Ese ufite ikibazo cyo kugabanuka k'uturemangingo tw'amaraso twera? Reka twige ku ndwara ya Autoimmune Neutropenia (AIN)!

Ese wigeze wibaza impamvu ubudahangarwa bwacu bw'umubiri, aho kuturinda, rimwe na rimwe bushobora gutangira kwibasira uturemangingo twacu? Iyo ni indwara igoye ariko yumvikana yitwa Autoimmune Neutropenia (AIN) . Icyo bibaho ni uko ubudahangarwa bwacu bw'umubiri bwibasira ubwoko bw'ingenzi cyane bw'uturemangingo tw'amaraso twera mu mubiri wacu, twitwa `neutrophils.` Reka tubiganireho mu buryo bworoshye, mu buryo ushobora gusobanukirwa.

None se, indwara ya Autoimmune Neutropenia (AIN) ni iki?

Mu magambo make, `Autoimmune Neutropenia` (AIN) ni indwara iterwa n'amaraso. Ikibaho hano ni uko ubudahangarwa bwacu bw'umubiri, bugomba kuturinda, bwibasira uturemangingo tw'amaraso twera twitwa `neutrophils`. Tekereza ibi, nk'ingabo zirinda igihugu cyacu zigatera abaturage bacu mu buryo butari bwo.

"Neutrophils" ni iki?

Neutrophils ni ingenzi cyane mu budahangarwa bwacu bw'umubiri. Ni nk'abasirikare bato mu mibiri yacu. Akazi kabo k'ingenzi ni ugushaka no gusenya ibintu byangiza byinjira mu mubiri, nka bagiteri n'ibihumyo bigira indwara. Rero, mu gihe cy'indwara ya `Autoimmune Neutropenia`, ubudahangarwa bwacu bwite bw'umubiri busenya utwo turemangingo tw'agaciro ka `neutrophils`, bityo umubare wa `neutrophils` mu maraso ugabanuka munsi y'urugero rusanzwe.

Hari ubwoko bubiri bw'ingenzi bwa AIN:

1. Neutropenia y'ibanze y'ubudahangarwa bw'umubiri (AIN): Ibi bikunze kugaragara mu mpinja n'abana bato . Ikigaragara hano ni uko umubare wa `neutrophils` ugabanuka nta yindi mpamvu. Ariko inkuru nziza ni uko ubusanzwe iyi ndwara ikemuka mu myaka mike.

2. Indwara ya Autoimmune Neutropenia ya kabiri (AIN): Ibi bikunze kugaragara cyane ku bana bakuru n'abantu bakuru . Aha, umubare muto wa neutrophil uterwa n'indi ndwara. Urugero, ishobora guterwa n'ubwandu, indi ndwara y'amaraso, cyangwa indi ndwara y'ubwiyongere bw'umubiri (indwara aho ubudahangarwa bw'umubiri bwibasira umubiri wabo). Iyi ndwara ya kabiri ya AIN akenshi iba idakira .

Umubare wa neutrophils witwa neutropenia ni muto gute?

Ubudahangarwa bw'umubiri (Autoimmune Neutropenia) ni ubwoko bumwe bw'indwara yagutse yitwa Neutropenia. Ubudahangarwa bw'umubiri bushyirwa mu byiciro byoroheje, biri hagati, cyangwa bikomeye, bitewe n'umubare wa neutrophils kuri mikorolitiro imwe (microL) y'amaraso.

• Neutropenia yoroheje: Neutrophils 1.000 - 1.500 kuri mikorolita imwe.
• Neutropenia iringaniye: Neutrophils 500 - 1.000 kuri mikorolita imwe.
• Neutropenia ikomeye: Neutrophils iri munsi ya 500 kuri mikorolita imwe.

Igikuru ni uko izi ndangagaciro zigomba kwemezwa na muganga. Niba ufite gushidikanya kuri ibi, ni ngombwa cyane gushaka inama kwa muganga.

Ni gute AIN igira ingaruka ku mubiri wanjye?

Uburyo AIN ikugiraho ingaruka bushobora gutandukana bitewe n'umuntu ku wundi. Biterwa n'ibintu byinshi, bityo ni byiza kuganiriza muganga wawe kuri ibi. Iyo umubare wa neutrophil yawe ugabanutse cyane, uba ufite amahirwe menshi yo kwandura . Hari igihe izi ndwara zishobora gushyira ubuzima mu kaga, cyane cyane iyo utabonye ubuvuzi bwihuse.

Ariko, mu bihe bimwe na bimwe, indwara yo mu bwoko bwa autoimmune neutropenia ishobora gutera gusa indwara zoroheje. Cyangwa ishobora kuba idatanga ibimenyetso. Niyo mpamvu ari ngombwa gukorana na muganga kugira ngo umenye icyateye indwara yo mu bwoko bwa neutropenia. Bitewe n'impamvu, muganga wawe ashobora gukurikirana uburwayi bwawe no kugufasha kugenzura ubwandu.

Ni nde urwara indwara ya Autoimmune Neutropenia (AIN)?

• AIN y'ibanze: Ibi byibasira cyane cyane impinja n'abana bato . Akenshi ipimwa mu gihe cy'amezi umunani.
• AIN ya kabiri: Ibi bikunze kubaho no ku yindi ndwara y’ubwiyongere bw’umubiri, nka lupus cyangwa rubagimpande. Abana bafite AIN ya kabiri bakunze kumenyekana bafite imyaka iri hagati ya 10. Abantu bakuru bafite AIN bakunze kumenyekana bafite hagati y’imyaka 40 na 60.

Ni mu rugero rungana iki indwara ya autoimmune neutropenia ikunze kugaragara?

Indwara ya AIN y'ibanze ni indwara idakunze kugaragara cyane . Ifata umwana umwe gusa mu bana 100.000 bari munsi y'imyaka 10. Bityo rero urabona ukuntu idakunze kugaragara.

Ni ibihe bimenyetso bya Autoimmune Neutropenia?

Indwara ya Autoimmune Neutropenia ntabwo itera ibimenyetso bikomeye buri gihe. Ariko, rimwe na rimwe ushobora kubona ibimenyetso by'ubwandu. Urugero:

• Indwara zo mu matwi: Iki ni kimwe mu bimenyetso bikunze kugaragara. Tekereza umwana wawe akomeje kubabara mu matwi, kandi iyo ugiye kwa muganga, bakakubwira ko ari indi ndwara yo mu matwi.
• Indwara zo mu myanya y'ubuhumekero: Kurwara ibicurane, inkorora n'umuriro kenshi.
• Indwara zo mu kanwa: Ibintu nk'ibisebe byo mu kanwa na gingivite.
• Indwara z'uruhu.
• Umusonga.
• Indwara ya meningite.
• Indwara zo mu nzira y'inkari (UTIs).
• Sepsis: Iyi ni indwara ikomeye cyane, ishobora gushyira ubuzima mu kaga.

Indwara zijyana na AIN y'ibanze akenshi ziba zoroheje, ariko indwara zikomeye nka pneumonia, meningitis, na sepsis zikunze kugaragara cyane muri AIN y'inyongera.

Ni iki gitera indwara yo mu bwonko bw’umubiri idakira?

AIN ishyirwa mu cyiciro cy’ibanze cyangwa icya kabiri bitewe n’impamvu y’urugero rwa neutrophil ruri hasi.

Neutropenia y'ibanze y'ubudahangarwa bw'umubiri (AIN y'ibanze)

Muri AIN y'ibanze, abasirikari b'umubiri bibasira kandi bigasenya neutrophils. Abasirikari b'umubiri ni ubwoko bwa poroteyine mu budahangarwa bw'umubiri wacu. Akazi kabo gasanzwe ni ugusenya ibintu byangiza, nka virusi na bagiteri, byinjira mu mubiri. Ariko kuri iyi ngingo, abashakashatsi ntibaramenya neza impamvu abasirikari bacu b'umubiri bigarurira izi neutrophils.

Neutropenia ya kabiri y’ubudahangarwa bw’umubiri (AIN ya kabiri)

Muri AIN ya kabiri, umubare wa neutrophils uragabanuka bitewe n'indi mpamvu cyangwa ikibazo. Ibi bituma ubudahangarwa bw'umubiri busenya neutrophils.

Ibintu bimwe na bimwe bishobora gutera ibi ni ibi:

• Izindi ndwara ziterwa n’ubwiyongere bw’umubiri: Urugero, harimo rubagimpande, lupus, na anemia y’umubiri iterwa n’ubwiyongere bw’amaraso.
• Kanseri: Urugero, `leukemia y'udukoko twinshi`.
• Indwara: Indwara nka `VIH`, `Parvovirus`, `umwijima B`.
• Ibibyimba: Kimwe na `Wilms tumor`, `Hodgkin's disease`.
• Indwara z'imitsi: Urugero, sclerosis nyinshi.
• Gutera impyiko cyangwa umwongo w'amagufwa.
• Imiti imwe n'imwe: Cyane cyane imiti imwe n'imwe ya chimiotherapie itangwa ku ndwara ya kanseri.

Ni gute indwara ya Autoimmune Neutropenia ipimwa? (Isuzuma)

Iyo ufite umuriro cyangwa indwara, muganga wawe ashobora gusanga umubare wa neutrophil uri hasi mu gihe cyo gukora isuzuma ry'amaraso kugira ngo amenye impamvu. Gusuzuma AIN bishobora kugorana gato, kuko hari impamvu nyinshi zishobora kuba zibitera. Muganga wawe ashobora gusuzuma AIN nyuma yo kwemeza izindi ndwara zishobora gutuma umubare wa neutrophil wawe uba muto.

Kugira ngo umenye cyangwa ukurikirane `Autoimmune Neutropenia`, muganga wawe ashobora gukora ibizamini bikurikira:

• Umubare wuzuye w'amaraso (CBC): CBC ishobora gusuzuma umubare wa neutrophils mu maraso yawe. Kubera ko izi ngero zishobora gutandukana, muganga wawe akunze gukora CBC zirenze imwe kugira ngo yemeze neutropenia kandi akurikirane urugero rwa neutrophils zawe. CBC zisanzwe nazo zishobora gufasha kumenya niba AIN yawe ari ndende.
• Gupima amaraso mu buryo bwo ku ruhande: Isuzuma ry'amaraso rikorwa hifashishijwe mikorosikopi kugira ngo harebwe imiterere n'imiterere y'uturemangingo tw'amaraso. Ibi kandi bifasha mu gusuzuma.
• Ibizamini bya Vitamine B12, folate, na umuringa: Ibi bizamini bishobora gusuzuma niba hari ibibura muri izi ntungamubiri. Umubiri urabikeneye kugira ngo ukore neutrophils.
• Ibipimo by'imikorere y'umwijima: Ibi bishobora kandi kugenzura imikorere y'umwijima no kumenya niba hari umwijima uterwa na virusi.
• VIH n'ubundi bushakashatsi ku biyobyabwenge: Kwandura virusi nka VIH na byo bishobora gutuma uturemangingo tw'umweru tw'amaraso tugabanuka.
• Isuzuma ry’imisemburo: Iki ni ikizamini cya laboratwari kireba ibimenyetso by’indwara ku turemangingo. Gikoreshwa mu kumenya niba neutropenia iterwa n’indwara y’ubwiyongere bw’umubiri.
• Gufata amashusho: Niba hari amakenga ko AIN iterwa na kanseri nka lymphoma, hashobora gukorwa MRI cyangwa CT scan.
• Gupima umwobo w'amagufwa no kuwupima: Aha, muganga afata urugero ruto rw'umusobo w'amagufwa akawusuzuma kugira ngo arebe ibimenyetso by'indwara. Ibi bishobora gufasha kumenya niba umwobo w'amagufwa uterwa na kanseri y'amaraso, nka kanseri y'amaraso.

Muganga wawe ashobora kandi gutegeka ko hakorwa isuzuma ry'amaraso kugira ngo arebe niba hari abasirikare b'umubiri mu maraso yawe bibasira neutrophils. Ibizamini bikunze kugaragara ni I-GIFT (Intaziguye granulocyte immunofluorescence test) na GAT (Granulocyte agglutination test).

Ikibabaje ni uko ibi bizamini bitahora byizewe mu gupima AIN. Bitewe n'impamvu yateye indwara ya neutropenia yawe n'igihe cyo gupima, ibi bizamini bishobora kudasuzuma abasirikari b'umubiri cyangwa bigatanga ibisubizo bitari byo. Ibisubizo bitari byo ni igihe ikizamini cyerekana ko abasirikari b'umubiri bahari mu gihe batari bahari.

Iyo umuganga akeka ko indwara yo mu bwonko iterwa n’indwara runaka, ashobora gusaba ko hakorwa ibindi bipimo.

Indwara ya Autoimmune Neutropenia ivurwa ite?

Uburyo bwo kuvura buterwa n'uburemere bw'indwara yawe. Urugero, umwana ufite indwara ya neutropenia idasobanutse ashobora gukenera gusa guhabwa CBCs zisanzwe n'umubare wa neutrophil, ariko ashobora kudakenera kuvurwa ako kanya. Niba umwana wawe afite indwara zandurira kenshi, muganga wawe ashobora kuguha imiti igabanya ubukana kugira ngo wirinde indwara zandurira. Imiti igabanya ubukana ikunze gutangwa kugira ngo ivure indwara zandurira, ariko iyi miti igabanya ubukana itangwa kugira ngo hirindwe ko indwara zandurira.

Ku muntu ufite AIN ya kabiri, muganga azavura indwara itera urugero ruke rwa neutrophil. Ashobora kandi kukwandikira:

• Granulocyte colony-stimulating factor (G-CSF): Ubu ni bwo buryo bw'ingenzi bwo kuvura indwara zikomeye za neutropenia. Bufasha umubiri gukora neutrophils nyinshi. G-CSF ishobora kandi gukumira indwara zikunze kugaragara zifitanye isano na AIN y'ibanze.
• Corticosteroids: Corticosteroids, nka prednisone, igabanya uburyo umubiri wawe witwara mu mikorere yawo, ikagabanya umubare w’uturemangingo twibasira utunyangingo tw’umubiri.
• Ubundi buryo bwo kuvura: Indi miti nka IVIG, rituximab, na alemtuzumab nayo yakoreshejwe ku barwayi barembye cyane bafite indwara ikomeye yo kwandura indwara z’ubwiyongere bw’umubiri.

Ese indwara ya Autoimmune Neutropenia ishobora kwirindwa?

Nta na kimwe muri AIN y'ibanze cyangwa AIN ya kabiri gishobora kwirindwa . Ariko, ushobora gukumira ingorane zijyana na `Autoimmune Neutropenia`, ni ukuvuga indwara zandura. Kugira ngo ubigereho, ugomba gufata ingamba zikenewe kugira ngo wirinde indwara zandura. Urugero, kwirinda ahantu hahurira abantu benshi, gukaraba intoki kenshi, no kwirinda abarwayi.

Ni ubuhe buryo bw'ejo hazaza umuntu urwaye indwara ya Autoimmune Neutropenia ashobora kwitega?

AIN y'ibanze ikunze kwiyahura ubwayo . Abana bagera kuri 95% bafite AIN urwego rwabo rwa neutrophil rusubira ku rugero rusanzwe bafite imyaka ibiri cyangwa itatu. Abana hafi ya bose bafite AIN y'ibanze bakira neza bafite imyaka 11. Ibi birahumuriza cyane, si byo se?

Mu bindi bihe, byitwa AIN ya kabiri, gukira kwawe biterwa n'ibintu byinshi, cyane cyane indwara yateye indwara yawe ya neutropenia. Kuvura iyo ndwara no gukumira indwara bishobora gufasha kongera umubare wa neutrophil yawe ku buryo busanzwe.

Ni ryari nkwiye gushaka inama kwa muganga?

Niba ufite indwara ikomeye yo kwandura indwara z’ubwiyongere bw’umubiri (autoimmune neutropenia) kandi ukagira umuriro, hita ubonana na muganga . Hari igihe muganga wawe ashobora kuba yarakwandikiye imiti igabanya ubukana mbere y’igihe kugira ngo uyifate niba ugize umuriro. Kenshi na kenshi, uzakenera kuvurirwa mu bitaro.

Niba ufite indwara ikomeye kandi ifata uturemangingo tw’umubiri igihe kirekire, muganga wawe azagusobanurira ibimenyetso ugomba kumenya n’icyo wakora kugira ngo wirinde ingorane.

Ibuka: Niba wowe cyangwa umwana wawe musanzwe murwaye AIN, ganira na muganga wawe uko ibagiraho ingaruka. Nubwo ibimenyetso n'impamvu bitandukanye, inkuru nziza ni uko uburyo bwo kuvura nka G-CSF bufite akamaro cyane mu kongera urugero rwa neutrophil.

Niba umwana wawe afite AIN, jya gupimwa amaraso buri gihe nk'uko muganga yabigutegetse. Witondere ibimenyetso by'ubwandu, kandi ushake ubuvuzi vuba bishoboka niba ubonye, ​​kugira ngo wirinde ingorane zishobora kubaho.

Incamake (Ubutumwa bwo kujyana mu rugo)

Sawa, rero ndizera ko ubu usobanukiwe neza indwara ya `Autoimmune Neutropenia` (AIN) twavuzeho.

• AIN ni indwara aho ubudahangarwa bw'umubiri bwacu bwangiza uturemangingo tw'amaraso twera twitwa `neutrophils`.
• Ibi bishobora kubaho ku bana bato (AIN y'ibanze) cyangwa ku bantu bakuru (AIN y'ibanze). AIN y'ibanze ku bana bato ikunze kwikemurira ubwayo.
• Ingaruka nyamukuru ni ukwandura indwara kenshi.
• Hariho ibizamini by'amaraso n'ibindi bipimo byo gusuzuma.
• Ubuvuzi burimo kwitabwaho, imiti igabanya ubwandu, G-CSF, na corticosteroids.
• Igikuru ni ukudatinya cyangwa guhangayika ahubwo ugashaka inama kwa muganga niba wowe cyangwa umwana wawe mufite ibi bimenyetso. Iyo bigaragaye hakiri kare kandi bigafatwa neza, ushobora kubaho ubuzima bwiza nubwo waba ufite AIN.

Niba ufite ibindi bibazo kuri ibi, menya neza ko wavugana na muganga wawe. Nibo bashobora kuguha inama nziza.

Neutropenia , Ubudahangarwa bw'umubiri, Uturemangingo tw'amaraso, Ubudahangarwa bw'umubiri, Indwara, Indwara z'amaraso, Indwara z'abana