Kodi mumakumananso ndi zotsatirapo zoyipa mukamwa mankhwala a cholesterol (statins)? Tiyeni tidziwe tanthauzo lenileni la izi!

Amayi anu, abambo anu, kapena inuyo mwina mukumwa mankhwala a cholesterol, eti? Ma statin ndi mtundu wa mankhwala omwe madokotala amalangiza anthu ambiri mdziko lathu. Anthu ambiri omwe amagwiritsa ntchito mankhwalawa amatha kukhala ndi moyo wabwino popanda mavuto. Komabe, anthu ena amatha kukhala ndi zotsatirapo zazing'ono. Chifukwa chake lero, tikambirana za ubwino wa mankhwalawa komanso zotsatirapo zake.

Mwachidule, kodi statin ndi chiyani?

Ma statin ndi gulu la mankhwala omwe nthawi zambiri amaperekedwa ndi madokotala kuti athandize kuchepetsa kuchuluka kwa cholesterol m'magazi mwathu. Ntchito yayikulu ya mankhwalawa ndikuchepetsa kuchuluka kwa cholesterol m'magazi athu ndikutiteteza ku matenda oopsa monga matenda a mtima ndi sitiroko. Kafukufuku wasonyeza kuti kugwiritsa ntchito ma statins kungachepetse chiopsezo cha matenda a mtima, sitiroko, komanso imfa zomwe zimadza chifukwa cha matenda a mtima ndi pafupifupi 25%.

Tsopano, dokotala wanu adzayang'ana kuchuluka kwa cholesterol m'magazi mwa kuyeza magazi mosavuta. Ngati cholesterol yanu "yoipa", kapena LDL (Low-Density Lipoprotein) ili yokwera, muli pachiwopsezo chachikulu cha matenda a mtima. Dokotala wanu angakulembeni statin, makamaka ngati muli ndi zinthu zina zoopsa, monga matenda a shuga kapena kuthamanga kwa magazi.

Kodi mankhwalawa amagwira ntchito bwanji?

Mwachidule, mankhwala awa amaletsa ntchito ya enzyme yomwe imathandiza chiwindi chathu kupanga cholesterol. Pamene kuchuluka kwa cholesterol m'magazi mwathu kukukwera, kumayamba kusonkhana pa makoma a mitsempha yathu yamagazi. Zili ngati dzimbiri lomwe limasonkhana mkati mwa chitoliro chakale chamadzi. Pakapita nthawi, mitsempha yamagazi iyi imatsekeka, ndipo magazi amaundana amatha kutsekeka m'dera lomwe latsekeka, zomwe zingayambitse matenda a mtima kapena sitiroko. Ma statins amathandiza kuchepetsa cholesterol yoyipa (LDL) komanso kuwonjezera kuchuluka kwa cholesterol yabwino (HDL) , yomwe ndi yabwino kwa thupi lathu.

Kodi zotsatirapo zoyipa za ma statins ndi ziti?

Ngakhale anthu ambiri alibe mavuto, ena angakumane ndi zotsatirapo zina. Musadandaule, zambiri mwa izi sizowopsa.

Palinso machenjezo akuti ma statins angayambitse chiopsezo chochepa cha matenda monga kuiwalaiwala, kusokonezeka maganizo, kuchuluka kwa shuga m'magazi, ndi matenda a shuga a mtundu wachiwiri. Tikambirana zambiri za izi.

Zotsatira zoyipa zoopsa, koma zosachitika kawirikawiri

Ndikofunikira kudziwa zinthu izi, komanso muyenera kukumbukira kuti zinthuzi zimachitika kawirikawiri kwambiri .

• Myositis: Uku ndi kutupa kwa minofu, komwe kungayambitse kutupa. Chiwopsezochi chingawonjezeke pang'ono ngati ma statins atengedwa pamodzi ndi mankhwala ena.
• Rhabdomyolysis: Ichi ndi vuto lalikulu kwambiri, komanso losowa kwambiri.Zotsatirapo zake. Izi zimachitika pamene maselo a chiwindi amawonongeka kwambiri, ndipo mapuloteni omwe amatuluka m'magazi amasonkhana m'magazi ndikuwononga impso. Izi zingayambitse kulephera kwa impso. Koma musadandaule, vutoli ndi losowa kwambiri, ndipo limakhudza munthu m'modzi yekha pa anthu 10,000 omwe amatenga ma statin.

Mantha ndi nthano zofala zokhudza ma statins

1. Kodi mankhwala a statins amayambitsa kuiwala zinthu? Kodi amayambitsa matenda a dementia?

Kalelo panali mphekesera zoti mankhwala a statin angayambitse matenda a dementia. Koma kafukufuku wa zaka 20 zapitazi wasonyeza kuti izi ndi zabodza kotheratu. Ndipotu, kafukufuku wina akusonyeza kuti kumwa mankhwala a statin kungachepetse chiopsezo cha matenda a dementia mwa anthu ena.

2. Kodi pali kugwirizana pakati pa mankhwala a statin ndi matenda a shuga?

Izi ndi zovuta pang'ono. Anthu odwala matenda a shuga ali pachiwopsezo chachikulu cha matenda a mtima, kotero madokotala nthawi zambiri amawapatsa ma statins. Komabe, ma statins ali ndi chiopsezo chochepa chokweza shuga m'magazi. Izi zimachitika kwambiri kwa anthu omwe ali ndi matenda a shuga asanakwane. Popeza chiopsezochi ndi chochepa kwambiri, ubwino wa ma statins kwa anthu odwala matenda a shuga ndi waukulu kwambiri. Koma ndi bwino kukambirana ndi dokotala wanu za izi musanapange chisankho.

Zakudya ndi mankhwala ena omwe sagwirizana ndi mankhwalawa

Ma statins amatha kuyanjana ndi zakudya zina ndi mankhwala ena, zomwe zingawonjezere chiopsezo cha zotsatirapo zoyipa.

• Chipatso cha Mphesa: Ichi ndi chinthu chomwe anthu ambiri sachidziwa. Mankhwala omwe ali mu madzi a mphesa amatha kusintha momwe ma statin ena amagawikira m'thupi. Izi zingapangitse kuti mankhwalawo akhale ogwira mtima komanso kuyambitsa zotsatirapo zoyipa. Ngati mumakonda kudya kapena kumwa mphesa, lankhulani ndi dokotala wanu ngati zingakhudze mtundu wa statin yomwe mukumwa.
• Mankhwala ena: Ma statin amatha kuyanjana ndi mankhwala a matenda a mtima, mankhwala ena ochepetsa cholesterol, maantibayotiki ena, ndi mankhwala a HIV.

Kodi mungachite chiyani ngati zotsatirapo zake zichitika?

Ngati mukukumana ndi zotsatirapo zilizonse zoyipa, musasiye kumwa mankhwala mwadzidzidzi. M'malo mwake, lankhulani ndi dokotala wanu. Iye akhoza kukupatsani njira zothetsera mavuto monga:

• Siyani kumwa mankhwala kwa masiku angapo ndipo onani ngati zizindikirozi zayambadi chifukwa cha mankhwalawo.
• Sinthani mtundu wa statin yomwe mwapatsidwa.
• Chepetsani mlingo wa mankhwala.
• Taganizirani mtundu wina wa mankhwala ochepetsa mafuta m'thupi.

Anthu ena amamwa mankhwala otchedwa Coenzyme Q10 (CoQ10) pofuna kuchepetsa ululu wa minofu. Ngakhale ena amakhulupirira kuti izi zingathandize kuchepetsa ululu, sizinatsimikizidwe mwasayansi kuti zimagwira ntchito 100%. Ngati mukuganiza zogwiritsa ntchito chinthu chonga ichi, onetsetsani kuti mwalankhula ndi dokotala wanu za izi.