Kodi chithandizo cha khansa chimayambitsa kufooka? Tiyeni tiphunzire za G-CSF! (Granulocyte-Colony Stimulating Factor)

Pamene inu kapena munthu amene mumamudziwa akulandira chithandizo cha khansa , kutanthauza chemotherapy , monga tonse tikudziwira, madokotala nthawi zambiri amati, "Muyenera kusamala, chifukwa maselo omwe amalimbana ndi matenda amatha kuchepa." Chifukwa cha izi ndikuti maselo a khansa akawonongeka, maselo athanzi omwe ndi ofunikira m'thupi lathu amathanso kuwonongeka pang'ono. Chifukwa chake, pali mtundu wapadera wa mankhwala womwe umathandiza chitetezo cha thupi panthawiyi. Ndicho chimene tikukamba lero.

Mwachidule, kodi G-CSF ndi chiyani?

G-CSF ndi mankhwala omwe amathandiza thupi lathu kupanga ma neutrophils ambiri, mtundu wa maselo oyera a m'magazi omwe amathandiza thupi lathu kulimbana ndi matenda. Ma neutrophils awa ali ngati asilikali oteteza thupi lathu. Zinthu monga majeremusi , mavairasi, ndi mabakiteriya zikalowa m'thupi, maselowa amalimbana nawo ndipo amatiteteza ku matenda. Tikayang'ana tanthauzo la dzina lakuti G-CSF, tingamvetse bwino izi:

• Granulocyte: Ili ndi dzina lomwe limapatsidwa mtundu wa maselo oyera a m'magazi . Ma neutrophils nawonso ndi mtundu wa granulocyte. G-CSF imalimbikitsa kwambiri kupanga ma neutrophils awa.
• Choyambitsa Matenda a Colony: Izi zili ngati puloteni yomwe imauza maselo "chochita." G-CSF imatha kuuza selo loyambira lomwe lili mu fupa lathu kuti, "Udzakhala neutrophil tsopano." Imathanso kuuza neutrophil yomwe ilipo kuti "igawanike ndikuchulukana."

Mwachidule, G-CSF ndi mankhwala omwe amapita ku mafupa athu ndikutumiza uthenga woti, "Mwadzidzidzi! Tikufuna asilikali ambiri oteteza (neutrophils), apange mwachangu ndikutulutsa m'magazi."

Kodi G-CSF imagwiritsidwa ntchito pa matenda otani?

G-CSF imagwiritsidwa ntchito makamaka pochiza ndi kupewa matenda a neutropenia . Matenda a neutropenia ndi pamene chiwerengero cha ma neutrophils m'magazi chili chotsika kuposa chachibadwa. Izi zikachitika, mphamvu ya thupi yolimbana ndi matenda imachepa kwambiri. Pali zifukwa zingapo zazikulu zomwe dokotala wanu angakupatseni mankhwala awa.

Pa nthawi ya chithandizo cha khansa (Chemotherapy)

Mankhwala a chemotherapy akamapha maselo a khansa, amathanso kupha ma neutrophils athanzi. Ichi ndichifukwa chake neutropenia imachitika kwambiri pambuyo pa chemotherapy. Nthawi zina izi zitha kukhala zoopsa. G-CSF imachepetsa chiopsezochi polimbikitsa mafuta am'mafupa kuti apange ma neutrophils atsopano mwachangu.

Pa nthawi yoika maselo oyambira

Anthu omwe ali ndi khansa kapena matenda ena a magazi angafunike kuikidwa maselo oyambira. G-CSF imathandiza pa izi asanayambe komanso atamaliza.

• Musanaikidwe: Pamene G-CSF iperekedwa, maselo ambiri ochokera mum'mafupa amatulutsidwa m'magazi. Kenako madokotala amasonkhanitsa maselo athanzi amenewo.
• Pambuyo pa kuikidwa kwa maselo ena: Maselo osazolowereka m'thupi la wodwalayo akawonongeka, maselo athanzi omwe adasonkhanitsidwa kale amabwezeretsedwa m'thupi. G-CSF imathandiza maselo amenewo kukula bwino ndikukhala maselo abwinobwino a magazi .

Matenda ena a neutropenia

Anthu ena amabadwa ndi neutropenia yoopsa. Ena akhoza kukhala ndi vutoli popanda chifukwa chomveka. Pazochitikazi, G-CSF imagwiritsidwanso ntchito kuwonjezera kuchuluka kwa neutrophil.

Mitundu ya G-CSF ndi momwe imaperekedwera

Mankhwala a G-CSF amapezeka pamsika m'maina osiyanasiyana. Izi zimasiyana pang'ono malinga ndi nthawi yomwe amagwira ntchito komanso njira yopangira. G-CSF nthawi zambiri imaperekedwa ngati jakisoni wolowetsedwa pansi pa khungu. Nthawi zina imaperekedwa ngati jakisoni wolowetsedwa m'mitsempha. Ngati mungathe kudzipatsa jakisoni kunyumba, dokotala wanu kapena namwino adzakufotokozerani momwe mungachitire.

Kodi zotsatirapo zoyipa za G-CSF ndi ziti?

Monga mankhwala ena aliwonse, G-CSF ili ndi ubwino ndi zotsatirapo zake. Koma kumbukirani, dokotala akukupatsani mankhwala awa chifukwa ubwino wake ndi woposa zoopsa zake. Zotsatirapo zambiri zimatha mankhwala akasiya kugwiritsidwa ntchito.

Chifukwa chiyani G-CSF imayambitsa kupweteka kwa mafupa?

Izi ndi zotsatira zoyipa zomwe anthu ambiri amakumana nazo. Ngakhale kuti chifukwa chenicheni sichikudziwika, asayansi amaganiza kuti ndi chifukwa chakuti G-CSF imayambitsa mafuta a m'mafupa kuyamba kupanga maselo atsopano mwachangu kwambiri. Kupanikizika komwe kumachitika chifukwa cha kukula mofulumira kumeneku ndi komwe timamva ngati ululu. Ululuwu nthawi zambiri umatha kupirira. Mutha kulankhula ndi dokotala wanu za izi ndikupeza mankhwala oyenera ochepetsa ululu.

Kodi muyenera kupita kwa dokotala liti?

Ndikofunikira kwambiri kuuza dokotala wanu za zotsatirapo zilizonse zomwe mumakumana nazo mukumwa G-CSF. Makamaka, ngati mukukumana ndi zizindikiro zotsatirazi, muyenera kupeza upangiri wa dokotala nthawi yomweyo . Nthawi zina mungafunike kupita ku Dipatimenti Yothandiza Padzidzidzi (ETU) ya chipatala.

• Zizindikiro za matenda: malungo, kuzizira, kupweteka pakhosi, chifuwa.
• Zizindikiro za ziwengo:Kutupa pakhungu, kutupa, kupuma movutikira .
• Kupuma movutikira mwadzidzidzi.
• Kugunda kwa mtima mwachangu.
• Kutupa mwadzidzidzi kwa manja kapena mapazi.