Kana iwe kana mumwe munhu waunoziva ari kurwara nekenza yemazamu yakanyanya kukura, zvinogona kukubatsira kuti urambe uine ruzivo nezveruzivo rutsva nezvakawanikwa. Masayendisiti nevanachiremba vanogara vachiedza kunzwisisa chirwere ichi zviri nani uye kuwana mishonga mitsva inoshanda. Saka ngatitarisei kuti tariro itsva iyi chii.
Mishonga mitsva inotenderwa
Mishonga mitsva yakati wandei yakatounzwa yakaratidza mhedzisiro inoshanda zvikuru pakurapa kenza yemazamu. Mimwe yemishonga iyi inoshanda nekutarisa mapuroteni chaiwo anodzora kukura kwemasero ekenza.
Zvichitaurwa zviri nyore, mamwe marudzi ekenza yemazamu anokonzerwa nemahormone mumuviri kuti akure. Tinoti idzi "kenza dzinogamuchira mahormone zvakanaka". Zvakare, mamwe masero ekenza haana puroteni inonzi `HER2` pamusoro pawo. Aya anonzi `HER2` negative cancers. Kana uine rudzi urwu rwekenza, mishonga mitsva inogona kuva sarudzo yakanaka kwauri.
Ngatitarisei mimwe yemishonga mitsva iyi patafura iri pazasi.
| Rudzi rweMushonga | Zita reMushonga | Tsananguro iri nyore |
|---|---|---|
| Madhiragi eCDK 4/6 | Palbociclib (Ibrance) Abemaciclib (Verzenio) Ribociclib (Kisqali) | Izvi zvinodzora kupatsanurwa nekukura kwemasero ekenza. Anowanzopihwa pamwe chete nekurapwa nemahormone. Izvi zvinogona kuderedza kupararira kwekenza kwemwedzi yakati wandei. |
| Kurapa nekudzivirira muviri | Sacituzumab govitecan (IMMU-132) | Mushonga uyu unonyanya kurwisa puroteni inonzi `Trop-2` pamusoro pemasero egomarara. Unokurudzirwa zvikuru kune vanhu vakatogamuchira mamwe marapirwo maviri. |
Chinhu chinonyanya kukosha ndechekutaura pachena nachiremba wako nezvekuti mishonga iyi yakakunakira here, kuti ungaiwana sei, uye kuti migumisiro yayo ndeipi.
Tariro itsva dzichiri muchikamu chekutsvagisa
Pamusoro pemishonga iri kubvumidzwa parizvino, kune mimwe mishonga yakawanda iri kutsvakurudzwa. Kunyangwe iyi isiri kushandiswa zvakanyanya, inogona kuva chikomborero chikuru kwatiri mune ramangwana.
Zvinodzivirira PARP
Mishonga iyi inoshanda nekudzivirira kugona kwemasero ekenza kuzvigadzirisa (DNA repair). Yakawanikwa ichibatsira zvikuru kune vanhu vane shanduko mumajini eBRCA1 kana BRCA2, ayo ane chekuita nekenza yemazamu.
Zvinodzivirira Tyrosine Kinase
Iyi mishonga inovharawo ma enzyme anobatsira kukura kwemasero egomarara. Lapatinib (Tykerb) yakatobvumidzwa kuti ishandiswe pakurapa kenza dzine HER2-positive. Mumwe mushonga, Neratinib, wakaratidzwa muchidzidzo chitsva kuti unobatsira varwere kurarama kwenguva yakareba kana vakapihwa mushure me chemotherapy.
Mishonga yeHER2 yakanangwa zvakanyanya
Munhu mumwe chete pavanhu vashanu vane kenza yemazamu ane puroteni yakawandisa inonzi HER2, iyo inobatsira kukura kwemasero ekenza yemazamu. Mishonga inotarisa puroteni iyi iri kugadzirwa zuva nezuva. Semuenzaniso, mushonga weMargetuximab waratidza mhedzisiro yakanaka mukuderedza bundu, uye mushonga weONT-380 waratidza mhedzisiro yakanaka mukurapa kenza yemazamu pasina migumisiro yakawanda.
Kumwe kurapa kwezvirwere zvemuviri
Mishonga iyi inoshanda nekukurudzira masoja edu ekudzivirira chirwere kuti arwise gomarara. Mushonga wekuti `Pembrolizumab` waratidza mhedzisiro yakanaka mukuyedzwa kwekiriniki, kunyanya sekurapa gomarara remazamu rine simba re`Triple-Negative`.
Kunzwisisa kutsva kwekuti kenza inopararira sei
Pamwe chete nemishonga mitsva iyi, masayendisiti ari kuwanawo zvinhu zvitsva nezvekupararira kwegomarara mumuviri wese (metastasis). Kunzwisisa uku kwakakosha zvikuru pakurapwa mune ramangwana.
Fungidzira, taimbofunga kuti kenza inopararira semusoja anobva muuto ari kutiza oenda kunogara panzvimbo itsva. Kureva kuti, sero rimwe chete rekenza rinofamba nemuropa roenda kune imwe nhengo, yakaita sechiropa kana mapapu.
Asi, tsvakiridzo yazvino yakawana kuti, kwete chete, izviMasero egomarara anonzi anofamba ari mapoka , seboka remasoja ari kufamba pamwe chete.
Kuwanikwa uku kwakakosha zvikuru nekuti, kana tangoziva maitiro chaiwo ekenza, zvichava nyore kuti masayendisiti vagadzire mishonga yakanangana inogona kumisa mapoka iwayo. Kureva kuti, kumisa boka kuti risafambe kunogona kushanda zvakanyanya pane kumisa sero rimwe chete.
Ungabatsira sei parwendo urwu?
Nekuwana zvinhu zvitsva izvi, iwewo unogona kuwana mikana yekubatsira muhondo iyi neimwe nzira.
Chinhu chinonyanya kukosha kutaura nachiremba wako. Bvunza kuti, "Pane mishonga mitsva here kana miedzo yekiriniki munyika medu ingandikodzera?" Miedzo yekiriniki zvidzidzo zvinonyatsoongororwa zvinoedza kushanda uye kuchengetedzeka kwemishonga mitsva isati yapihwa kune veruzhinji.
Chiremba wako achakwanisa kutsanangura mabhenefiti, njodzi, uye zvinotarisirwa nekutora chikamu mukuyedza kwakadaro. Zvakakosha kubvunza chiremba wako usati waita chero sarudzo.
Uyewo, tarisa mapoka ekutsigira varwere vegomarara. Anogona kukupa rutsigiro rwepfungwa neruzivo rutsva. Yeuka, hausi wega uri murwendo urwu.
Mharidzo Yekuenda Nayo Kumba
- Mishonga mitsva uye inoshanda zvakanyanya (CDK 4/6 inhibitors, immunotherapy) yava kuwanikwa yekenza yemazamu yakakwira. Iyi inogona kudzora kupararira kwekenza.
- Sainzi iri kufambira mberi zuva nezuva. Kuwanikwa kwekuti kenza inopararira mumapoka, kwete semasero rimwe chete, kwakavhura nzira itsva dzekurapa mune ramangwana.
- Gara uchitaura nachiremba wako nezvemishonga mitsva nemiedzo yekiriniki yakakunakira. Usatende zvese zvaunoona pa internet, tsvaga mazano ekurapa akarurama.
- Hondo iyi yakaoma, asi hausi wega. Masayendisiti nevanachiremba pasi rese vanogara vachitsvaga zvinhu zvitsva zvekubatsira varwere vakaita sewe. Ramba uine tariro.
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