Vanachiremba pavakasimbisa kuti une kenza yemazamu, ndinogona kufungidzira kuti unofanira kunge wakanzwa kutya, kushamisika, uye kusuruvara sei. Pane mibvunzo yakawanda inouya mupfungwa panguva yakadaro. Asi kana chiremba wako akataura izwi rakaita sekuti 'HER2-Positive', zvinofanira kunge zvakaita kuti pfungwa dzako dzinyanye kunetseka. "Izwi iri chii? Rinoreva here kuti mamiriro angu akakomba?" Zvakajairika kuti zvinhu chiuru zviuye mupfungwa. Ndosaka nhasi tichataura nezvechirwere ichi che 'HER2-Positive', zvinoreva chii, uye kuti ndeapi marapirwo acho nenzira iri nyore yaunogona kunzwisisa.
Chii chinonzi 'HER2'?
Zvichitaurwa zviri nyore, HER2 ipuroteni inobatsira kukura kwemasero emazamu mumuviri wedu. Zita rayo rakazara ndi ``Human Epidermal Growth Factor Receptor 2``. Puroteni iyi inowanikwa mumasero emazamu emunhu ane hutano nehuwandu hwakatarwa, hunodzorwa. Inobatsira masero kupatsanurana nekukura nenzira yakarongeka.
Zvisinei, mune dzimwe kenza dzemazamu, nekuda kwekusakwana kwejini rinogadzira puroteni yeHER2, puroteni iyi inogadzirwa yakawandisa. Zvakafanana nekutsika accelerator yemotokari. Zvadaro, sekunge mota iri kufamba nekukurumidza, masero ekenza aya anotanga kupatsanurana nekukura nekukurumidza, pasina kudzora. Chikonzero chikuru chinoita kuti kenza iwedzere kuipa ndechekugadzirwa kwakanyanya kwepuroteni.
Saka, kana kenza yako iri ' HER2-positive ', zvinoreva kuti pane puroteni iyi yekukura inonzi HER2 yakawandisa pamusoro pemasero ako ekenza.
Ndingaziva sei kana ine HER2-positive?
Kana uchifungidzira kuti une kenza yemazamu, chiremba wako angangokurudzira kuti uitwe biopsy. Sezvaungayeuka, izvi zvinosanganisira kutora chidimbu chidiki chenyama wochitumira kurabhoritari kuti chiongororwe. Sampuro yenyama iyi inozoongororwa kuti ione rudzi chairwo rwekenza.
Chinhu chikuru chinotariswa muongororo iyi iHER2 status. Zvakare, chimwe chinhu chakakosha chinotariswa. Kureva kuti kenza inobatwa nemahormone here kana kuti kwete. Kureva kuti kenza inokura nekuda kwemahormone `(Estrogen)` uye `(Progesterone)`. Mushure mekutarisa zvese izvi, chiremba anosarudza kuti ndeipi nzira yekurapa yakakodzera uye inobudirira kwauri.
Ngatitsanangurei zvishoma nezve zvatiri kuyedza.
| Chiratidzo | Izvozvo zvinorevei? |
|---|---|
| Mamiriro eHER2 | Masero egomarara anoongororwa kuti aone kana aine HER2 protein yakawandisa (yakanaka) kana kuti kwete (yakaipa). Kana iri positive, zvinoreva kuti protein iyi inobatsira masero egomarara kukura nekukurumidza. |
| Mamiriro eHormone Receptor | Vanotsvaga kana masero ekenza aine mareceptor ehormone inonzi estrogen kana progesterone. Kana aya ari mahormone akanaka, mahormone iwayo anobatsira kukura kwekenza. |
Mhedzisiro yebvunzo idzi ndiyo icharatidza rudzi rwegomarara raunaro. Semuenzaniso, HER2-positive kana Hormone Receptor-negative. Ruzivo urwu rwese rwakakosha mukukubatsira kugadzira hurongwa hwako hwekurapa .
Ndiani anowana kenza ine HER2-positive? Ine njodzi here?
Kenza yemazamu ine HER2-positive inogona kuitika kuvakadzi pamwe chete nevarume, uye kashoma kuvarume. Inowanzoitika kuvakadzi vari pasi pemakore makumi mashanu. Chikonzero chaicho hachisati chazivikanwa.
Zvino ngatisvikei pamubvunzo mukuru uri mupfungwa dzako: Izvi zvine njodzi here?
Chokwadi ndechekuti, kenza dzeHER2-positive dzinogona kunge dzichikura zvishoma. Izvi zvinoreva kuti masero ekenza aya ane katsika kekupatsanura kana kupararira nekukurumidza.
Asi, musavhunduka! Izvi ndizvo zvamunofanira kurangarira. Ehe, rudzi urwu rwegomarara runogona kukurumidza. Asi mishonga inoshanda zvikuru uye yakanangana yakagadzirwa nhasi iyo yakakodzera. Saka, hapana chikonzero chekutya izwi rekuti "kukurumidza".
Kurapwa uye tariro yekupora
Aya ndiwo mashoko akanakisa munyaya ino. Makore angangoita makumi maviri apfuura, kenza yemazamu ine HER2-positive yaionekwa sechirwere chakaoma uye chakakomba kurapa. Asi nekufambira mberi kwesainzi yezvekurapa, mamiriro acho achinja zvachose nhasi.
Masayendisiti akawana mishonga yakasiyana-siyana inogona kumisa nekudzivirira mashandiro epuroteni iyi yeHER2. Izvi zvinonzi " targeted therapy.")`. Kutaura chokwadi, mishonga iyi inoenda zvakananga kuHER2 protein iripo yakawandisa, ichivhara chiratidzo chinogamuchirwa nemasero ekenza kuti "akure nekukurumidza." Izvi zvakafanana nekuisa mabhureki pamotokari iri kumhanya.
Nekuda kwemishonga iyi yakanangwa, mukana wekuti munhu ane kenza yemazamu ine HER2-positive apore zvachose wakwira zvakanyanya, zvichienderana nehuwandu hwekurapa kwekenza dzinoshandiswa nemahormone.
Chii chinoitika mushure mekurapwa?
Mushure mekupedza kurapwa, chiremba wako acharamba achikutarisa. Kashoma, kenza inogona kudzoka kana kupararira kune dzimwe nhengo dzemuviri. Kana izvi zvikaitika, chiremba wako achaita imwe biopsy. Izvi zvinodaro nekuti mhando yekenza inogona kuchinja nekufamba kwenguva. Semuenzaniso, kenza yaimbova neHER2-positive inogona kudzoka yova HER2-negative. Saka, kurapwa kunogara kuchienderana nemamiriro azvino.
Saka, bvisa kutya kwako. Ehe, izwi rekuti kenza rinotyisa. Asi HER2 -Positive chirwere chinorapika uye chinorapika nhasi.
Mharidzo Yekuenda Nayo Kumba
- Kenza yemazamu ine HER2-positive inoitika apo masero ekenza anoburitsa puroteni yakawanda (HER2) inokurumidza kukura.
- Dambudziko iri rinoonekwa nekuongorora sampuli yenyama kubva ku biopsy yako.
- Kunyange hazvo mhando iyi yegomarara ichikura nekukurumidza, hapana chikonzero chekuitya.
- Mazuva ano, kune nzira dzekurapa dzakagadzirwa dzinobudirira zvikuru nechinangwa ichi. Nekuda kweizvozvo, mikana yekupora yakakura kwazvo.
- Taura pachena nachiremba wako nezvemibvunzo, kutya, kana kusava nechokwadi kwaungave uinako. Ndipo paunowana ruzivo rwakarurama uye zororo rakanakisisa.
- Hausi wega. Nepfungwa dzakasimba uye kurapwa kwakakodzera, unogona kukunda dambudziko iri.
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