Ko BP yako haisi kudzikira here kunyangwe uchishandisa mushonga? Ngatidzidzei nezve hyperaldosteronism.

Dzimwe nguva unombozvibvunza here kuti, 'Sei BP yangu isingaderere kunyangwe nemishonga?'? Vamwe vanhu vane dambudziko rakafanana. Pane dzimwe nguva pazvinonetsa kudzora BP yavo, kunyangwe mushure mekutora mishonga. Panguva dzakadai, tinofanira kufunga kana paine chikonzero chaicho. Nhasi, tichataura nezvechirwere chinonetsa kuongororwa, asi chinogona kurapwa kana chikarapwa nemazvo. Ndiko hyperaldosteronism .

Chii chinonzi Hyperaldosteronism?

Zvichitaurwa zviri nyore, hyperaldosteronism inoitika kana adrenal glands yako ichiburitsa hormone yakawandisa inonzi aldosterone . Funga nezvazvo nenzira iyi, aldosterone yakaita seinjiniya mudiki anodzora BP yedu. Inobatsira kuchengetedza BP yedu iri padanho rakakodzera nekudzora huwandu hwepotassium nesodium mumiviri yedu.

Zvino ungave uchishamisika kuti, 'Ndezvipi izvi zvinonzi adrenal glands?' Izvi chikamu chehurongwa hwedu hwe endocrine . Zvakafanana nemafekitori madiki anogadzira mahormone akasiyana-siyana anodiwa nemiviri yedu kuti ishande zuva nezuva. Tine maviri eaya ma adrenal glands, ayo ari pamusoro peitsvo dzedu, sechivharo.

Ndeapi marudzi e hyperaldosteronism?

Kune mhando mbiri huru dze hyperaldosteronism.

1. Primary Hyperaldosteronism: Izvi dzimwe nguva zvinonzi Conn's syndrome . Chinoitika pano ndechekuti pane chimwe chinhu chisina kumira zvakanaka nema adrenal glands ako, zvichiita kuti agadzire aldosterone yakawandisa. Funga nezvazvo sekunge pane dambudziko mukati mefekitori uye ari kugadzira zvinhu zvakawandisa.

2. Secondary Hyperaldosteronism: Iri harisi dambudziko neadrenal glands. Idambudziko riri kune imwe nzvimbo mumuviri wako rinoita kuti adrenal glands itange kukurudzirwa uye kutanga kugadzira aldosterone yakawanda. Izvi zvinoreva kuti fekitori iri kushanda kwenguva yakareba nekuda kwesimba rekunze.

Chero zvazvingava, mhedzisiro ndeyekuti huwandu hwealdosterone muropa rako hunokwira, zvichikonzera kukwira kweropa (hypertension) uye huwandu hwepotassium muropa rako hunoderera. Kudzikira uku kwepotassium kunonzi hypokalemia .

Ndiani anonyanya kubatwa nechirwere ichi? Chinowanzoitika sei?

Hyperaldosteronism inonyanya kuonekwa muvanhu vane makore ari pakati pe30 ne50.Uyewo, chirwere ichi chinowanzoitika pakati pevakadzi kupfuura varume.

Zvakaoma kuti vaongorori vataure kuti izvi zvakajairika sei, nekuti dzimwe nguva hazvionekwi zvakanaka. Asi dzimwe ongororo dzinoratidza kuti pakati pe5% ne10% yevanhu vane BP yakakwira vanogona kunge vaine chirwere cheprimary hyperaldosteronism. Nyanzvi dzinofungidzira kuti vanhu vanosvika 25% vane BP yakakwira isingadyirwe nemishonga vanogona kunge vaine chirwere ichi. Saka, hazvisi zvisinganzwisisike, handiti?

Ndezvipi zviratidzo zveHyperaldosteronism?

Zviratidzo zve hyperaldosteronism zvinogona kusiyana kubva pamunhu kuenda kune mumwe, zvichienderana nekuoma kwechirwere. Vamwe vanhu vanogona kunge vasina zviratidzo zvachose , kunyanya kana chirwere chacho chisina kunyanya kuoma.

Zvisinei, chiratidzo chikuru uye chinowanzoonekwa chechirwere ichi iBP yakakwira (BP) , kunyanya BP yakakwira iyo isingagoni kudzorwa zviri nyore kunyangwe nemishonga.

Uyezve, kana ukaona zvimwe zviratidzo, zvinowanzokonzerwa neBP yakakwira kusvika yakanyanya uye/kana potassium shoma muropa (hypokalemia).

Zviratidzo zvinogona kuitika nekuda kweBP yakakwira (BP):

• Musoro
• Dzungu
• Kuchinja kwemaonero
• Kuoma kufema

Zviratidzo zvinogona kuitika nekuda kwekushomeka kwepotassium muropa (hypokalemia):

• Kushaya simba kwetsandanyama - Mune zvimwe zviitiko zvakakomba, chirwere chakafanana nekuoma mitezo kwenguva pfupi chinogona kuitika.
• Kugwinha kwetsandanyama kana kugwinha (Kugwinha kwetsandanyama)
• Kunzwa kusanzwa uye kusanzwa
• Kuneta
• Nyota yakanyanya (izvi zvinonzi polydipsia)
• Kuita weti kakawanda

Zvino wava kunzwisisa, nekuti zvimwe zvezviratidzo izvi zvinowanikwa mune zvimwe zvirwere, dzimwe nguva zvinogona kunonoka kuziva izvi.

Chii chinokonzera izvi?

Zvinokonzera hyperaldosteronism zvinosiyana zvichienderana nekuti ndechekutanga here kana kuti chechipiri. Ngationei kuti zvinoitwa sei.

Zvinokonzera Hyperaldosteronism Yekutanga

Sezvandambotaura, Primary Hyperaldosteronism idambudziko rine adrenal glands ako pachawo, zvichiita kuti agadzire aldosterone yakawandisa.

Chikonzero chikuru cheizvi mabundu asiri ekenza anonzi adrenal adenomas anoumbwa mumatumbu eadrenal . Aya mabundu madiki, asina njodzi, asi anogona kukonzera kuburitswa kwakanyanya kwehomoni aldosterone.

Mukuwedzera, kune zvimwe zvikonzero zvisingawanzoitiki :

• Kuwanda kweadrenal plasia kweimwe divi - Izvi zvinoreva kuti adrenal gland rimwe chete riri kudivi rimwe rinozvimba, rinokura, uye rinoburitsa mahormone akawanda.
• Kansa dzemudumbu dzinogadzira aldosterone - Aya mabundu ekenza. Zvisinei, haawanzoitiki.
• Familyal hyperaldosteronism type 1 - Ichi chirwere chinotorwa kubva kuvabereki kuenda kuvana.

Zvinokonzera Hyperaldosteronism Yechipiri

Chikonzero chikuru che secondary hyperaldosteronism kudzikira kwehuwandu hweropa rinosvika kuitsvo dzako .

Kuti unzwisise kuti izvi zvinoitika sei, unofanira kuziva kuti hormone inonzi aldosterone chikamu cheketani yemahormone anodzora BP yedu. Funga nezvazvo seketani.

Sisitimu iyi inonzi renin-angiotensin-aldosterone system . Inoshanda seizvi:

1. Kana muviri wako uchinzwa BP yakaderera kana kuti sodium shoma muropa rako, itsvo dzako dzinoburitsa enzyme inonzi renin .

2. Renin iyi inoshanduka ichichinja chinhu chinonzi angiotensinogen (chinhu chinotangira angiotensin) chinogadzirwa nechiropa chako kuita angiotensin I. (Angiotensin ihormone inovhara tsinga dzedu dzeropa.)

3. Tevere, iyi angiotensin I inova angiotensin II .

4. Chekupedzisira, iyi angiotensin II ndiyo inoomesa tsinga dzeropa uye inosimudzira ma adrenal glands kuti abudise hormone aldosterone .

Zvino fungidzira, kana nekuda kwechimwe chikonzero huwandu hweropa hunoenda kuitsvo hukadzikira, itsvo dzinofunga kuti, 'Ah, BP yangu yadzikira.' Zvadaro dzinoita kuti system iyi ye renin-angiotensin-aldosterone ishande zvisirizvo. Mugumisiro wacho ndewekuti huwandu hwe aldosterone mumuviri hunowedzera, kunyangwe zvisiri izvo zvinodiwa.

Zvinokonzera zvinogona kuderedza kuyerera kweropa kuenda kuitsvo uye kukonzera hyperaldosteronism yechipiriHeano mashoma:

• Chirwere chetsinga dzeitsvo dzinovhara - senge pombi yemvura yakavharika.
• BP yeitsvo
• Mamiriro ezvinhu apo mvura inoungana mumuviri (edema) , semuenzaniso:
• Kukundikana kwemoyo
• Kurwara kwechiropa
• Nephrotic syndrome chirwere cheitsvo.

Unoona sei izvi?

Chiremba anowanzo ongorora chirwere chehyperaldosteronism kuburikidza nekuongororwa ropa . Zvisinei, vanhu vazhinji havamboonekwa vaine chirwere ichi nekuti kune zvimwe zvikonzero zvakawanda uye zvinhu zvinogona kukonzera BP.

Zvimwe zviratidzo zvinowanzoonekwa zvekuti une hyperaldosteronism zvinosanganisira:

• Kukwira kweropa kusingarapike nemishonga.
• Heano mhedzisiro kubva kumushumo wekuongororwa kweropa rako re electrolyte :
• Sodium yakakwira zvishoma (hypernatremia) .
• Mwero wemagnesium wakaderera zvishoma (hypomagnesemia) .
• Uyewo, mazinga e potassium akaderera (hypokalemia) .

Kana chiremba wako achifungidzira kuti ungave uine hyperaldosteronism zvichibva pazviratidzo izvi, angangoda kuongororwa ropa kaviri: Plasma Renin Concentration (PRC) kana Plasma Renin Activity (PRA) .

• Kana uine chirwere chePrimary Hyperaldosteronism , huwandu hwePRC nePRA yako huchava hwakaderera pane hwakajairwa.
• Kana uine secondary hyperaldosteronism , mazinga aya achava akakwira kupfuura akajairwa.

Pamusoro pezvo, ungangodawo kuongororwa kudzvinyirirwa kwealdosterone . Kuongororwa uku kunosanganisira kukupa huwandu hwakati hwesodium (munyu) nemuromo kana nejekiseni resaline (IV) kwenguva yakati. Zvadaro, sampuro dzeweti yako dzinotorwa mukati memaawa makumi maviri nemana uye huwandu hwealdosterone muweti iyoyo hunoyerwa murabhoritari.

Kana bvunzo idzi dzikaramba dzichiratidza kuti une hyperaldosteronism, chiremba wako anogona kuraira kuti uongororwe zvimwe kuti awane chikonzero. Semuenzaniso, CT scan (computed tomography scan) kuti uone kana bundu risiri rekenza riri kukonzera hyperaldosteronism.Ungakumbirwa kuti uite bvunzo yemifananidzo .

Ndezvipi zvinorapwa izvi?

Kurapwa kwehyperaldosteronism kunoenderana nechikonzero, asi chinangwa chikuru ndechekudzora BP yako .

• Kana paine chirwere che hyperaldosteronism, chirwere chinokonzerwa nebundu re adrenal gland, vanachiremba vanowanzo kurudzira kubviswa bundu iri nekuvhiyiwa . Zvisinei, mune dzimwe nguva, bundu iri rinogona kurapwa nemishonga chete. Kunyangwe mushure mekuvhiyiwa, ungangove uchiri neBP yakakwira, saka ungangoda kunwa mushonga wekudzora dambudziko iri.

• Secondary hyperaldosteronism inorapwa nekudzora BP yako nemishonga, ukuwo ichirapawo chikonzero chacho (semuenzaniso, chirwere chemwoyo) .

Kune mhando dzakasiyana dzemishonga dzinogona kubatsira ne hyperaldosteronism:

• Spironolactone (Spironolactone - Aldactone®)
• Eplerenone (Eplerenone - Inspra®)
• Amiloride (Amiloride - Midamor®)

Chimwe chinhu chekurangarira ndechekuti kushandisa kwenguva refu mishonga inodzivisa aldosterone, yakaita seSpironolactone , kunogona kukonzera mimwe migumisiro yakaipa kuvarume. Semuenzaniso, kusashanda zvakanaka kwenhengo dzemurume uye gynecomastia zvinogona kuitika. Saka, zvakakosha kutaura nachiremba wako nezvemushonga wakakunakira, kuti unofanira kuutora kwenguva yakareba sei, uye kuti migumisiro yacho ndeipi.

Izvi zvinogona kudzivirirwa here?

Kutaura zvazviri, kazhinji, hapana chaunogona kuita kudzivirira chirwere ichi chehyperaldosteronism. Nekuti chinokonzerwa nekuchinja kwemaitiro emukati memuviri wedu. Zvisinei, unogona kuchengetedza hutano hwako hwese nekutevera mararamiro ane hutano, kudya chikafu chakaringana, uye kurovedza muviri.

Chii chiri kufanotaura nezvechirwere ichi?

Kufanotaura kwe hyperaldosteronism kunoenderana nechikonzero.

• Kurwara kwakanyanya kweropa , kana kukaongororwa nekukurumidza uye kukarapwa nemazvo, kunowanzova nemigumisiro yakanaka . Kana bundu rikabviswa, chirwere ichi chinowanzo gadziriswa.
• Hyperaldosteronism yechipiriRemangwana rechirwere rinoenderana nekuti chirwere chiripo (semuenzaniso, chirwere chemwoyo, chirwere chechiropa) chinogona kudzorwa sei.

Matambudziko makuru anogona kuitika nekuda kwehyperaldosteronism matambudziko emwoyo anokonzerwa neBP yakakwira. Izvi zvinosanganisira:

• Kurova kwemoyo zvisina kurongeka - kurova kwemoyo kusina kurongeka.
• Kukwirira kweropa mumoyo wekuruboshwe - kusimba kwemadziro ekamuri rekuruboshwe remoyo.
• Kumira kurova kwemoyo
• Kurohwa

Ndosaka zvichikosha zvikuru kuongorora chirwere ichi nekukurumidza uye kuwana kurapwa kwakakodzera.

Ndinofanira kuona chiremba rini?

Kana wakamboonekwa uine hyperaldosteronism, unofanira kuona chiremba wako nguva nenguva kuti uve nechokwadi chekuti mushonga wawakapihwa uri kushanda nemazvo . Zvakakoshawo kutevedzera mirairo yachiremba wako.

Kana ukaona zviratidzo zvitsva, kana kuti ukaona shanduko yezviratidzo zviripo , zivisa chiremba wako nekukasika.

Chinhu chinonyanya kukosha ndechekuti, kana uine BP yakakwira isingarapike nemishonga, taura nachiremba wako nezvezvinokunetsa, zvakaita sekuti, "Ndingawana hyperaldosteronism here?" Iye anogona kuongorora mamiriro ako uye kukurudzira chero bvunzo dzinodiwa.

Yeuka kuti kune zvakawanda zvinokonzera BP. Hyperaldosteronism chimwe chazvo. Mashoko akanaka ndeekuti chirwere ichi chinorapika.

Mharidzo Yekuenda Nayo Kumba

Zvakanaka, saka ndinovimba wava kunzwisisa zviri nani zvatiri kutaura nezvazvo, Hyperaldosteronism. Heano zvimwe zvinhu zvekurangarira:

• Hyperaldosteronism ihomoni yakawanda inoburitswa neadrenal glands.
• Izvi zvinogona kukonzera BP yakakwira (BP) uye potassium shoma muropa (hypokalemia) .
• Kune mhando mbiri huru: Yekutanga ( dambudziko rine adrenal glands pachayo) uye Yechipiri (kukurudzira adrenal glands nekuda kwedambudziko riri kune imwe nzvimbo).
• Kana uine BP yakakwira isingadzoreki nemishonga , unofanira kunyumwa nezvazvo.
• Izvi zvinoonekwa kuburikidza nekuongororwa kweropa .
• Kurapa kunosanganisira kudzora BP uye kurapa chikonzero chacho .
• Kana zvikaonekwa uye zvikarapwa nekukurumidza, zvinogona kuwanikwa mhedzisiro yakanaka .

Kana muine mimwe mibvunzo nezveizvi, musazeza kubvunza chiremba wenyu. Rambai muine hutano hwakanaka!

Hyperaldosteronism , Hyperaldosteronism, Aldosterone, Kukwira kweropa, BP, Potassium, Adrenal glands, Conn's syndrome