Tiyeni tiphunzire za mapiritsi a Glasdegib (Daurismo) omwe amagwiritsidwa ntchito pochiza khansa

Kodi dokotala wanu wakupatsani Glasdegib (Daurismo) kwa inu kapena munthu wina m'banja mwanu chifukwa cha khansa yotchedwa Acute Myelogenous Leukemia? Ndi mankhwala amphamvu kwambiri okhala ndi dzina lovuta. Chifukwa chake, iyi ndi njira yosavuta komanso yochezeka yolankhulirana za mankhwalawa, momwe amagwiritsidwira ntchito, komanso zomwe tiyenera kusamala nazo kwambiri.

Kodi Glasdegib ndi mankhwala amtundu wanji?

Mwachidule, Glasdegib ndi mankhwala omwe amalimbana ndi maselo a khansa ndikuletsa kukula kwawo. Maselo a khansa m'thupi lathu amafunikira mapuloteni apadera kuti akule. Chomwe mankhwalawa amachita ndikuletsa kugwira ntchito kwa mapuloteni amenewo. Mwanjira imeneyi, pamene maselo a khansa sangathe kukula, timalandira thandizo lalikulu pakulamulira khansa.

Mankhwalawa amagwiritsidwa ntchito makamaka pochiza mtundu wa khansa ya m'magazi yotchedwa acute myelogenous leukemia. Nthawi zina, dokotala wanu angakupatseninso mankhwalawa pa matenda ena. Dokotala wanu adzakufotokozerani izi mwatsatanetsatane.

Zinthu zofunika kwambiri zomwe muyenera kuuza dokotala wanu musanamwe mankhwalawa

Popeza Glasdegib ndi mankhwala amphamvu kwambiri, ndikofunikira kwambiri kudziwitsa dokotala wanu za matenda ena aliwonse omwe muli nawo. Ngati muli ndi matenda aliwonse omwe ali pansipa, uzani dokotala wanu za matendawa musanayambe kumwa mankhwalawo.

• Ngati muli ndi matenda a mtima.
• Ngati kale munali ndi kugunda kwa mtima kosasinthasintha.
• Ngati muli ndi mbiri ya matenda aliwonse okhudzana ndi minofu.
• Ngati muli ndi matenda a impso.
• Ngati muli ndi matenda a chiwindi.
• Ngati kuchuluka kwa ma electrolyte m'magazi (monga potaziyamu, magnesium) kuli kotsika kwambiri kapena kokwera kwambiri.
• Ngati mwakhalapo ndi vuto la Glasdegib, mankhwala ena, zakudya, utoto, kapena zotetezera.
• Ngati muli ndi pakati, kapena mukukonzekera kutenga pakati posachedwa.
• Ngati ndinu mayi woyamwitsa.

Kodi mungagwiritse ntchito bwanji mankhwalawa moyenera?

Ndikofunikira kwambiri kumwa mankhwala monga momwe dokotala wanenera, mu mlingo woyenera, komanso panthawi yoyenera.

• Mezani piritsi lonse ndi kapu ya madzi. Musaliswe, kuliphwanya, kapena kulitafuna.
• Mungathe kumwa izi muli ndi chakudya kapena ayi. Koma chofunika kwambiri ndikumwa chimodzimodzi tsiku lililonse.Mwachitsanzo, ngati mwayamba kumwa mutadya, imwani tsiku lililonse mutadya. Ngati mwayamba kumwa musanadye, imwani tsiku lililonse musanadye.
• Musasiye kumwa mankhwala mwadzidzidzi popanda upangiri wa dokotala.
• Ngati mukupereka mankhwalawa kwa ana, lankhulani ndi dokotala wa ana za mankhwalawa ndipo mugwiritse ntchito motsatira malangizo ake.
• Ngati mwamwa mankhwala ochulukirapo mwangozi: Ngati mukuganiza kuti mwamwa mankhwala ochulukirapo, imbani nthawi yomweyo ku National Poison Information Centre ku Colombo National Hospital , kapena pitani ku Emergency Treatment Unit (ETU) yapafupi.

Kodi mumatani ngati mwaphonya mlingo?

Ngati mwaiwala kumwa mlingo, imwani mwamsanga mukangokumbukira. Komabe, ngati patatha maola osakwana 12 kuti mutenge mlingo wotsatira, dumphani mlingo womwe mwaphonya ndikumwa mlingo wotsatira panthawi yomwe mwakonza. Musamwe mlingo umodzi nthawi imodzi.

Kodi pali contraindications zogwiritsira ntchito mankhwalawa?

Glasdegib imatha kuyanjana ndi mankhwala ena, choncho ndikofunikira kuuza dokotala wanu za mankhwala onse omwe mukumwa.

Musamwe mankhwala awa ndi Glasdegib:

• Cisapride
• dronedarone
• fluconazole
• pimozide
• posaconazole
• saquinavir
• thioridazine

Mankhwalawa angagwirizanenso ndi Glasdegib:

• Mankhwala oletsa mavairasi a HIV kapena Edzi
• Mankhwala ena a matenda a bowa (monga itraconazole, ketoconazole)
• Maantibayotiki ena (monga clarithromycin)
• Mankhwala ena a khunyu (monga carbamazepine, phenytoin)
• Mankhwala ena omwe amayambitsa kugunda kwa mtima kosasinthasintha (amatalikitsa nthawi ya QT)
• Mankhwala achikhalidwe monga St. John's Wort
• Madzi a mphesa

Mndandanda uwu sunathe. Choncho perekani dokotala wanu mndandanda wathunthu wa mankhwala onse, mavitamini, mankhwala azitsamba, ndi zowonjezera zomwe mumamwa. Musaiwale kuwauza ngati mumasuta kapena kumwa mowa.

Zinthu zofunika kusamala kwambiri mukatenga Glasdegib

• Kuyezetsa magazi: Ndikofunikira kuti muyeze magazi (magazi) monga momwe dokotala wanu wanenera mukamamwa mankhwalawa.
• Mimba: Azimayi ayenera kupewa kutenga mimba akamamwa mankhwalawa komanso kwa masiku osachepera 30 atasiya kumwa mankhwalawa. Amuna ayeneranso kupewa kubereka mwana akamamwa mankhwalawa komanso kwa masiku osachepera 30 atasiya kumwa mankhwalawa. Mankhwalawa akhoza kuvulaza kwambiri mwana wosabadwa.
• Kuyamwitsa: Mukamamwa mankhwalawo komanso kwa masiku osachepera 30 mutasiya kumwa.Pewani kuyamwitsa mwana.
• Kupereka umuna ndi magazi: Pewani kupereka umuna kapena magazi mukumwa mankhwala ndipo kwa masiku osachepera 30 mutasiya kumwa.
• Kubereka: Mankhwalawa angakhudze kuthekera kwanu kubereka ana. Ngati muli ndi nkhawa iliyonse pankhaniyi, lankhulani ndi dokotala wanu.

Zotsatirapo zomwe zingachitike chifukwa cha mankhwala

Monga mankhwala ena aliwonse, Glasdegib ikhoza kukhala ndi zotsatirapo zake. Zina zimafuna chisamaliro chapadera, pomwe zina zimakhala zofala.

Ngati mukukumana ndi zizindikiro zina zachilendo zomwe sizinatchulidwe pamndandandawu, chonde dziwitsani dokotala wanu za zizindikirozo.