Ese umubiri wawe uhora uryarya? Ese uhinduka umutuku? Reka twige kuri iyi ndwara idasanzwe (Systemic Mastocytosis)

Ese rimwe na rimwe ujya uryarya umubiri wose? Ese isura yawe n'ijosi bihinduka umutuku mu buryo butunguranye ukumva urimo kugira ubushyuhe? Ese urwaye igifu, isereri, n'umutima utera umuvuduko mwinshi? Nubwo waba utekereza ko ibi bintu ari allergie gusa, rimwe na rimwe hashobora kubaho indi ndwara inyuma y'ibi, iyo tutarabyumva cyane. Uyu munsi turimo kuvuga ku ndwara imwe idakunze kugaragara, Systemic Mastocytosis. Ntugahangayike, reka tubisobanukirwe mu buryo bworoshye.

Mastocytosis y'umubiri ni iki?

Muri make, iyi ni indwara iterwa n’ubwiyongere budasanzwe bw’ubwoko bw’uturemangingo twitwa 'mast cells' mu mubiri wacu. Uturemangingo tw’amagufwa ni ubwoko bw’uturemangingo tw’amaraso twera. Tekereza utu turemangingo tw’amagufwa nk’abasirikare mu buvuzi bwacu bw’umubiri. Akazi kabo gakomeye ni ukuturinda indwara no kudufasha gukira iyo twakomeretse . Ariko muri iyi ndwara, utu turemangingo tw’amagufwa twiyongera cyane kandi mu buryo budasanzwe mu ngingo zitandukanye nko ku ruhu rwacu, mu musokoro w’amagufwa , mu magufwa no mu mara. Bigenda bite se? Bitewe n’impamvu runaka, utu turemangingo tw’amagufwa twinshi tuba dukora mu buryo butunguranye kandi tugasohora imiti myinshi nka 'histamine' mu mubiri. Ni bwo ibimenyetso navuze mbere, nko kunyara, kuribwa, no kurwara eczema , bigaragara.

Ni iki gitera iyi ndwara?

Abantu benshi bibaza niba iyi ari indwara ikomoka ku murage. Ariko iyi si indwara ikomoka ku murage. Akenshi, ibera muri gene yitwa KIT, iboneka mu turemangingo twacu twa mast.Biterwa n'impinduka mu buryo butunguranye (mutation). Iyi gene ifasha gukora poroteyine igenzura imikurire y'uturemangingo. Rero iyo ibi bihindutse, uturemangingo tw'amabere dutangira gukura mu buryo butunguranye. Nubwo ibi bimenyetso bishobora kugaragara mu myaka iyo ari yo yose, bikunze kugaragara ku bantu bakuze, cyane cyane hagati y'imyaka 40 na 50 .

Ibintu bitera ubwiyongere bw'ibimenyetso

Si abantu bose bafite iyi ndwara bahura n'ibimenyetso bimwe. Nanone, ibintu bitera ibimenyetso bishobora gutandukana bitewe n'umuntu ku wundi. Ariko, bimwe mu bintu bikunze gutera indwara biravugwa mu mbonerahamwe iri hepfo. Ni ngombwa kubimenya. Ni ngombwa kandi kwibuka ko rimwe na rimwe ibimenyetso bishobora kugaragara nta mpamvu runaka.

Ni ibihe bintu by'ingenzi n'ibimenyetso by'iyi ndwara?

Hari ubwoko butanu bw'ingenzi bwa Systemic Mastocytosis. Muganga wawe azagupima akakubwira ubwoko ufite.

• Indolent Systemic Mastocytosis (ISM): Iyi ni yo ndwara ikunze kugaragara cyane kandi idakabije cyane. Indwara igenda ikura buhoro buhoro kandi ntitera kwangirika gukomeye kw'ingingo.
• Indwara ya Smoldering Systemic Mastocytosis (SSM): Ikomeye gato kurusha ISM. Ibimenyetso birakomeye cyane kandi bishobora kugira ingaruka ku ngingo z'umubiri uko igihe kigenda gihita.
• Mastocytosis y’umubiri hamwe n’indwara y’amaraso ifitanye isano (SM-AHN): Muri iki gihe, mastocytosis iherekezwa n’indi ndwara ifitanye isano n’amaraso (urugero: leukemia ).
• Mastocytosis y’umubiri ikabije (ASM): Ubu bwoko butera imbere vuba kandi bushobora kwangiza ingingo nk'umwijima, urwagashya n'amagufwa.
• Leukemia y'ingirabuzima fatizo (MCL): Iyi ni yo ndwara idasanzwe kandi ikomeye cyane. Hari umubare munini w'uturemangingo tw'ingirabuzima fatizo mu musokoro w'amagufwa no mu maraso.

Ibimenyetso uhura nabyo biterwa n'ubwoko bw'indwara ufite n'aho mu mubiri wawe uturemangingo tudasanzwe tw’umusemburo tuba twinshi. Dore bimwe mu bimenyetso bikunze kugaragara:

• Kuryarya, gushyuha , guhumeka
• Kubabara mu gifu, kubyimba inda, impiswi
• Isesemi cyangwa kuruka
• Umutwe n'umunaniro
• Umutima wihuta cyane
• Umuvuduko w'amaraso uri hasi, isereri, guta ubwenge
• Kubyimba umwijima, urwagashya, n'uturemangingo tw'imitsi
• Indwara zo kubura amaraso n'indwara zo kuva amaraso
• Kugabanuka kw'amagufwa (Osteoporose)
• Mu mutwe, ibintu nko kugorwa no kwibanda ku bintu, guhangayika kenshi, cyangwa kwiheba.

Ni gute wasuzuma indwara? (Isuzuma)

Muganga wawe azabanza kukubaza ibimenyetso byawe hanyuma agukorere isuzuma ry’umubiri. Hanyuma, ashobora kukugira inama yo gupima byinshi kugira ngo yemeze ko ari indwara:

• Isuzuma ry'uruhu: Agace gato k'uruhu gafatwa mu gace kagize ikibazo kagasuzumwa hifashishijwe mikorosikopi kugira ngo harebwe niba hari uturemangingo twinshi twa mast.
• Isuzuma ry'amagufwa y'umusemburo w'amagufwa: Umuganga w'indwara z'amaraso akoresha urushinge ruto kugira ngo afate urugero ruto rw'umusemburo w'amagufwa yawe maze awusuzume.
• Ibipimo by'amaraso n'inkari:Isuzuma ry’amaraso yuzuye (CBC) rishobora kandi gukoreshwa mu gusuzuma izindi ndwara, nko kubura amaraso.
• Ikizamini cya Genetic: Ikizamini cy'amaraso cyangwa ingingo kirasuzumwa kugira ngo harebwe niba hari impinduka muri gene ya KIT twavuze haruguru.
• Ibizamini byo gupima: Imirasire ya X, ultrasound, na CT scans bishobora gufasha mu kumenya intege nke z'amagufwa no kubyimba kw'ingingo nk'umwijima n'umwobo.
• Endoskopiya cyangwa Colonoscopy: Umuyoboro muto ufite kamera iwufatanyeho ukoreshwa mu gusuzuma imbere mu gifu cyangwa amara kugira ngo harebwe niba hari ibisebe, nk'ibisebe.

Ni ubuhe buryo bwo kuvura?

Muganga azagena gahunda y'ubuvuzi akurikije ibimenyetso byawe, ingingo zangiritse, n'ubwoko bw'indwara.

• Antihistamines: Iyi miti ifasha mu kugenzura ibintu nko kuribwa k'uruhu, gutukura, no kubabara mu nda.
• Epinephrine: Imisemburo ikoreshwa mu gihe habayeho ubwivumbure bukomeye (anaphylaxis).
• Inhibitors za Pompo ya Proton: Kugenzura aside yo mu gifu no kugabanya ibintu nko kubyimba mu gifu.
• Imiti ihagarika irekurwa rya histamine mu turemangingo twa mast.
• Steroids: Ishobora gufasha ku ruhu n'ibimenyetso by'ubuhumekero.
• Uburyo bwo kuvura hifashishijwe ikoranabuhanga: Imiti igamije gene cyangwa poroteyine runaka igize iyi ndwara. Iyi miti ishobora gukenerwa ku bantu bafite ibimenyetso bikomeye.
• Ubwivumbure: Ubu buryo bwo kuvura bushobora kuba ngombwa mu gihe indwara ikwirakwira vuba kandi igatera kwangirika gukomeye kw'ingingo.
• Gutera uturemangingo tw’umugongo: Uburyo bwo kuvura bufatwa nk'ubusanzwe mu bihe bidasanzwe.

Mastocytosis y'umubiri, uturemangingo twa mast, uduheri tw'uruhu, anaphylaxis, anaphylaxis, gene ya KIT, histamine