Ibinini bya Mifepristone byo kurwanya indwara ya Cushing? Reka tubiganireho!

Ese ufite indwara ya Cushing ? Cyangwa hari umuntu uzi ufite iyi ndwara? Ikibaho muri iki kibazo ni uko umubiri wacu ukora imisemburo myinshi ya cortisol kuruta uko bikenewe, bigatuma urugero rw'isukari mu maraso, ni ukuvuga isukari, rwiyongera. Rero, imwe mu miti abaganga basaba mu bihe nk'ibi ni Mifepristone. Uyu munsi, turaganira ku binini bya Mifepristone mu buryo burambuye.

Ni ubuhe bwoko bw'umuti Mifepristone?

Mu magambo make, ibinini bya Mifepristone bikoreshwa cyane cyane mu kugenzura urugero rw'isukari mu maraso mu gihe cy'indwara ya Cushing's Syndrome , indwara ibaho iyo imisemburo ya cortisol mu mubiri wawe yiyongereye cyane.

Ese uzi ko iyi misemburo yitwa cortisol ari ingenzi ku mubiri wacu? Iyo dufite stress, umubiri wacu witegura guhangana nayo binyuze muri iyi misemburo. Urugero, iyo umubiri ukeneye ingufu nyinshi ako kanya, iyi cortisol ifasha kurekura isukari nyinshi mu maraso. Ariko, iyo ibi byiyongera mu buryo butunguranye, havuka ibibazo bitandukanye. Ibinini bya Mifepristone bigabanya ingaruka za hormone ya cortisol, bityo bikagabanya urugero rw'isukari mu maraso.

Uyu muti rimwe na rimwe ushobora kwandikirwa n'abaganga ku zindi ndwara. Kubwibyo, niba utazi neza icyo uyu muti ugenewe, ni byiza kubaza muganga wawe cyangwa umufarumasiye wo muri farumasi aho ugura umuti wawe. Uyu muti kandi uzwi ku isoko ku izina rya Korlym .

Ni ibihe bintu ngomba kubwira muganga mbere yo gufata uyu muti?

Mbere yo gutangira gukoresha ibinini bya Mifepristone, hari ibintu by'ingenzi ugomba kubwira muganga wawe. Kuko, abantu bafite indwara zimwe na zimwe cyangwa abafata indi miti bagomba kwitonda cyane mu gihe batanga Mifepristone. Reba niba ibi bikurikira bikureba:

• Ufite ikibazo cyo kuva amaraso ?
• Ese urwaye kanseri ubu cyangwa uri kuvurwa?
• Ese urwaye indwara yo mu mutwe nk'ihungabana ?
• Ese ufite ubundi bwoko bwa diyabete budafite aho buhuriye n'indwara ya Cushing?
• Indwara z'umutimaUrwaye indwara y'umutima?
• Ufite umuvuduko w'amaraso ukabije ?
• Ese ufite indwara y'umwijima?
• Ese abaganga bakubwiye ko urugero rwa potasiyumu mu maraso yawe ruri hasi?
• Ese wigeze uterwa urugingo rw'umubiri?
• Ese ubu urimo gufata imiti nka dexamethasone cyangwa prednisone?
• Ese uva amaraso mu gitsina udafite impamvu?
• Ese wigeze ugira ikibazo cyo kugira ubwivumbure kuri mifepristone, undi muti, ibiryo, irangi ry'ibiribwa, cyangwa imiti irinda ubushyuhe?
• Ese ubu urimo gushaka gutwita? Cyangwa wamaze gutwita?
• Ese uri umubyeyi wonsa? (Urimo konsa)

Niba ufite ikibazo nk'iki, ni byiza kukibwira muganga wawe nta kintu na kimwe uhishe .

Uyu muti nkwiye kuwukoresha nte?

Ibi binini bya Mifepristone bigomba gufatwa n'amazi. Ni ngombwa cyane gufata uyu muti icyarimwe buri munsi , nk'uko byavuzwe ku rupapuro rwa muganga. Ntukamene , ntukabishenye, ntukabihondagure cyangwa ngo ubihekenye. Mirira ikinini cyose n'amazi.

Ikindi kintu cy'ingenzi ni uko uyu muti ugomba gufatwa n'ibiryo. Nanone, ntugafate uyu muti hamwe n'umutobe w'imbuto z'umuzabibu ku mpamvu iyo ari yo yose. Ugomba gukomeza gukoresha uyu muti nk'uko byategetswe kugeza igihe muganga wawe azakubwiye kuwuhagarika.

Iyo uhawe uyu muti na farumasi, uzahabwa agapapuro karimo amabwiriza yihariye kuri uyu muti, kitwa MedGuide . Ni ngombwa cyane gusoma no gusobanukirwa aka gapapuro ka MedGuide witonze igihe cyose ufata umuti, ndetse n'igihe wongerewe.

Niba uha abana bato uyu muti, menya neza ko uganira na muganga wawe kuri wo, kuko ushobora gusaba ubugenzuzi n'ubwitonzi bwihariye bw'abaganga.

Wakora iki niba urenze urugero rw'imiti?

Niba ubona ko wafashe uyu muti urenze urugero, hamagara ikigo gishinzwe kurwanya uburozi kiri hafi yawe cyangwa icyumba cy’ubutabazi bw’ibanze cy’ibitaro bya leta kugira ngo bakugire inama.

Ibuka kandi: Uyu muti wanditswe kuri wewe gusa. Ntuwuhe inshuti cyangwa umuntu wo mu muryango wawe ku mpamvu iyo ari yo yose, kabone n'iyo yaba afite ibimenyetso nk'ibyawe.

Wakora iki niba wabuze dose y'umuti?

Niba wibagiwe gufata ikinini cya Mifepristone umunsi umwe, fata ako kanya wibuka. Ariko, niba igihe cyo gufata ikinini gikurikira kigeze, jya usimbuka ikinini cyabuze hanyuma ufate ikinini gikurikira ku gihe cyagenwe. Ntukigere ufata ikinini kabiri cyangwa cyiyongereyeho, ni ukuvuga gufata ikinini cyabuze n'icyo wagombaga gufata icyarimwe. Kubikora byongera ibyago byo kugira ingaruka mbi.

Ni iyihe miti yindi idakwiye gufatwa hamwe n'uyu muti?

Niba urimo gufata imiti ikurikira, ntukigere uyifata hamwe na Mifepristone. Iyi miti ishobora gutera ingaruka zikomeye kandi zishobora gushyira ubuzima mu kaga:

• Imiti imwe n'imwe ikoreshwa mu kuvura indwara z'ibihumyo, urugero, fluconazole, ketoconazole, na posaconazole.
• Hari imiti imwe n'imwe itangwa kugira ngo igabanye urugero rwa cholesterol mu maraso, urugero nka lovastatin na simvastatin.
• Cisapride
• Cyclosporine
• Dronedarone
• Alkaloids za Ergot ni ubwoko bw'imiti, urugero, dihydroergotamine na ergotamine.
• Fentanyl
• Pimozide
• Quinidine
• Sirolimus
• Tacrolimus
• Thioridazine

Uru rutonde ntabwo rukubiyemo ibintu byinshi, bityo ni ngombwa cyane kubwira muganga wawe imiti yose ufata, ndetse na vitamine.

Indi miti n'ibindi bintu bishobora kugira ingaruka ku buzima

Hariho indi miti n'ibintu bishobora kugira ingaruka kuri Mifepristone, bityo ni byiza kubimenya nabyo:

• Amwe mu moko ya antibiyotike, urugero nka clarithromycin, erythromycin, telithromycin.
• Hari imiti imwe n'imwe ivura indwara zandurira mu mitsi iterwa n'ubwandu bwa virusi itera SIDA cyangwa indwara z'umwijima nka hepatite.
• Imiti ikoreshwa mu kuvura indwara z'imitsi nko gucika intege, urugero nka carbamazepine, phenytoin, na phenobarbital.
• Imiti imwe n'imwe ibuza amaraso kuzura, urugero nka warfarin.
• Konivaptan
• Umutobe w'imbuto z'imizabibu - Nkuko byavuzwe mbere, iki ni ikintu kidakwiye gukoreshwa mu gihe ufata Mifepristone.
• Ibinini byo kuboneza urubyaro, inshinge, uduce duto n'ibikoresho birimo imisemburo.
• Itraconazole
• Imiti ivura indwara zo mu mutwe nko kwiheba cyangwa guhangayika cyane.
• Imiti imwe n'imwe igabanya ububabare itangwa nk'imiti igabanya ububabare.
• Indi miti ishobora gutera umutima kudakora neza, nk'indi yongera igihe cyo gukora QT.
• Repaglinide
• Rifabutin, Rifampin, Rifapentine.
• Umuti wa St. John ni inyongeramusaruro y'ibimera.
• Imiti ya steroid, nka prednisone cyangwa cortisone.
• Imisemburo ya tiroyide.
• Voriconazole.

Uru rutonde rushobora kuba rudakubiyemo ibintu byose. Kubwibyo, menya neza ko wabwiye muganga wawe imiti yose, ibyatsi, imiti idasaba muganga, n'inyongeramusaruro urimo gufata . Nanone, bwira muganga wawe niba unywa itabi, unywa inzoga, cyangwa ukoresha ibiyobyabwenge bitemewe n'amategeko. Ibi bishobora kugira ingaruka ku miti ya Mifepristone urimo gufata.

Ni ibihe bintu ugomba kwitondera mu gihe ufata uyu muti?

Mu gihe ufata Mifepristone, uzakenera kujya kwa muganga wawe kugira ngo agusuzume buri gihe kugira ngo akurikirane ubuzima bwawe. Muganga wawe ashobora kandi kukugira inama yo gukora isuzuma ry'amaraso.

Uyu muti ushobora kugira ingaruka ku rugero rw'isukari mu maraso. Niba urwaye diyabete, banza uganire na muganga wawe mbere yo guhindura indyo yawe cyangwa ingano y'imiti yawe ya diyabete.

Bika agapapuro k'amabwiriza yihariye y'uyu muti, kitwa MedGuide, witonze. Niba ukeneye ubuvuzi bwihutirwa, ereka itsinda ry'abaganga agapapuro ka MedGuide. Babwire kandi ko urimo gufata Mifepristone.

Ibintu byo kwitondera cyane ku bagore:

• Ugomba kwipimisha utwite kugira ngo wemeze niba utwite mbere yo gutangira uyu muti wa Mifepristone. Ntugatwite urimo gufata uyu muti cyangwa ukwezi kumwe nyuma yo guhagarika uyu muti.
• Niba uteganya gutwita cyangwa utekereza ko ushobora gutwita, bwira muganga wawe ako kanya. Uyu muti ushobora gutera ingaruka mbi zikomeye ku mwana uri mu nda. Baza muganga wawe amakuru arambuye.
• Ugomba gukoresha uburyo bwiza bwo kuboneza urubyaro mu gihe ufata Mifepristone. Uburyo bwo kuboneza urubyaro butari imisemburo ni bwiza mu gihe ufata uyu muti kandi mu gihe cy'ukwezi kumwe nyuma yo guhagarika uyu muti. Vugana na muganga wawe uburyo bwiza bwo kwirinda gutwita. Niba ukeka ko utwite, bwira muganga wawe ako kanya.

Ku babyeyi bonsa: Ntukonse umwana wawe mu gihe ufata uyu muti wa Mifepristone.

Ni izihe ngaruka mbi zishobora guterwa n'uyu muti?

Kimwe n'indi miti yose, Mifepristone ishobora gutera ingaruka zimwe na zimwe. Hari ingaruka zimwe na zimwe ugomba guhita ubibwira muganga wawe mu gihe zibaye. Izo ni:

• Indwara zo kugira ubwivumbure: Kuryarya uruhu, kuribwa, ibibyimba mu maso, ku minwa, ku rurimi cyangwa mu muhogo. Ibi bishobora guteza akaga.
• Imihindagurikire y'umutima: gutera kw'umutima vuba cyangwa gutera k'umutima ku buryo budasanzwe, isereri, kumva nta cyo ushoboye cyangwa ufite umutwe uhagaze neza, kubabara mu gatuza, guhumeka nabi.
• Ku bagore: Iminsi y'imihango idahwitse cyangwa kuva amaraso mu buryo budasanzwe (kugaragara kw'ibitotsi) mu gihe cy'imihango.
• Ibimenyetso by'imikorere mibi y'uturemangingo tw'intanga: isesemi, kuruka, kubura ubushake bwo kurya, intege nke cyangwa umunaniro udasanzwe, isereri.
• Ibimenyetso by'uko potasiyumu iri hasi mu maraso: kubabara imitsi cyangwa kuribwa mu nda, kumva ufite intege nke cyangwa umunaniro udasanzwe, umutima utera vuba cyangwa utari mwiza, kuribwa mu nda.

Ingaruka mbi zavuzwe hepfo akenshi si mbi cyane, ariko niba zikomeje cyangwa zikakubangamira, bwira muganga wawe:

• Kuzungera
• Umunaniro
• Umutwe
• Ububabare bw'ingingo
• Kubura ubushake bwo kurya
• Isesemi
• Kubyimba utubuto, amaboko, cyangwa ibirenge.

Uru rutonde ntirugaragaza ingaruka mbi zose zishobora guterwa na Mifepristone. Niba ubonye ibimenyetso bidasanzwe, bwira muganga wawe. Ushobora kandi gutanga raporo ku Kigo gishinzwe Ibiribwa n'Imiti muri Amerika (FDA) kuri 1-800-FDA-1088.

Ni gute nabika imiti yanjye?

Bika uyu muti wa Mifepristone ahantu hizewe kure y'abana bato n'amatungo . Ubike ku bushyuhe bw'icyumba, hagati ya dogere selisiyusi 20 na 25 (dogere selisiyusi 68 na 77). Reba itariki ntarengwa ku muti kandi ntuzigere ukoresha umuti warengeje igihe. Ujugunye neza.

Ni gute wajugunya imiti itagikenewe cyangwa yarangije igihe nta kwangiza ibidukikije?

• Amwe mu mafarumasi cyangwa ibitaro afite gahunda zo gufata imiti. Niba bishoboka, jyana imiti yawe muri imwe muri izi. Ushobora kumenya byinshi kuri ibi muri farumasi yawe cyangwa mu bugenzuzi bw'ubuzima rusange bwo mu gace utuyemo.
• Niba nta buryo bwo kuyisubiza, reba agapaki k'imiti cyangwa amabwiriza ari imbere kugira ngo urebe niba ikwiye kujugunywa mu myanda cyangwa igakurwa mu musarani. Niba utabizi neza, baza muganga wawe cyangwa umufarumasiye.
• Niba ushobora kubijugunya mu myanda, kuramo ibinini mu icupa cyangwa mu gapaki, ubyivange neza n'imyanda y'injangwe zakoreshejwe, ubutaka, ikawa yaseye, cyangwa ibindi bintu bisa nabyo bidakenewe. Hanyuma, shyira iyi mvange mu ishashi ya polythene cyangwa mu gikoresho cya pulasitiki gishobora kongera gufungwa, ugifunge neza, hanyuma ugijugunye mu myanda.

Amaherezo, ibintu byo kwibuka

Noneho rero, ubu urasobanukiwe ko Mifepristone ari umuti w'ingenzi ushobora gufasha mu kugenzura urugero rw'isukari mu maraso ku muntu nkawe ufite indwara ya Cushing Syndrome. Ariko kandi ubona ko hari ibintu byinshi ugomba kwitondera mu gihe uyikoresha.

By’umwihariko, ni ingenzi cyane kubwira muganga wawe neza ibyerekeye indi miti ufata n’izindi ndwara ufite, gufata imiti neza nk’uko muganga abivuga, mu gihe no mu rugero rwanditswe, kumenya ingaruka zishobora kubaho, no kwitondera cyane ibijyanye no gutwita no kuboneza urubyaro.

Niba ufite ikibazo cyangwa gushidikanya kuri uyu muti, ntugatinye kubaza muganga wawe cyangwa umufarumasiye wo muri farumasi kugira ngo abikemure. Wibuke ko ubuzima bwawe ari ingenzi cyane kuri wewe!

Mifepristone , indwara ya Cushing, cortisol, isukari yo mu maraso, adrenal gland, ingaruka mbi ku miti,