Xa ufunyaniswa ukuba unomhlaza uze uqale unyango, kuyinto eqhelekileyo ukuziva uxinezelekile kwaye udidekile. Kodwa ngenxa yezonyango eziphucukileyo namhlanje, kukho amayeza anokujolisa kwaye atshabalalise iiseli zomhlaza kuphela. I-Ceritinib yenye yeziyobisi ezinjalo, eziphucukileyo kakhulu, ezikhethekileyo. Ngoko ke ukuba wena okanye umntu omaziyo unikwe eli yeza, kubaluleke kakhulu ukwazi ukuba liyintoni kanye kanye. Masithethe ngale nto ngokulula.
Luhlobo luni lweyeza iCeritinib?
Ngamafutshane, iCeritinib "lunyango olujoliswe kulo." Oku kuthetha ukuba eli yeza lijolise ngqo kwiiproteni ezithile ezinceda iiseli zomhlaza zikhule. Xa ezo proteni ziyeka ukusebenza, iiseli zomhlaza zilahlekelwa ngamandla azo okwahlukana nokukhula.
Eli yeza lisetyenziswa kakhulu ukunyanga "umhlaza wemiphunga ongengoweeseli ezincinci." Endaweni yokuba lichaphazele iiseli emzimbeni wonke njenge-chemotherapy eqhelekileyo, lijolise ngokukodwa kwiiseli zomhlaza, ezinokunciphisa ezinye zeziphumo ebezingalindelekanga. Kodwa akufani kuye wonke umntu. I-Zykadia ligama lophawu oludumileyo lwale yeza.
Izinto ekufuneka uzixelele ugqirha wakho ngaphambi kokuba uqale amayeza
Ngaphambi kokuba ugqirha wakho akunike eli yeza, kubalulekile ukuba ube nomfanekiso opheleleyo wempilo yakho. Oku kubaluleke kakhulu kukhuseleko lwakho. Ke ngoko, ukuba unayo nayiphi na kwezi meko zidweliswe ngezantsi, qiniseka ukuba uxoxa ngayo nogqirha wakho.
- Ukuba unesifo seswekile okanye amanqanaba aphezulu eswekile egazini.
- Ukuba unembali yesifo sentliziyo okanye ukubetha kwentliziyo okungaqhelekanga.
- Ukuba ukhe waba ne-pancreatitis ngaphambili.
- Ukuba unesifo sesibindi.
- Ukuba unezinga eliphantsi le-magnesium okanye i-potassium egazini lakho.
- Ukuba unesifo semiphunga okanye sokuphefumla esifana ne-asthma.
- Ukuba uzama ukukhulelwa, sele ukhulelwe, okanye uncancisa.
- Ukuba une-allergy kule mithi yeCeritinib, i-lactose, i-gelatin, okanye nayiphi na enye iyeza, ukutya, okanye isithinteli.
Ndingayisebenzisa njani le mithi?
Ukulandela imiyalelo echanekileyo yokusebenzisa eli yeza kubaluleke kakhulu kwimpumelelo yonyango.
- Yithathele nokutya: Eli yeza lifanele lithathwe kunye nesidlo kunye neglasi yamanzi. Musa ukulithatha ungenanto esiswini.
- Akukho grapefruit: Musa ukuyisebenzisa le mithi kunye negrapefruit okanye ijusi yayo. Ingatshintsha indlela amayeza angena ngayo emzimbeni.
- Musa ukuphula okanye ukutyumza ithebhulethi: Ginya ithebhulethi yonke. Musa ukuyiqhekeza, ukuyityumza, okanye ukuyihlafuna.
- Yithathe ngexesha: Yithathe kanye njengoko ugqirha wakho ekuxelele, ngexesha elifanelekileyo, ngomlinganiselo ofanelekileyo. Musa ukuyeka ukuthatha iyeza okanye utshintshe umthamo ngaphandle kwengcebiso kagqirha.
Kubalulekile: Ukuba unesikrokro sokuba usele kakhulu eli yeza, ungoyiki kwaye ngoko nangoko fowunela iZiko loLwazi lweeTyhefu kwiSibhedlele sikaZwelonke saseColombo . Okanye yiya kwiYunithi yoNyango oluNgxamisekileyo (ETU) yesibhedlele esikufutshane.
Yintoni omawuyenze ukuba uphoswe yidosi yeyeza?
Khawucinge ukuba ulibele ukusela amayeza akho. Ungakhathazeki. Ukuba kudlule iiyure ezingaphezu kwe-12 ngaphambi komthamo wakho olandelayo, thatha umthamo owuphosileyo ngokukhawuleza xa ukhumbula. Nangona kunjalo, ukuba kungaphantsi kweeyure ezili-12 ngaphambi komthamo wakho olandelayo, yeka umthamo owuphosileyo uze uthathe umthamo wakho olandelayo ngexesha elicwangcisiweyo. Ungaze uthathe iidosi ezimbini ngaxeshanye.
Amanye amayeza anokusebenzisana ne-ceritinib (i-Drug Interactions)
I-Ceritinib liyeza elinamandla amakhulu okusebenzisana namanye amayeza. Ngoko ke, kubalulekile ukuxelela ugqirha wakho malunga nawo onke amayeza owasebenzisayo, kuquka iivithamini, amayeza emifuno, kunye nezongezo.
| MUSA ukuthatha iCeritinib kunye nala mayeza. | |
|---|---|
| I-Alfuzosin | ILovastatin, iSimvastatin |
| Amayeza okulwa nefungus afana neFluconazole kunye neVoriconazole | ICisapride, iDronedarone |
| Ii-alkaloids ze-Ergot ezifana ne-ergotamine | I-Pimozide, i-Thioridazine |
| I-Lurasidone, iLomitapide | I-Triazolam, iTolvaptan |
| Ingasebenzisana nala mayeza | |
|---|---|
| Amanye amayeza okulwa ne-HIV/AIDS | Amanye amayeza okubulala iintsholongwane, njenge-clarithromycin |
| Amayeza okulwa nesifo sokuwa afana neCarbamazepine kunye nePhenytoin | I-Warfarin (i-blood thinner) |
| I-St. John's Wort (isicatshulwa semifuno) | Amanye amayeza atshintsha izinga lentliziyo (amayeza okwandisa ixesha le-QT) |
Izinto ekufuneka uzilumkele xa usebenzisa amayeza
Zikhusele kwiintsholongwane
Eli yeza linokwenza buthathaka amandla omzimba wakho okulwa nezifo, oko kukuthi, amasosha omzimba wakho. Ke ngoko,
- Ukuba ubonakalisa iimpawu ezifana nomkhuhlane, umkhuhlane, okanye umphimbo obuhlungu, musa ukuzinyanga kwaye uxelele ugqirha wakho.
- Zama ukuphepha iindawo ezinabantu abaninzi kunye nabantu abagulayo. Hlamba izandla zakho rhoqo.
- Musa ukuthatha amayeza okudambisa iintlungu afana ne-aspirin kunye ne-ibuprofen ngaphandle kwengcebiso kagqirha wakho. Anganciphisa umkhuhlane wakho kwaye enze kube nzima ukubona usulelo.
Ukwaziswa okukhethekileyo malunga nokukhulelwa nokuncancisa
Oku kubaluleke kakhulu: Kuphephe ukukhulelwa ngokupheleleyo ngelixa usebenzisa eli yeza. Akucetyiswa ukuba ukhulelwe iinyanga ezi-6 emva kokuyeka ukusebenzisa eli yeza. Ukuba indoda ithatha eli yeza, kufuneka iphephe ukuba nguyise womntwana ngelixa ithatha eli yeza kwaye iinyanga ezi-3 emva kokuliyeka. Ukuba ungumama oncancisayo, kufuneka uphephe ukuncancisa ngelixa usebenzisa eli yeza kwaye iiveki ezi-2 emva komthamo wokugqibela.
Lumka ilanga.
Eli yeza lingenza ulusu lwakho lube buthathaka elangeni. Ngoko ke, ukuba uza kuba selangeni, nxiba impahla egqunywe kakuhle kwaye usebenzise isithambisi selanga.
Iziphumo ebezingalindelekanga ezinokubakho ngenxa yamayeza
Njengalo naliphi na iyeza, iCeritinib inokuba nemiphumo emibi. Ezinye zezi zifuna ingqalelo ekhawulezileyo.
| Ukuba ufumana ezi mpawu, yazisa ugqirha wakho ngoko nangoko. | |
|---|---|
| Ukunganyamezelani kolusu | Ukurhawuzelela kwesikhumba, ukurhawuzelela, ukudumba kobuso, imilebe, ulwimi. |
| Ubunzima bokuphefumla | Ubunzima bokuphefumla, ukuqina kwesifuba, ukukhohlela. |
| Iingxaki zentliziyo | Intlungu esifubeni, isiyezi, ukuziva ngathi intliziyo yakho ibetha ngokukhawuleza okanye ngokungacwangciswanga, ukuphelelwa ngamandla. |
| Iimpawu zomonakalo wesibindi | Umchamo otyheli/omdaka omnyama, ukutyheli kwamehlo okanye ulusu, iintlungu kwinxalenye ephezulu ngasekunene yesisu, ukudinwa kakhulu. |
| Iimpawu zeswekile ephezulu egazini | Umlomo owomileyo, ukoma kakhulu okanye indlala, ukuchama rhoqo. |
| Ezinye iimpawu ezinzulu | Intlungu ebuhlungu esiswini, umkhuhlane, ukubanda, ukopha okungaqhelekanga okanye ukukrweleka. |
| Ukuba ezi ziphumo bezingalindelekanga ziyaqhubeka okanye ziyakhathaza, xelela ugqirha wakho. | |
| Iziphumo ebezingalindelekanga eziqhelekileyo | Urhudo, ukuqhina, isicaphucaphu, ukuhlanza, intloko ebuhlungu, isiyezi, ukudinwa kakhulu. |
Olu luhlu alubandakanyi zonke iziphumo ebezingalindelekanga. Ukuba ufumana naziphi na iimpawu ezintsha okanye ezingaqhelekanga, thetha nogqirha wakho ngazo.
Umyalezo Wokuya Ekhaya
- Soloko usela i-ceritinib xa usitya . Sukuyisela nejusi yegrapefruit.
- Xelela ugqirha wakho ngazo zonke ezinye iziyobisi, iivithamini, kunye neemveliso zezityalo ozisebenzisayo.
- Kubaluleke kakhulu ukuphepha ukukhulelwa ngokupheleleyo ngelixa usebenzisa eli yeza kwaye kangangoko ugqirha wakho ecebisa.
- Xelela ugqirha wakho ngokukhawuleza ukuba ufumana iziphumo ebezingalindelekanga ezinzulu ezifana neentlungu zesifuba, ubunzima bokuphefumla, okanye ukutyheli kwamehlo.
- Musa ukuyeka unyango nangasiphi na isizathu ngaphandle kwengcebiso kagqirha wakho. Kubalulekile ukuqhubeka nonyango, nokuba uziva ungakhululekanga. Thetha nogqirha wakho ngayo nayiphi na into ekuxhalabisayo.
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