Unowanzo nzwa kuneta here, kunetseka nedambudziko rekugaya chikafu nguva dzose, kana kuti unonzwa manyoka asina kutsanangurwa? Uri kuona shanduko dzisingawanzoitika paganda here kana kuti uri kunetseka nekutadza kuyeuka? Kunyange zvazvo zviratidzo izvi zvichigona kusanganiswa nemamiriro akasiyana-siyana, zvinogona kureva chimwe chinhu chinowanzo tariswa nezvehutano. Nhasi, tiri kutaura nezvechirwere chinozivikanwa sePellagra .
Chii chinonzi Pellagra?
Zvichitaurwa zviri nyore, Pellagra chirwere chinokonzerwa nekusadya Niacin yakakwana, inozivikanwawo seVitamin B3 . Ichi chirwere chinokonzerwa nekushaya kudya kwakakwana—kunyanya kushomeka kwezvinovaka muviri. Muviri wako unoda Niacin kuti masero ashande zvakanaka. Kana huwandu hwemasero hwadzikira, kukanganisa uku kunonzwa mumuviri wako wese, kunyanya paganda, muromo, kugaya chikafu, uye uropi. Pasina kupindira kwakakodzera kwechiremba, Pellagra inogona kukonzera kukuvara kwetsinga zvachose uye, muzviitiko zvakakomba, inogona kuuraya.
Ungashamisika kana izvi zvichikanganisa munhu wese. Kazhinji, avo vanodya chikafu chakakwana vanowana Niacin yakakwana. Primary Pellagra—inokonzerwa nekushaikwa kwekudya—inonyanya kuonekwa munzvimbo dzisina chikafu chakawanda. Zvisinei, munzvimbo dzakabudirira, kusanganisira Sri Lanka, kushomeka kweNiacin kunowanzokonzerwa nezvikonzero zvechipiri. Izvi zvinoreva kuti mamwe matambudziko ehutano kana zvinhu zviri kudzivirira muviri wako kunwa kana kushandisa Niacin yaunodya.
Chii chinonzi Niacin, uye nei uchichida?
Funga nezveNiacin sechinhu chinowedzera mafuta chinoita kuti "injini" yemuviri wako ishande zvakanaka. Kungofanana neinjini inoda mafuta akagadziriswa kuti ishande, muviri wako unoda Niacin kuti igadzire macalorie aunodya kuita simba rinoshanda.
Kana yangopinda muura hwako hudiki, Niacin inoshandurwa kuita coenzyme inokosha inonzi Nicotinamide Adenine Dinucleotide (NAD) . NAD inotsigira ma enzymes anopfuura 400 mumuviri wako. Zvichitaurwa zviri nyore, NAD inokosha pakugadzira simba remasero rinozivikanwa seAdenosine Triphosphate (ATP) . Kunze kwekugadzirwa kwesimba, NAD inokosha pakugadzirisa DNA nekutaurirana kwemasero.
Kushomeka kweNiacin kunokanganisa sei muviri wako?
Nekuti NAD inokosha pakusimbisa masero, kushomeka kunokanganisa masisitimu ane simba rakawanda kana kushanduka kwemasero nekukurumidza: ganda rako, jira remudumbu mako, uye uropi hwako. Vanachiremba vanowanzo tsanangura zviratidzo zvikuru zvePellagra se "3 Ds": Manyoka, Dermatitis, uye Dementia. Vamwe vanowedzera "D" yechina: Rufu . Kana ikasarapwa kwenguva yakareba, mhedzisiro yacho inogona kuuraya.
1. Manyoka (Matumbu emudumbu)
Manyoka anoitika kana jira rekudzivirira riri mudumbu rako rikatadza kupora zvakanaka. Pasina chidziviriro ichi, ura hwako hunonetseka kugaya chikafu uye hunozvidzivirira kubva kuhutachiona nekukuvara. Izvi zvinotungamira kuzvimba kusingaperi mudumbu rese, zvichiratidza kurwadziwa mudumbu, kusagadzikana kwekugaya, maronda mumuromo, uye rurimi rutsvuku rwakazvimba.
2. Dermatitis (Kunzwa kweganda)
Pellagra inokonzera chirwere cheganda chakasiyana, kunyanya munzvimbo dzinosangana nezuva dzakadai sekumeso , mutsipa, maoko, netsoka. Pasina simba rakakwana remasero, masero eganda anonzwa zvakanyanya kuvhenekwa nechiedza cheUV. Pakutanga, ganda rinogona kutaridzika sedzvuku uye rakapiswa nezuva, pakupedzisira richiva rakaomarara, rine makwapa, uye rinotanga mavanga ane pigment (mavara akasviba) . Chiratidzo chinoratidza bhandi gobvu, rakasviba rakatenderedza mutsipa rinozivikanwa se "Casal's collar," rakatumidzwa zita rachiremba Don Gaspar Casal, uyo akatanga kuziva chirwere ichi muna 1735.
3. Dementia (Kukuvadzwa kwehuropi netsinga)
Nekuti Pellagra inokanganisa kugadzirwa kwesimba musero rega rega, inopedzisira yakanganisa uropi nehurongwa hwetsinga. Zviratidzo zvekutanga zvinogona kunge zvisingaonekwe, zvakaita sekuneta kunogara kwenguva refu, kushaya hanya (kushaya hanya), kana kuoma kuisa pfungwa pachinhu chimwe chete. Unogonawo kunetseka kana kuora mwoyo.Nekufamba kwenguva, zviratidzo izvi zvinogona kuwedzera kuita kuvhiringidzika uye kufungidzira. Muzviitiko zvakakomba, chirwere chepfungwa chisingaperi chinogona kuitika, pamwe chete nekutadza kushanda zvakanaka kwepfungwa dzakadai sekusagadzikana , kusafamba zvakanaka, kugwinha kwetsandanyama, uye kudedera.
Pellagra inonyanya kuwanikwa kupi?
Munhoroondo, Pellagra yaiwanikwa nevanhu vakanga vasina kudya kwakakwana, kunyanya avo vainyanya kushandisa chibage (chibage) sechikafu chikuru vasina kuwana zvekudya zvinovaka muviri zvine mapuroteni akawanda. Kunyangwe chibage chine Niacin, chiripo muchimiro "chakabatana" icho muviri wemunhu usingakwanise kunwisa zviri nyore.
MuCentral neSouth America, nzira dzechinyakare dzekugadzira chibage kuita matortilla dzinosanganisira kunyikwa zviyo mumvura yeraimu. Maitiro aya anoburitsa Niacin yakasungwa, zvichiita kuti iwanikwe nyore nyore. Nekuda kweizvozvo, Pellagra ( Pellagra ) haiwanzoonekwa munzvimbo idzodzo.
Nhasi uno, kuwedzera simba rekudya zvakadai sehupfu nemupunga kwakaderedza zvakanyanya Pellagra yekutanga munzvimbo zhinji dzepasi. Zvisinei, kunyange zvisingawanzoitiki, tinofanira kuramba takangwarira nezvezvimwe zvikonzero zvePellagra. Kana uchifungidzira kuti une zviratidzo izvi, taura nechipatara chiri pedyo newe kana masevhisi ekukurumidzira nekukasika.
Ndezvipi zviratidzo zvePellagra?
Heano zviratidzo zvinowanzoonekwa nePellagra:
- Manyoka anogara achibuda ropa , ayo dzimwe nguva anogona kuva neropa.
- Kurwadziwa kwemudumbu uye kusagadzikana kwekugaya chikafu .
- Kushaya chido chekudya , kuda kurutsa , uye kurutsa .
- Ganda rinokwenya kana mapundu eganda anorwadza.
- Maronda emuromo uye rurimi rutsvuku rwakazvimba.
- Kuneta kwakanyanya, kushaya simba, uye kunzwa kusagadzikana kwepfungwa.
- Kuchinja kwemanzwiro uye kuora mwoyo.
- Zviratidzo zvetsinga - semuenzaniso, kudedera mumakumbo kana kuti kusanzwa.
- Kuvhiringidzika kwepfungwa uye zviratidzo zvekushaya pfungwa.
Ndezvipi zvikonzero zvePellagra?
Chikonzero chikuru kudya kusina niacin yakakwana (Vitamin B3). Kunyange zvazvo tichiwana niacin kubva muzvikafu zvakasiyana-siyana, vanhu vasina mukana wakakwana wekuwana kudya kwakakwana vanogona kushaya.
Pamusoro pezvo, unogona kutanga chirwere chepellagra nekuda kwezvikonzero zvechipiri . Izvi zvinoreva kuti muviri wako haugone kupinza kana kushandisa niacin zvakanaka nekuda kwechimwe chirwere. Mienzaniso inosanganisira:
- Zvirwere zvemudumbu zvinokonzera kusamwisa zvakanaka - zvakaita seInflammatory Bowel Disease (IBD) kana kuti liver cirrhosis.
- Dambudziko rekushandisa doro: Kunwa doro zvakanyanya kunokuvadza nhengo dzemuviri dzakadai sechiropa, zvichikanganisa kunwa kwezvinovaka muviri zvakakosha senge niacin uye zvichikonzera kushaya chikafu chakakwana.
- Kuvhiyiwa kwemudumbu: Mushure mekuvhiyiwa, kukuvara kwemukati medumbu kunogona kukanganisa kunyudzwa kwezvinovaka muviri zvakakosha, kusanganisira niacin.
- Kushaya iron anemia: Muviri wako unoda iron kuti ugone kushandura nekushandisa niacin zvinobudirira.
- Chirwere cheHartnup: Chirwere chemajini apo muviri unotadza kupinza mamwe maamino acid anodiwa pakugadzira mavhitamini.
- Carcinoid syndrome: chirwere checarcinoid:Mamwe masero egomarara anogona kuderedza kugadzirwa kwe niacin mumuviri.
- Mimwe mishonga: Kunyanya mimwe mishonga inorwisa kurwadza kwemusoro uye mishonga yechemotherapy inogona kukanganisa metabolism ye niacin.
- Kutapukirwa neHIV: HIV inogona kukonzera kudzikira kwehuwandu hwe niacin mumuviri.
Pellagra inoonekwa sei?
Paunoshanyira chiremba, vanokuongorora, voongorora zviratidzo zvako, nhoroondo yezvekurapa, uye maitiro ekudya. Kana chiremba wako achifungidzira kuti une chirwere chepellagra, vanogona kuraira kuti uedze weti kuti vaone kana muviri wako uri kuwana niacin yakakwana. Chiremba wako anogonawo kunyora mishonga yekuwedzera niacin kuti aone kana zviratidzo zvako zviri nani; iyi yekurapa ndiyo imwe nzira inoshandiswa pakuongorora chirwere ichi kuNirogi Lanka nedzimwe nzvimbo dzekiriniki.
Ndezvipi zvirongwa zvekurapa Pellagra?
Sezvo pellagra ichikonzerwa nekushaikwa kwe niacin (Vitamin B3), mushonga unoshanda zvikuru ndewekudzosera chikafu chisipo kuburikidza ne niacin supplements. Vanhu vazhinji vanotanga kunzwa zviri nani nekukurumidza kana kurapwa kwatanga. Zvisinei, ungangoda kutarisirwa kwakawedzerwa kwezviratidzo zvechipiri zvakaita semaronda eganda kana emuromo.
Chinonyanya kukosha ndechekuti, kana chirwere chako chepellagra chikakonzerwa nechimwe chirwere chechipiri, unofanira kurapwa zvakakodzera nekuda kwedambudziko iroro rehutano.
Pane migumisiro yakaipa pakurapa here?
Kana ikatorwa sezvakarairwa nachiremba wako, mishonga yekuwedzera ye niacin haiwanzo kukonzera migumisiro yakaipa. Migumisiro yakaipa inowanzoitika chete kana munhu akashandisa zvinodhaka zvakanyanya, izvo zvisingawanzoitiki kune munhu ane chirwere chekushaya simba. Kana zvikaitika, zvinogona kusanganisira:
- Kusviba kweganda.
- Kukwenya kana mapundu.
- Kuzvimba uye kusagadzikana kwekugaya chikafu.
- Musoro nedzungu.
Ungadzivirira sei chirwere chePellagra?
Kudya zvine mwero ndiyo nzira iri nyore yekuona kuti une chikafu chakakwana. Kana uine chikafu chisina kukwana, chikafu chakapfuma uye zvekudya zvinovaka muviri zvinogona kubatsira. Munhu mukuru ane hutano anowanzoda 15mg ye niacin zuva rega rega, iyo inowanzopihwa neB-complex vitamin supplement.
Zvikafu zvakapfuma mu niacin zvinosanganisira:
- Chiropa chemombe
- Mabheti
- Mbiriso yemubiki
- Chingwa chakapfumiswa nezviyo
- Hove dzine mafuta, dzakadai sesalmon netuna
- Nzungu
- Mbatatisi
- Huku
- Mupunga
- Mbeu dzezuva
- Muto wespaghetti
Kana uine chirwere chisingaperi chinowedzera njodzi yako yekubata chirwere chepellagra, taura nachiremba wako nezvenzira yekudzivirira kwenguva refu, iyo inogona kusanganisira kugadzirisa kudya kwako, mishonga yekuwedzera, kana mishonga yauri kushandisa pari zvino.
Zvinotora nguva yakareba sei kuti munhu apore kubva kuPellagra?
Kana wangotanga kutora mishonga yekuwedzera niacin, vanhu vazhinji vanoona kuvandudzika mukati memazuva mashoma. Zviratidzo zvemudumbu (semanyoka) zvinowanzotanga kupera , kazhinji mukati mevhiki yekutanga. Maronda eganda nemuromo anogona kutora kusvika mavhiki maviri kuti apore. Nyaya dzakakomba dzinogona kutora nguva yakareba. Ndokumbirawo mucherechedze: kukuvara kwakanyanya kwetsinga uye dementia dzimwe nguva hazvigoneke.
Vanachiremba vanokurudzira kuchengetedza kudya kwakaringana kudzivirira chirwere chekutanga chepellagra mune ramangwana. Kushomeka kweNiacin kunowanzoenderana nekushaikwa kwezvimwe zvinovaka muviri, zvese izvi zvinogona kugadziriswa nekudya zvine hutano.
Kurapa chirwere chepiri chepellagra kwakaoma zvikuru. Kunyange zvazvo mishonga yekuwedzera ichibatsira, inogona kusakwana kana muviri wako usingakwanise kushandisa niacin nemazvo. Muzviitiko izvi, kupora kunoenderana nekuziva nekurapa chirwere chiripo, izvo zvinogona kutora nguva refu.
Mharidzo Yekupedzisira Yekuenda Kumba
Kunyange hazvo chirwere cheprimary pellagra chichinyanya kupedzwa munzvimbo dzakabudirira, chinoramba chiri njodzi kuvanhu vasina chikafu chakawanda. Munharaunda medu, kushomeka kwe secondary niacin kuchiri kunetseka nekuda kwekushandisa doro zvisina kunaka uye matambudziko ehutano—kunyanya ayo anokanganisa kunwa kwezvinovaka muviri. Kana uchifungidzira kuti une zviratidzo izvi, tsvaga rubatsiro kubva kuna chiremba kuchipatara chemunharaunda yako nekukasika.
Chinhu chakakosha kurangarira ndechekuti kunyangwe kudya kunovaka muviri kuchitanga nechikafu chaunodya, maitiro emuviri wako ndiwo anonyatsosarudza hutano hwako. Muviri wako unovimba nemabasa akaomarara emukati kuti urambe uine hutano. Kana ukaona zviratidzo zvinokunetsa—kunyanya matambudziko ane chekuita nekugaya kwako— ndapota tsvaga mazano echiremba ane hunyanzvi. Kunyangwe kushomeka kwemavhitamini kudiki kunogona kukanganisa hutano hwako zvakanyanya. Saka, tarisa pakudya chikafu chakaringana, chengetedza mararamiro ane hutano, uye bvunza chiremba nekukurumidza kana uine chero matambudziko ehutano.
Pellagra, Niacin, Vhitamini B3, Kushaikwa Kwekudya, Matambudziko Eganda, Manyoka, Dementia
