Zvakajairika kunzwa kutya kukuru uye kuzvidya mwoyo kana chiremba wako akakuudza kuti mumwe munhu mumhuri yako, pamwe amai vako kana baba vako vaunoda, vane chirwere cheParkinson's Disease. Kunyangwe hazvo kuchiri kusina mushonga wechirwere ichi, kune mishonga yakawanda inoshanda inogona kubatsira kudzora zviratidzo uye kuchengetedza hupenyu hwakanaka. Saka nhasi, ngatitaurei nezvemishonga iyi, mashandiro ayo, uye zvatinofanira kuziva.
Sei chirwere cheParkinson chichiitika? Chii chinoitika nemishonga?
Zvichitaurwa zviri nyore, chirwere cheParkinson chirwere chetsinga chinokanganisa kufamba kwemuviri. Chinokonzerwa nekurasikirwa zvishoma nezvishoma kwemasero etsinga muuropi, kunyanya muchikamu cheuropi chinonzi substantia nigra chinodzora kufamba. Masero aya etsinga anogadzira neurotransmitter inonzi dopamine .
Funga nezvazvo, kemikari inonzi dopamine inokosha kuti muviri wedu ufambe zvakanaka, sekutyaira mumugwagwa usina kuzara kwemotokari. Muchirwere cheParkinson, kugadzirwa kwedopamine iyi kunoderera, zvichikonzera zviratidzo zvakaita sekufamba zvishoma nezvishoma, kudedera, uye kuomarara.
Saka chinangwa chikuru chemishonga yakawanda yechirwere cheParkinson ndechekudzora mwero wakaderera wedopamine muuropi.
Mishonga inonyanya kushandiswa
Vanachiremba vanowanzo nyora mishonga yakasiyana-siyana kuvarwere vane chirwere cheParkinson, kwete mumwe chete. Ngatitarisei mhando huru dzemishonga.
| Kirasi yeMishonga | Mashandiro Azvo | Ruzivo rwakakosha |
|---|---|---|
| Levodopa neCarbidopa | Levodopa mushonga unoenda kuuropi woshanduka kuita dopamine. Asi nekuti unoparadzwa mumuviri usati wasvika kuuropi, unosanganiswa nemushonga unonzi carbidopa kuti umiswe. | Uyu ndiwo mushonga mukuru uye unoshanda zvikuru wechirwere cheParkinson. Unoshanda zvikuru mukuderedza kunonoka kwekufamba (bradykinesia), kuomarara, uye kudedera. |
| Vadzvinyiriri veDopamine | Izvi zvinokurudzira ma dopamine receptors muuropi uye "zvinoita" se dopamine. Kureva kuti, mishonga iyi inoita zvakafanana ne dopamine. | Inowanzoshandiswa pakutanga kwechirwere kana kuvarwere vadiki, inobatsirawo kuchengetedza kushanda kwelevodopa kwenguva yakareba. |
| MaEnzyme Inhibitors (MAO-B & COMT) | Mishonga iyi inoderedza mashandiro ema enzymes anoputsa dopamine muuropi, zvichiita kuti dopamine irambe iri muuropi kwenguva yakareba. | Izvi zvinopihwa kuti zvibatsire kuwedzera simba re levodopa uye kuti rigare kwenguva refu. |
| Amantadine | Inobatsira kudzora dyskinesia, inova kufamba kusingadzoreki uye kugwinha kunogona kukonzerwa nemishonga yakaita selevodopa. | Kunyangwe pakutanga yakawanikwa semushonga wekurwisa mavhairasi, inobatsirawo kune mamwe matambudziko ekufamba-famba akadai sechirwere cheParkinson. |
| Mishonga yeAnticholinergic | Kana dopamine yaderera, migumisiro yeimwe kemikari inonzi acetylcholine inowedzera. Mishonga iyi inodzivisa migumisiro yayo, ichideredza kudedera uye kuomarara kwetsandanyama. | Zvingabatsira varwere vane kudedera kwakanyanya. |
Chinhu chinonyanya kukosha ndechekuti chiremba wako chete ndiye anogona kusarudza kuti ndeipi yemishonga iyi yaunofanira kupa uye kuti ingani. Zvinoenderana nezera remurwere, rudzi rwezviratidzo, nezvimwe zvinhu zvakawanda.
Tinofanirawo kuziva nezvemigumisiro yemishonga here?
Kufanana nemishonga yese, mishonga yeParkinson inogona kuva nemigumisiro. Izvi zvinosiyana zvichienderana nerudzi rwemishonga. Musazvidya mwoyo, havasi vese vanozowana migumisiro iyi yese. Asi zvakakosha kuti muzvizive.
- Levodopa: Kusvotwa, kurutsa, dzungu, musoro, hope masikati, uye kushaya simba mumuviri zvinogona kuitika pakutanga kwekurapwa. Muvanhu vakuru, kuvhiringidzika, kuona zvinhu zvisipo, kana psychosis zvinogona kuitika.
- Dopamine Agonists: Izvi zvinogona kukonzera kuda kurutsa, hope, muromo wakaoma, kuvhiringidzika, uye kuona zvinhu zvisipo paunotanga kuzvitora. Zvisinei, izvi zvinowanzopera mukati memazuva mashoma.
- Mimwe mishonga: Mimwe mishonga inogona kukonzera migumisiro yakadai semanyoka, kurwadziwa muchipfuva, kushaya hope, kuzvimba kwemakumbo, kuvimbiwa, kana muromo wakaoma.
Yambiro inokosha zvikuru: Usamborega kutora levodopa kana kuderedza mushonga kamwe kamwe usina kubvunza chiremba wako. Kuita izvi kunogona kutungamira kuchirwere chine njodzi zvikuru, chinouraya chinonzi Parkinsonism Hyperpyrexia Syndrome. Chirwere chakakomba chakafanana neNeuroleptic Malignant Syndrome. Kana uchida kurega kutora mushonga chero chikonzero chipi zvacho, iva nechokwadi chekutaura nachiremba wako.
Pane mishonga yezvimwe zviratidzo zvisingabatanidzwi nekufamba here?
Ehe. Chirwere cheParkinson hachisi chirwere chinokanganisa kufamba kwemuviri chete. Asi kune mamwe matambudziko akawanda anouya nacho. Chiremba anogonawo kurapa izvozvo.
| Chiratidzo | Kurapa Kunogona Kuitika |
|---|---|
| Kuzvimba | Mishonga inobatsira kuderedza tsvina, yakaita se polyethylene glycol (yakaita seMiraLax). |
| Kurara Masikati | Mishonga yakaita seModafinil (yakadai seProvigil). |
| Kuora Mwoyo kana Kunetseka | Mishonga yekudzora kushungurudzika yerudzi rweSSRI. |
| Kufungidzira/Kufungidzira Zvisizvo | Mishonga chaiyo yekurwisa pfungwa yakaita sepimavanserin. |
| Kusashanda zvakanaka kweSimba reKubereka | Mushonga weSildenafil (wakafanana neViagra). |
Chii chimwe chingaitwe kunze kwemishonga?
Mishonga ingori chikamu chimwe chete chehondo iyi. Pamusoro pezvo, kune zvimwe zvinhu zvakawanda zvinogona kuvandudza hupenyu hwemurwere.
Kurovedza muviri nekurovedza muviri zvakakosha zvikuru mukurapa chirwere cheParkinson. Kutaura zvazviri, kurovedza muviri ndicho chinhu chega chakaratidzwa kuti chinononotsa kufambira mberi kwechirwere.
- Kurapa kwemuviri: Zvirongwa zvekurapa kwemuviri zvakagadzirirwa varwere veParkinson zvinogona kuvandudza kuenzana, kufamba, uye kugadzikana.
- Kurovedza muviri: Zvakakosha zvikuru kuita kurovedza muviri kwemwoyo kwemaminitsi angangoita 150 pasvondo. Mabasa akadai sekuchovha bhasikoro nebhokisi akaonekwa kuti anobatsira zvikuru.
- Hutano Hwepfungwa: Kurarama nechirwere chisingaperi seParkinson kunogona kunetsa pfungwa. Saka kana uchisuruvara kana kunetseka, usazeza kutaura nenyanzvi yehutano hwepfungwa, senge chiremba wepfungwa.
Ndinofanira kuona chiremba zvakare rini?
Paunenge uchitora mushonga weParkinson, zvakakosha kuti ugare uchiona chiremba wako kuti uone kana mushonga wacho uchishanda uye kana uine zviratidzo zvitsva. Iva nechokwadi chekutaura nachiremba wako, kunyanya mumamiriro ezvinhu akadai.
- Kana ukasangana nemigumisiro yausingakwanise kutsungirira.
- Kana zviratidzo zvako zvikasavandudzika kana kuti zvikasawedzera kuipa.
- Kana uchinzwa kuda kurega mushonga.
Mharidzo Yekuenda Nayo Kumba
- Kunyange hazvo chirwere cheParkinson chisingarapike zvachose, zviratidzo zvacho zvinogona kudzorwa zvakanaka uye unogona kurarama hupenyu hwakanaka.
- Levodopa ndiyo mushonga mukuru uye unoshanda zvakanyanya pakurapa chirwere ichi.
- Usarega kutora mishonga kana kuchinja mwero wemushonga chero chikonzero chipi zvacho usina kurairwa nachiremba wako.
- Kurovedza muviri nekurovedza muviri zvakakosha sekushandisa mishonga. Kurovedza muviri kunogona kubatsira kudzora kuenderera mberi kwechirwere.
- Kana ukasangana nemigumisiro kana mamwe matambudziko, usatya kutaura nachiremba wako. Iye anogara akagadzirira kukubatsira.
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