Chiremba wako akakuona here kuti une kenza yemazamu iwe kana mumwe munhu waunoda? Saka unofanira kunge wakanzwa izwi rekuti 'chemotherapy'. Zvakajairika kuti unzwe kutya uye kunetseka kana ukanzwa izvi. Asi kana tikaziviswa zvakanaka nezvemishonga iyi, kutya ikoko kunogona kuderedzwa zvakanyanya. Saka, imwe yemishonga inonyanya kukosha inoshandiswa mukurapa chemotherapy inonzi anthracyclines . Nhasi, tichataura nezvazvo zviri nyore, nenzira yaunogona kunzwisisa.
Mushonga uyu unoshanda sei mumuviri?
Zvichitaurwa zviri nyore, anthracyclines rudzi rwemishonga inorwisa mabhakitiriya inobatsira kuuraya masero ekenza. Asi haina kufanana nemishonga inorwisa mabhakitiriya yatinotora padzihwa kana furuu. Inogadzirwa nerudzi rwefungus inonzi Streptomyces, inogara muvhu.
Funga nezvesero rekenza semuchina wekutora mifananidzo unoita makopi usingadzoreki. Muchina uyu unoramba uchigadzira zviuru zvemakopi awo. Aya ndiwo maitiro anoita bundu uye kukura kwaro. Zvinoitwa neanthracyclines ndezvekuti vanobatanidza ku 'master copy' yeDNA iri mumuchina iwoyo wekutora mifananidzo. Ipapo havazokwanisi kugadzira makopi matsva. Izvi zvinoreva kuti kugona kwemasero ekenza kupatsanurana nekukura nekukurumidza kunomira zvachose.
Mushonga uyu unowanzopihwa iwe sejekiseni kana semushonga wesaline mutsinga (inopinzwa mutsinga kana kuti mutsinga yeropa). Chiremba wako ndiye achasarudza kuti mushonga unofanira kutorwa zvakadini uye kuti unofanira kuramba uchirapwa kwenguva yakareba sei zvichienderana nedanho uye mamiriro egomarara rako.
Kazhinji, kana kenza yemazamu iri muchikamu chekutanga, kuvhiyiwa kunoitwa kubvisa bundu. Zvadaro, chemotherapy inopihwa kuti iparadze zvachose masero madiki ekenza, asingaoneki angave achiri mumuviri. Tinodaidza izvi kuti "Adjuvant Chemotherapy" . Izvi zvinoderedza zvikuru mukana wekuti kenza idzoke. Anthracyclines ndeimwe yemishonga mikuru inoshandiswa mu "Adjuvant Chemotherapy".
Mishonga yeanthracycline inoshanda zvakadii?
Ongororo dzakawanda dzakaratidza kuti mishonga yekurapa ine anthracyclines inobudirira zvishoma pane mishonga isina mishonga iyi.
Mune imwe ongororo huru, vakadzi vanopfuura 4,000 vane kenza yemazamu iri padanho rekutanga, avo vaiva nenjodzi huru yekudzokororwa, vakakamurwa kuita mapoka maviri uye vakapihwa marapirwo maviri.
1. Kirasi yeAnthracycline (TaxAC):Vanhu ava vakapihwa mimwe mishonga yechemotherapy pamwe chete neanthracyclines.
2. Boka risina Anthracycline (TC): Vanhu ava vakapihwa musanganiswa wemishonga yakasiyana yechemotherapy isina anthracycline.
Mushure mekuona mapoka ese ari maviri kwemakore angangoita matatu, vaongorori vakatarisa kuti vakararama kwenguva yakareba sei vaine hutano vasina kenza. Zvakabuda zvaive zvinotevera:
- Muboka reanthracycline (TaxAC), 92.4% yegomarara harina kudzoka.
- Muboka renon-anthracycline (TC), 91.7% yegomarara harina kudzoka.
Mhedzisiro iyi inoratidza kuti, kunyange hazvo mutsauko wacho usiri mukuru, kurapwa ne anthracycline kunogona kuderedza zvishoma njodzi yekudzoka kwekenza.
Pane migumisiro yakaipa here yekurapwa uku?
Ehe, sekurapa kwechemotherapies, anthracyclines inogona kukonzera migumisiro yakaipa. Asi havasi vese vanoiwana, uye yakawanda yacho inogona kudzorwa. Chiremba wako achakwanisa kukupa mazano panyaya idzi.
| Rudzi rwemhedzisiro yakaipa | Zviratidzo zvinogona kuitika |
|---|---|
| Migumisiro Yakaderera Kusvika Pakati Nepakati | |
| Zvinhu zvakajairika | Kurutsa uye kuda kurutsa, dzihwa nefivha, manyoka, kurwadziwa mudumbu, kurwadziwa kwemuviri, kuneta. |
| Ganda nenzara | Mapundu eganda, kuvaviwa, kuchinja ruvara rwenzara, kuchinja ruvara rweganda. |
| Mimwe migumisiro | Kuchinja ruvara rweweti (tsvuku), kushaya chido chekudya, kusanzwa chiedza, kumira kuenda kumwedzi, uye kudzikira kwehuwandu hwembeu muvarume. |
| Zvine chekuita neropa | Kubuda ropa, kudzikira kwemasero machena eropa (izvo zvinowedzera njodzi yekutapukirwa), uye kudzikira kwemubofu. |
Ziva migumisiro yakaipa
Mhedzisiro huru uye yakakomba yemishonga iyi injodzi yekukuvara kwemoyo. Kana mishonga iyi ikashandiswa kwenguva yakareba, pane njodzi yezvirwere zvakaita sekushaya simba kwemoyo, izvo zvinogona kunetesa tsandanyama dzemwoyo. Uyewo, mamwe maanthracyclines ane njodzi diki kwazvo yekubatwa nerumwe rudzi rwekenza, senge leukemia, mune zvisingawanzoitiki.
Nekuda kwenjodzi idzi, chiremba wako wekenza nechiremba wemwoyo vachashanda pamwe chete kuti vaongorore mashandiro emoyo wako panguva yese yekurapwa kwako kuti vaderedze kukuvara kungangoitika. Saka usatya izvi.
Izvi zvakakodzera here kune mamwe marudzi ekenza yemazamu?
Ehe. Hadzisi dzese kenza dzemazamu dzakafanana. Saka, chiremba wako ndiye achasarudza kurapwa kwakakunakira. Izvi zvinoenderana nezvinhu zvakati wandei:
- Danho regomarara
- Kana kenza yacho iine hutachiona hwemahormone (Hormone-receptor status)
- HER2 mamiriro ekenza
- Kana kenza yakapararira kusvika kuma lymph nodes
- Zera rako nehutano hwako hwese
Semuenzaniso, kana munhu ava nemakore anopfuura makumi matanhatu, ane BP yakakwira, uye akamborwara nechirwere chemwoyo, chiremba anogona kukurudzira kurapwa kusina anthracyclines.
Ongororo yakaratidza kuti vanhu vane mhando dzekenza dzinokatyamadza, dzakadai sedzisina mativi matatu, uye avo vane kenza yakapararira kuma lymph nodes vanobatsirwa zvikuru nekurapwa ne anthracycline.
Chii chinoitika kana kenza ikasagona kurapwa nemishonga inonzi anthracyclines?
Dzimwe nguva, nekufamba kwenguva, masero egomarara anogona kuramba mishonga iyi, zvichireva kuti mishonga yacho haishande. Usazvidya moyo kana izvi zvikaitika. Kana izvozvo zvikaitika, kune mimwe mishonga yakasiyana uye nzira dzekurapa dzinogona kushandiswa nachiremba wako.
Mimwe mienzaniso ndeiyi:
- Capecitabine (Xeloda)
- Eribulin (Halaven)
- Gemcitabine (Gemzar)
- Vinorelbine (Navelbine)
- Mishonga yemazuva ano yakaita sema antibody drug conjugates
Kunewo mishonga yepamusoro iripo, yakadai sekurapa nemishonga yakanangana nezvirwere uye immunotherapy. Chinhu chakakosha ndechekugara uchitaura nechikwata chako chekurapa.
Mharidzo Yekuenda Nayo Kumba
- Anthracyclines imhando yemishonga ine simba uye inoshanda yechemotherapy inoshandiswa pakurapa kenza yemazamu.
- Basa ravo guru nderekukanganisa DNA yemasero ekenza, zvichivadzivisa kupatsanuka nekukura.
- Kufanana nemishonga yese, kune zvimwe zvinokanganisa. Kunyanya nekuda kwezvingangoitika pamoyo, zvakakosha kuti munhu arapwe achitarisirwa nachiremba zvakanyanya.
- Sarudzo yekuti uchapihwa anthracyclines here kana kuti kwete ichaitwa mushure mekufunga nezvezvinhu zvakawanda, zvakaita serudzi rwegomarara rako uye hutano hwako.
- Usambotya kutaura pachena nachiremba wako nezvekurapa kwako, migumisiro yechirwere, kana chero mibvunzo, kutya, kana zvinokunetsa. Kuziva kwakakodzera ndicho chombo chakanakisisa chekukunda hondo iyi.
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