Ngaba wena okanye umntu osondeleyo kuwe unikwe inaliti ebizwa ngokuba yi-`Ceftazidime; Avibactam` ngugqirha? Okanye ngaba unomdla wokwazi ngale yeza? Abanye abantu bayalazi eli yeza ngegama lalo lophawu `(AVYCAZ)`. Ngoko ke, namhlanje siza kuthetha ngale yeza ngendlela elula neyobuhlobo, ukuba lisetyenziselwa ntoni, lisetyenziswa njani, kwaye zeziphi izinto ekufuneka uzilumkele.
Masiqale sibone ukuba le yeza yintoni?
Ngamafutshane, i-`Ceftazidime; Avibactam` sisibulali-ntsholongwane esikwiklasi ye-`cephalosporin`, oko kuthetha ukuba ' isibulali-ntsholongwane' . Khawucinge nje, kukho iintsholongwane eziyingozi ezingena emizimbeni yethu, kwaye eli yeza lisetyenziselwa ukunyanga izifo ezibangelwa ziintsholongwane ezinjalo. Umzekelo, linikwa izifo zomchamo, izifo zemiphunga (ezifana ne-pneumonia), okanye ezinye izifo zesisu.
Nangona kunjalo, into enye ekufuneka uyikhumbule kukuba eli yeza lisebenza kuphela kwiintsholongwane ezibangelwa ziintsholongwane. Alinyangi izifo ezibangelwa ziintsholongwane ezinje ngomkhuhlane, umkhuhlane, kunye nokukhwehlela. Ngenxa yoko, eli yeza linikwa kuphela emva kokuba ugqirha ehlolisise isigulana waza waqinisekisa ukuba sisifo esibangelwa ziintsholongwane.
Oogqirha ngamanye amaxesha banokusebenzisa eli yeza ngezinye izizathu. Ukuba unemibuzo malunga noku, buza ugqirha wakho okanye ikhemisti.
Zeziphi izinto ekufuneka uzixelele ugqirha?
Ngaphambi kokuba unikwe eli yeza, kukho izinto ezimbalwa ekufuneka uzixelele ugqirha wakho, umongikazi okanye iqela lakho lezempilo. Oku kubaluleke kakhulu kuba kuya kuqinisekisa ukuba eli yeza likulungele na kwaye lingakanani na onokulinikwa.
- Iingxaki zokopha okanye iimeko apho igazi lingajiyi lula: Ukuba unengxaki enjalo.
- Isifo sezintso: Ukuba unesifo sezintso. Kuba eli yeza likhutshwa emzimbeni ngezintso. Ngoko ke ukuba izintso azisebenzi kakuhle, umthamo weyeza unokufuneka utshintshwe.
- Iingxaki zesisu okanye zamathumbu: Umzekelo, ukuba ukhe waba neemeko ezifana ne-colitis, imeko yokuvuvukala kwamathumbu.
- Iimeko zokunganyamezelani:
- Ukuba ukhe waba ne-allergy kwi-Ceftazidime, ezinye ii-antibiotics ze-cephalosporin, okanye ii-antibiotics ze-penicillin ngaphambili.
- Ukuba une-aleji engaqhelekanga kuyo nayiphi na enye imithi, ukutya, iidayi zokwenziwa, okanye izithinteli.
- Kulungile ukuba ukhulelwe okanye unethemba lokukhulelwa.
- Ukuba ungumama oncancisayo.
Kubaluleke kakhulu ukuxelela ugqirha wakho ezi zinto ngokuchanekileyo.
Ulisebenzisa njani eli yeza?
Eli yeza lidla ngokunikezelwa njengenaliti emthanjeni . Ngokuqhelekileyo, eli yeza linikwa ngumsebenzi wezempilo esibhedlele okanye eklinikhi.
Nangona kunjalo, kwezinye iimeko, ugqirha wakho angakuxelela ukuba uthabathe eli yeza ekhaya. Ukuba kunjalo, uya kufundiswa ngqo indlela yokulungiselela inaliti kunye nendlela yokuzinika yona (okanye umntu akuncede ukukunika yona). Kubaluleke kakhulu ukusela iyeza kanye njengoko ugqirha okanye umongikazi wakho ekuxelela, ngexesha elifanelekileyo, ngomlinganiselo ofanelekileyo. Kufuneka uqhubeke nokusela iyeza de ugqirha wakho akuxelele ukuba uyeke.
Kubalulekile: Ukuba usebenzisa iziyobisi ekhaya, musa ukuphosa iinaliti ezisetyenzisiweyo kunye neesirinji kwinkunkuma. Kukho isitya esikhethekileyo sazo (isitya sezinto ezibukhali). Kulapho kufuneka zibekwe khona. Cinga ngako, ukuba uziphosa kwinkunkuma, umntu okhupha inkunkuma unokuhlatywa yinaliti, akunjalo? Oko kunokuba yingozi enkulu. Ukuba awunaso isitya sezinto ezibukhali, cela ikhemisti okanye ugqirha wakho akunike esinye.
Ubanika nini abantwana eli yeza?
Eli yeza linokunikwa iintsana ezineminyaka emi-3 ubudala kwezinye iimeko ezikhethiweyo. Nangona kunjalo, kukho amanyathelo athile okhuseleko akhethekileyo ekufuneka athathwe xa unika abantwana eli yeza. Ke ngoko, ukuba unika umntwana wakho eli yeza, thetha nogqirha wakho ngalo ngononophelo kwaye ulandele imiyalelo ngokuchanekileyo.
Kwenzeka ntoni ukuba uthatha kakhulu? (`Umthamo ogqithisileyo`)
Ukuba ucinga ukuba usele kakhulu eli yeza, yiya kwigumbi likaxakeka lesibhedlele esikufutshane okanye utsalele umnxeba kwiziko lokulawula ityhefu ngoko nangoko. Musa ukuchitha ixesha.
Ungalibali: Eli yeza lelakho wedwa. Ungaze unike omnye umntu iyeza lakho, nokuba unesifo esifana nesakho.
Kuthekani ukuba ndiphoswa yidosi?
Kubaluleke kakhulu ukusela eli yeza kanye ngendlela ekufanele lithathwe ngayo. Ukuba ungumntu oya esibhedlele okanye ekliniki ukuze ufumane amayeza akho, kwaye awukwazi ukuya ngexesha, fowunela ugqirha wakho ngoko nangoko.
Ukuba usela amayeza akho ekhaya, ukuba uphoswe yidosi, yithathe ngokukhawuleza xa ukhumbula. Nangona kunjalo, ukuba sele kusondele ixesha lokusebenzisa idosi yakho elandelayo, yitsibe idosi oyiphosileyo uze uthathe idosi yakho elandelayo ngexesha elicwangcisiweyo. Ungaze uthathe iidosi ezimbini ngaxeshanye.
Ngaba kukho iingxaki ngamanye amayeza? (`Ukusebenzisana`)
Ewe, eli yeza elithi "Ceftazide; Avibactam" linokusebenzisana namanye amayeza owasebenzisayo. Oku kuthetha ukuba xa lisetyenziswa kunye nelo yeza, nokuba isiphumo salo yeza sinokuncitshiswa, okanye isiphumo salo elinye iyeza sinokuncitshiswa/sinyuswe, okanye iziphumo ezitsha ezingalindelekanga zinokuvela.
Amanye amayeza anokubangela iingxaki ngale mayeza ngala:
- Iipilisi zokulawula inzala:Ukusela eli yeza kunokunciphisa ukusebenza kweepilisi zokulawula ukukhulelwa. Ngoko ke, kufuneka uthethe nogqirha wakho kwaye ucinge ngokusebenzisa enye indlela yokulawula ukukhulelwa.
- Ezinye iintlobo ' zee-antibiotics ': Umzekelo, 'amikacin', 'chloramphenicol', 'gentamicin', 'tobramycin'.
- Amayeza okunyusa ukuchama (i-diuretics)
- I-Probenecid (iyeza le-gout)
- I-Warfarin ( iyeza lokunciphisa igazi)
Olu luhlu aluphelelanga. Ngoko ke, kufuneka uxelele ugqirha wakho ngawo onke amayeza owasebenzisayo (amayeza amiselweyo, athengiswa ngaphandle kwemvume kagqirha, awezityalo, iivithamini, kunye nezongezo zokutya). Kwakhona, xelela ugqirha wakho ukuba uyatshaya, usela utywala, okanye usebenzisa iziyobisi ezingekho mthethweni. Ezinye zezi zinto zinokuchaphazela amayeza akho.
Izinto ekufuneka uzilumkele xa usebenzisa amayeza
Ukuba iimpawu zakho aziphucuki ngelixa usebenzisa eli yeza, okanye ukuba ubonakalisa iimpawu ezintsha, xelela ugqirha wakho ngoko nangoko. Ugqirha wakho uza kujonga imeko yakho aze, ukuba kuyimfuneko, enze uvavanyo lwegazi.
Iimpendulo eziqatha zesikhumba ezinokubakho
Eli yeza linokubangela ukusabela okukhulu kwesikhumba kwabanye abantu. Oku kunokwenzeka kwiiveki okanye kwiinyanga emva kokuba uqalile iyeza. Xelela ugqirha wakho ngoko nangoko ukuba ufumana umkhuhlane okanye irhashalala enomkhuhlane. La marhashalala anokuba bomvu okanye abe mfusa, aze emva koko abe namaqhubu aze aqhekeke. Okanye ukuba unerhashalala ebomvu kunye nokudumba kobuso okanye imilebe, okanye ii-lymph nodes ezivuvukileyo entanyeni okanye emakhwapheni, xelela ugqirha wakho ngoko nangoko. Ezi zinokuba ziimeko ezinzulu kakhulu.
Ukuphazamiseka kwesisu (urhudo)
Abanye abantu banokufumana isifo sohudo ngelixa besebenzisa eli yeza. Ukuba ufumana isifo sohudo, musa ukuthatha amayeza kwikhemesti. Ukuba unesifo sohudo kangangeentsuku ezingaphezu kwezimbini, okanye ukuba isifo sohudo sinzima kwaye sinamanzi, xelela ugqirha wakho ngoko nangoko.
Uvavanyo lweswekile yomchamo
Ukuba usebenzisa amayeza esifo seswekile, eli yeza elithi "ceftazidime; avibactam" lisenokutshintsha iziphumo zovavanyo lweglucose yomchamo. Ukuba usebenzisa olo vavanyo, thetha nogqirha wakho ngalo mba.
Ingaba kukho naziphi na iziphumo ebezingalindelekanga? Zithini?
Njengayo nayiphi na iyeza, eli yeza elithi "Cefacamide; Avibactam" linokubangela ezinye iziphumo ebezingalindelekanga. Nangona kunjalo, ayinguye wonke umntu ozifumanayo. Ezinye iziphumo ebezingalindelekanga ziyingozi kwaye kufuneka uxelele ugqirha wakho ngoko nangoko ukuba ziyavela. Ezinye azibi kakhulu kwaye kufuneka uxelele ugqirha wakho ukuba ziyaqhubeka okanye ziyakhathaza.
Iziphumo ebezingalindelekanga ekufuneka uzixelele ugqirha wakho ngoko nangoko ziquka:
- Iimpendulo ze-allergy: ukurhawuzelela kwesikhumba, ukurhawuzelela okanye ukurhawuzelela, ukudumba kobuso, imilebe, ulwimi.
- Umchamo omnyama
- Ubunzima bokuphefumla, ukuphefumla kancinci
- Ifiva
- Intlungu okanye ubunzima bokuchama
- Ubomvu, ukudumba, ukuxobuka okanye ukukhululeka kolusu, kuquka nangaphakathi emlonyeni
- Ukudideka, ukuxhuzula
- Ukopha okungaqhelekanga, ukudumba
Iziphumo ebezingalindelekanga ezihlala zingadingi ngcebiso kagqirha (kodwa kufuneka zixelwe kugqirha ukuba ziyaqhubeka okanye ziyakhathaza):
- Ukungazoli, ixhala `(ukukhathazeka)`
- Ukuqhinwa
- Urhudo
- Isiyezi
- Isicaphucaphu, ukuhlanza
Olu luhlu alubandakanyi zonke iziphumo ebezingalindelekanga. Ukuba ubona nantoni na engaqhelekanga ukongeza kwezi, qhagamshelana nogqirha wakho.
Uligcina njani iyeza?
Gcina eli yeza kude nabantwana kunye nezilwanyana zasekhaya.
Ukuba unikwe eli yeza ukuba ulisebenzise ekhaya, uza kunikwa imiyalelo yokuba ungaligcina njani. Ngokuqhelekileyo kufuneka ligcinwe kude nokukhanya. Musa ukusebenzisa amayeza asele edlulile "umhla wokuphelelwa" kwaye uwalahle.
Izinto ezibaluleke kakhulu ekufuneka sizikhumbule
Kulungile, ngoko ke ngokwento esithethe ngayo, ndicinga ukuba unoluvo oluhle malunga nenaliti ebizwa ngokuba yi-`Ceftazidime; Avibactam` okanye `(AVYCAZ)`.
Khumbula: Eli nqaku lisisishwankathelo nje. Lisenokungagubungeli lonke ulwazi. Ukuba unemibuzo engaphezulu malunga neli yeza, ungathandabuzi ukubuza ugqirha wakho, ikhemisti, okanye omnye umboneleli wezempilo. Baya kukwazi ukukunceda.
Izinto eziphambili ekufuneka uzikhumbule zezi:
- Le yi- antibiotic enikwa izifo ezibangelwa ziintsholongwane.
- Qiniseka ukuba uxelela ugqirha wakho ngezinye izifo onazo, amayeza owasebenzisayo, kunye nee-allergies.
- Sela amayeza kanye njengoko ugqirha ekuxelela, ngexesha elifanelekileyo, ngomlinganiselo ofanelekileyo. Gqibezela ikhosi.
- Ukuba ufaka inaliti ekhaya, lahla iinaliti ngokufanelekileyo kwisikhongozeli esibukhali.
- Ukuba ufumana naziphi na iziphumo ebezingalindelekanga ezinzulu (ingakumbi ukusabela kwesikhumba, ubunzima bokuphefumla), xelela ugqirha wakho ngoko nangoko.
- Musa ukunika omnye umntu amayeza akho.
Ndikunqwenelela ukuchacha ngokukhawuleza!
👩🏽⚕️ Imibuzo eyongezelelweyo (Ii-FAQ)
💬 Ingaba iCeftazidime; iAvibactam / iAVYCAZ sisibulali-ntsholongwane esiqhelekileyo?
Hayi suka! Olu lugonyo olunamandla kakhulu lwe-'ICU/intensive care unit' olunama-antibiotic amabini olungenakuthengwa kwikhemesti eqhelekileyo. Oogqirha basebenzisa olu nyango njengeyeza lokugqibela lokubulala iintsholongwane 'zeSuperbugs - MDR bacteria' ezinganyangekiyo/ezingafiyo kuzo zonke ezinye ii-antibiotics ezikhoyo kumayeza, njenge-amoxicillin eqhelekileyo kunye ne-cephalexin.
💬 Kutheni i-'Avibactam' entsha ixutywa ne-Ceftazidime eqhelekileyo?
Le yimfihlelo enkulu! Kwezo bhaktiriya ziqinileyo (ezifana ne-KPC), kwenziwa isikere esahlukileyo sekhemikhali (i-enzyme ye-Beta-lactamase) ukutshabalalisa iyeza eliqhelekileyo le-Ceftazidime kwangoko nje ukuba lingene emzimbeni. Ngelo xesha, eli joni elibizwa ngokuba yi-Avibactam liyahamba lize livale/litshabalalise isikere sekhemikhali saloo bhaktiriya. Emva koko, iyeza le-Ceftazidime linokuqhubeka ngaphandle koloyiko lize liqhumise udonga lwebhaktiriya lize liyibulale (iTeamwork).
💬 Zinjani izigulane ezifumana olu gonyo luphezulu (AVYCAZ)? Ngaba kukho naziphi na iziphumo ebezingalindelekanga?
Eli linikwa izigulana ezigula kakhulu ezinezifo ezintsonkothileyo zangaphakathi esiswini (CIAI), ii-UTI/Pyelonephritis, kunye ne-hospital-acquired pneumonia (HAP). Iziphumo ebezingalindelekanga zale mayeza ziquka urhudo olunzima (C. diff diarrhea), ukuhlanza, kunye nokusebenza kwezintso okunciphileyo, ngoko ke linikwa kuphela esibhedlele phantsi koqwalaselo olusondeleyo.
I- Ceftazidime, i-Avibactam, i-AVYCAZ, i-antibiotic , usulelo lwebhaktiriya, inaliti, iziphumo ebezingalindelekanga, i-cephalosporin
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