Dokotala akakuuzani kuti muli ndi khansa ya m'mawere , muyenera kuti munamva mantha ambiri komanso kudabwa. 'Ndichite chiyani tsopano?', 'Ndidzapatsidwa mankhwala amtundu wanji?', 'Kodi ndidzalandira mankhwala a chemotherapy ?' Mafunso ambiri ayenera kuti anabwera m'maganizo mwanu. Tikudziwa kuti kulimbana ndi khansa si ulendo wophweka. Koma sayansi ya zamankhwala ya masiku ano yapita patsogolo kwambiri. Panthawi ngati iyi, lero tikulankhula za mayeso apadera omwe amathandiza madokotala kusankha chithandizo chomwe angakupatseni.
Kodi Oncotype DX ndi chiyani?
Mwachidule, Oncotype DX ndi mayeso apadera omwe amayang'ana mozama maselo anu a khansa ya m'mawere . Si mayeso a magazi wamba. Amagwiritsa ntchito chidutswa cha minofu ya khansa yomwe yatengedwa kuchokera ku biopsy kuti atsimikizire khansa yanu kapena kuchokera ku opaleshoni kuti achotse chotupacho.
Mayesowa amayang'ana momwe majini ena amagwirira ntchito mkati mwa maselo a khansa. Monga momwe maselo athu onse amachitira, maselo a khansa alinso ndi majini. Majini amenewa ndi omwe amatsimikiza momwe khansa imakhalira, kutanthauza kuti ndi yoopsa bwanji, imafalikira mofulumira bwanji, komanso momwe ingabwererenso pambuyo pa chithandizo.
Mayeso a Oncotype DX amayang'ana kwambiri majini 21, ndichifukwa chake mungamve akutchedwa mayeso a "21-signature gene". Mwa kuwunika machitidwe a majini awa, madokotala amatha kuphunzira zambiri zofunika zokhudza khansa yanu.
Ndani akulangizidwa kuti achite mayeso awa?
Kuyeza kumeneku sikofunikira kwa wodwala aliyense wa khansa ya m'mawere. Dokotala wanu angakulangizeni mayesowa ngati muli ndi vuto lililonse mwa izi:
- Ngati muli ndi khansa yoyambirira (Gawo Loyamba kapena Lachiwiri): Izi zikutanthauza kuti khansayo sinafalikire kumadera akutali a thupi.
- Ngati khansa ili ndi estrogen-receptor positive (ER+): Izi zikutanthauza kuti maselo a khansa amakula chifukwa cha mahomoni otchedwa estrogen omwe amapangidwa ndi thupi lanu. Mtundu uwu wa khansa nthawi zambiri umachiritsidwa ndi mankhwala a mahomoni.
- Ngati khansayo sinafalikire ku ma lymph nodes omwe ali m'mwendo.
Kuphatikiza apo, mayesowa nthawi zina amatha kuchitidwa kwa anthu omwe ali ndi magawo oyambirira a khansa yotchedwa DCIS (Ductal Carcinoma in Situ) , kuti athandize kudziwa ngati chithandizo cha radiation chikufunika.
Chofunika kwambiri ndichakuti thandizo lalikulu kuchokera ku mayesowa ndi malangizo omwe mumapeza posankha ngati mukufunikira chithandizo cha chemotherapy kuwonjezera pa chithandizo cha mahomoni.
Kodi mumawerenga bwanji zigoli za mayeso?
Mayeso a Oncotype DX amakupatsirani "Recurrence Score" pakati pa 0 ndi 100. Ziwerengero izi zikakwera, chiopsezo choti khansa ibwererenso mukalandira chithandizo chimawonjezeka. Komabe, momwe ziwerengerozi zimawerengedwera zimasiyana pang'ono kutengera zaka zanu.
| Chiwerengero cha Zigoli | Chiwopsezo | Malangizo Otheka |
|---|---|---|
| 0 – 25 | Chiwopsezo chochepa | Chithandizo cha mahomoni chokha chingakhale chokwanira. Pali mwayi wochepa kwambiri woti chithandizo cha chemotherapy chikhale chothandiza kwambiri. |
| 26 - 100 | Chiwopsezo chachikulu | Chiwopsezo chakuti khansa ibwererenso n'chokwera. Mankhwala a chemotherapy komanso mankhwala a mahomoni angalimbikitsidwe. |
| Chiwerengero cha Zigoli | Chiwopsezo | Malangizo Otheka |
|---|---|---|
| 0 – 15 | Chiwopsezo chochepa | Chithandizo cha mahomoni chokha chingakhale chokwanira. Pali mwayi wochepa woti chithandizo cha chemotherapy chikhale chothandiza kwambiri. |
| 16 - 20 | Chiwopsezo chochepa chapakati | Chemotherapy ingapereke phindu laling'ono, koma muyenera kukambirana ndi dokotala wanu ngati phindu lake ndi lofunika poyerekeza ndi zotsatira zake. |
| 21 - 25 | Chiwopsezo chapakati | Ubwino wa mankhwala a chemotherapy ukhoza kukhala woposa zoopsa za zotsatira zake. Muyenera kukambirana izi ndi dokotala wanu ndikupanga chisankho. |
| 26 - 100 | Chiwopsezo chachikulu | Chiwopsezo cha khansa kubwerera n'chachikulu. Mankhwala a chemotherapy ndi omwe amalimbikitsidwa kwambiri pamodzi ndi mankhwala a mahomoni. |
Kodi chizindikiro ichi chokha ndi chomwe chimayambitsa chithandizo?
Ayi ndithu. Izi ndizofunikira kwambiri. Chiwerengero cha Oncotype DX ndi chimodzi mwa zinthu zofunika kwambiri zomwe zingakuthandizeni kupanga chisankho. Dokotala wanu adzaganizira zinthu zina zambiri asanapange njira yabwino kwambiri yothandizira.
Mwachitsanzo:
- Kukula kwa chotupa
- Kalasi ya chotupa
- Chiwerengero cha ma hormone receptors m'maselo a khansa
- Zaka zanu ndi thanzi lanu lonse
Zonsezi zimagwirizana kuti apange chisankho chomaliza. Chifukwa chake, lipoti la mayesoli ndi chida chimodzi chokha chomwe chingathandize dokotala wanu kupanga dongosolo labwino kwambiri la chithandizo kwa inu.
Kodi pali mayeso ena a majini ngati awa?
Inde, pali mayeso ena angapo a majini omwe amagwiritsidwa ntchito poyesa khansa ya m'mawere. Koma omwe amagwiritsidwa ntchito kwambiri ndi Oncotype DX. Tiyeni tiphunzire mwachidule za ena.
- MammaPrint: Izi zimayesa majini 70. Zimathandiza kuneneratu chiopsezo cha khansa kufalikira kunja kwa bere. Zingagwiritsidwe ntchito pa mitundu yonse ya ER+ ndi ER.
- Mammostrat: Izi zimayesa majini 5 ndipo zimayesa chiopsezo cha khansa ya m'mawere yomwe ili ndi mahomoni oyambira.
- Prosigna: Izi zimagwiritsidwa ntchito pa khansa ya m'mawere yokhala ndi mahomoni omwe amalandira mahomoni mwa akazi omwe asiya kusamba. Zimafufuza majini 58 ndikulosera chiopsezo cha khansa kubwerera kwina m'thupi mkati mwa zaka 10.
Zonsezi ndi mayeso apamwamba. Dokotala wanu adzasankha ngati mukufuna chimodzi mwa izi ndi chomwe chili choyenera kwambiri.
Uthenga Wopita Nawo Kunyumba
- Oncotype DX ndi mayeso apadera omwe amafufuza majini a maselo a khansa ya m'mawere kuti athandize kudziwa chiopsezo cha kubwereranso kwa khansa komanso ngati chemotherapy ikufunika.
- Izi zimachitika ndi chidutswa cha minofu ya khansa yotengedwa kuchokera ku biopsy kapena opaleshoni, osati kuchokera ku magazi.
- Kuyeza kumeneku sikofunikira kwa aliyense. Kumagwiritsidwa ntchito kwambiri pa khansa zomwe zili mu Gawo I/II, ER+, ndipo sizinafalikire ku ma lymph nodes.
- Zigoli zoyezetsa ndi gawo limodzi lokha la dongosolo la chithandizo. Dokotala wanu adzaganizira zinthu zina zambiri, monga kukula kwa khansa, kuopsa kwake, ndi zaka zanu.
- Ngati muli ndi mafunso kapena nkhawa zokhudzana ndi izi, onetsetsani kuti mwalankhula momasuka ndi dokotala wanu . Iye adzakuthandizani kusankha chomwe chili chabwino kwa inu.
Oncotype DX Sinhala, Khansa ya m'mawere, Chemotherapy, Kuyesa Majini a Khansa, Kubwerezabwereza kwa Khansa, Khansa Yabwino ya ER , Chithandizo cha Khansa
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