Tangoganizirani galu akukulumphirani mwadzidzidzi pamene mukuyenda mumsewu. Kapena mantha omwe mumamva musanachite mayeso ofunikira... Mtima wanu umayamba kugunda mofulumira, thupi lanu limazizira komanso kutuluka thukuta, maso anu amakula. Kwa masekondi angapo, thupi lanu lonse limakonzekera ndewu yayikulu kapena kuthamanga. Ichi ndi chomwe timachitcha kuti ' ndewu-kapena-kuthawa '. Kumbuyo kwa zonsezi kuli ngwazi ziwiri m'thupi lathu. Iwo ndi Epinephrine (Epinephrine) ndi Norepinephrine (Norepinephrine). Tikambirana za awiriwa lero.
Ndani akunena Epinephrine ndi Norepinephrine?
Mwachidule, awiriwa ndi amithenga m'thupi lathu. Onse awiri amatha kuchita zinthu ziwiri.
1. Monga mahomoni: Homoni ndi mankhwala omwe amayenda m'magazi mwathu ndipo amauza ziwalo zosiyanasiyana kuti "zichite izi." Epinephrine ndi Norepinephrine zimapangidwa makamaka ndi tiziwalo tiwiri tating'onoting'ono tomwe tili pamwamba pa impso zathu (tizilombo ta adrenal).
2. Monga ma neurotransmitters : Awa ndi mankhwala omwe amatumiza mauthenga pakati pa matiliyoni ambiri a maselo amitsempha muubongo wathu ndi dongosolo lathu la mitsempha. Amathandiza kulamulira chilichonse kuyambira pamtima pathu mpaka pamalingaliro athu.
Zonsezi zili m'gulu la mankhwala otchedwa catecholamines . Mbali ina yaikulu ya gululi ndi dopamine . Mankhwala onse atatuwa amagwira ntchito limodzi kukonzekera thupi lanu mukamakhala ndi nkhawa. Koma dopamine imadziwika bwino chifukwa cha zotsatira zake pa zinthu monga chisangalalo, kukumbukira, ndi chidwi chathu.
Pamene kuchuluka kwa mahomoni kumeneku kukukwera panthawi yovuta, thupi lanu limayankha motere:
* Kumawonjezera kuyenda kwa magazi kupita ku ubongo ndi minofu.
* Muli tcheru kwambiri.
* Kumawonjezera kugunda kwa mtima.
* Kumawonjezera kuthamanga kwa magazi.
Nthawi zina, ngati muli ndi zizindikiro zosatha monga kuthamanga kwa magazi komwe kumakhala kovuta kulamulira, nkhawa pafupipafupi, nseru, komanso mutu waukulu , dokotala wanu angakuwuzeni kuti muyesedwe magazi ndi mkodzo kuti muwone kuchuluka kwa ma catecholamines awa. Kuchuluka kwa izi nthawi zonse kungakhale chizindikiro cha khansa yamtundu wosowa kwambiri m'matenda ozungulira impso.
Kodi awiriwa amagwira ntchito mosiyana bwanji?
Ngakhale kuti epinephrine ndi norepinephrine zimagwira ntchito limodzi, ntchito zawo zazikulu zimasiyana pang'ono. Tiyeni tiwone momwe zimagwirira ntchito.
| Ntchito ya Norepinephrine (Noradrenaline) | Ntchito ya Epinephrine (Adrenaline) |
|---|---|
| Nthawi zambiri imagwira ntchito ngati cholumikizira ubongo , zomwe zikutanthauza kuti imanyamula mauthenga ochokera ku ubongo kupita ku ziwalo zina za thupi. | Nthawi zambiri imagwira ntchito ngati mahomoni . Imatulutsidwa kuchokera ku adrenal glands panthawi ya kupsinjika. |
| Imagwira ntchito m'thupi nthawi zonse , osati nthawi yamavuto yokha. Ntchito zake zazikulu ndikulamulira kuthamanga kwa magazi, kuwongolera kugona ndi kudzuka (kumakuthandizani kudzuka m'mawa), komanso kutithandiza kukhala maso tsiku lonse. | Imagwira ntchito makamaka panthawi ya 'Nkhondo-kapena-Kuuluka' , kukonzekeretsa thupi ku ngozi. |
| Kuchepa kwa mitsempha yamagazi kumachita gawo lalikulu pakulamulira kuthamanga kwa magazi . Komabe, ngati kuchuluka kwa magazi kukupitirira kukwera, kuthamanga kwa magazi kungachitike. | Zimachepetsa kumva kupweteka pakagwa ngozi. Izi zimakupatsani mwayi wothamanga kapena kumenyana ngakhale mutavulala. Zimawonjezeranso mphamvu zanu kwakanthawi. |
| Kuchepa kwa zinthu kumalumikizidwa ndi mavuto amisala monga kuvutika maganizo ndi ADHD . Ngakhale kuti kuchuluka kwa zinthu mwadzidzidzi kungayambitse chisangalalo chachikulu, kungayambitsenso mantha . | Kupsinjika maganizo kosalekeza kungayambitse kusakhazikika, kusowa tulo, komanso ngakhale kuwonongeka kwa mtima . |
Kodi izi zimagwiritsidwa ntchito bwanji ngati mankhwala?
Popeza zonsezi zimatha kukhudza thupi mwachangu komanso mozama, madokotala amagwiritsanso ntchito ngati mankhwala.
Nthawi yoti mupereke Norepinephrine
Norepinephrine ndi mankhwala omwe amaperekedwa makamaka pazidzidzidzi kuti athetse kuthamanga kwa magazi komwe kumakhala koopsa (Kuthamanga kwa magazi (BP ) ndikofunika kuti kuwonjezere ndikusungabe. Milandu yotereyi ndi iyi:
- Kumangidwa kwa Mtima
- Kugwedezeka kwa Septic (kugwedezeka komwe kungawononge moyo komwe kumachitika chifukwa cha matenda oopsa)
- Pa nthawi ya opaleshoni ya msana (Spinal Anesth ESI a)
- Poyankha mankhwala ena
- Ngati madzi akusonkhana mozungulira mtima (pericardial tamponade)
Kuphatikiza apo, mankhwala a vuto la kuchepa kwa chidwi (ADHD) ndi mankhwala ena oletsa kupsinjika maganizo amagwira ntchito powonjezera kuchuluka kwa norepinephrine muubongo.
Nthawi Yoperekera Epinephrine (Adrenaline)
Epinephrine yopangidwa imagwiritsidwa ntchito ngati mankhwala m'mikhalidwe yofunika kwambiri.
- Panthawi yobwezeretsa mtima ndi mapapo (CPR)
- Sungani diso lanu litatambasuka panthawi ya opaleshoni ya maso.
- Kuwonjezeka kwa kuthamanga kwa magazi mu septic shock
- Tsegulani njira zopumira mpweya mu mphumu (monga inhaler)
Kufunika kwa Epinephrine pa Anaphylaxis
Chimodzi mwa zinthu zofunika kwambiri zomwe zimagwiritsidwa ntchito ndi epinephrine ndi chithandizo chadzidzidzi cha ziwengo zoopsa komanso zoopsa, zotchedwa anaphylaxis.
Tangoganizirani munthu wina mwadzidzidzi akuvutika kudya chinthu monga mtedza, nkhanu, kapena kulumidwa ndi mavu.
- Pakhosi pamakhala ngati pakanikira komanso kutupa
- Kukuvuta kupuma.
- Kutsokomola, kutsekula m'mimba.
- Zikumveka ngati maloto oipa.
Mu nthawi ngati izi, mankhwala opulumutsa moyo ndi epinephrine. Mankhwalawa nthawi zambiri amaperekedwa kudzera mu cholembera chodzipangira jekeseni (monga EpiPen). Anthu omwe ali ndi ziwengo zazikulu nthawi zambiri amauzidwa ndi madokotala awo kuti azikhala ndi cholembera ichi nthawi zonse. Nthawi zina, muyenera kuchibaya nthawi yomweyo zizindikiro zikayamba. Chingathe kuchepetsa zizindikiro zoopsa mwachangu, monga kupuma movutikira.
Chofunika Kwambiri: Ngakhale jakisoni wa epinephrine atagwiritsidwa ntchito ndipo zizindikiro zake zitatha, ndikofunikira kupita ku chipatala chapafupi cha Emergency Department (ETU) kapena kuyimbira foni 1990 Suwaseriya. Izi zili choncho chifukwa zizindikiro zimatha kubwereranso mankhwalawo akatha.
Nanga chimachitika ndi chiyani ngati izi sizikwanira m'thupi?
Nthawi zina matupi athu amatha kupanga mahomoni ochepa awa. Zifukwa zake zimakhala zovuta, ndipo dokotala yekha ndiye angadziwe.
Mavuto okhudzana ndi kuchepa kwa norepinephrine:
- Nkhawa ndi Kuvutika Maganizo
- ADHD
- Mutu
- Mavuto okumbukira ndi kugona
- Kuthamanga kwa magazi pang'ono (Hypotension)
- Shuga wochepa m'magazi (Hypoglycemia)
Mavuto okhudzana ndi kuchepa kwa epinephrine m'magazi:
- Nkhawa ndi Kuvutika Maganizo
- Mutu
- Mavuto ogona
- Shuga wochepa m'magazi (Hypoglycemia)
Ngati mukupitirizabe kukhala ndi zizindikiro ngati izi, chinthu chabwino kwambiri choti muchite ndikulankhula ndi dokotala wanu.
Uthenga Wopita Nawo Kunyumba
- Epinephrine (Adrenaline) ndi Norepinephrine ndi magulu awiri ofunikira kwambiri pa yankho la 'Nkhondo-kapena-Kuuluka' lomwe limakonzekeretsa thupi lanu ku ngozi.
- Norepinephrine ndi mankhwala a neurotransmitter omwe amagwira ntchito nthawi zonse, kulamulira zinthu monga kuthamanga kwa magazi, chidwi, ndi tulo.
- Epinephrine ndi hormone yomwe imayamba kugwira ntchito makamaka panthawi yamavuto adzidzidzi.
- Norepinephrine imagwiritsidwa ntchito ngati mankhwala okweza kuthamanga kwa magazi komwe kuli kochepa kwambiri kotero kuti kungaike moyo pachiswe.
- Epinephrine ndi mankhwala opulumutsa moyo a matenda oopsa a anaphylaxis (anaphylaxis).
- Ngati muli ndi mavuto monga nkhawa, mutu, kapena kusintha kwa kuthamanga kwa magazi, onetsetsani kuti mwaonana ndi dokotala wanu kuti akupatseni malangizo.
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