Kua rongo koe i te acetylcholine , te (ACh) rānei? Tērā pea kua kōrerotia e tō tākuta ki a koe, kua pānuitia rānei e koe i tētahi wāhi. He matū iti engari he mea nui rawa atu i roto i tō tātou tinana. He rite ki tētahi kaimahi mēra iti e kawe ana i ngā karere i roto i tō tātou tinana. Nō reira, i tēnei rā ka kōrero tātou mō te acetylcholine i tētahi ara māmā ka taea e koe te mārama.
He aha rawa te Acetylcholine?
He whakarāpopototanga noa iho, he neurotransmitter te acetylcholine. Whakaarohia, me tuku karere hiko iti tō roro hei neke i tō ringa, hei whakaaro, hei maumahara ki tētahi mea, ki ēnei mea katoa. He matū karere te acetylcholine e āwhina ana ki te kawe i aua karere mā roto i ngā pūtau io .
Ka kiia hoki tēnei he neurotransmitter " whakaoho " . E mōhio ana koe he aha tēnā? Ka "whakaara" i tētahi pūtau io, arā, ka whakaoho i a ia, ā, ka tere ake tana "tuku" karere. He rite ki te patuki i te tatau o tētahi tangata e moe ana, ka mea, "Anei, tangohia tēnei reta."
Ko te ingoa acetylcholine i ahu mai i ngā mea e rua e hanga ana i tēnei. Ko tētahi he rōpū acetyl . I ahu mai tēnei i tētahi matū e kiia nei ko te acetyl coenzyme A, i hangaia mai i te huka hukahuka. Ko tētahi atu he matūkai e kiia nei ko te choline . Ka kitea noa te choline i roto i ngā toene hua manu, te pīni soya, te ate, ngā huawhenua, me ngā pīni. Ka hangaia hoki te choline i roto i tō tātou ate.
He maha ngā mahi nui a te acetylcholine i roto i te tinana, inā koa ko te nekehanga o ngā uaua tūao.He mea nui tēnei i roto i ā tātou mahi hinengaro, pērā i te neke i ō tātou waewae me te hikoi. Ka whakaoho i ngā pūtau io i roto i ō tātou uaua, ka meinga kia kōpiri. Ehara i te mea koinā anake, engari he mea tino nui anō hoki mō ngā pūtau io i roto i tō tātou roro, me ngā tukanga pērā i te mahara, te whakaaro, me te ako.
He pēhea te mahi a te acetylcholine (ACh)?
Kei ngā pito o ngā pūtau io te acetylcholine e rongoa ana, kia tae rā anō ki te wā e hiahiatia ana te tuku karere. Ina tae mai he "tohu" hei tuku karere, ka tukuna tēnei acetylcholine kua rongoatia. Kia tukuna, ka haere ki roto i tētahi āputa iti i waenganui i ngā pūtau io e rua. Ka kiia tēnei āputa ko te kapiti synaptic .
I muri i te whiti i te kapiti synaptic, e rua ngā momo kaiwhakawhiwhi ka taea e te acetylcholine te here ki. Ko ēnei:
- Ngā kaiwhakawhiwhi nikotīni
- Ngā kaiwhakawhiwhi muscarinic
I muri i te herenga ki ēnei kaiwhakawhiwhi, ka haere te karere matū ki te pūtau io e whai ake nei. I muri i te tukunga o te karere, kāore te acetylcholine e toe ana i roto i te kapiti synaptic e maumau noa. Ka puta mai tētahi atu whākōkī e kiia nei ko te acetylcholinesterase , ka wawahi i tēnei acetylcholine ki roto i ōna wāhanga, arā, ko te choline me te acetate. Kātahi ka mimitihia anō ēnei wāhanga pakaru, ka hangarua, ka whakamahia hei kawe i tētahi atu karere matū. He pūnaha tino whai hua!
He aha te mea ka pā ki te acetylcholine (ACh)?
He maha ngā painga o te acetylcholine mō ō tātou tinana. Me titiro tātou ki ngā mea matua.
| Momo kaiwhiwhi | Ngā mahi matua |
|---|---|
| Ngā kaiwhakawhiwhi muscarinic |
|
| Ngā kaiwhakawhiwhi nikotīni (Nikotini) |
|
E rua ngā momo kaiwhakawhiwhi e whai wāhi ana ki roto i tō tātou mahara . Arā, he mea nui rātou mō te mahara roa, te mahara poto, te hanganga o ngā mahara, te whakakotahitanga, me te whakahokinga mai. I roto i te roro, kei roto te acetylcholine i ētahi atu mea. Ka whakatairanga i te hihiri, te hiahia/te aro, te ako, me te moe REM (te wāhanga o te moe e moemoeā ana tātou).
He aha ngā āhuatanga ka puta ina heke te taumata o te acetylcholine (ACh)?
Ka taea e te iti o te taumata o te acetylcholine, te kore rānei, te arahi ki ētahi mate. Ko ngā mea tino nui o ēnei ko:
- Te mate a Alzheimer : Kāore i te nui te acetylcholine i roto i te roro o te hunga e pangia ana e te mate a Alzheimer. Nā reira, ko te ngaronga o te mahara te tohu nui.
- Te mate myasthenic Lambert-Eaton : Ka puta tēnei mate i te hekenga o te tukunga o te acetylcholine mai i ngā pūtau io.
- Myasthenia gravis : He mate pūnaha ārai mate tēnei e ngoikore tere ai ngā uaua angiangi i muri i te whakamahinga tonu.
He mea nui:Ki te pā mai tētahi o ēnei tohu ki a koe, me toro atu ki te tākuta tonu. Kaua e tātaritanga i a koe anō.
He aha ngā rongoā e aro ana ki te acetylcholine (ACh)?
Ko ngā aukati cholinesterase he momo rongoā e mahi ana mā te whakakore i te whākōkī e wawahi ana i te acetylcholine me te whakanui ake i te mahi a ngā kaiwhakawhiwhi acetylcholine. E whakamahia ana ēnei hei rongoā i te mate a Alzheimer me te myasthenia gravis. Ko Donepezil (Aricept®), Rivastigmine (Exelon®), me Galantamine (Razadyne®) ētahi o ēnei rongoā.
He aha ngā kai kei roto te choline, e āwhina ana ki te whakaputa acetylcholine (ACh)?
Ko te Choline, he matūkai ka huri hei acetylcholine, kei roto i te maha o ngā kai. Hei tauira:
- Ate kau
- Ngā hua manu (ina koa ko ngā toene)
- Pīhi kau porotaka
- Pīni pīni tunua, pīni whatukuhu kēne
- Uma heihei tunua
- Ika kōtare `(Kōtare)`
- Quinoa kua tunua
- Harore shiitake kua tunua, te pūrokoro kohuatia me ngā pihi Brussels
- Miraka (1%) `(Miraka (1%))`, miraka kawa vanilla kore ngako `(miraka vanilla kore ngako)`
Whakamātauria te tāpiri i ēnei kai ki tāu kai. He mea tino nui te kai taurite mō te oranga hauora.
Karere Tangohia ki te Kāinga
Nā, kua mārama pea koe ināianei ko te acetylcholine (ACh) he neurotransmitter e tino hira ana mō te mahi a tō tātou roro, te mahara, me ngā mahi a te tinana pērā i te whakaheke uaua. Mēnā ka heke ōna taumata, ka puta pea ngā raruraru mahara me ngā mate e pā ana ki ngā uaua. Ko te mea nui, ki te pāngia koe e ētahi raruraru hauora, kōrero ki te tākuta mō tēnei mea. Kaua e haere ki te maimoatanga i runga i ngā whakapae noa. Kia ora tonu!
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