Kuqhelekile ukuba uzive usoyika kwaye unexhala xa wena okanye umntu omthandayo niza kuqala unyango lwe-chemotherapy. Kodwa ukuba nolwazi olupheleleyo malunga nonyango kunye namayeza yeyona ndlela ilungileyo yokoyisa olo loyiko. Namhlanje sithetha ngelinye lamayeza akhethekileyo e-chemotherapy, i-Busulfan. Eli liyeza elihlala linikwa ukulungiselela izigulana unyango olukhulu, njengokufakelwa kweeseli ze-stem, ngakumbi kwizigulana ezine-leukemia ezifana ne-Chronic Myelogenous Leukemia (CML).

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Kalula nje, yintoni iBusulfan?

I-Busulfan liyeza elinamandla kakhulu le-chemotherapy. Umsebenzi walo ophambili kukutshabalalisa iiseli zomhlaza. Ingakumbi ngaphambi kokufakelwa umongo wethambo, eli yeza lisusa iiseli zomongo wethambo ezinesifo okanye ezinomhlaza emzimbeni kwaye lenze indawo yokuba kufakwe iiseli ezintsha eziphilileyo.

Eli yeza alilophilisi onokulithatha ekhaya. Liyeza elinikwa ngemithambo yegazi, njenge-saline (i-infusion). Kwaye linikwa esibhedlele okanye eklinikhi kuphela ngabasebenzi bezonyango abaqeqeshwe ngokukodwa. Ngoko khumbula ukuba usezandleni ezikhuselekileyo.

Izinto ekufuneka uzixelele ugqirha wakho ngaphambi kokuba uqale unyango

Ngaphambi kokuba uqale unyango lweBusulfan, kubaluleke kakhulu ukunika ugqirha wakho umfanekiso opheleleyo wempilo yakho. Olu lwazi luya kunceda ekumiseleni unyango olungcono nolukhuselekileyo kuwe. Ukuba kukho naluphi na kwezi zilandelayo olusebenzayo kuwe, qiniseka ukuba uxelele ugqirha wakho.

Imeko ekufuneka uyixele	Inkcazo
Ukukhulelwa okanye ukuncancisa	Qiniseka ukuba uxelela ugqirha wakho ukuba ukhulelwe, uzama ukukhulelwa, okanye ukrokrela ukuba ukhulelwe. Kwakhona, xelela ugqirha wakho ukuba uncancisa.
Ii-aleji	Sixelele ukuba unayo nayiphi na i-allergies kwiBusulfan okanye naliphi na elinye iyeza le-chemotherapy, naliphi na elinye iyeza, ukutya, okanye idayi.
Ukwenzakala entloko okanye ukuxhuzula	Ukuba ukhe wenzakala kakhulu entloko okanye unembali yokuxhuzula.
Iintsholongwane ezikhoyo	Ukuba okwangoku unentsholongwane (ingakumbi izifo ezibangelwa yintsholongwane ezifana ne-chickenpox okanye i-herpes).
Izifo zesibindi okanye zemiphunga	Ukuba unesifo sesibindi, imiphunga okanye izifo zokuphefumla ezifana ne-asthma.
Iingxaki zegazi	Ukuba unenani eliphantsi leeseli ezibomvu zegazi, iiseli ezimhlophe zegazi, okanye iiplatelets egazini lakho, okanye ukuba unemeko efana ne-thalassemia.
Unyango ngemitha	Ukuba usandul’ ukufumana okanye okwangoku ufumana unyango lwe-radiation.

Izinto ekufuneka uzilumkele ngakumbi ngexesha lonyango

Umzimba wakho usenokuziphatha ngendlela eyahlukileyo xa usebenzisa la mayeza, kwaye kubalulekile ukukwazi oko.

Lumka kakhulu malunga nosulelo.

I-Busulfan inokunciphisa inani leeseli ezimhlophe zegazi emzimbeni wakho ezilwa nezifo. Oku kuthetha ukuba unokufumana usulelo ngokulula.

Zigcine kude nabantu abaneempawu ezifana nomkhuhlane, umkhuhlane, iintlungu zomzimba, kunye nomphimbo obuhlungu kangangoko unako.
Ukuba uziva ngathi uphethwe ngumkhuhlane, kukugodola, ukukhohlela, okanye umphimbo obuhlungu, musa ukuzinyanga kwaye yazisa ugqirha wakho okanye isibhedlele apho unyangwa khona ngoko nangoko.

Lumka ukopha kunye nokudumba.

Eli yeza linokunciphisa inani leeplatelets ezinceda ekuqhekekeni kwegazi. Ke ngoko,

Jonga ukuba uziva unamanxeba lula na kunesiqhelo.
Nika ingqalelo kwiintsini eziphuma igazi, ukopha kwempumlo, igazi elisemchameni, kunye nendle emnyama.
Ukuba ubona into efana nale, xelela ugqirha wakho ngoko nangoko.

Ukukhulelwa kunye nokuchuma

Le yinto ebaluleke kakhulu. Nceda unikele ingqalelo ekhethekileyo kule nto.

Kwabasetyhini: Kubalulekile ukuba bangakhulelwa ngokupheleleyo ngelixa bethatha eli yeza kwaye emva kweenyanga ezi-6 emva kokuyeka unyango. Kukho umngcipheko omkhulu wokwenzakalisa umntwana ongakazalwa.
Kumadoda: Ufanele ukuphephe ukuba nguyise womntwana ngelixa usela eli yeza kwaye kangangeenyanga ezi-3 emva kokuyeka unyango.

Musa ukuncancisa umntwana wakho ngelixa usebenzisa eli yeza nangasiphi na isizathu. Kwakhona, olu nyango lunokuba nefuthe kwindlela onokuba nabantwana ngayo kwixesha elizayo. Ukuba uneenkxalabo okanye uloyiko malunga noku, thetha nogqirha wakho ngalo mba ngokucacileyo.

Zithini iziphumo ebezingalindelekanga ezinokubakho zeyeza?

Njengalo naliphi na iyeza elinamandla, iBusulfan inokuba nemiphumo emibi. Ezinye zezi zinto kufuneka zixelwe ngoko nangoko, ngelixa ezinye zingabi yingozi kangako. Masizichaze.

Iziphumo ebezingalindelekanga ekufuneka zixelwe kugqirha wakho ngoko nangoko
Ukusabela kwi-Allergic	Ukurhawuzelela kwesikhumba, ukurhawuzelela, ukudumba kobuso, imilebe okanye ulwimi.
Ubunzima bokuphefumla	Ubunzima bokuphefumla, iintlungu zesifuba.
Ukuxhuzula	Ukuxhuzula ngequbuliso.
Iimpawu zomonakalo wesibindi	Ukutyheli kwamehlo okanye ulusu, umchamo otyheli/omdaka omnyama, iintlungu kwicala eliphezulu lasekunene lesisu, isicaphucaphu, ukungabi namdla wokutya.
Iimpawu zokubala iiseli zegazi eziphantsi	Iimpawu zosulelo: umkhuhlane, ukubanda, umphimbo obuhlungu. Iimpawu zokopha: ukukrweleka okungaqhelekanga, amabala abomvu phantsi kolusu, indle emnyama. Iimpawu ze-anemia: ukudinwa kakhulu, ukuphaphatheka, ukuquleka.
Intlungu ebuhlungu yesisu okanye ukuhlanza	Intlungu ebuhlungu esiswini okanye ukuhlanza okungenakunqandwa.

Izinto eziqhele ukungabi yingozi, kodwa kufuneka zixelwe kugqirha ukuba ziyaqhubeka
Urhudo	Isisu esibuhlungu
Intloko ebuhlungu	Intloko ebuhlungu ngamanye amaxesha
Ixhala	Ukuziva uxhalabile, ungaphumli
Izilonda zomlomo	Izilonda ezibuhlungu emlonyeni okanye emilebeni
Ukungalali	Ubunzima bokulala ebusuku

Iingxaki ezinokubakho ngamanye amayeza

Amanye amayeza owasebenzisayo asenokusebenzisana neBusulfan. Ngoko ke, onke amayeza owasebenzisayo kufuneka ajongwe ngononophelo.Xelela ugqirha wakho ngamayeza akho. Oku akuthethi nje kuphela amayeza amiselwe ngugqirha wakho, kodwa kunye nawo nawaphi na amayeza okunciphisa iintlungu athengiswa ngaphandle kwemvume kagqirha (umz., i-acetaminophen), iivithamini, amayeza esintu okanye e-Ayurvedic/Sinhala, kunye nezongezo zokutya. Qiniseka ukuba uxelela ugqirha wakho ngawo nawaphi na amayeza alandelayo owasebenzisayo:

I-Acetaminophen (efana nePanadol)
Itraconazole (iyeza lokulwa nentsholongwane)
I-Metronidazole
I-Phenytoin (iyeza lokuxhuzula)
Izitofu eziphila

Malunga nomthamo wamayeza

Ekubeni eli yeza linikwa esibhedlele, ukuba awukwazi ukufumana unyango ngomhla omiselweyo, nceda ufowunele ugqirha wakho ngoko nangoko kwaye umazise. Musa ukuyeka okanye ukutshintsha unyango ngokungacwangciswanga nangasiphi na isizathu. Ukuba ukrokrela ukuba uthatha i-overdose, fowunela iZiko loLwazi lweePoisons kwiSibhedlele sikaZwelonke saseColombo ngoko nangoko, okanye uye kwiYunithi yoNyango oluNgxamisekileyo (ETU) yesibhedlele esikufutshane.

Umyalezo Wokuya Ekhaya

I-Busulfan liyeza elinamandla le-chemotherapy elinikwa ngaphambi kokufakelwa umongo wethambo. Linikwa esibhedlele ngabasebenzi abaqeqeshiweyo.
Qiniseka ukuba uxelela ugqirha wakho ngazo zonke iimeko zakho zempilo kunye nawo onke amayeza owasebenzisayo ngaphambi kokuba unyango luqale.
Ngexesha lonyango, lumka xa ubona iimpawu zosulelo (umkhuhlane, ukukhohlela) kunye neempawu zokopha (ukugruzuka okungaqhelekanga, ilindle elimnyama). Ukuba kukho into oyikrokrelayo, xelela ugqirha wakho ngoko nangoko.
Kubaluleke kakhulu: Abafazi mabaphephe ngokupheleleyo ukukhulelwa abantwana iinyanga ezi-6 emva konyango, namadoda iinyanga ezi-3.
Thetha ngokukhululekileyo nogqirha wakho ngayo nayiphi na imibuzo, uloyiko, okanye iinkxalabo onokuba nazo. Khumbula ukuba awuwedwa.