Unonzwa wakaneta nguva dzese, uchinzwa seusina hupenyu, uye ruvara rweganda rako rwuri kuchinja zvishoma nezvishoma here? Pamwe une chishuwo chinoshamisa chemunyu. Tinowanzo furatira zviratidzo zvakadaro sezvinowanzoitika. Zvisinei, izvi zvinogona kuva zviratidzo zvechirwere chiri mumuviri wedu chisingawanzoitiki, asi zvakakosha zvikuru kuchiziva nemazvo. Nhasi tiri kutaura nezvechirwere chisingawanzoitiki, asi kana chikarapwa nemazvo, unogona kurarama hupenyu hwakajairika. Ndicho chirwere cheAddison .
Zvichitaurwa zviri nyore, chii chinonzi chirwere cheAddison?
Zvakanaka, ngatitsanangurei izvi zviri nyore. Tine magland maviri madiki, akaita setriangle, akaita sengowani, pamusoro peitsvo dzedu. Tinoadaidza kuti magland eadrenal . Aya ndiwo chikamu chakakosha chehurongwa hwedu hwe endocrine.
Chirwere cheAddison chirwere apo adrenal glands haigadzi mahormone maviri akakosha zvakakwana, cortisol nealdosterone .
Tinoda mahormone maviri aya chii?
- Cortisol: Iyi ihormone inokosha muhupenyu. Inobatsira miviri yedu kubata nekushushikana, senge patinorwara, patinoita tsaona, kana kuvhiyiwa. Inobatsirawo kudzora BP, kurova kwemoyo, mashandiro emuviri, uye huwandu hweshuga muropa.
- Aldosterone: Homoni iyi inobatsira kuenzana kwemaminerari e sodium (munyu) ne potassium mumiviri yedu. Inodzorawo huwandu hwemvura inobuda muitsvo dzedu seweti. Izvi zvinokanganisawo zvakananga BP yedu.
Chirwere cheAddison chinozivikanwawo seprimary adrenal insufficiency . Pane chimwe chirwere chakafanana nacho, chinonzi secondary adrenal insufficiency . Mumamiriro ezvinhu aya, pituitary gland iri muuropi haiburitse hormone yakakwana yeACTH , iyo inosimudzira adrenal glands kuti igadzire cortisol. Asi nhasi tiri kunyanya kutaura nezvedambudziko rinowanikwa muadrenal glands pachadzo.
Musiyano uripo pakati pechirwere cheAddison nechirwere cheCushing
Ungangovhiringidzika nemazita maviri aya. Aya maviri mamiriro ezvinhu akasiyana zvachose.
| Hunhu | Chirwere cheAddison | Chirwere cheCushing |
|---|---|---|
| Dambudziko guru | Kusakwana kwe cortisol (uye aldosterone) mumuviri. | Kuwedzera kwecortisol mumuviri (hypercortisolism). |
| Zvinhu zvakajairika | Kudzikira kwehuremu, kusviba kweganda, kuderera kweBP. | Kuwedzera huremu, kumeso kwakatenderera, BP yakakwira. |
Ndiani ane mukana mukuru wekuwana chirwere ichi? Chinowanikwa kakawanda sei?
Kunyangwe chirwere cheAddison chichigona kubata vanhu vemazera ese, chinonyanya kuitika kuvanhu vane makore ari pakati pe30 ne50 .
Ichi chirwere chisingawanzoitiki . Semuenzaniso, muAmerica, chirwere ichi chinobata munhu mumwe chete pavanhu zana rezviuru. Asi kune vanhu vane chirwere ichi munyika medu futi.
Kune vanhu vari panjodzi huru yekubatwa nechirwere ichi. Ava ndivo vanhu vane zvimwe zvirwere zve autoimmune . Kureva kuti, zvirwere umo masoja emuviri wedu anorwisa masero edu. Kana tiine zvirwere zvakadaro, njodzi yekubatwa nechirwere cheAddison yakanyanya.
- Chirwere cheshuga cherudzi rwekutanga
- Kupererwa neropa kwakaipisisa
- Chirwere cheMakuva
- Chirwere chethyroiditis chisingaperi
- Vitiligo - mavara machena paganda
- Myasthenia gravis
Ndezvipi zviratidzo zvechirwere cheAddison?
Muchirwere cheAddison, kukuvara kweadrenal glands kunowanzoitika zvishoma nezvishoma, nekufamba kwenguva. Nokudaro, zviratidzo zvinoonekwa zvishoma nezvishoma. Zviratidzo izvi zvinogona kusiyana kubva pamunhu kusvika pamunhu.
| Zviratidzo zvinowanzoonekwa zvishoma nezvishoma | |
|---|---|
| Chinhu chinonyanya kuzivikanwa | Kuneta kusingaperi uye kuneta kunowedzera zvishoma nezvishoma, kusingatsananguriki. |
| Kuchinja kweganda | Kuonekwa kweganda rakaita ruvara rwakanyanya, kunyanya munzvimbo dzine mavanga, ganda rakakombama (senge muhapwa, muzvidya), uye mumazino. |
| Sisitimu yekugaya chikafu | Kurwadziwa kwemudumbu, kuda kurutsa, kurutsa, manyoka, kushaya chido chekudya, uye kudzikira kwehuremu. |
| Zvimwe zvinhu | Kurwadziwa kwetsandanyama nemapfundo, kupera mvura mumuviri, dzungu kana wakamira (nekuda kweBP yakaderera), kushatirwa, kuora mwoyo, kuda munyu zvakanyanya, uye shuga shoma muropa (hypoglycemia). |
Vakadzi vanogonawo kuona zviratidzo zvakaita sekuenda kumwedzi zvisina kurongeka, kurasikirwa nebvudzi mumuviri, uye kudzikira kwechido chebonde.
Mamiriro ezvinhu epanjodzi anoda kutarisirwa: Dambudziko reAddisonian
Dzimwe nguva, kunyanya mushure mehutachiona hwakakomba, tsaona, kana kushushikana kwakanyanya, zviratidzo izvi zvinogona kungoerekana zvanyanya kuipa. Izvi zvinonzi Addisonian Crisis kana acute adrenal failure . Iyi idambudziko rehutano rinoda kurapwa nekukasika uye rinogona kutoisa hupenyu panjodzi!
Zviratidzo zvedambudziko reAddisonian:
- Kusasimba kusingatsungiririki, kunoshamisa.
- Kurwadziwa kwakakomba kwepazasi pemusana, mudumbu, kana makumbo kamwe kamwe.
- Kuchinja kwepfungwa kwakadai sekusagadzikana, kuvhiringidzika, uye kunzwa kutya.
- Kurutsa kwakanyanya uye manyoka (izvi zvinogona kukonzera kushaya mvura mumuviri nekukurumidza).
- Kuderera kweropa kwakaderera zvakanyanya.
- Kurasikirwa nepfungwa.
Kana iwe kana mumwe munhu waunoziva akasangana nezviratidzo izvi, kurumidza kumuendesa kuchipatara chiri pedyo neEmergency Department (ETU).
Ndezvipi zvikonzero zvechirwere cheAddison?
Chikonzero chikuru uye chinonyanya kukosha chechirwere cheAddison imhinduro ye autoimmune.. Zvichitaurwa zviri nyore, sisitimu yedu yekudzivirira (immune system) inorwisa nekukanganisa chikamu chekunze cheadrenal glands edu (adrenal cortex). Chikonzero chaicho nei izvi zvichiitika hachisati chazivikanwa. Zviratidzo zvinotanga kuoneka mushure mekunge anenge 90% emaglands aya aparadzwa. Izvi zvinogona kutora mwedzi, kana kunyange makore.
Izvi ndizvo zvinokonzera 75% yevarwere veAddison.
Zvimwe zvikonzero zvisingawanzoitiki:
- Chifuva: Ichi chaive chikonzero chikuru kare. Chichiri chikonzero chikuru munyika dzichiri kusimukira.
- Kutapurirana kwezvirwere: Kutapurirana kwezvirwere zvine chekuita neHIV/AIDS uye hutachiona hwefungus.
- Kenza: Kupararira kwemasero ekenza kubva kune dzimwe nzvimbo kuenda kumatumbu eadrenal.
- Kubuda ropa muadrenal glands.
- Kuvhiyiwa kubviswa kweadrenal glands.
- Amyloidosis: Chirwere umo rudzi rweprotein runoungana munhengo dzemuviri dzodzikuvadza.
Nzira yekuongorora chirwere ichi? (Kuongororwa)
Nekuti zviratidzo zvinouya zvishoma nezvishoma uye zvakajairika kune zvimwe zvirwere zvakawanda, chirwere cheAddison chinogona kuoma kuona pakutanga. Kazhinji, chirwere ichi chinowanikwa "zvisingatarisirwi." Vanachiremba vanogona kufungidzira izvi kana vakawana sodium yakaderera uye potassium yakawanda muropa panguva yekuongororwa kweropa nguva dzose kwechimwe chirwere. Zvakare, hyperpigmentation yeganda chiratidzo chikuru chinoita kuti munhu afungidzire chirwere ichi.
Kana chiremba wako achifungidzira izvi zvichibva pazviratidzo zvako, acharaira mimwe miedzo yakawanda kuti asimbise chirwere chacho.
Miedzo yekuongorora chirwere:
- Kuongororwa kweropa: Kuongororwa kweropa kunoyera huwandu hwemahormone e sodium, potassium, cortisol, uye ACTH. Muchirwere cheAddison, cortisol yakaderera uye huwandu hweACTH hwakakwira.
- Kuongororwa kweACTH: Iyi ndiyo bvunzo huru inoshandiswa kusimbisa chirwere. Muongororo iyi, hormone yeACTH yakagadzirwa inopihwa sejekiseni, uye huwandu hwecortisol muropa rako hunoyerwa mushure meawa imwe chete. Kana adrenal glands yako yakanaka, huwandu hwecortisol yako hunofanira kuwedzera. Zvisinei, kana zvikasadaro, zvinosimbisa kuti adrenal glands yako haisi kushanda zvakanaka.
- Kuongororwa kwehypoglycemia kunokonzerwa ne insulin: Kuongororwa uku kunoitwa kuti uone kana zviratidzo zvako zvichikonzerwa nedambudziko ne pituitary gland.
- CT scan: CT scan inogona kuitwa kuti ione kana adrenal glands yako yakakuvara, ine utachiona, kana kuti saizi yayo yakatetepa.
Inorapwa sei?
Nzira huru yekurapa chirwere cheAddison ndeyekuti,Kurapa Nekutsiva Mahormone (HRT) inzira yekutsiva mahormone asina kukwana mumuviri kuburikidza nemapiritsi ekugadzira.
Nekuti ichi chirwere chisingaperi, uchafanira kutora mushonga uyu kweupenyu hwako hwese .
- Mushonga unonzi hydrocortisone unopiwa panzvimbo pehomoni inonzi cortisol .
- Mushonga unonzi fludrocortisone unopiwa panzvimbo pehomoni inonzi aldosterone .
Chipimo chemishonga iyi chinosiyana kubva pamunhu kusvika pamunhu. Zvakare, chiremba wako anogona kuwedzera chipimo chako kwenguva pfupi kudzivirira dambudziko reAddisonian kana ukasangana nechiitiko chinoshungurudza, senge hutachiona, tsaona, kana kuvhiyiwa.
Kana uri kutora fludrocortisone, chiremba wako achakukurudzira kuti uwedzere munyu mukudya kwako, kunyanya panguva yekupisa, kudikitira uye mushure mekurovedza muviri kwakaoma.
Kurarama nechirwere ichi uye zvaunofanira kuita
Kana munhu ane chirwere cheAddison akarapwa zvakanaka, anogona kurarama hupenyu hwakanaka uye hwakajairika . Zvisinei, zvakakosha kuti munhu arambe achitora mushonga wake nemazvo.
Kana mushonga wacho wakanyanya kukwira, zvinogona kukonzera matambudziko akadai sekufuta, chirwere cheshuga cherudzi rwechipiri, osteoporosis, uye BP. Saka, zvakakosha kuti ugare uchiona chiremba wako (kazhinji chiremba we endocrinologist) uye uedze bvunzo dzinodiwa kuti mushonga wacho urambe wakakodzera.
Zvinhu zvaunofanira kuita kuti uzvichengetedze:
- Gara wakapfeka kadhi reID kana bracelet/necklace yekuzivisa nezvekurapa. Izvi zvichabatsira vashandi vekurapa kuziva kuti une chirwere cheAddison kana ukarasikirwa nepfungwa panguva yenjodzi.
- Taura nachiremba wako nezvekuva nejekiseni recortisol kana paine emergency. Zvakare, dzidzisa mumwe wemumhuri yako kana mumwe waunoda mashandisirwo anoitwa jekiseni iri.
- Bvunza chiremba wako zvekuita kana uchirwara kana kuti uri pasi pekushushikana kwakanyanya. Muzviitiko zvakadaro, mwero wemushonga wako ungada kugadziriswa.
- Ramba uchienda kunoona chiremba wako.
Kuziva kuti une chirwere chisingaperi kunogona kushungurudza mupfungwa. Asi mashoko akanaka ndeekuti chirwere cheAddison chinodzorwa zvakanaka nemishonga. Chinhu chakakosha ndechekugara uchionana nachiremba wako uye kuwana kurapwa kwaunoda.
Mharidzo Yekuenda Nayo Kumba
- Chirwere cheAddison chirwere apo adrenal glands haigadzi mahormone akakwana e cortisol ne aldosterone.
- Zviratidzo zvikuru zvinosanganisira kuneta kusingaperi pasina chikonzero chakajeka, kusviba kweganda nematadza, uye kuda chikafu chine munyu zvakanyanya.
- "Dambudziko reAddisonian" idambudziko rinotyisidzira hupenyu rinoda kurapwa nekukasika.
- Kurapa kwacho ndekwekutora mapiritsi emahormone mashoma kweupenyu hwese.
- Kana ukarapwa zvakanaka, unogona kurarama hupenyu hwakanaka uye hwakajairwa, asi zvakakosha kuti ugare uchitaurirana nachiremba wako.
- Kana uine chirwere ichi, zvakakosha kuti ugare wakapfeka kadhi rekuzivisa nezvekurapa kana bracelet uye uve nehurongwa hwekukurumidzira.
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