He raruraru nui kei te pā ki te tini o te tangata i Sri Lanka ko te toto toto tiketike. Ki ētahi, he tino uaua ki te whakahaere i tēnei ahakoa kua tangohia he rongoā. Engari kei roto i ō tātou tinana tētahi tangata kāore tātou e kōrero nui mōna, engari he mea huna e awe ana i te toto toto. Koinei te mea ka kōrerohia e tātou i tēnei rā. Ko Aldosterone tōna ingoa.
Hei whakarāpopototanga, ko wai tēnei aldosterone?
He homoni te Aldosterone i roto i tō tātou tinana. He rite ngā homoni ki ngā kaikawe mēra i roto i tō tātou tinana. Ka haria e rātou ngā karere ki ia okana, e kī ana kia mahi i tēnei, kia mutu i tēnā.
Nō reira, ko tēnei homoni e kiia nei ko te aldosterone, ka hangaia e ngā repe tapatoru iti e rua, he rite ki te taupoki i runga i ō tātou whatukuhu. Ka kiia ēnei e tātou ko ngā repe adrenal. He wāhanga ēnei repe o tō tātou pūnaha endocrine.
Ko te mahi matua a tēnei homoni he pupuri i te toto toto kia tika . Mā te whakahaere i ngā taumata o ngā kohuke i roto i ō tātou toto e kiia nei ko te konutai (arā, te tote) me te pāhare pākawa. Ko ēnei momo konutai me te pāhare pākawa he momo electrolytes e rua. Ko ēnei ngā mea e pupuri ana i te taurite o ngā taumata wai o te tinana, ā, e āwhina ana hoki i ngā io me ngā uaua ki te mahi tika.
Whakaarohia te aldosterone hei kaiwhakahaere e whakahaere ana i te tote me te wai i roto i ō tātou tinana. Ki te tino teitei, ka puta he raruraru, ā, ki te tino iti, ka puta he raruraru.
Me pēhea te whakahaere a te aldosterone i te toto toto tiketike?
He tukanga tino whakamere tēnei. Ko te nuinga o te pānga o te Aldosterone ki te toto toto i ēnei huarahi e whai ake nei:
1. Te Pupuri Konutai: Ka tohu te Aldosterone ki ō tātou whatukuhu me te koroni kia "tāpiri atu i te konutai (tote) ki te toto, kia nui ake ai te pāhare pāporo e tukuna ana i roto i te mimi."
2. Te pupuri wai: Ina tāpirihia te konutai ki te toto, ka puritia hoki te wai i roto i te tinana. He rite ki te tote e kukumea ana e te wai.
3. Te pikinga o te rahinga toto: Ina pupuri wai tātou i roto i ō tātou tinana, ka piki ake te rahinga toto katoa. Pērā i te whakakī i tētahi paipa wai ki te wai ka piki ake tōna pēhanga, ina piki ake te rahinga toto, ka piki ake anō hoki te pēhanga toto.
Mā tēnei, ina heke te toto toto, ka uru mai te aldosterone ka āwhina ki te whakahoki i tōna taumata ki tōna taumata hauora. Ka āwhina hoki tēnei homoni ki te whakahaere i te pH (arā, te taurite waikawa-pūtake) me ngā taumata electrolyte o te toto.
Me pēhea te whakahaere i ēnei taumata aldosterone? - He tukanga whakamiharo!
Kāore te Aldosterone e mahi takitahi. He wāhanga ia o tētahi tīma e mahi tahi ana. Ka karangatia tēnei pūnaha ko te Pūnaha Renin-Angiotensin-Aldosterone (RAAS) . He rite ki tētahi reihi whakawhiti.
Whakaarohia pēnei.
- Hipanga tuatahi: Ka heke tō toto toto (BP). Ka rongohia tēnei e ō tātou whatukuhu. Kātahi ka tukuna e ngā whatukuhu he whākōkī e kīia nei ko te renin ki roto i te toto.
- Hipanga tuarua: Ka haere tēnei renin ka wawahi i tētahi pūmua e kiia nei ko te angiotensinogen, e hangaia ana e tō tātou ate, hei wāhanga e kiia nei ko te angiotensin I. Engari kei te moe tonu, arā, kāore i te nui tōna mana.
- Hipanga Tuatoru: I a tēnei angiotensin I e haere ana i roto i te toto, ka pakaruhia e te angiotensin-converting enzyme (ACE) mai i ō tātou pukahukahu, ka hangaia he homoni tino kaha e kiia nei ko te angiotensin II . Koinei te toa tūturu.
- Hipanga Tuawhā: E rua ngā mahi matua a tēnei angiotensin II.
1. Ka whakawhāitihia ngā oko toto iti (arterioles). Ka piki tonu te toto toto i tēnei.
2. Ka haere ki ngā repe adrenal ka mea atu, "Āwhina! Kia tere te whakaputa i te aldosterone!"
- Te taahiraa whakamutunga: Ka tae mai te aldosterone ka kī atu ki ngā whatukuhu kia pupuri i te tote (konutai) me te wai, kia puta ai te pāhare pāporo. Ka whakanuia e tēnei te nui o te toto, ā, ka whakahokia te toto ki te āhua noa.
Kia oti katoa tēnei tukanga, ā, kia hoki anō te toto toto ki te āhua noa, ka mutu aunoa tēnei pūnaha. He pūnaha whakahaere tino uaua tēnei, engari he tino whakamiharo.
Me pēhea te ine i ngā taumata aldosterone?
Mena kei te raru tō tākuta ki te whakahaere i tō toto toto, ki te mea rānei he huringa kei roto i ō taumata pāhare pāporo toto, tera pea ka whakapae ia kei te kitea he aldosterone. Ko te whakamātautau matua mō tēnei ko te whakamātautau ōwehenga aldosterone:renin .
Nā te mea e mahi tahi ana te aldosterone me te renin, mā te ine i ngā taumata o ngā mea e rua ka āwhina i te tautuhi i te wāhi tuturu o te raruraru. Ko te tikanga ka mahia tēnei mā te tango i te iti o te toto mai i te uaua i tō ringa.
Hei tāpiritanga, ka taea te ine motuhake i ngā taumata aldosterone i roto i te toto, i te mimi rānei i kohia mō ngā haora 24.
He aha te mea ka tupu mēnā ka piki ake ngā taumata o te aldosterone?
Ina teitei ake te taumata o te aldosterone i roto i te tinana i te mea noa, ka kiia tēnei he hyperaldosteronism . Ko te tino take o tēnei he āhuatanga e kiia nei ko te aldosteronism tuatahi .E kiia ana hoki ko te mate a Conn.
He maha ngā wā ka puta mai tēnei āhuatanga i tētahi pukupuku iti, ehara i te matepukupuku (pai) e tupu ana i roto i te repe adrenal. Mā tēnei pukupuku ka nui rawa te aldosterone e whakaputa te repe. Ka piki ake te konutai (tote) i roto i te toto, ka heke te pāhare pāporo, me te kore taurite o te electrolyte.
| Ngā Tohu o te Hyperaldosteronism | |
|---|---|
| Te toto toto tiketike (hypertension) | Te toto toto tiketike e uaua ana ki te whakahaere ahakoa te rongoā. |
| Ānini | Ngā mamae o te upoko i ngā wā katoa. |
| ngoikore o te uaua | Te ngoikore o te tinana, ina koa ka iti rawa ngā taumata o te pāhare pāporo. |
| Te matewai nui me te mimi pinepine | Te matewai e kore e memeha ahakoa te nui o te wai e inuhia ana me te hiahia hoki ki te mimi i ngā wā katoa. |
Mena kei a koe ēnei tohu, inā koa he uaua ki a koe te whakahaere i tō toto toto, me kōrero koe ki tō tākuta mō tēnei.
He aha te mea ka tupu mēnā ka heke te taumata o te aldosterone?
Waihoki, ina iti iho te taumata o te aldosterone i roto i te tinana i te mea noa, ka kiia e mātou ko te hypoaldosteronism . Koinei te wā ka iti rawa te hanga o te homoni aldosterone, ka ngoikore rānei tana mahi. Ka taea e tēnei te hua ake he iti te taumata konutai (tote) i roto i te toto, he nui ngā taumata pāhare pāporo, me te āhua e kiia nei ko te metabolic acidosis (te pikinga o te waikawa i roto i te toto) .
He aha ngā take mō tēnei?
- Te mate a Addison:He mate pūnaha ārai mate onge tēnei. Ko te tikanga ka tahuri te pūnaha parepare o te tinana ki a ia anō, ka pakaru ngā repe adrenal. Ka whakaitihia te hanga o ngā homoni aldosterone me te cortisol.
- Te Whēkau Adrenal Hyperplasia (CAH): He āhuatanga ira tēnei e kitea ana i te whānautanga. Ka puta te ngoikore o ētahi whākōkī e hiahiatia ana hei hanga homoni i roto i ngā repe adrenal.
- Ētahi atu āhuatanga hauora: Ka pā tēnei āhuatanga ki te hunga mate huka, ki te mate tākihi, me te hunga e tino pāngia ana e te mate.
- Ētahi rongoā: Ka taea hoki tēnei āhuatanga te puta mai i ngā rongoā whakamamae mamae (NSAID) , ngā rongoā whakaheke toto pēnei i te heparin, me ētahi rongoā mō te ngākau.
| Ngā Tohu o te Hypoaldosteronism | |
|---|---|
| Te toto toto iti (hypotension) | He iti tonu te toto toto, he ngoikore te ngākau. |
| ngoikore o te uaua | Tinana kore ora, e wiri ana ngā uaua. |
| Whakapairuaki | Te āhua e hiahia ana koe ki te ruaki. |
| Ngā tere o te manawa | Kei te rongo koe i te pā o tō ngākau. |
| Te pā o te manawa kāore i te tika (Arrhythmia) | Te pāorooro o te ngakau kāore i te ōrite. |
Mena kei a koe ēnei tohu, he mea tino nui kia whakaritea he wā ki te toro atu ki tō tākuta me te kōrero mō tēnei mea.
Karere Tangohia ki te Kāinga
- He homoni nui te Aldosterone hei whakahaere i te toto toto tiketike.
- Ko te mahi matua ko te whakahaere i te taumata tote (konutai) me te pāhare pāporo o te tinana.
- Ka pā mai ngā raruraru hauora ki te nui rawa (Hyperaldosteronism) me te heke rānei (Hypoaldosteronism) o tēnei homoni.
- Mena kei a koe ngā tohu pēnei i te toto toto tiketike e uaua ana ki te whakahaere, te ngoikore o te uaua, te matewai nui, te hemo rānei, kōrero ki te tākuta.
- Mā te whakamātautau toto, mimi rānei ka taea e koe te whakaatu ki a koe te nui o ō taumata aldosterone.
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