Chotupa chopanda tanthauzo m'thupi? Tiyeni tikambirane za (Undifferentiated Pleomorphic Sarcoma - UPS)!

Kodi mudamvapo chinthu ngati chotupa chomwe chikukula ndikukulirakulira kwinakwake m'thupi lanu? Nthawi zina, popanda chifukwa chomveka, mutha kutupa kapena dzanzi m'dzanja kapena mwendo. Ngakhale nthawi zambiri sitimayang'anira kwambiri zinthuzi, pakhoza kukhala china chake chachikulu chobisika kumbuyo kwawo. Lero, tikambirana za mtundu wapadera wa khansa womwe anthu ambiri samva kawirikawiri, koma ndikofunikira kwambiri kuti tonsefe tidziwe. Musachite mantha, tiyeni timvetse izi mosavuta.

Kodi ``Undifferentiated Pleomorphic Sarcoma - UPS'' ndi chiyani?

Mwachidule, ``Undifferentiated Pleomorphic Sarcoma'' kapena ``UPS'' monga momwe timaitchulira mwachidule, ndi mtundu wa khansa wotchedwa soft tissue sarcoma . Apa ndi pamene maselo a khansa amapangika m'minofu yofewa ya thupi lathu, monga minofu, minofu yamafuta, ndi mitsempha yamagazi.

Kawirikawiri, `(UPS)` iyi imayamba m'minofu yofewa ya manja kapena miyendo yanu . Nthawi zina imatha kuchitikanso m'mbali yakuya ya kumbuyo kwa mimba, yotchedwa `retroperitoneum` . Nthawi zambiri, `(UPS)` iyi imakhudza mafupa. Chomvetsa chisoni n'chakuti, nthawi zambiri iyi ndi khansa yamtundu woopsa kwambiri . Chifukwa chake imatha kufalikira ku ziwalo zina za thupi, makamaka mapapo kapena ma lymph nodes .

Kale, `(UPS)` iyi inkatchedwa `malignant fibrous histiocytoma` . Chifukwa chake n'chakuti ofufuza ankaganiza kuti khansa iyi imachokera ku maselo apadera a chitetezo chamthupi otchedwa `histiocytes` . Komabe, kafukufuku wamtsogolo adapeza kuti mwina imayambira m'maselo otchedwa `mesenchymal cells`, omwe amapanga minofu yolumikizana m'thupi lathu.

Tsopano tiyeni tione tanthauzo la mawu awiriwa m'dzina ili.

"Kusasinthika" kumatanthauza kuti maselo a khansa awa amawoneka osakhazikika komanso osakhazikika . Monga zoseweretsa zomwe zabalalika popanda dongosolo lililonse. Zakhala zosiyana kwambiri komanso zosakhwima kotero kuti n'zosatheka kudziwa bwino maselo athanzi omwe adayambira kapena ntchito yomwe adayenera kuchita.

Mawu akuti "pleomorphic" amatanthauza kuti maselo awa ndi osiyana mawonekedwe, kukula, kapena nucleus, malo olamulira a selo . Taganizirani ngati chipinda chomwe sichinapangidwe kuchokera ku nkhungu imodzi, chilichonse chimakhala chosiyana mawonekedwe ndi kukula. Maselo ena ndi ang'onoang'ono, ena ndi akuluakulu. Ena ndi ozungulira, ena ndi ataliatali. Ngakhale nucleus, yomwe ili ndi ma chromosome mkati mwa maselo, ndi yosiyana mu selo iliyonse. Ichi ndichifukwa chake maselo a khansa awa amakula mosiyanasiyana komanso mwachangu popanda kulamulira kulikonse.

UPS kwenikweni ndi mtundu wa khansa wosowa kwambiri . Mwachitsanzo, ku United States, matendawa amakhudza anthu osakwana 5,000 pachaka. Komabe, pakati pa mitundu ya ma sarcoma ofewa,Pamodzi ndi liposarcoma (khansa yomwe imayamba m'minofu yamafuta) ndi leiomyosarcoma (khansa yomwe imayamba m'minofu yosalala), (UPS) ndi mtundu wachitatu wofala kwambiri wa sarcoma ya minofu yofewa .

Kodi zizindikiro za `(UPS)` ndi ziti?

Zizindikiro za `Undifferentiated Pleomorphic Sarcoma (UPS)` zimatha kusiyana malinga ndi munthu. Anthu ena sangakumane ndi zizindikiro zilizonse. Komabe, pali zizindikiro zina zodziwika bwino:

• Chilonda kapena chilonda chomwe chikukula pang'onopang'ono: Ichi ndiye chizindikiro chachikulu. Chimamveka ngati chilonda kulikonse pathupi, makamaka m'dzanja, mwendo, kapena pamimba.
• Chotupa chopanda ululu chomwe chingasunthe kapena sichingasunthe chikakhudzidwa: Nthawi zambiri, chotupachi sichimayambitsa ululu kumayambiriro. Chifukwa chake, anthu ena sangachisamale kwambiri.
• Kumva dzanzi kapena kutentha chifukwa cha chotupa chomwe chikukankhira mitsempha: Nthawi zina, chotupachi chikakula, chimakankhira mitsempha yapafupi. Izi zingayambitse dzanzi m'manja kapena m'mapazi, kumva kunjenjemera, kapena kumva kutentha.
• Kutupa m'dzanja kapena mwendo: Ngati dzanja kapena mwendo watupa popanda chifukwa chomveka, zimenezo ziyeneranso kuganiziridwa.

Chofunika kwambiri, UPS nthawi zambiri siimasonyeza zizindikiro zoonekeratu. Nthawi zambiri sizimapweteka , ndipo pakhungu sipamasintha (monga kusintha kwa mtundu kapena zilonda). Komanso, zizindikiro zodziwika bwino monga kutentha thupi, kuchepa thupi, ndi kufooka sizimaonekera kawirikawiri.

Kodi zifukwa za `(UPS)` ndi ziti?

Akatswiri sakudziwabe chomwe chimayambitsa UPS. Chomwe akudziwa ndichakuti izi zimachitika chifukwa cha kusintha kwa DNA (molekyulu yomwe ili ndi chidziwitso cha majini athu) ya maselo athanzi. Komabe, chomwe chimayambitsa kusinthaku mu DNA sichinadziwikebe.

Zinthu Zoopsa Zomwe Zimawonjezera Chiwopsezo Chopanga UPS

Chinthu choopsa ndi chinthu chomwe chimawonjezera mwayi wopeza matenda. Pali zinthu zingapo zomwe zadziwika kuti zimayambitsa `(UPS)`. Koma kumbukirani, si aliyense amene ali ndi zinthuzi zomwe zingamuthandize kupeza `(UPS)`, ndipo sitinganene kuti anthu omwe alibe chilichonse mwa zinthuzi sadzadwala `(UPS)`.

Zinthu zomwe zadziwika kuti ndi zoopsa ndi izi:

• Kukhala mwamuna: Amuna ndi omwe ali pachiwopsezo chachikulu chotenga matendawa kuposa akazi, ndipo chiopsezo chachikulu chimakhala chachikulu pakati pa amuna oyera.
• Zaka zoposa 50: Kuchuluka kwa matendawa kumawonjezeka ndi ukalamba.
• Matenda ena: Mwachitsanzo, anthu omwe ali ndi matenda monga neurofibromatosis (vuto lomwe limayambitsa zotupa m'mitsempha) kapena matenda a Paget a mafupa (vuto lomwe limayambitsa kukula kosazolowereka kwa mafupa) ali pachiwopsezo chachikulu cha matenda (UPS).
• Matenda ena a majini:Anthu omwe ali ndi matenda osowa kwambiri a majini monga Li-Fraumeni syndrome ali pachiwopsezo chachikulu chotenga mitundu yosiyanasiyana ya khansa, kuphatikizapo (UPS).
• Kukumana ndi mankhwala enaake: Kukumana ndi mankhwala enaake kwa nthawi yayitali, monga arsenic kapena vinyl chloride, kungakhalenso chinthu choopsa.
• Chithandizo cha radiation chomwe chidachitika kale kudera lomwe lakhudzidwa: Ngati mudalandira chithandizo cha radiation kudera lina chifukwa cha matenda ena, pali chiopsezo chochepa chotenga sarcoma (UPS) m'dera limenelo pambuyo pake.
• Kukhudzidwa ndi kuwala kwa dzuwa kuntchito: Ngati muyenera kukhudzidwa ndi kuwala kwa dzuwa pantchito zina, zimenezo zingakhalenso zoopsa.

N'zodabwitsa kuti anthu ambiri omwe ali ndi UPS alibe chilichonse mwa zinthuzi zomwe zingawabweretsere mavuto . Choncho ngati muwona chinthu chomwe chikuwoneka ngati chotupa chachilendo pathupi lanu, musachinyalanyaze poganiza kuti, "Ine ndilibe chilichonse mwa zinthuzi zomwe zingawabweretsere mavuto."

Kodi madokotala amazindikira bwanji `(UPS)`?

Mukapita kwa dokotala yemwe ali ndi chotupa chonga ichi, choyamba adzakufunsani za thanzi lanu, ngati pali aliyense m'banja mwanu amene wakhala ndi matenda monga khansa (mbiri ya banja), ndi zina zotero. Kenako adzakufunsani za zizindikiro zanu. Kodi chotupachi chakhalapo kwa nthawi yayitali bwanji? Kodi chikukulirakulira? Kodi chikupweteka? Kuphatikiza apo, adzakuyesani zotsatirazi:

1. Kuyezetsa thupi: Dokotala adzafufuza komwe kuli chotupacho, kukula kwake, ndi momwe chimamvera chikakhudzidwa (cholimba kapena chofewa).

2. Mayeso ojambulira: Mayeso awa amathandiza kuona momwe chotupacho chikuonekera mkati ndi momwe chafalikira. Nthawi zambiri, mayeso amodzi kapena angapo, monga X-ray, ultrasound scans, ndi/kapena MRI scans, amatha kuchitika.

3. Kuyeza kwa thupi: Iyi ndi njira yofunika kwambiri yodziwira matendawa . Izi zimaphatikizapo kutenga minofu yaing'ono kuchokera ku chotupacho (mwina ndi chida chaching'ono chonga singano) ndikuchiyang'ana pansi pa maikulosikopu ndi katswiri wa matenda (dokotala yemwe ndi katswiri wodziwa matenda). Pamenepo ndi pomwe tinganene motsimikiza ngati ndi UPS kapena vuto lina.

Kodi mankhwala a `(UPS)` ndi ati?

Chithandizo cha UPS chimadalira zinthu monga kukula kwa chotupacho komanso ngati khansayo yafalikira. Chithandizo chachikulu cha UPS yoyambirira ndi opaleshoni yochotsa chotupacho . Izi nthawi zambiri zimachitika limodzi ndi chithandizo cha radiation . Komabe, nthawi zina chithandizo china cha khansa chingafunike.

Opaleshoni

Cholinga chachikulu cha opaleshoni ya UPS ndikuchotsa chotupa cha khansa kwathunthu.Madokotala amayesa kuchotsa osati khansa yokha, komanso minofu yathanzi yozungulira (izi zimatchedwa "malire") . Monga momwe timachotsera udzu m'munda, sitimachotsa chomera chokha, komanso dothi laling'ono lozungulira. Kenako palibe ngakhale chidutswa chaching'ono cha muzu wa udzu chomwe chimatsala. Mofananamo, madokotala akachotsa khansa iyi, amaichotsa pamodzi ndi minofu yathanzi yozungulira. Pokhapokha tingakhale otsimikiza kuti maselo onse a khansa achotsedwa popanda ena otsala. Ngati pali maselo a khansa m'mphepete mwa chotupa chochotsedwacho, zikutanthauza kuti pakhoza kukhala maselo ambiri a khansa otsala m'thupi.

Ngati chotupacho chili m'dzanja kapena mwendo wanu, dokotala wanu adzayesa kuchotsa khansayo ndikusunga ntchito yambiri momwe angathere m'dzanja kapena mwendowo. Komabe, nthawi zina, kudula chilonda kungakhale kofunikira . Chifukwa chake, ndikofunikira kulankhula ndi dokotala wanu wa khansa kuti asankhe njira yabwino kwambiri yothandizira matenda anu.

Mankhwala Owonjezera a Khansa

Madokotala a khansa angagwiritsenso ntchito njira zina zothandizira opaleshoni isanayambe kapena itatha. Ngakhale kuti njira zimenezi nthawi zambiri sizichepetsa chotupacho, zingathandize kuti opaleshoniyo ichotse chotupacho, kapena kupha maselo aliwonse a khansa omwe angakhalepo pambuyo pa opaleshoni.

Mankhwala ena owonjezera awa ndi awa:

• Chemotherapy: Kupereka mankhwala opha maselo a khansa.
• Chithandizo cha Immunotherapy: Kulimbikitsa chitetezo cha mthupi kuti chizilimbana ndi maselo a khansa.
• Chithandizo cha radiation: Kuwononga maselo a khansa pogwiritsa ntchito kuwala kwamphamvu kwambiri.

Ndondomeko yanu ya chithandizo ndi yapadera kwa inu. Ikhoza kukhala yosiyana ndi ya wina. Choncho lankhulani ndi katswiri wanu wa khansa za zomwe mungasankhe. Nthawi zambiri mudzalandira chithandizo ndi gulu la akatswiri osiyanasiyana . Gululi likhoza kuphatikizapo dokotala wa opaleshoni, katswiri wa khansa ya radiation, ndi katswiri wa khansa ya khansa. Ngakhale kuti katswiri aliyense ali ndi udindo wosiyana, onse amagwira ntchito limodzi kuti akuthandizeni. Adzakuthandizani kusankha chomwe chili chabwino pa vuto lanu.

Kodi ndiyenera kupita kwa dokotala liti?

Ngati muwona chotupa kapena chotupa chilichonse m'thupi lanu chomwe chikukula pang'onopang'ono , makamaka ngati chikugwirizana ndi zizindikiro monga kupweteka, kutupa, kapena kulephera kusuntha bwino mwendo wanu , muyenera kuwona dokotala nthawi yomweyo .

Ngati mwazindikira kale kuti muli ndi `(UPS)`, inuNgati muyamba zizindikiro zatsopano, kapena ngati zizindikiro zanu zikuipiraipira, uzani dokotala wanu wa khansa nthawi yomweyo .

Kodi munthu amene ali ndi `(UPS)` angayembekezere zinthu zotani?

Chiyembekezo cha moyo chimasiyana malinga ndi munthu. Zimatengera kukula kwa sarcoma ndi gawo la matendawa . Kawirikawiri, chiŵerengero cha moyo wa zaka zisanu cha anthu omwe ali ndi matenda apamwamba (UPS) ndi pafupifupi 60% . Izi zikutanthauza kuti pafupifupi 60% ya anthu omwe amapezeka ndi matendawa amakhalabe ndi moyo patatha zaka zisanu. Chiŵerengero cha moyo wa zaka 10 ndi pafupifupi 48% .

Koma kumbukirani, kuchuluka kwa anthu opulumuka kumeneku ndi kungoyerekeza chabe . Sikukuuzani nthawi yeniyeni yomwe mudzakhala ndi moyo kapena chithandizo chomwe chingakhale chothandiza kwambiri kwa inu. Kuti mudziwe zambiri za kuchuluka kwa anthu opulumuka komanso momwe zimakukhudzirani, ndi bwino kulankhula ndi gulu lanu la oncology.

Kodi `(UPS)` ingachiritsidwe kwathunthu?

(UPS) ndi yochiritsika kwathunthu, makamaka ngati yapezeka msanga . Ngakhale pamene matendawa afalikira, pali njira zina zothandizira zomwe zingathandize kukonza moyo wanu ndikutalikitsa moyo wanu. Monga momwe zilili ndi mtundu uliwonse wa khansa, kuzindikira ndi kuchiza msanga (UPS) ndiyo njira yabwino kwambiri yopezera zotsatira zabwino .

Zinthu zoti muganizire

Mukapezeka ndi khansa, ingakhudze mbali iliyonse ya moyo wanu. Ngati ndi khansa yosowa kwambiri monga Undifferentiated Pleomorphic Sarcoma (UPS), mungamve ngati muli nokha ndipo palibe amene akukumvetsani. Nthawi zina ngati izi, zingakhale zothandiza kulowa nawo gulu lothandizira komwe kuli ena omwe akukumana ndi zomwezo zomwe inu mukukumana nazo . Kulankhula nawo kungakuthandizeni kumvetsetsa momwe mukumvera ndikuthana nazo.

Komanso, gulu lanu lachipatala limakhalapo nthawi zonse kuti likuthandizeni . Akhoza kukulankhulani za njira zomwe mungasankhire chithandizo, kukuthandizani, ndikukupatsani chidziwitso ndi zinthu zomwe mukufunikira kuti mupange zisankho zolondola pa zaumoyo. Musaope kuwafunsa mafunso aliwonse omwe muli nawo . Kumbukirani nthawi zonse kuti simuli nokha.

` Undifferentiated Pleomorphic Sarcoma, UPS, sarcoma, khansa ya minofu yofewa, khansa, chotupa, zizindikiro za khansa, chithandizo cha khansa