tihtawp theih a ni lo emaw, taksa chhungah chhan awm lovin thisen zam a lo awm emaw a ni thei. Chu chu damdawi lama coagulation defect kan tih chu a ni. Vawiin hian he thu hi awlsam takin, i hriatthiam theih angin kan sawi dawn a ni.
A awlsam zawngin, he thisen zam hi eng nge ni?
Hei hi hriatthiam a awl hle mai. I thisen kalna kawngte chu tui phurtu pipe angin ngaihtuah rawh. He pipe-ah hian khur te tak te a awm chuan (i.e., hliam a awm chuan), thisen chu tui leak ang maiin a chhuak ang. Hetiang hunah hian kan taksa hi a fing hle. Rang takin "repair team" chu a hmunah a tir ta a ni.
He pawlah hian member lian pahnih an awm a.
- Platelets : Hei hi kan thisena cell te tak te chi khat a ni. Plaster hmasa ber, khur khuh tu ang mai an ni.
- Coagulation Factors: Hengte hi thisen chhunga protein bikte an ni. Chu plaster chunga cement layer nghet tak i dah ang mai an ni.
Heng platelet leh clotting factors te hian an thawk dun a, hliamna hmunah thisen zam chak tak an siam a, thisen chhuah chu a titawp a ni. Hliam a dam hnuah taksa chuan a hmin a, he thisen zam hi a paih chhuak ta a ni .
Chuvangin, thisen zam natna (blood clotting disorder) tih awmzia chu he repair team (platelets emaw clotting factors) te harsatna avang hian thisen zam (blood clotting process) a awm tha lo tihna a ni.
Heng chak lohnate hi chi hnih ah then theih a ni:
He harsatna hi kawng lian pahnihin a lo awm thei a ni. Chu chu thisen zam chu a tul aia a tlahniam a, a tul aia tam a pung tihna a ni. Hei hi a hnuaia table-ah hian sawifiah belh leh ila.
| Chak lohna awmzia | Damdawi lam hming | A awlsam zawngin, eng nge thleng? |
|---|---|---|
| Thisen zam a tlahniam | Hemorrhaging (thisen chhuak tam lutuk) . | A tlangpui aia rei thisen chhuak. Hliam te tak te pawhin taksa atangin thisen tam tak a luang chhuak thei a ni. |
| Thisen zam a tipung | Thrombosis (Thrombosis) a awm thin | Thisen kalna kawng hrisel chhungah hliam awm lovin duh loh zawng thisen zam a lo awm a, thisen kal dan a tikhawlo. |
Heng dinhmunte hi eng chhan nge ni?
Hetiang thisen zam natna hi chhan hrang hrang a awm a. Ṭhenkhat chu kan pianpui (inherited) genetic conditions an ni . Midangte chu kan dam chhungin natna dang emaw, dinhmun dang emaw avanga kan neih theih a ni.
Heng chi hrang hrangte hi eng chhan ber nge ni tih i lo en ang u.
| Chhan | A sawifiahna awlsam tak |
|---|---|
| Thisen zam (thisen chhuak) tlahniam chhan . | |
| Hemophilia (Hemophilia A, B, leh C) te hi a ni. | Hei hi a bik takin inherited genetic disease a ni. Hetiang dinhmunah hian taksain thisen zamna atana thil pawimawh thenkhat a siam chhuak lo. |
| Von Willebrand natna a ni | Hei pawh hi thlahtu (hereditary condition) a ni bawk. Hetiang dinhmunah hian taksaah hian protein pakhat von Willebrand factor a tlachham a, chu chuan thisen a tikhawlo thei a ni. |
| Liver Natna a awm | Kan taksa mamawh clotting factors tam zawk hi liver hian a siam chhuak thin. Thin natna a awm chuan he production hi a tichhe thei a, thisen zam a tlahniam thei bawk. |
| Vitamin K tlakchhamna | Vitamin K hi thisen zam nana vitamin pawimawh tak a ni. A hniam chuan thisen chhuah tihtawp a harsa thin. Hei hi naute hnute chauh pek zingah a langsar hle. |
| Thisen zam tamna chhan (Thrombosis) . | |
| Factor V Leiden chuan a rawn ti a | Hei hi genetic condition a ni bawk a, thlah khat atanga thlah dangah a kal zel a ni. Chutiang a nih chuan clotting factor (Factor V) chu a thawk nasa lutuk a, a tul lova thisen zam a siam thin. |
| Prothrombin Gene a inthlak danglam thin | He genetic change hian taksaah clotting factor dang, ‘prothrombin’ a siam tam lutuk a ni. |
| Antiphospholipid Antibody Syndrome natna a awm thei | Hei hi autoimmune natna a ni. Chumi awmzia chu taksa invenna (defence system) hian a cell-te a bei tihna a ni. Hei hian duh loh zawnga thisen zam a tipung a ni. |
Heng natna lan chhuah dante hi engte nge ni?
Thisen zam tlem leh sang chi i neih leh neih lohah hian symptoms a innghat a ni.
Thisen zam tlahniam chhinchhiahna
- Bruising easily: Bump tenau tak hnuah blue a lo chang.
- Hnar thisen chhuak tam : Chhan hriat loha hnar thisen chhuak fo.
- Zun chhunga thisen: I zun chu a sen, a sen, a sen emaw a nih chuan.
- Hliam tawp lo atanga thisen chhuak: Hun rei tak chhung thisen chhuak , a hliam tenau atanga thisen chhuak.
- Chauhna nasa tak a awm.
- Hmeichhe thenkhat chuan thlasik laiin thisen chhuak nasa tak an nei thin.Thisen chhuak .
Thisen zam tamna (Thrombosis) chhinchhiahna .
A natna lan chhuah dan chu thisen zam awmna hmun a zirin a ni. Hengte hi dinhmun hlauhawm tak tak a ni thei.
- Heart Attack: Thisen zawnin coronary artery a block chuan rilru natna leh thawk harsa tih ang chi symptoms a awm thei.
- Stroke: Thisen zam hian thluaka thisen petu thisen kalna kawng a block chuan taksa sir khata chak lohna, tawng harsa, leh hmai tlakchham ang chi symptoms a awm thei.
- Pulmonary Embolism : Thisen zam, thisen zam (vein)-a lo awm, lung chhunga thisen phurtu. A lan chhuah dan chu thawk hah thut leh rilru natna te a ni.
- Deep Vein Thrombosis (DVT): Thisen zam hi kea vein lian takah a lo awm tlangpui. A lan chhuah dan ber chu ke hring, sen, leh ke natna te hi a ni .
Hei hi eng enkawlna nge ni?
I doctor chuan eng enkawlna nge i tana tha tur tih a rel ang. I natna chhan bulpui leh i natna nasat dan ang chi thilah a innghat a ni. Thil na lo thenkhatah chuan enkawlna bik a ngai lo mai thei.
Enkawl dan tlangpui thenkhat chu hetiang hi a ni:
- Damdawi: Thisen zam tamna nei te chu thisen tithianghlimtu, ``Warfarin`` emaw ``Heparin emaw pek an ni.`` Thisen zam hniam nei tan pawh a kalphung pui thei damdawi a awm bawk.
- Factor Replacement Therapy: Hei hian taksaa clotting factors awm lote chu injection hmanga taksaah direct-a pek a ni. Hei hi hemophilia ang natna nei tan chuan a pawimawh hle.
- Thisen pek: Thisen chhuak tam lutuk a awm tawh chuan thisen bo thlak nan pawn lam thisen pek a ngai mai thei.
- Enkawlna dang: A chang chuan vitamin K tlakchhamna hi a chhan bulpui enkawlna hmanga control theih a ni a, chu chu vitamin K pek emaw, thin natna enkawl emaw a ni.
A pawimawh ber chu, i rilru put hmang emaw, mi dangin an hrilh che emaw a zirin heng natnate damdawi hi kal ngai suh. Doctor thiam tak thurawn zawm fo ang che.
Thisen chhuak nasa tak, hliam na tak tak, a chunga kan sawi tawh ang chi i neih chuan doctor pan ngei ngei tur a ni.Hemi chungchang hi sawi rawh. Tin, thisen zam natna (rilru na nghal, taksa sir khata chak lohna, thawk harsa) i neih chuan damdawi in Emergency Department (ETU) ah tihkhawtlai lovin kal rawh. I nunna a chhanhim thei a ni.
Take-Home Thuchah a ni
- Coagulation defects hi chi hnih a awm a, chungte chu hypocoagulation (thisen tam lutuk) leh hypercoagulation (a tul lo taka thisen zam siam) te an ni.
- Heng dinhmunte hi pian tirh atanga lo awm thin genetic cause emaw, dam chhunga natna dang lo awm vang emaw a ni thei.
- Thil chi hrang hrang, hliam awlsam tak, hnar thisen chhuak fo, leh thisen chhuak, hliam tenau tak atanga tihtawp theih loh te hi fimkhur rawh.
- Simptoms, rilru na thut, thawk harsa, taksa sir khata chak lohna te hi thisen zam chhinchhiahna hlauhawm tak a ni thei. Chutiang a nih chuan damdawi in pakhat Emergency Department (ETU) ah kal nghal mai tur a ni.
- Hemi chungchangah hian rinhlelhna i neih chuan i chhungkaw doctor rawn la, thurawn la rawh.
👩🏽 ⚕️ Zawhna dang (FAQ)
💬 🖐️ Engvangin nge ka kutphah chu a sen? (Engvangin nge ka kutphah hi a sen?)
Kutphah hi a sen a nih chhan lian tak tak engemaw zat a awm. A tam zawkah chuan carrot leh pumpkin (Carotenemia) ang chi ei tam lutuk hian hetiang hi a thleng thei. Mahse, kutphah pawh hi jaundice vei a nih chuan a sen a ni a, hei hi thin natna avanga lo awm a ni. Chuvangin hemi chungchangah hian tlem tal i fimkhur a ngai a ni.
💬 🩸 Kut sen hring leh thisen zam harsatna (Coagulation defects) hi eng nge inzawmna?
An pahnih inkarah hian inzawmna lian tak a awm. Kan thisen a clotting factors tam zawk hi liver atanga siam a ni. Chuvangin thin a chak lo a, kutphah a sen chuan thisen zam harsatna a awm thei bawk. Chumi awmzia chu thin (liver) a damloh chuan thisen a khai tha lo tihna a ni.
💬 🤔 Ka kutphah a sen a, thisen a chhuak a nih chuan ka lungngai tur em ni?
Ni e, i kutphah a sen a, hnar thisen chhuak, hmui thisen chhuak emaw, hliam tenau tak nei pawhin awlsam taka i hliam emaw a nih chuan coagulation defect a ni thei. Chutiang hunah chuan doctor pan vat a, i thin (liver) enfiah tir a pawimawh hle.
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