Kodi minofu yanu imatopa mosavuta? Tiyeni tikambirane za Myasthenia Gravis!

Kodi mumamva ngati nsagwada yanu yatha mwadzidzidzi ndipo mukuvutika kutafuna chakudya mukudya? Koma pakapita kanthawi, kusapeza bwino kumatha ndipo mutha kudyanso bwino? Ngati mwakumanapo ndi izi, ndiye kuti mutu womwe tikukambirana lero udzakhala wofunika kwambiri kwa inu. Uwu ndi matenda otchedwa Myasthenia Gravis .

Kodi Myasthenia Gravis ndi chiyani?

Mwachidule, myasthenia gravis ndi matenda osatha omwe minofu m'thupi lathu imatopa ndikufooka mwachangu. Chinthu chodziwika bwino pa izi ndichakuti minofu imafooka ikagwiritsidwa ntchito, kenako imalimbanso mukapuma. Zili ngati batire yomwe imafa mukamagwira ntchito, koma imatsitsimulanso mukaiikira pambali kwakanthawi.

Matendawa angakhudze magulu osiyanasiyana a minofu m'thupi. Tikatero, timatcha kuti `generalized myasthenia gravis`. Izi zingayambitse vuto la kutafuna chakudya, kumeza, kumwetulira, kukweza mapewa, kukweza mkono, kugwira chinthu mwamphamvu, kuimirira, ndi kukwera masitepe.

Ngakhale kuti matendawa angakhudze aliyense, amapezeka kwambiri mwa akazi azaka zapakati pa 20 ndi 40 komanso mwa amuna azaka zapakati pa 50 ndi 70. Ngati mayi amene ali ndi matendawa abala mwana, mapuloteni ena (ma antibodies) m'magazi a mayi amatha kupita kwa mwana, zomwe zimapangitsa kuti minofu ikhale yofooka kwakanthawi. Koma palibe chodetsa nkhawa, nthawi zambiri mkati mwa milungu ingapo thupi la mwana limachotsa zinthuzi ndipo minofu ya mwana imabwerera mwakale.

Kodi zizindikiro zofala za matendawa ndi ziti?

Kwa anthu ambiri, matendawa amayamba m'maso. Choncho zizindikiro zoyamba zingakhale kufooka kwa maso, kusawona bwino, kapena kuona kawiri. Pakatha chaka chimodzi kapena ziwiri, kufooka kumeneku kungafalikire ku minofu ina m'thupi.

Tiyeni tifotokoze zizindikiro izi mu tebulo ili m'munsimu.

Chifukwa chiyani izi zikuchitika? Chifukwa chake ndi chiyani?

Kuti timvetse izi, choyamba tiyenera kudziwa pang'ono za momwe mitsempha ndi minofu yathu imagwirira ntchito. Tangoganizani kuti mukafuna kukweza dzanja lanu, uthenga umachokera muubongo wanu motsatira mitsempha. Uthengawu umafika ku minofu pamalo olumikizirana pang'ono pakati pa mapeto a mitsempha ndi minofu. Mtumiki wa mankhwala omwe amanyamula uthengawu amatchedwa acetylcholine . Mankhwalawa, acetylcholine, akamangirira ku ma receptors mu minofu, minofu imachepa, ndiko kuti, imagwira ntchito.

Myasthenia gravis ndi matenda a autoimmune omwe amakhudza ziwalo zamkati.. Izi zikutanthauza kuti, chitetezo chamthupi chomwe chimateteza thupi lathu chimalakwitsa ndikuukira ziwalo zathanzi za thupi lathu. Chomwe chimachitika mu matendawa ndichakuti ma antibodies opangidwa ndi chitetezo chamthupi amatseka kapena kuwononga ma acetylcholine receptors omwe ndatchula kale. Kenako uthenga wochokera ku mitsempha sufika bwino ku minofu. Ichi ndichifukwa chake minofu imafooka.

Kodi dokotala amazindikira bwanji matendawa?

Ngati muli ndi zizindikiro izi, choyamba muyenera kuonana ndi dokotala. Iye adzakuyang'anirani za mitsempha yanu. Kenako, angakulangizeni mayeso angapo kuti adziwe vuto lanu.

• Kuyezetsa magazi: Kuyezetsa kumeneku kumachitika kuti muwone ngati magazi anu ali ndi ma antibodies enieni omwe amaukira ma acetylcholine receptors omwe ndatchulawa.
• Kuyesa phukusi la ayezi: Ngati chikope chanu chagwa, sungani phukusi la ayezi kwa mphindi ziwiri. Izi zimachitika kuti muwone ngati kuzizirako kumachepetsa kufooka kwa minofu kwakanthawi.
• Mayeso obwerezabwereza olimbikitsa mitsempha: Ma electrode amaikidwa pakhungu ndipo zizindikiro zazing'ono zamagetsi zimatumizidwa kuti ziyeze liwiro ndi kugwira ntchito bwino kwa mauthenga ochokera ku mitsempha kupita ku minofu.
• Mayeso a EMG (single-fiber electromyography): Electrode yopyapyala kwambiri yonga singano imalowetsedwa kudzera pakhungu kupita ku minofu ndipo ntchito yamagetsi pakati pa ubongo ndi minofu imayang'aniridwa.
• Kujambula zithunzi: Mungapemphedwe kuti mupange CT scan kapena MRI scan kuti muwone ngati muli ndi chotupa cha thymus (thymoma).
• Mayeso a ntchito ya m'mapapo: Mayesowa amachitika kuti adziwe ngati matendawa akhudza ntchito ya mapapo.

Mankhwala ndi zinthu zomwe mungachite kunyumba

Chithandizo cha matendawa chimadalira zaka zanu, kuopsa kwa zizindikiro zanu, komanso momwe matendawa afalikira mofulumira.

Mankhwala

Dokotala wanu angakulangizeni mankhwala monga:

• Mankhwala oletsa cholinesterase: Mankhwalawa amathandiza kulumikizana pakati pa mitsempha ndi minofu, zomwe zimathandiza kulimbitsa minofu.
• Corticosteroids: Izi zimalamulira ntchito ya chitetezo cha mthupi ndipo zimachepetsa kupanga ma antibodies oopsa.
• Mankhwala Oletsa Kutupa kwa Mthupi: Mankhwalawa amaperekedwanso kuti achepetse mphamvu ya chitetezo cha mthupi.

Mankhwala Apadera

Ngati zizindikiro zikuipiraipira mwadzidzidzi kapena opaleshoni isanachitike, dokotala wanu angakulangizeni chithandizo cha mtsempha (IV).

• Plasmapheresis: Izi zimaphatikizapo kutumiza magazi anu kudzera mu makina kuti asefe ma antibodies oopsa. Ngakhale kuti zotsatira zake zimakhala zachangu, zimatenga nthawi yochepa chabe.
• Mankhwala a Intravenous immunoglobulin (IVIg): Mankhwalawa akuphatikizapo kubaya ma antibodies abwino m'magazi mwanu. Izi zimasintha momwe chitetezo chanu cha mthupi chimagwirira ntchito komanso kuwongolera zizindikiro zanu.

Opaleshoni - Kuchotsa Thupi

Ngati matendawa ayambitsidwa ndi chotupa mu thymus gland, thymus gland imachotsedwa kwathunthu ndi opaleshoni. Ngakhale ngati palibe chotupa, zizindikiro za odwala ena zimakula thymus gland ikachotsedwa.

Kusintha kwa moyo

Kuwonjezera pa mankhwala, kusintha pang'ono moyo wanu kungathandizenso kuchepetsa zizindikiro.

• Sungani mphamvu mukamadya: Ngati mukuvutika kutafuna chakudya, idyani nthawi yomwe muli ndi mphamvu zambiri. M'malo mwa kudya chakudya chachikulu, idyani zakudya zazing'ono zingapo tsiku lonse. Sankhani zakudya zopanda thanzi.
• Gwiritsani ntchito zida zodzitetezera: Ikani zitsulo zonyamulira pafupi ndi chimbudzi ndi bedi, ndi zina zotero. Chotsani mphasa ndi zinthu zina pansi kuti muchepetse mwayi woti mugwere.
• Pezani thandizo kuchokera ku makina: Sungani mphamvu zanu pogwiritsa ntchito zipangizo zamagetsi (bulashi la mano lamagetsi, chotsegulira chitini) m'malo mwa ntchito zamanja.
• Gwiritsani ntchito chigamba cha maso: Izi zingathandize kuti munthu asamaone zinthu ziwiri. Mukamaonera TV kapena kuwerenga, tsekani diso limodzi ndipo mugwiritse ntchito maso onse awiri mosinthana.
• Konzani tsiku lanu: Gwiritsani ntchito mphamvu zanu mwanzeru. Pezani nthawi ya tsiku yomwe mumakhala ndi mphamvu zambiri ndipo chitani ntchito zapakhomo komanso zochita zakunja.