Ingaba umzimba wakho uhlala ubuhlungu? Isenokuba sisifo sezicwili ezidityanisiweyo!

Khawucinge nje ukuba imizimba yethu ifana nesakhiwo esakhiwe kakuhle. Kule sakhiwo, yonke into efana nezitena, iindonga, uphahla, imiqadi, njl.njl., ifuna isamente kunye nocingo ukuze izidibanise kwaye zihlale zomelele, akunjalo? Ngokufanayo, amalungu omzimba, izihlunu, amathambo, kunye nemithambo-luvo emzimbeni wethu zidibene, zixhaswa, kwaye zikhuselwe luthungelwano olukhethekileyo lwezicubu ezibizwa ngokuba yi-'Connective Tissues'. Ezi zisasazeka kuwo wonke umzimba wethu.

Ngamafutshane, yintoni le tissue inxibelelanayo?

Ezi 'ziinkuni' kunye 'nesakhelo esixhasayo' semizimba yethu. Kunzima ukufumana indawo emzimbeni wakho engenazo. Umzekelo:

• Amathambo: Yisakhelo esinika imizimba yethu imo namandla.
• I-Cartilage: Yindawo engathi yi-sponge phakathi kwamalungu ethintela amathambo amabini ukuba angakhuhlani.
• Iiligamenti: Iibhanti eziqinileyo ezidibanisa amathambo.
• I-tendon: Ibhendi edibanisa izihlunu namathambo.
• Ulusu: Lugquma kwaye lukhusela imizimba yethu.
• Amafutha omzimba: agcina amandla kwaye akhusela amalungu omzimba.
• I-Fascia: I-membrane encinci ejikeleze izihlunu kunye namalungu omzimba.

Ngoku uyaqonda ukuba le mixture ibaluleke kangakanani emzimbeni wethu. Ngoko ke, ukuba kukho nasiphi na isifo esichaphazela le mixture, sinokuchaphazela iindawo ezininzi emzimbeni, kungekhona enye kuphela. Eli liqela lezifo esizibiza ngokuba yiConnective Tissue Diseases .

Zingaphi iintlobo eziphambili ezi zifo ezahlulwe ngazo?

Kukho iintlobo ezingaphezu kwama-200 zezifo zezicubu ezidityanisiweyo, kodwa singazahlula zibe ngamaqela amathathu aphambili ngokusekelwe kuhlobo lwazo.

Ngoku makhe sijonge nganye kwezi ndidi ngokweenkcukacha ezithe vetshe.

1. Izifo zeZicwili eziQhagamshelana neZilwanyana eziZikhuselayo

Yile nto abantu abaninzi abayicingayo xa besiva igama elithi 'isifo sezicubu ezidityanisiweyo'. Kulapho inkqubo yomzimba wethu yokuzikhusela icinga ngempazamo ukuba iiseli zethu kunye nezicubu 'ziintshaba' ize izihlasele. Oku kubangela ukudumba okungapheliyo , okanye ukudumba okuqhubekayo kunye nokudumba, kwiindawo ezahlukeneyo zomzimba. Ekuhambeni kwexesha, oku kunokukhokelela ekonakaleni okungapheliyo kwezicubu.

Imizekelo eqhelekileyo:

• I-rheumatoid arthritis: Oku kuchaphazela kakhulu amalungu. Amalungu ayadumba, aqine, kwaye abe buhlungu. Ukuba awanyangwa kakuhle, amalungu anokuwohloka. Ngamanye amaxesha, oku kuvutha kunokusasazeka kwimithambo yegazi nakwezinye izitho zomzimba.
• I-Lupus: Le inzima ngakumbi kuba i-lupus inokuchaphazela nayiphi na izicubu zomzimba, kwaye ngamanye amaxesha yonke. Ingonakalisa amalungu amakhulu afana nolusu, amalungu, intliziyo, imiphunga kunye nezintso.
• I-Scleroderma: Kule meko, umzimba uvelisa iproteni eninzi ebizwa ngokuba yi-collagen kunokuba kufanele. I-Collagen yiyo enika izicubu zethu amandla. Kodwa xa isiba ninzi kakhulu, ulusu kunye namalungu omzimba ayaqina kwaye aqine. Kufana nento ekufanele ukuba ibe ngerabha iba yiplastiki.
• Isifo sikaSjögren: Kule meko, inkqubo yomzimba yokuzikhusela ihlasela amadlala avelisa umswakama emizimbeni yethu (njengeedlala ezikrazulayo nezithende). Ngenxa yoko, iindawo ezifana namehlo, umlomo, ulusu, kunye nendlela yokuphefumla zomile kakhulu.
• I-Myositis: Oku kukudumba kwemisipha. Oku kubangela ukuba izihlunu zibe buthathaka kwaye umzimba uzive ungenabomi. Kwezinye iintlobo, ukudumba kwesikhumba kunokubakho.

Abanye abantu banokuba neempawu zezifo ezingaphezu kwesinye, kodwa banokuba neempawu zezifo ezininzi kunye. Esi sibizwa ngokuba yiMixed Connective Tissue Disease . Kwakhona, kukho iimeko apho ezinye zeempawu zikhona, kodwa azinakubekwa ngokuqinisekileyo njengesifo esinye.

2. Iingxaki zeZicwili eziXhumana neMvelo

Ezi zibangelwa kukuguquka kwezakhi zofuzo okuzuzwe njengelifa. Esi siphene sezakhi zofuzo sibangela iingxaki ekuvelisweni kweeproteni ezibizwa ngokuba yi-collagen okanye i-elastin, ezimbini zezona zinto ziphambili zokwakha izicwili ezidityanisiweyo.

• I-Collagen ifana neglu enika izicubu zethu amandla nokuqina.
• I-Elastin yinto enika ukuthamba, njengebhanti yerabha.

Xa ukuveliswa kwezi zinto kuphazamiseka, kubakho ubuthathaka obahlukeneyo kwizicubu.

Eminye imizekelo:

• I-Marfan syndrome: Le meko ichaphazela imicu ye-elastin, nto leyo eyenza izicubu zibe lula ngakumbi. Abantu abanale meko banemilenze emide kunesiqhelo. Inokubangela iingxaki ezinkulu kwintliziyo nakwimithambo yegazi.
• I-Ehlers-Danlos syndrome: Le yimeko apho ulusu kunye namalungu akhula ngokukhawuleza ngenxa yokuba buthathaka kwe-collagen. Amalungu aqhekeka lula kwaye ulusu luyenzakala lula.
• I-Osteogenesis imperfecta: Eyaziwa ngokuba 'sisifo samathambo abuthathaka', le yimeko apho umzimba ungenalo uhlobo lwe-collagen, nto leyo eyenza amathambo namazinyo abe buthathaka kakhulu. Nokuba ukuwa okuncinci kunokubangela ukuba ithambo liphuke.

Iimpawu zabantu abazelwe benesi sifo semfuza zingaqala kwezincinci ukuya kwezinzima kakhulu. Ekubeni kungekho ndlela yonyango lwesi siphene semfuza, oogqirha banyanga iimpawu kunye neengxaki ngokwahlukeneyo.

3. Umhlaza weethishu ezidityanisiweyo

Umhlaza oqala kwizicubu ezidityanisiweyo udla ngokubizwa ngokuba yi-sarcomas . Ezi zinokuqala emathanjeni, kwi-cartilage, kumafutha, kwimisipha, kwi-ligaments, kwi-tendon, okanye kwiindawo ezinzulu zolusu.

Eminye imizekelo:

• I-Osteosarcoma: Uhlobo lomhlaza oluqhelekileyo oluvela emathanjeni.
• I-Chondrosarcoma: Umhlaza wamathambo oqala kwi-cartilage.
• I-Liposarcoma: Ithumba eliqala kwizicubu ezinamafutha emzimbeni.
• I-Myxofibrosarcoma: Idla ngokuqala njengeqhubu elingaphantsi kwesikhumba sengalo okanye umlenze.

Ziziphi iimpawu eziqhelekileyo zezi zifo?

Nangona zininzi iintlobo zezi zifo, zineempawu ezifanayo. Ekubeni ezi zifo zichaphazela umzimba wonke, iimpawu zinokuhluka kakhulu.

• Intlungu yemisipha namalungu, ukuqina, kunye nobuthathaka: Olu luphawu oluqhelekileyo lwezifo ezininzi. Izinto ezifana nokuqina kwasekuseni, ukudumba kwamalungu, kunye nentlungu xa uhamba.
• Ukudinwa: Ukudinwa kakhulu okuvakalayo nasemva kokuba ungenzi nto.
• Iziphumo kwimiphunga nentliziyo:Imiphunga yethu inezicwili ezininzi ezinxibelelanayo. Ngenxa yokuba imithambo yegazi ihamba phakathi kwezicwili, ukudumba kwindawo enye kunokusasazeka lula kwezi zitho. Oku kunokubangela iimpawu ezinje ngobunzima bokuphefumla, iintlungu zesifuba, kunye notshintsho kuxinzelelo lwegazi .
• Iimpawu zeSarcomas: Ezi zihlala zingabonisi zimpawu de zibe nkulu. Ngamanye amaxesha zinokubonakala njengeqhubu elingenabuhlungu phantsi kolusu . Okanye zinokuqala njengentlungu yamathambo okanye yamalungu.

Yenziwa njani le nto yokuxilonga?

Emva kokumamela iimpawu zakho, ugqirha uza kukuhlola. Ukongeza, unokuyalela iimvavanyo ezahlukeneyo ngokuxhomekeke kwisifo ocinga ukuba unesifo.

• Uvavanyo lwegazi: Uvavanyo olufana ne -ESR kunye ne-C-reactive protein , ezilinganisa ukudumba emzimbeni, kunye novavanyo lwee -antibodies ezithile zokufumanisa izifo ezizikhuselayo emzimbeni.
• Uvavanyo lwemifanekiso: Ii-X-ray kunye nee-MRI scans ukujonga imeko yamalungu kunye namathambo.
• I-Biopsy: Ukuthatha iqhekeza elincinci lesicwili kwiqhubu okanye ulusu olukrokrelekayo uze ulihlolisise nge-microscope.
• Ezinye iimvavanyo: Uvavanyo olulinganisa ukoma kwamehlo okanye umlomo, uvavanyo lomchamo, njl.

Zithini iindlela zonyango?

Izifo ezininzi zezicubu ezidityanisiweyo zizinto ezibangela ubomi bonke. Oku kuthetha ukuba kunzima ukuzinyanga ngokupheleleyo. Nangona kunjalo, ngonyango olufanelekileyo, iimpawu zinokulawulwa, isifo sinokuthintelwa ukuba singabi mandundu, kwaye ungaphila ubomi obuqhelekileyo.

• Kwizifo ezithintela amasosha omzimba: Amayeza anjenge -immunosuppressants kunye ne -corticosteroids anikwa ukuthintela ukusebenza kwenkqubo yomzimba yokuzikhusela.
• Kwi-cancer (sarcomas): Iindlela zonyango ezinje ngotyando, i-chemotherapy, kunye nonyango lwe-radiation ziyasetyenziswa.
• Kwizifo zemfuza: Nangona okwangoku kungekho nyango lwazo, iimpawu (umz. iingxaki zentliziyo, ukwaphuka kwamathambo) zinyangwa nganye nganye.
• Unyango Lomzimba: Ukuzilolonga kunye nonyango lomzimba kubaluleke kakhulu ekunciphiseni iintlungu kwimisipha namalungu kunye nokubuyisela ukusebenza kwazo.

Ukuba unesifo esinjalo, ugqirha wakhoKubaluleke kakhulu ukulandela imiyalelo enikiweyo ngokuchanekileyo nokuya kwiikliniki ngexesha.