Me ako tātou mō te Angiotensin, e whakahaere ana i tō toto toto.

Kua pāngia koe e ngā raruraru o tō toto toto? Tērā pea kua whakahuatia e te tākuta tētahi kupu pēnei i te Angiotensin i a ia e kōrero ana mō tō toto toto. He aha rawa tēnei angiotensin? He aha tōna hiranga ki ō tātou tinana? Me kōrero noa tātou mō tēnei i tēnei rā.

He aha rawa te Angiotensin?

He kupu ngāwari, he homoni te angiotensin i roto i tō tātou tinana. He rite ngā homoni ki ngā karere e rere ana i roto i ō tātou tinana. Ka haere rātou i roto i te toto, ka tohutohu i ngā whekau, i ngā uaua, i ngā kiko me ngā mea hei mahi, me te wā hei mahi. Nō reira, ko tēnei homoni e kiia nei ko te angiotensin te kaiwhakahaere matua o tō tātou toto toto , ā, ka whakahaere i te nui o te wai me te tote (ina koa ko te konutai) i roto i tō tātou tinana. Mā te whakawhāiti, te whakawhāiti rānei i ngā oko toto, me te āwhina i te tinana ki te mimiti i te wai me te tote.

E whā ngā momo angiotensin. Ka karangatia ēnei mā te whakamahi i ngā tau Rōmana: Angiotensin I, II, III, IV. O ēnei , ko te Angiotensin II te homoni matua me te homoni tino kaha. He rite ki te kāpene o te tīma. Mēnā ka heke, ka piki rānei te nui o tēnei angiotensin i roto i tō tātou tinana, ka pā ki tō tātou hauora. Nō reira, he mea tino nui te taurite o tēnei.

I ētahi wā ka hoatu e ngā tākuta he angiotensin II hanga-ā-ringa, ka hoatu mā te uaua (IV) ki ngā pakeke, hei whakahoki i te toto ki te noho noa, inā koa i ngā take kino pēnei i te septic shock, ina kua tino heke te toto ki raro rawa.

He aha te pānga o te Angiotensin II ki te tinana?

He homoni tino kaha te Angiotensin II. Ka haere ki ngā wāhi maha o roto i ō tātou tinana, ā, he maha ngā mahi ka mahia. Engari ko ōna pānga matua ko te whakanui ake i te nui o te toto, te whakanui ake i te toto toto, me te whakanui ake i ngā taumata konutai (tote). Ka pēnei te āhua:

• Ka whakaohokia ō repe adrenal ki te tuku i tētahi atu homoni e kiia nei ko te aldosterone . Mā tēnei aldosterone ka pupuri te tinana i te konutai, engari ka tukuna te pāhare pāporo ki roto i te mimi.
• Ka whakanui ake i te toto toto mā te whakawhāiti i ngā pakitara o ngā uaua iti (arterioles). Whakaarohia he rite ki te pēhi i tētahi paipa wai, ā, ka tere ake te rere o te wai.
• Ka pā ki te hypothalamus i roto i tō roro, ka matewai koe. Kātahi ka inu wai koe.
• Ka kōrero anō hoki ki te hypothalamus, ka hiahia koe ki te tote.
• Ka āwhina te repe pituitary ki te tuku i te homoni antidiuretic (ADH), e mōhiotia ana ko te vasopressin . Mā tēnei ADH ka mimiti anō ngā whatukuhu i te wai ki roto i te tinana, ka nui ake te wai i roto i te tinana.

He kīanga māmā noa iho, he mea nui te angiotensin II ki te whakapiki i te toto toto me te nui o te tote me te wai i roto i te tinana.

Me pēhea te whakahaere i ēnei taumata angiotensin?

He pūnaha uaua rawa tēnei, he rite ki tētahi raupapa o ngā tikanga e hono tahi ana. Ko tōna ingoa ko te Pūnaha Renin-Angiotensin-Aldosterone (RAAS) . Koinei te pūnaha matua e āwhina ana ki te whakahaere i te toto toto.

Whakaarohia, koinei te tīmatanga:

1. Tuatahi, ina heke tō toto toto , ka tukuna e ō whatukuhu tētahi whākōkī e kīia nei ko te renin ki roto i tō toto. Ko ngā whākōkī he mea hei tere ake i ngā tauhohenga matū.

2. Ka pakaruhia e tēnei renin tētahi pūmua e kiia nei ko te angiotensinogen , e hangaia ana i roto i te ate. Kātahi ka tukuna tētahi wāhanga o taua pūmua, arā, ko te homoni e kiia nei ko te angiotensin I. Engari kāore tēnei angiotensin I e mahi ana, arā, kāore e taea e ia te whai pānga nui ki a ia anō.

3. Kātahi, i te mea e rere ana tēnei angiotensin I i roto i te toto, ka pakaruhia e tētahi atu whākōkī e kiia nei ko te angiotensin-converting enzyme (ACE) i roto i ngā pukahukahu me ngā whatukuhu. Ko te wā tēnā ka hangaia ai te angiotensin II hohe.

Inaianei ka tīmata te mahi a tēnei angiotensin II hou:

• Ka whakawhāitihia ngā pakitara o ngā uaua iti (arterioles) ā, ka piki ake te toto toto.
• Waihoki, ka whakahaua ngā repe adrenal kia tukuna te aldosterone, ā, ka whakahaua te repe pituitary kia tukuna te ADH (vasopressin).

Mā tēnei aldosterone me te ADH e akiaki ngā whatukuhu ki te pupuri i te konutai (tote) i roto i te tinana. Mā te aldosterone ka puta te pāhare pāporo i roto i te mimi. Ina piki ake ngā taumata konutai i roto i te toto, ka pupuri hoki te tinana i te wai. Ka piki ake te rahinga toto me te toto toto. Koinei te wā ka oti te pūnaha renin-angiotensin-aldosterone. E mārama ana koe ki tēnei huringa?

Ka taea hoki te whakahohe i te pūnaha RAAS e ētahi atu homoni, pērā i te corticosteroids, te estrogen, me ngā homoni tairoi . Mena he raruraru kei tētahi wāhanga o tēnei pūnaha, ka pā ki tō toto toto, ki te konutai, me te pāhare pākawa. Engari he maha atu anō ngā mea ka pā ki te toto toto, pērā i te cholesterol teitei, te ira tangata, me ētahi rongoā.

Ka aha mēnā ka heke ngā taumata angiotensin?

Mena he iti iho ngā taumata o te angiotensin II i te mea noa (e kiia ana ko te ngoikore o te angiotensin ), ka puta pea ēnei raruraru:

• Te toto toto iti (te toto toto iti) .
• Te nui haere o te pāhare pāporo (hyperkalemia) .
• Te hekenga o ngā taumata konutai (hyponatremia) .
• Te nui rawa o te wai e puta mai ana i roto i te mimi.

He aha ngā tohu o te toto toto iti?

Tērā pea ka pāngia koe e ēnei āhuatanga:

• Pōuriuri, māuiui, me te hemo pea.
• Te tirohanga pōuri.
• Whakapairuaki.
• Mahi uaua.

Ngā tohu o te nui o te pāhare pāporo (Hyperkalemia)

Mena ka piki ake ngā taumata pāhare pāporo i roto i te tinana, ka puta pea ēnei mea:

• Mamae puku me te korere.
• Mamae o te uma.
• Te tere, te koretake rānei o te manawa o te ngakau (arrhythmia).
• Te ngoikore o ngā uaua, te ngoikore rānei o ngā peka.
• Whakapairuaki me te ruaki.

Ngā tohu o te iti o te konutai (Hyponatremia)

Mena ka heke te taumata o te konutai i roto i te tinana, ka puta ngā tohu pēnei i:

• Te mamae o te uaua, te ngoikore rānei.
• Whakapairuaki me te ruaki.
• Te ngoikore, te kore o te kaha.
• Te mamae o te upoko me te pōhēhē.
• Ngā hopukanga mate haurangi.

Mena kei a koe ēnei tohu, he mea tino nui kia kōrero koe ki te tākuta.

Ka aha mēnā ka piki ake ngā taumata angiotensin?

Nā, me titiro tātou ki ngā mea ka puta ina teitei ake ngā taumata o te angiotensin II i te mea noa. Mēnā ka tupu tēnei, ka pupuri te tinana i te wai (wai) kāore e hiahiatia, ā, ka piki ake te toto toto (hypertension). He maha ngā wā ka kitea tēnei āhuatanga i roto i te hunga e pāngia ana e te ngoikore o te ngākau . E whakapono ana ngā kaipūtaiao ko te nui rawa o te angiotensin ka whai wāhi atu ki te whakanui ake i te ngākau.

Waimarie, ka taea e ngā tākuta te tohu rongoā hei rongoā i te hunga he nui ngā taumata angiotensin II. Ko ngā mea tino noa ko ngā aukati ACE (pēnei i te enalapril) me ngā aukati angiotensin receptor (ARB) (pēnei i te losartan) . Heoi, pērā i te nuinga o ngā rongoā, ka pāngia pea ēnei rongoā e ngā pānga taha. Ina koa, ka nui ake ngā taumata pāhare pāporo i roto i te tinana (hyperkalemia). He mea nui kia tangohia tō rongoā kia rite ki tā tō tākuta e tohutohu ana, me te tirotiro auau.

Hei whakamutunga, ngā mea hei maumahara

Nā, kua mārama koe ki te hiranga o tēnei homoni e kiia nei ko te angiotensin hei whakahaere i te toto toto. He rite ki te taurite ngawari, he raruraru te iti rawa, he raruraru te nui rawa.

He mea nui kia mau tonu tō toto toto ki te taumata hauora. Waihoki, ki te mea kei te raru koe ki te whakahaere i tō toto toto nā ngā panonitanga o ō taumata tote (konutai), he mea pai kia kōrero koe ki tō tākuta mō ō taumata angiotensin. Kātahi ka taea e rātou te whakahaere whakamātautau hei tirotiro mēnā he kore taurite o ngā homoni te take o ō tohu.

Kia maumahara, kaua rawa e mutu, e tīmata rānei i te rongoā me te kore e pātai ki te tākuta.Me mahi ngā mea katoa kia rite ki ngā tohutohu a te taote. Kātahi ka taea e koe te noho hauora.

Angiotensin , toto toto tiketike, homoni, renin, aldosterone, aukati ACE, toto toto tiketike, toto toto iti