Ese ni allergie gusa? Cyangwa ni indwara yo gukora uturemangingo twa Mast Cell Activation Syndrome (MCAS)?

Ese hari igihe utangira gushya, uruhu rwawe rugahinduka umutuku hanyuma ukarwara uduheri? Cyangwa ukumva urwaye mu nda ukumva ushaka kuruka? Hari igihe ibi bintu bibaho nyuma yo gukoresha imibavu runaka, cyangwa nyuma yo kurya ibiryo runaka, kandi rimwe na rimwe bishobora kubaho nta mpamvu na mba. Niba udashobora kubona impamvu ibitera, kandi ufite ibimenyetso bitandukanye mu bihe bitandukanye, birashoboka ko ari ikintu kirenze allergie gusa. Uyu munsi turimo kuvuga kuri imwe muri izo ndwara, Mast Cell Activation Syndrome (MCAS).

Indwara yo gukora abarwayi ba Mast Cell Activation Syndrome (MCAS) ni iki?

Muri make, MCAS ni indwara aho ubwoko bw'uturemangingo mu mubiri wacu twitwa 'mast cells' bigira ingaruka nyinshi kandi bitari ngombwa, bigatuma bisohora imiti myinshi irimo mu mubiri.

Noneho reka turebe icyo izi selile za mast ari cyo. Tekereza izi selile nk'abarinzi b'umubiri. Ni zimwe mu bigize ubudahangarwa bw'umubiri wacu. Akazi kazo k'ingenzi ni ukurwanya indwara zandura. Ariko kandi allergie iterwa n'izi selile. Akenshi, iyo ikintu cyatugizeho ingaruka mbi, urugero, ikintu kitwa allergie cyinjiye mu mubiri, izi selile za mast ziba zikora kandi zigasohora imiti yitwa 'abahuza'. Iyi miti ni yo itera allergie mu mubiri wacu. Ku muntu muzima, iyi nzira ni ukuturinda.

Ariko, ku muntu urwaye MCAS, izi selile za mast ziba zifite ubushobozi bwo kumva ibintu cyane . Zishishikazwa cyane n'ikintu gito cyane kandi zigasohora imiti myinshi icyarimwe. Ni nko kuzana ingabo zose gufata umujura muto. Iyi miti idakenewe ni yo itera ibimenyetso byinshi bidasanzwe kandi bibabaza twavugaga mbere.

Hari ibintu byinshi bishobora gutera izi selile za mast:

• Indwara zandurira mu mubiri
• Imiti imwe n'imwe
• Uburozi buturuka ku kurumwa n'udukoko
• Impumuro nziza
• Guhangayika
• Imyitozo ngororamubiri
• Ibiryo bimwe na bimwe
• Impinduka zitunguranye mu bushyuhe

Ese MCAS na Mastocytosis ni ibintu bitandukanye?

Yego, ntukivange ibi byombi. Nubwo byombi bifitanye isano n'uturemangingo twa mast, biratandukanye.

Ni izihe mpamvu zitera MCAS?

MCAS ishobora gushyirwa mu byiciro bitatu by'ingenzi hashingiwe ku mpamvu.

1. MCAS y'ibanze: Ibi biterwa n'ikibazo kiri mu turemangingo twa mast ubwatwo. Akenshi, impinduka muri gene ``(KIT)`` ituma utwo turemangingo twitwara nabi. Mastocytosis ni yo ndwara nyamukuru muri ubwo bwoko.

2. MCAS ya kabiri: Ibi bibaho iyo uturemangingo tw’imbere tw’umubiri dutewe n’indi mpamvu yo hanze. Urugero, ibi bishobora guterwa n’ingaruka zikomeye z’ubwivumbure, indwara idakira, cyangwa indi ndwara.

3. Idiopathic MCAS: "Idiopathic" bivuga "nta mpamvu iboneka." Abenshi mu barwayi ba MCAS bafite ubwo bwoko. Ibi bivuze ko nta mpamvu yihariye ituma utwo turemangingo tw’umugongo twitwara nabi. Ibimenyetso bishobora kugaragara ku bintu bishya igihe icyo ari cyo cyose.

Ni ibihe bimenyetso bishobora kugaragara ku ndwara ya MCAS?

Imwe mu mbogamizi zikomeye kuri MCAS ni uko ibimenyetso bitandukanye cyane kandi bishobora kugira ingaruka ku mikorere y’umubiri myinshi icyarimwe.

Kwitaho cyane: Ihungabana rya Anaphylactic

Ibimenyetso bya anaphylaxis:

• Kugorwa no guhumeka, kumva umuhogo wawe ufunganye
• Kubyimba iminwa, ururimi, cyangwa isura
• Umutima utera vuba cyane.
• Kugabanuka gutunguranye k'umuvuduko w'amaraso
• Kuzungera cyane no gucika intege
• Kuruka no gucibwamo
• Guturika no kurwara uduheri ku mubiri wose

Niba ubonye kimwe cyangwa byinshi muri ibi bimenyetso, ntutinde. Hamagara imbangukiragutabara ako kanya cyangwa ujye mu bitaro bikuru by’ubutabazi bwihuse (ETU) by’ibitaro biri hafi yawe.

Namenya nte ko mfite MCAS?

Gusuzuma MCAS bishobora kugorana gato kuko ibimenyetso biratandukanye cyane. Muganga wawe akunda gushaka ibintu bitatu by'umwihariko.

1. Ibimenyetso: Kuba hariho ibimenyetso bihora bisa n'iby'ubwivumbure mu mubiri mu buryo bubiri cyangwa burenze (urugero: uruhu n'amara).

2. Ibizamini: Ingero z'amaraso cyangwa inkari zifatwa iyo ibimenyetso bigaragaye zigaragaza urugero rwinshi rw'imiti nka ``tryptase'' na ``histamine'', birekurwa n'uturemangingo twa mast.

3. Uburyo bwo kuvura: Ibimenyetso biragabanuka iyo uhawe imiti ibuza imikorere y'uturemangingo twa mast, nka antihistamines.

Iyo ibi bintu bitatu byose byujuje, muganga ashobora gukeka ko ari MCAS. Hari igihe MCAS iherekezwa n'indwara yitwa ``(POTS)`` - Postural Orthostatic Tachycardia Syndrome. Iki ni cyo gihe umutima utera cyane iyo uhagaze.

Ivurwa ite?

Nta muti uraboneka wa MCAS. Ariko ibimenyetso birashobora kugenzurwa neza kandi ubuzima busanzwe bugashobora kugerwaho. Ubuvuzi bufite intego ebyiri z'ingenzi.

1. Kwirinda ibintu bitera indwara: Ikintu cy'ingenzi ni ukumenya icyagutera indwara no kucyirinda.

2. Kugenzura ibimenyetso ukoresheje imiti: Muganga azakwandikira imiti itandukanye.

• Imiti igabanya ubukana bwa H1 na H2: Imiti nka Cetirizine, Loratadine, Famotidine.
• Ibitera imbaraga mu guhagarara kw'uturemangingo twa Mast: Imiti ibuza irekurwa ry'imiti iva mu turemangingo twa Mast.
• Inhibitors za Leukotriene: Ibiyobyabwenge nka Montelukast.
• Ku bibazo byihutirwa: Niba hari ibyago byo kugira anaphylaxis, abaganga bagira inama yo guhora ushyira inshinge zikora (nk'iya EpiPen) ziriho `(epinephrine)` hafi.

Ibintu ugomba kuzirikana mu gihe ubana na MCAS

Kubana na MCAS bishobora kugorana, ariko iyo uyobowe neza , ushobora kubaho neza n'iki kibazo.

• Indyo: Hari ibiryo bishobora gutera MCAS. Witondere cyane cyane ibiryo birimo histamine nyinshi (foromaje itekeshejwe, amafi yo mu macupa, inyanya, epinari, shokora). Ni byiza kugisha inama muganga wawe no kubonana n'inzobere mu mirire kugira ngo agutezeho gahunda y'imirire ikubereye.
• Kugabanya stress: Stress ni imbarutso ikomeye ya MCAS. Kubwibyo, ni ngombwa cyane kugumisha mu mutwe wawe utuje. Ibintu nko gutekereza cyane, yoga, no gukora ibintu ukunda cyane bishobora gufasha.
• Shaka ubufasha: Vugana n'umuryango n'inshuti ku kibazo cyawe. Bishobora kandi kuba ingirakamaro kwinjira mu matsinda y'abaterankunga hamwe n'abantu bahura n'ibibazo nk'ibyo.
• Gushyikirana na muganga wawe buri gihe: Vugana na muganga wawe buri gihe kandi uhindure gahunda yawe yo kuvura uko bikenewe.