Sonke siyazi ukuba iiseli ezimhlophe zegazi emizimbeni yethu zifana namajoni asikhusela kwizifo. Kodwa khawucinge, kwenzeka ntoni ukuba ezi seli zikhuselayo, ezibizwa ngokuba zii-histiocytes, zikhula kakhulu emizimbeni yethu? Kulapho ke ingxaki iqala khona. Ezi seli zinokuqokelelana kwaye zenze iithumba kunye nezilonda kwiindawo ezahlukeneyo zomzimba. Namhlanje sithetha ngesifo esingaqhelekanga esikhula ngolu hlobo.
Yintoni i-LCH (i-Langerhans cell histiocytosis)?
Ngamafutshane, i-LCH (i-Langerhans Cell Histiocytosis) yimeko engaqhelekanga efana nezinye iintlobo zomhlaza. Kule meko, uhlobo lweseli yomzimba olubizwa ngokuba yi-Langerhans lukhula ngokungalawulekiyo kwaye luqokelelana kwiindawo ezahlukeneyo zomzimba.
Esi sifo sibonakala kakhulu kubantwana abancinci nakwiintsana , kodwa sinokuvela nakubantu abadala. Nangona ngamanye amaxesha kucingelwa ukuba ngumhlaza, asingomhlaza ngokwenene. Nangona kunjalo, sinyangwa ngoogqirha be-oncology. Ngoko ke ungakhathazeki. Makhe sijonge oku ngakumbi.
Zithini iimpawu zesi sifo?
I-LCH inokuchaphazela naliphi na ilungu lomzimba. Umzekelo, inokuchaphazela imiphunga, isibindi, ingqondo, i-spleen, okanye ii-lymph nodes. Nangona kunjalo, iimpawu eziqhelekileyo zibonakala kulusu nasemathanjeni.
Abanye abantu banokuba neempawu ezibuthathaka kakhulu baze baphile ngokwabo ngaphandle konyango. Nangona kunjalo, kwabanye, inokuba yimeko yexesha elide echaphazela amalungu amaninzi omzimba.
Makhe sijonge le theyibhile ingezantsi ukuze sibone ukuba zeziphi iimpawu ezibonakaliswa yi-LCH xa ichaphazela amalungu ahlukeneyo omzimba.
| Inxalenye yomzimba echaphazelekayo | Iimpawu ezinokubonwa |
|---|---|
| Amathambo | Kudla ngokwenzeka ukudumba okanye amaqhuma abuhlungu (iigranuloma) ekhayeni nakwamanye amathambo. Oku kunokubangela intlungu emathanjeni, ukudumba, kwaye ngamanye amaxesha kwanokuqhekeka kwamalungu omzimba. |
| Ulusu | Amaqhuqhuva abomvu, anamaqhuqhuva kwimiphetho yesikhumba (umz., emakhwapheni, emathunjini). Iintsana zinokuba namaqhuqhuva abomvu, anamaqhuqhuva entlokweni. Oku ngamanye amaxesha kunokuphambaniswa ne-cradle cap, eyimeko eqhelekileyo. |
| Isibindi | Isibindi sidla ngokuchaphazeleka kwiimeko ezinzima zesifo. Iimpawu ziquka ukutyheli kolusu (i-jaundice) kunye nokulibaziseka ekujiyeni kwegazi. |
| Ithumba | Ukudumba kwamadlala emva kweendlebe, entanyeni, nakwezinye iindawo. Ukongeza, ubunzima bokuphefumla nokukhohlela bunokubakho. |
Indlela yokuxilonga ngokuchanekileyo isifo?
Ukuba ugqirha wakho urhanela esi sifo, kuya kufuneka enze i-biopsy ukuqinisekisa ukuba uxilongiwe. Oku kuquka ukuthatha iqhekeza elincinci kakhulu lesicwili kwindawo ekrokrisayo size silihlolwe phantsi kwe-microscope yingcali yezifo. Oku kuya kukhangela iiproteni ezithile kunye nezinye iimpawu ezikhethekileyo zesifo.
Ukongeza, ugqirha wakho unokuyalela uvavanyo olongezelelweyo ngokuxhomekeke kwiimpawu zakho.
- Uvavanyo lwe-X-ray: Jonga imeko yemiphunga namathambo akho.
- I-Bone marrow biopsy: Ukujonga iiseli ze-LCH kwi-bone marrow.
- Uvavanyo lwekhemikhali yegazi: Jonga ukusebenza kwezintso, isibindi, indlala yegilo, kunye nenkqubo yomzimba yokuzikhusela.
- I-MRI, i-PET, kunye ne-CT scans: Fumana imifanekiso eneenkcukacha zangaphakathi lomzimba.
- Uhlalutyo lomchamo: Jonga amanqanaba eeseli ezibomvu nezimhlophe, iiproteni, kunye neswekile kumchamo.
Yintoni ebangela i-LCH?
Asikazi kakuhle ukuba kutheni abanye abantu befumana i-LCH. Kodwa kufunyenwe ukuba malunga nesiqingatha sabantu abanesifo bane -gene engalunganga ebangela ukuba iiseli zeLangerhans zikhule zingalawuleki. Okubalulekileyo kukuba, olu tshintsho lwe-genetic (uguquko) lwenzeka emva kokuzalwa. Oku kuthetha ukuba asisosifo esizuzwe njengelifa kubazali .
Ukongeza, abaphandi bacinga ukuba kukho ezinye izinto ezininzi ezinokuchaphazela oku:
- Ukutshaya.
- Ukuvezwa kwabazali kwiityhefu ezingcolisayo ezifana ne-benzene okanye uthuli lomthi.
- Usulelo kwixesha losana olusandul' ukuzalwa.
- Ukuba nembali yosapho yesifo se-thyroid.
Zithini iindlela zonyango zoku?
I-chemotherapy ngamanye amaxesha isetyenziselwa ukunyanga i-LCH, njengoko isetyenziselwa ukunyanga ezinye iintlobo zomhlaza. Ngenxa yoko, abantu abaninzi abanale sifo banyanyekelwa ngoogqirha be-oncologists kunye neengcali zegazi.
Kodwa khumbula, ngokungafaniyo nomhlaza, iintlobo ezithile ze-LCH ngamanye amaxesha ziyaphela ngokwazo ngaphandle konyango.
Makhe sibone ukuba zeziphi iindlela zonyango ezikhoyo kwitheyibhile engasezantsi.
| Indlela yonyango | Ingcaciso elula |
|---|---|
| Unyango ngamakhemikhali | Ukunika amayeza okutshabalalisa iiseli ezigulayo. |
| Unyango ngemitha | Imitha yelanga ephantsi ithunyelwa kuphela kwinxalenye yomzimba echaphazelekileyo sesi sifo. |
| Utyando | Ukususwa kweethumba okanye izilonda ezibangelwe yi-LCH ngotyando. |
| IiSteroids | Ukunika ii-steroids okanye amanye amayeza okulwa nokuvuvukala afana ne-prednisone. |
| Unyango lokukhanya kwe-UV | Unyango lweengxaki zesikhumba kusetyenziswa ukukhanya okukhethekileyo. |
| Ukufakelwa kweeseli zesiqu | Indlela yonyango ethathwa njengefanelekileyo kwiimeko ezinzima kakhulu. |
Uninzi lwabantu abane-LCH bayaphola emva konyango. Ukuba esi sifo sichaphazele i-spleen yakho, isibindi, okanye umongo wethambo, sibizwa ngokuba yi-'high-risk LCH'. Kwanakule meko, malunga ne-80% yabantu bayaphola ngokupheleleyo . Ngoko ke kubalulekile ukuhlala unethemba.
Umyalezo Wokuya Ekhaya
- I-LCH sisifo esingaqhelekanga. Ayisosisifo somhlaza ngokwaso, kodwa siphathwa ngendlela efanayo nomhlaza.
- Nangona oku kubonakala kakhulu kubantwana abancinci, kunokukhula nakubani na wanoma yiphi na iminyaka.
- Ukuba uneempawu ezifana nezilonda zesikhumba, iintlungu zamathambo, okanye ukudumba, musa ukuzityeshela.
- Ukuba wena okanye umntwana wakho ninamathandabuzo ngezi mpawu, qiniseka ukuba ubonana nogqirha wakho . Musa ukoyika kwaye uzame ukuzixilonga kwi-intanethi.
- Ngonyango olufanelekileyo, uninzi lwezigulane ze-LCH ziyachacha ngokupheleleyo. Ngoko ke, kubaluleke kakhulu ukulandela iingcebiso zonyango ezifanelekileyo.
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