Mwina mukudziwa kuti Ankylosing Spondylitis (AS) ndi matenda opweteka kwambiri omwe amayambitsa kupweteka ndi kuuma kwa msana ndi mafupa. Mukamachiza izi, ndikofunikira kwambiri kuchita masewera olimbitsa thupi ndikugwiritsa ntchito mankhwala omwe dokotala wanu wakupatsani molondola. Komabe, nthawi zina mankhwala awa angayambitse zotsatirapo zazing'ono. Koma musawaope. Si aliyense amene amakumana ndi zotsatirazi, ndipo zomwe munthu aliyense amakumana nazo zimakhala zosiyana. Chofunika kwambiri ndikulankhula ndi dokotala wanu ndikusankha njira yothandizira yomwe imagwira ntchito bwino kwa inu komanso yomwe ili ndi zotsatirapo zochepa.
Mankhwala ochepetsa ululu oyamba: NSAIDs
Madokotala nthawi zambiri amalemba mankhwala amtunduwu poyamba pa AS. Timatcha mankhwala osapweteka a Nonsteroidal Anti-inflammatory, kapena NSAIDs mwachidule. Mankhwalawa amagwira ntchito yochepetsa kutupa ndi kupweteka m'malo olumikizirana mafupa. Mwina munamvapo mayina awa:
- Ibuprofen (Advil, Motrin)
- Naproxen (Naprosyn)
- Indomethacin (Indocin, Tivorbex)
- Celecoxib (Celebrex)
Komabe, mankhwala awa akamwedwa mopitirira muyeso kwa nthawi yayitali, ntchofu yoteteza m'mimba mwathu imatha kufooka, zomwe zingayambitse zotsatirapo zina.
| Zotsatirapo zomwe zingakhalepo za NSAIDs |
|---|
| kutentha pamtima |
| Kutupa kwa matumbo a m'mimba |
| Zilonda zam'mimba ndi kutuluka magazi |
| Ngati muli ndi matenda a mtima omwe munali nawo kale, chiopsezo chanu cha matenda a mtima kapena sitiroko chimawonjezeka. |
Chofunika kwambiri ndikugwiritsa ntchito mankhwalawa pa mlingo wokha komanso kwa nthawi yonse yomwe dokotala wanu wakupatsani. Ngati mukumva kupweteka m'mimba, uzani dokotala wanu nthawi yomweyo.
Njira yamakono yochizira matenda: Biologics (IL-17 Inhibitors)
Mankhwala awa ndi apamwamba pang'ono komanso apadera. Amagwira ntchito polimbana ndi mankhwala enaake m'thupi omwe amayambitsa kutupa ndikuletsa ntchito yake. Secukinumab (Cosentyx) ndi Ixekizumab (Taltz) ndi awiri mwa mitundu iyi ya mankhwala. Amatchedwa IL-17 inhibitors . Ngakhale kuti awa ndi mankhwala othandiza kwambiri, angayambitse zotsatira zina zoyipa.
| Zotsatirapo zomwe zingakhalepo chifukwa cha biologics | Mwachidule... |
|---|---|
| Matenda a Kutupa kwa Matumbo (IBD) | Mankhwalawa angayambitse IBD yatsopano kapena zizindikiro zake zimakula kwambiri kwa munthu amene ali nayo kale. |
| Matenda | Izi zitha kuchepetsa kugwira ntchito kwa chitetezo chamthupi pang'ono, zomwe zingawonjezere pang'ono chiopsezo chotenga matenda monga chimfine ndi fuluwenza. |
| Kuopsa kwa khansa | Ngakhale kuti kafukufuku wa nyama wasonyeza kuti pali chiopsezo cha khansa, sizikudziwika bwino kuti chiopsezochi chili bwanji mwa anthu. Musachite mantha ndi izi, koma lankhulani ndi dokotala wanu za izi. |
Mankhwala oletsa JAK omwe amatengedwa ngati mapiritsi
Iyi ndi mtundu wina wa mankhwala omwe amachepetsa kutupa. Tofacitinib (Xeljanz) ndi imodzi mwa mankhwala omwe amatengedwa ngati mapiritsi. Izi zitha kukhala ndi zotsatirapo zoyipa.
- Mutu
- Kutsegula m'mimba
- Kutopa
- Kugunda kwa mtima
- Kuopsa kwa kuwonongeka kwa chiwindi
Choncho, dokotala wanu nthawi zonse amafufuza thanzi lanu pamene mukumwa mankhwalawa.
Corticosteroids, yomwe imaperekedwa nthawi zina
Izi nthawi zambiri si mankhwala a nthawi yayitali a AS. Komabe, ngati ululu ndi kutupa m'malo enaake mwadzidzidzi zikuwonjezeka kwambiri (kuphulika) , corticosteroid ingaperekedwe ku malo amenewo okha.Dokotala angasankhe kukupatsirani jakisoni. Zotsatirapo izi zimachitika nthawi zambiri mukazigwiritsa ntchito kwa nthawi yayitali. Koma jakisoni wa kanthawi kochepa sungayambitse zonsezi. Koma ndi bwino kudziwa.
| Zotsatirapo zomwe zingakhalepo za corticosteroids (makamaka ngati munthu agwiritsa ntchito nthawi yayitali) | |
|---|---|
| Kudya kwambiri komanso kunenepa kwambiri | Kutupa mosavuta |
| Kusintha kwa maganizo | Kufooka kwa minofu |
| Maso osawoneka bwino | Kuchepa kwa mphamvu yolimbana ndi matenda |
| Kutupa kwa nkhope kapena ziphuphu | Kuthamanga kwa magazi |
| Matenda a shuga kapena kuipiraipira kwa matenda a shuga omwe alipo | Kusowa tulo |
Mankhwala ena (Sulfasalazine ndi Methotrexate)
Sulfasalazine
Ngati mankhwala oletsa kupweteka kwa mafupa (NSAIDs) sakuchepetsa ululu wa mafupa (makamaka m'mapewa, m'manja, ndi m'miyendo), dokotala wanu angakulembereni mankhwala otchedwa Sulfasalazine (Azulfidine). Izi zimakhala ndi zotsatirapo zoyipa zochepa kwambiri.
- Kupweteka kwa mafupa
- Malungo
- Mutu
- Kuwonjezeka kwa chidwi cha khungu ku dzuwa
- Kutupa pakhungu kapena kuyabwa
- Kusanza
Methotrexate
Mankhwalawa angatengedwe ngati piritsi kapena jakisoni. Dokotala angakulangizeni kuti mutenge vitamini ya folic acid mukamamwa mankhwalawa. Chifukwa chake ndi chakuti zotsatira zoyipa za Methotrexate zitha kuchepetsedwa kwambiri ndi folic acid.
- Kusanza ndi kusanza
- Zilonda pakamwa
- Mutu
- Kumva kutopa
Kodi mungachite chiyani ngati zotsatirapo izi zitachitika?
Ichi ndi gawo lofunika kwambiri. Ngati mukukumana ndi kusintha kulikonse m'thupi lanu, zizindikiro zatsopano, kapena kusasangalala chifukwa cha mankhwala omwe mukumwa a AS, chinthu choyamba komanso chabwino chomwe muyenera kuchita ndikudziwitsa dokotala wanu nthawi yomweyo.
Musasiye kumwa mankhwala anu kapena kusintha mlingo nokha. Kuchita zimenezi kungapangitse kuti zikhale zovuta kuwongolera vuto lanu.
Dokotala wanu adzakuthandizani. Akhoza:
- Mlingo wa mankhwala omwe mwapatsidwa udzachepetsedwa pang'ono .
- Mudzasinthidwa kukhala mankhwala ena .
- Pamodzi ndi mankhwala omwe alipo panopa, mankhwala ena adzaperekedwa kuti athetse mavuto omwe alipo .
Mfundo apa ndi yakuti inu ndi dokotala wanu mugwire ntchito limodzi ngati gulu kuti mupeze chithandizo chabwino kwambiri chomwe chingagwire ntchito m'thupi lanu, popanda zotsatirapo zoyipa kwambiri, komanso popanda chiopsezo chachikulu. Choncho musachite mantha ndi chilichonse, ndipo lankhulani ndi dokotala wanu za chilichonse momasuka.
Uthenga Wopita Nawo Kunyumba
- Si mankhwala onse a Ankylosing Spondylitis (AS) omwe amachititsa zotsatirapo zoyipa, ndipo si aliyense amene angakumane ndi zotsatirapo zoyipa.
- Kudziwa za zotsatirapo zake ndi njira imodzi yabwino kwambiri yothetsera vutoli.
- Ngati mukumva kusasangalala chifukwa cha mankhwala anu, musapange zisankho nokha, ndipo nthawi zonse lankhulani ndi dokotala wanu.
- Cholinga cha dokotala wanu ndikupeza chithandizo chomwe chimagwira ntchito bwino kwa inu komanso chomwe chili ndi zotsatirapo zochepa.
- Ndikofunikira kwambiri kupita kuzipatala nthawi yake komanso kukambirana ndi dokotala wanu za vuto lanu nthawi zonse.
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