Kua kōrerotia e tō tākuta he teitei ō taumata cholesterol? Mena koinā, kua tīmata pea koe ki te tango i te statin. Koinei te tikanga tuatahi o te maimoatanga. Engari i ētahi wā kāore e ranea taua rongoā anake. Kāore rānei ētahi tāngata e aro ki ngā pānga taha o te rongoā. Koia te take e kōrero ana ngā tākuta mō tētahi momo rongoā hou e 'whakarerekē ana i te kēmu'. Ko ēnei e kiia ana ko ngā PCSK9 Inhibitors. Me kōrero tātou mō ēnei i roto i ngā kupu māmā i tēnei rā.
He aha ēnei aukati PCSK9?
He momo rongoā hou ēnei ka taea te whakaiti i te cholesterol 'kino', te cholesterol LDL rānei, i roto i ō tātou toto. E rua ngā momo rongoā matua kua whakaaetia i te ao i tēnei wā. Ko te `alirocumab (Praluent)` me te `evolocumab (Repatha)`.
Kua whakaatuhia e ngā rangahau he tino whai hua ēnei rongoā, e kiia nei ko ngā aukati PCSK9. I ētahi wā, ka taea e rātou te ārai i ngā whakaeke ngakau me ngā whiu . Ka taea te tango i ēnei rongoā ko rātou anake, me te tango tahi rānei me tētahi rongoā statin kua tangohia e koe. Engari kotahi te mea hei maumahara, he nui ake te utu i ētahi atu rongoā cholesterol.
Āe, kia titiro tātou me pēhea te mahi a tēnei rongoā i roto i te tinana.
Hei mārama ki tēnei, me whakaaro tātou ki tētahi kōrero poto. Ko te ate te okana matua e whakahaere ana i te cholesterol i roto i tō tātou tinana.
Whakaarohia he iti noa ngā "kaiwhiwhi" (ngā kaiwhakawhiwhi) o ō tātou pūtau ate e hopu ana, e tango ana hoki i te cholesterol kāore e hiahiatia ana mai i te toto. Koinei ngā mea e pupuri ana i te ma o ō tātou uaua toto.
Engari, kei reira tētahi atu pūmua e kiia nei ko te PCSK9 e hangaia ana e ō tātou tinana. Ko tāna mahi he kimi me te whakangaro i aua "kaihoroi" pai. Kātahi, nā te mea kāore he tangata hei tango i te cholesterol, ka kohikohi ki roto i te toto ka waiho ki roto i ngā pakitara o ngā uaua.
Koinei te wāhi e puta mai ai te āwhina a tā mātou kaikōrero, te rongoā aukati PCSK9. Ko tā tēnei rongoā he hopu i taua pūmua PCSK9 kino, ka aukati i tana mahi. He rite ki te hopu i tētahi tamaiti whanoke ka whakanoho i a ia ki runga i tētahi tūru. Kātahi ka taea e ā mātou "kaihoroi" te mahi i tā rātou mahi me te kore he arai. Ko te mutunga? Ka tere te heke o te taumata o te cholesterol LDL i roto i te toto.
He aha te rerekētanga o ēnei i ngā 'statins'?
Ko ngā statin me ngā aukati PCSK9 he momo rongoā e rua e whakaheke ana i te cholesterol, engari e rua ngā huarahi mahi a rāua. Mā tēnei ripanga koe e āwhina ki te mārama ki tēnei.
| Rerekētanga | Statin | Ngā Ārai PCSK9 |
|---|---|---|
| Mahi | Ka ārai i te hanga o te cholesterol i roto i te ate. | Ka ārai i te whakangaromanga o ngā kaiwhakawhiwhi e tango ana i te cholesterol mai i te ate. |
| Me pēhea te tango | He pire e tangohia ana i ia rā. | He werohanga ka hoatu i ia 2, i ia 4 wiki rānei. |
| Whakamahinga | He maha ngā wā ka whakamahia ko ia anake, koinei te kōwhiringa tuatahi mō te whakahaere i te cholesterol. | Ka taea te whakamahi takitahi, te whakamahi tahi rānei me ngā statin. He kaha ake ngā hua. |
Nā wai rā e hiahia ana ki te tango i tēnei rongoā?
He pātai nui tēnei nā te mea kāore e hiahiatia ana tēnei rongoā e te hunga katoa he nui te cholesterol. Ka ngana tuatahi tō tākuta ki te whakahaere i tō cholesterol mā te whakamahi i ngā statin. Engari ka whakaarohia pea e tō tākuta he aukati PCSK9 i roto i ēnei take e whai ake nei:
- Ngā āhuatanga ira o te cholesterol teitei: Kei ētahi tāngata he āhuatanga ira e kiia nei ko te "Familial Hypercholesterolemia." He hapa kei roto i te huarahi e whakahaere ai te tinana i te cholesterol. Ahakoa te horopeta nui rawa o ngā statins, he tino uaua ki ēnei tāngata te whakaheke i te cholesterol LDL ki te taumata hauora.
- Mō te hunga e tino mōrearea ana ki te mate ngakau, ki te whiu rānei: Mena kei a koe te mate ngakau, ā, kāore i te tino whakahaeretia ō taumata cholesterol mā te whakamahi i ngā rongoā pēnei i te statins, ka whakaarohia pea tēnei rongoā e tō tākuta.
- Mō te hunga kāore e taea te aro ki ngā 'statins': Tata ki te 10%-20% o te hunga e tango ana i ngā statin ka pāngia e ngā pānga taha pērā i te mamae uaua e kore e taea te manawanui, te ngoikore, me te mamae tinana . Mō ērā tāngata, he kōwhiringa pai pea tēnei.
Āhea te tākuta e hoatu ai tēnei rongoā?
E kore rawa te tākuta e hoatu i tēnei rongoā i te wā kotahi. He tikanga anō kei roto mō tēnei.
1. Tuatahi, hurihia tō momo noho: Ka kī tuatahi te tākuta kia pai te whakakori tinana, kia kai hoki i ngā kai hauora he iti te hinu, te huka, me te paraoa .
2. Muri iho, he 'Statin': Ki te kore e ranea ngā huringa o te momo noho, ka tīmatahia he statin. Ki te kore e heke te cholesterol, ka piki haere te horopeta.
3. Hei huarahi whakamutunga: Mena kāore tō cholesterol e taea te whakahaere ahakoa te horopeta nui rawa o ngā statin, ki te kino rānei ngā pānga taha, ka whakaarohia pea e tō tākuta he aukati PCSK9. Ka taea te whakatau mā te whakahaere i tētahi whakamātautau, pērā i te kaute konupūmā coronary, hei aromatawai i tō mōrearea ki te mate ngakau.
Me pēhea te whakamahinga o tēnei rongoā, ā, he aha ngā pānga taha?
Ka tukuna hei werohanga kiri raro i te kiri i ia rua, i ia whā wiki rānei . Ka taea te werohanga ki te kiri o tō puku, o tō huha o runga, o tō ringa o runga rānei. Mā tō tākuta, mā tētahi nēhi rānei koe e ārahi ki te tuku tika. He māmā noa iho, ā, kāore he mamae.
Ina tae ki ngā pānga taha, he iti noa iho ngā mea e tino kitea ana.
- Mamae tuara
- Ngā tohu rite ki te makariri (korokoro mākūkū, whakaputa hūpē)
- Whero, marō, mamae iti rānei i te wāhi i werohia ai
He mea tino nui: He onge noa iho, ka puta he mate pāwera kino. Mena ka puta ohorere mai he whewhe nui, he pupuhi o te mata, o ngā ngutu rānei, he uaua rānei ki te manawa , he āhuatanga ohorere tēnei. Mena ka puta tēnei, me haere tonu koe ki te tari ohorere o te hōhipera tata (ETU) .
Hei whakamutunga, mō te utu o ēnei rongoā, kāore i rite ki ngā rongoā noa, ā, he tino utu nui . Nō reira, kāore pea tēnei maimoatanga e taea e te katoa te utu. He pai ake te kōrero mārire ki tō tākuta mō tēnei mea, me te matapaki mēnā e hiahiatia ana e koe, mēnā he tika mōu, me ō whiringa utu.
Karere Tangohia ki te Kāinga
- He momo rongoā hou, tino kaha ngā aukati PCSK9, e whakaheke ana i ngā taumata cholesterol LDL ("kino") teitei.
- Kāore ēnei e tukuna mai hei pire hei tango i ia rā, engari hei werohanga ka hoatu i ia 2, i ia 4 wiki rānei.
- Ko te tikanga, ka tūtohutia ēnei mō te hunga whai mate ira-kolesterol, te hunga he nui te mōrearea ki te mate ngakau, te hunga rānei kāore e taea te aro ki ngā rongoā statin.
- He tino utu nui tēnei rongoā, nō reira me whakatau koe mēnā he tika tēnei māu i muri i te kōrerorero āta ki tō tākuta.
- Kaua rawa e whakatau i ngā rongoā i runga i ngā kōrero pakiwaitara, i ngā mea rānei e kitea ana i runga i te ipurangi. Me whai tonu i ngā tohutohu a tō tākuta.
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