Kodi minofu yanu imalimba ngati miyala? Tiyeni tikambirane za matenda osowa (Stiff Person Syndrome)

Tangoganizani kuti mwangokhala pansi ndipo mwadzidzidzi minofu yanu yamsana imakhala yolimba ngati mwala, yosatha kuyenda. Kapena kuti ngakhale phokoso laling'ono kapena wina akakumenyani zimapangitsa thupi lanu kugwedezeka ndipo minofu yanu ikugunda kwambiri. Izi sizingakhale kupweteka kwa msana kapena kupsinjika kwa minofu wamba. Lero tikulankhula za vuto losowa kwambiri lomwe anthu ambiri sanamvepo, koma ndikofunikira kwambiri kudziwa. Izi zimatchedwa Stiff Person Syndrome , kapena SPS mwachidule.

Mwachidule, kodi Stiff Person Syndrome (SPS) ndi chiyani?

Matenda a Stiff Person Syndrome ndi matenda osowa kwambiri okhudza mitsempha. Amakhudza ubongo wathu ndi msana. Mwachidule, ndi matenda a autoimmune . Izi zikutanthauza kuti chitetezo cha mthupi, chomwe chimayenera kuteteza thupi lathu ku matenda, chimayamba molakwika kuukira maselo athu athanzi. Matendawa ndi osowa kwambiri kotero kuti ngakhale m'dziko ngati United States, muli odwala osakwana 5,000 omwe amapezeka ndi matendawa.

Munthu amene ali ndi matendawa amayamba kumva kupsinjika m'minofu ya pakati pa thupi, kutanthauza kuti, m'dera la thunthu . Pakapita nthawi, kupsinjika kumeneku kumatha kufalikira m'manja ndi miyendo. Kuwonjezera pa kupsinjika kumeneku, minofu yopweteka kwambiri imathanso kuchitika. Chifukwa cha kupsinjika kumeneku, kaimidwe ka thupi kangasinthe pakapita nthawi, kuwerama pang'ono ndikuyang'ana mowerama .

Kugwedezeka kwa minofu kumeneku kungachitike mwadzidzidzi kapena kuyambitsidwa ndi china chake. Mwachitsanzo, phokoso lalikulu mwadzidzidzi, kugundana ndi winawake, kapena kupsinjika maganizo kwambiri kungayambitse kugwedezeka kumeneku.

Kodi zizindikiro zazikulu za matendawa ndi ziti?

Ngakhale zotsatira za matendawa zimasiyana pang'ono kuchokera kwa munthu ndi munthu, pali zizindikiro zina zomwe zimaonekera. Tiyeni tiwone patebulo.

N’chifukwa chiyani chinthu chonga ichi chimachitika?

Madokotala sanapezebe chifukwa chenicheni cha izi, koma mfundo yaikulu ndi yakuti ndi vuto la chitetezo chamthupi chathu.

Pali neurotransmitter yotchedwa GABA yomwe imathandiza kulamulira kayendedwe ka minofu yathu. Taganizirani izi ngati 'switch' yomwe imatumiza chizindikiro ku minofu yathu kuti 'ipumule'. Enzyme yotchedwa `glutamic acid decarboxylase (GAD)` ndi yofunika kwambiri popanga GABA iyi. Kwa odwala ambiri a SPS, thupi limapanga ma antibodies omwe amaukira enzyme iyi ya GAD. Ma antibodies amenewa akapita ndikuwononga enzyme ya GAD, GABA sipangidwa bwino. Kenako minofu silandira uthenga woti 'ipumule' bwino, ndipo nthawi zonse imakhala yolimba komanso yogwedezeka.

Anthu omwe ali ndi matenda a SPS ali ndi mwayi waukulu wokhala ndi matenda ena odziteteza okha.

• Vitiligo - mawanga oyera pakhungu
• Matenda a Shuga a Mtundu 1
• Kuchepa kwa magazi m'thupi (pernicious anemia) - Kuchepa kwa magazi m'thupi komwe kumachitika chifukwa cha kusowa kwa vitamini B12
• Matenda a chithokomiro ( thyroiditis )

Komanso, anthu omwe ali ndi mitundu ina ya khansa ali pachiwopsezo chotenga matenda a SPS (monga khansa ya m'mapapo, impso, bere, chithokomiro, khansa ya m'matumbo).

Kodi dokotala amazindikira bwanji matendawa molondola?

Zizindikiro za SPS nthawi zambiri zimawonekera pakati pa zaka 30 ndi 60. Akazi ali ndi mwayi wowirikiza kawiri wodwala matendawa kuposa amuna.

Popeza zizindikiro za matendawa zimafanana ndi za matenda ena ofala, SPS nthawi zambiri imasokonezedwa ndi matenda ena.

• Matenda a Multiple Sclerosis
• Matenda a Parkinson
• Fibromyalgia
• Kusokonekera kwa minofu
• Nkhawa

Chifukwa cha izi, zingatenge nthawi kuti mupeze matenda olondola. Dokotala wanu adzayamba wakuyang'anani, wakufunsani za mbiri yanu yachipatala, kenako walamula kuti muyesedwe kangapo kuti atsimikizire matenda ena.

1. Kuyesa magazi kwa ma antibodies a GAD: Iyi ndi njira yofunika kwambiri yoyezera. Ma antibodies a GAD amenewa amapezeka m'magazi a 60% - 80% ya odwala a SPS.

2. Electromyography (EMG): Izi zimayesa mphamvu yamagetsi ya minofu yanu ikamasuka komanso ikapanikizika. Minofu ya odwala SPS imakhalabe yogwira ntchito ngakhale ikamasuka.

Kodi mankhwala ochizira izi ndi otani?

Choyamba kunena ndi chakuti pakadali pano palibe mankhwala a matendawa . Komabe, pali njira zambiri zothandiza zomwe zingathandize kuchepetsa zizindikiro ndikukuthandizani kupitiriza ntchito zanu za tsiku ndi tsiku. Ndondomeko ya chithandizo imapangidwa kwa wodwala aliyense, kutengera zizindikiro zake.

Dokotala wanu adzayesa mankhwala osiyanasiyana kuti achepetse ululu ndi kupweteka kwa minofu. Si thupi la aliyense lomwe limayankha mankhwala mofanana, kotero zingatenge nthawi kuti mupeze mankhwala oyenera.

• Pakulimba kwa minofu: Benzodiazepines (monga diazepam, clonazepam) ndi baclofen nthawi zambiri amagwiritsidwa ntchito.
• Pa ululu: Mankhwala ochepetsa ululu ndi mankhwala ena oletsa khunyu angathandize kuchepetsa ululu.
• Chithandizo cha Intravenous Immunoglobulin (IVIG): Izi zimaphatikizapo kupereka ma antibodies ochokera kwa anthu athanzi kudzera m'mitsempha. Izi zawonetsedwanso kuti ndi mankhwala othandiza poletsa zizindikiro za SPS.

Kuwonjezera pa mankhwala, physiotherapy, masewero olimbitsa thupi, kutikita minofu, ndi acupunctureZinthu ngati izi zingathandize kuchepetsa ululu ndikupangitsa minofu kugwira ntchito.