Yintoni iGlycogen? Masithethe ngendlela umzimba wethu ogcina ngayo amandla ngendlela elula!

Ngaba wakha wazibuza ukuba imizimba yethu iwagcina njani amandla esiwafumana ekutyeni esikutyayo ukuze siwasebenzise kamva? Kulapho ke into ekhethekileyo ebizwa ngokuba yi-glycogen ingena khona. Ifana nebhanki yamandla egcina iifowuni zethu zitshajiwe.

Yintoni i-glycogen?

Ngamafutshane, i-glycogen luhlobo lweswekile ebizwa ngokuba yi-glucose egcinwa emizimbeni yethu. Yenziwe ziimolekyuli ezininzi zeglucose ezidityanisiweyo.

Ngoku usenokuba uzibuza ukuba yintoni i-glucose. I-glucose yeyona fuel iphambili enika amandla emizimbeni yethu. Siyifumana le glucose kwezinye zokutya esikutyayo, ingakumbi ezo ziqulethe ii-carbohydrate. Ukuba i-glucose ekutyeni esikutyayo ayifuneki ngoko nangoko ukuze ibe namandla, imizimba yethu iyigcina njenge-glycogen esibindini nakwimisipha , ukuze isetyenziswe kamva.

Inkqubo eyenziwa ngumzimba wethu ukwenza i-glycogen kwi-glucose ibizwa ngokuba yi -Glycogenesis . Kwakhona, inkqubo eguqulwa ngayo le glycogen ibe yi-glucose xa ifuneka kwaye isetyenziselwa amandla ibizwa ngokuba yi-Glycogenolysis . Zombini ezi nkqubo zincediswa ziintlobo ezahlukeneyo zee -enzyme . Ii-enzyme ziintlobo ezikhethekileyo zeeproteni ezifumaneka ngaphakathi kwiiseli zethu. Zisebenza njengee-catalysts kwaye zinceda iinkqubo ezahlukeneyo emzimbeni ukuba zisebenze kakuhle. Kukho amawaka ee-enzyme ezinjalo emzimbeni wethu, kwaye nganye yazo yenza umsebenzi obalulekileyo.

Yintoni umahluko phakathi kweGlycogen, iGlucose kunye neGlucagon?

Ngoku masibone ukuba yintoni umahluko phakathi kwala magama mathathu: iGlycogen, iGlucose, kunye neGlucagon. Onke la magama mathathu anxulumene nendlela imizimba yethu esebenzisa ngayo iicarbohydrates ukuze ifumane amandla, kodwa ngalinye linomsebenzi owahlukileyo.

IswekileLuhlobo lweswekile esilufumana ekutyeni esikutyayo, ingakumbi iicarbohydrates. Uhlobo oluphambili lweswekile egazini lethu yiglucose egazini, okanye oko sikubiza ngokuba ' yiswekile egazini'. Le swekile inika imizimba yethu amandla, kwaye ikwayondla amalungu ethu omzimba, izihlunu, kunye nenkqubo yemithambo-luvo. Iswekile ibaluleke kakhulu kuba ngumthombo ophambili wamandla kwingqondo yethu. Enyanisweni, ingqondo yethu ihlala ifuna iswekile, yiyo loo nto kucetyiswa ukuba umntu omdala atye ubuncinci iigram ezili-130 zeecarbohydrates ngosuku.

Ngoku siyazi ukuba xa imizimba yethu ingasafuni glucose ngequbuliso, igcinwa kwisibindi nakwimisipha yethu njenge -glycogen .

I-Glucagon yi-hormone eveliswa yi-pancreas yethu. Inceda ukuguqula i-glycogen egciniweyo ibuyele kwi-glucose kwaye iyikhuphe egazini. Umzimba ungayisebenzisa loo glucose ukuze ufumane amandla. I-Glucagon kunye ne -insulin zii-hormone ezimbini ezilawula ikakhulu amanqanaba e-glucose egazini emzimbeni wethu.

Ngaba i-glycogen yi-carbohydrate?

Ngoko ke, ngaba i-glycogen yi-carbohydrate? Kaloku, i-glycogen yenziwe ngee-carbohydrate, oko kukuthi, kukutya okunesitatshi esikutyayo. Nangona kunjalo, i-glycogen ayisiyo-carbohydrate ngokwayo. Xa sitya ukutya okunee-carbohydrate, imizimba yethu iyawaphula ize iwaguqule abe yi-glucose ukuze isetyenziselwe amandla. I-Glycogen yindlela egcinwa ngayo i-glucose. Yenziwe ziimolekyuli zeglucose ezidityaniswe kunye.

Igcinwa phi i-glycogen?

Kulungile, ke ngoko le glycogen igcinwa phi emizimbeni yethu? I-Glycogen igcinwa ikakhulu emizimbeni yethu.Ifumaneka kwimisipha yesibindi kunye neyamathambo . Imisipha yimisipha enamathele emathanjeni nakwimisipha yethu. Ukongeza, inani elincinci kakhulu ligcinwa engqondweni yethu.

Nangona isibindi sethu sigcina ipesenti ephezulu ye-glycogen kunemisipha yethu, ubunzima bemisipha yethu iyonke bukhulu kakhulu kunesibindi sethu, ngoko ke yikota yesithathu kuphela ye-glycogen iyonke emzimbeni ekwimisipha yethu.

Xa sizilolonga ngamandla, ingakumbi ixesha elide, ubungakanani be-glycogen kwiiseli zemisipha ezisebenzayo bunokwehla kakhulu. Ubungakanani be-glycogen kwiiseli zesibindi buyatshintsha imini yonke. Oku kungenxa yezizathu ezahlukeneyo:

• Ubungakanani beecarbohydrate esizityayo.
• Ixesha esiligcinayo phakathi kokutya.
• Ubungakanani kunye nobude bomsebenzi womzimba esiwenze kutshanje.

Khawucinge nje, ukuba awutyi iiyure ezili-12 ukuya kwezingama-24 (uzila ukutya), phantse yonke i-glycogen esibindini iphelile.

I-glycogen inceda njani emizimbeni yethu?

Ngoku makhe sibone ukuba le glycogen inceda entwenini emzimbeni wethu. Ngokuxhomekeke ekubeni igcinwe phi – nokuba isesibindini okanye kwimisipha – umsebenzi wayo uyahluka kancinci.

Umsebenzi weeVenkile zeGlycogen zeSibindi

Imizimba yethu isebenzisa i-glycogen, ikakhulu esibindini , ukunceda ukulawula amanqanaba eglucose egazini lethu.

Ngokwesiqhelo, imizimba yethu ilawula ngononophelo amanqanaba eswekile egazini lethu ngeehomoni ezibizwa ngokuba yi-glucagon kunye ne-insulin. Ukuba amanqanaba eswekile egazini lethu aphantsi kakhulu, okubizwa ngokuba yi-hypoglycemia , i-pancreas yethu ikhupha i-glucagon engaphezulu. Enye yezinto ezenziwa yi-glucagon kukuguqula i-glycogen esibindini ibuyele kwi-glucose kwaye iyikhuphe egazini. Ungakhumbula ukuba sayibiza le nkqubo ngokuba yi-glycogenolysis. Xa i-glucose ikhutshwa egazini, iiseli emzimbeni wonke zingayisebenzisa njengombane.

IiGlycogen ezigcinwe esibindini zikwanceda ekusebenzeni kwezihlunu kunye nokuzilolonga ukuya kuthi ga kwinqanaba elithile. Kwangoko nje xa uqala ukuzilolonga, izihlunu zakho ezisebenzayo zisebenzisa iglucose ukuze zifumane amandla, ngoko ke isibindi siqala ukuqhekeza iglycogen ukuze kugcinwe amanqanaba eswekile egazini. Nangona kunjalo, izihlunu zakho zisebenzisa ikakhulu ii-glycogen zazo.

Umsebenzi weeVenkile zeGlycogen zeMiscle

I-Glycogen kwimisipha isebenza njengomthombo wamandla e-metabolic kwimisipha yethu.

Ukuze sishukume, izihlunu zethu zifuna amandla amaninzi. Khawucinge nje, ukuba izihlunu zethu bezingathatha iglucose egazini ukuze zifumane la mandla, iglucose emzimbeni ibiya kuphela ngokukhawuleza.

Yiyo loo nto imizimba yethu igcina i-glycogen ezi-3 kwisine kwimisipha nganye yamathambo. Oku kuvumela imisipha ukuba iqhubeke nokufumana amandla ngaphandle kokuchaphazela kakhulu amanqanaba eswekile egazini, ingakumbi ngexesha lokuzilolonga.

Izinga lokuphelelwa yi-glycogen kwimisipha yethu lixhomekeke kakhulu kubunzima bomsebenzi womzimba. Njengoko amandla omthambo esanda, izinga lokuphelelwa yi-glycogen kwimisipha nalo liyakhula. Ke ngoko, ngexesha lemisebenzi enamandla kakhulu, njengokubaleka ngokukhawuleza , ii-glycogen ezigcinwa kwiiseli zemisipha ezisebenzayo zinokuphelelwa ngokukhawuleza, nokuba ixesha elipheleleyo lomsebenzi lifutshane.

Xa sitya iicarbohydrate ezaneleyo, izihlunu zethu zizaliswa yi-glycogen kwakhona.

Yintoni iGlycogen Storage Disease (GSD)?

Ngamanye amaxesha, iingxaki zinokuvela ngale glycogen. Enye yezi meko sisifo sokugcina iglycogen, okanye i-GSD ngamafutshane .

I-GSD yimeko engaqhelekanga, ezuzwe njengelifa.Oku kwenzeka xa umntu ezalwa engenazo ii-enzyme ezithile ezifunekayo ukwenza kunye/okanye ukuqhekeza i-glycogen. Ngenxa yokuba imizimba yethu isebenzisa ii-enzymes ezininzi ezahlukeneyo ukucubungula i-glycogen, kukho iintlobo ezininzi ezahlukeneyo ze-GSD. I-GSD inokubangela umonakalo wesibindi kunye nobuthathaka bemisipha . Kwiintlobo ezininzi ze-GSD, iimpawu ziqala ukubonakala ebuntwaneni okanye ebuntwaneni.

Ziziphi iimvavanyo ezikhoyo zokujonga amanqanaba e-glycogen?

Ngoko ke, ngaba kukho naziphi na iimvavanyo ezikhethekileyo zokujonga amanqanaba e-glycogen emzimbeni wethu? Enyanisweni, akukho vavanyo lukhethekileyo olulinganisa amanqanaba e-glycogen kuphela. Ngaphezu koko, amanqanaba ethu e-glycogen atshintsha rhoqo ngokuxhomekeke kubungakanani bomsebenzi esiwenzayo kunye nobungakanani bee-carbohydrate esizityayo ngosuku.

Kunoko, ukuba uneempawu, oogqirha basebenzisa ezinye iimvavanyo ukuze babone ukuba unengxaki na ngendlela umzimba wakho ovelisa kwaye udiliza ngayo i-glycogen, ebizwa ngokuba sisifo sokugcina i-glycogen (GSD). Ezi vavanyo zezi:

• Uvavanyo lwegazi: Izinto ezifana nephaneli yokusebenza kwesibindi kunye nephaneli yokusebenza kwezintso zinokukunceda ubone ukuba la malungu asebenza kakuhle kangakanani na. Uvavanyo lwenqanaba leswekile egazini lunokukunceda ubone ukuba umzimba wakho usebenzisa i-glycogen kakuhle kangakanani na. Abantu abane-GSD badla ngokuba neswekile ephantsi egazini.
• I-ultrasound yesisu: Olu vavanyo lomfanekiso lunokunceda ugqirha wakho abone ukuba isibindi sakho sikhulu na.
• I-biopsy yezicubu: Ugqirha wakho unokuthatha isampuli encinci yezicubu kwimisipha okanye kwisibindi sakho aze alinganise amanqanaba e-glycogen okanye ii-enzymes ezikuso.
• Uvavanyo lwemfuza: Ugqirha wakho unokucebisa novavanyo lwemfuza ukuze abone ukuba unayo na imfuza yesifo sokugcina iGlycogen.

Yintoni eyona nto ibalulekileyo ekufuneka siyikhumbule kweli nqaku?

Kulungile, ngoku mhlawumbi uyaqonda ukuba i-glycogen ibalulekile ekulawuleni amanqanaba eswekile egazini lethu kunye nokubonelela ngamandla okwenza umthambo. Ngethamsanqa, iingxaki ngokuveliswa nokusetyenziswa kwe-glycogen emizimbeni yethu zinqabile kakhulu.

Eyona nto ingcono onokuyenza ukuze ufikelele kumanqanaba akho e-glycogen, ingakumbi ukuba ungumdlali wezemidlalo, kukutya iicarbohydrate ezaneleyo yonke imihla. Ukuba unemibuzo malunga nokutya kwakho kunye neenjongo zakho zokuzilolonga, qiniseka ukuba uthetha nogqirha wakho okanye ingcali yokutya ebhalisiweyo. Banokukunika iingcebiso ezifanelekileyo kuwe.