Ngaba ngamanye amaxesha uziva udiniwe kakhulu? Kwangaxeshanye, ngaba ukhe wazibona iimpawu ezingaqhelekanga ezifana neentlungu zamalungu, iminwe evuvukileyo, kwaye ngamanye amaxesha iminwe yakho ijika ibe luhlaza okwesibhakabhaka xa ichaphazeleka ngumkhuhlane? Ngaba ukhathazwa naziimpawu zezi zifo ezibonakala ngaxeshanye? Ngoko ke esi sisenokuba yimeko engaqhelekanga ebizwa ngokuba yiMixed Connective Tissue Disease, okanye iMCTD njengoko siyibiza ngokufutshane. Ungakhathazeki, masithethe ngale nto ngokulula.
Yintoni kanye kanye iMCTD?
Ngamafutshane, i-MCTD sisifo esibangelwa kukuzikhusela komzimba. Cinga ngale ndlela: inkqubo yokuzikhusela yomzimba wethu, inkqubo yokuzikhusela, ikhona ukuze isikhusele kwiintsholongwane ezibangela izifo. Kodwa kolu hlobo lwesifo, inkqubo yethu yokuzikhusela icinga ngempazamo ukuba izicubu zethu eziphilileyo ziintshaba kwaye iqala ukuzihlasela.
Eyona nto ingaqhelekanga nge-MCTD kukuba ayisosifo sithile, kodwa yindibaniselwano yeempawu zezinye izifo ezintathu eziphambili zezicubu ezidityanisiweyo. Yiyo loo nto ibizwa ngokuba yi-"Mixed". Ikwabizwa ngokuba yi-"overlap syndrome". Ezi zifo zintathu zezi:
- I-systemic lupus erythematosus (SLE): Sidla ngokuyibiza ngokuba yi-'lupus'.
- I-Scleroderma: Oku kubangela ukuba ulusu lube lukhuni kwaye luqine.
- I-Polymyositis: Oku kubangela ubuthathaka bemisipha kunye nokudumba.
Abanye abantu banokubonisa iimpawu zeemeko ezifana ne-dermatomyositis, i-rheumatoid arthritis, okanye i-Sjögren's syndrome ukongeza kwezi mpawu.
Zithini iimpawu ze-MCTD?
Amaxesha amaninzi, ezi mpawu azibonakali zonke ngaxeshanye. Zivela enye emva kwenye ngokuhamba kwexesha. Ke ngoko, kunokuba nzima ukuxilonga i-MCTD ekuqaleni.
| Uphawu | Ingcaciso elula |
|---|---|
| Ndiziva ndidiniwe kwaye ndingenabomi | Ukuhlala uziva udiniwe kakhulu ngaphandle kwesizathu. Ukuziva ngathi umzimba wakho awunabomi. |
| Ubushushu bomzimba (umkhuhlane) | Asikuko umkhuhlane ophezulu, kukufudumala nje okuncinci komzimba okuhlala kuhleli. |
| Intlungu yemisipha kunye namalungu | Iintlungu zemisipha kunye nobuthathaka, kunye nokudumba, amalungu aqinileyo kunye nentlungu. |
| Isiganeko sikaRaynaud | Olu luphawu oluqhelekileyo kubantu abaninzi. Xa bejamelene nomkhuhlane okanye bephantsi koxinzelelo, ukuhamba kwegazi ezandleni, ezinyaweni, empumlweni, nakwiindlebe kuyehla, nto leyo ebangela ukuba ngequbuliso batshintshe umbala, baze babe luhlaza okwesibhakabhaka. Emva koko baphinde babe bomvu baze babuyele esiqhelweni. Ungaziva ungenazimvakalelo okanye intlungu ngeli xesha. |
| Ukudumba kweminwe | Iminwe ivakala ngathi idumbile kwaye inezikhwekhwe. Ngamanye amaxesha oku kuyaphela emva kweentsuku ezimbalwa, kodwa ngokuhamba kwexesha, abanye abantu banokuba nokuqina kolusu okwenza kube nzima ukugoba iminwe yabo (i-sclerodactyly). |
| Amabala esikhumba | Amabala abomvu okanye abomvu-mdaka okanye izilonda ezikwiingqukuva. |
I-MCTD ivakalelwa njani xa ivutha?
Abantu abanesi sifo ngamanye amaxesha banokuba neempawu eziqatha kakhulu . Oku sikubiza ngokuba 'kukudumba'. Ngeli xesha, iintlungu zamalungu kunye neentlungu zemisipha zinokuba nzima ukuzinyamezela. Njengomntu one-'Rheumatoid arthritis', amalungu anokudumba, aqine, kwaye abe buhlungu. 'Isiganeko sikaRaynaud' sinokwenzeka rhoqo kwaye sibi kakhulu.
Yintoni ebangela i-MCTD?
Unobangela ochanekileyo wesi sifo awukafunyanwa. Asisisifo esizuzwe ngokugqithisileyo. Nangona kunjalo, uphando lufumanise ukuba ukuba umntu kusapho unezifo zezicubu ezidityanisiweyo, abanye basengozini ethile yokuphuhliswa kwaso. Ukongeza, kurhanelwa ukuba ezinye iintsholongwane, ukuvezwa kwiikhemikhali ezifana ne-'polyvinyl chloride' kunye ne-'silica' nazo zinokubangela oku.
Ngubani osengozini enkulu yokuhlaselwa sesi sifo?
I-MCTD ixhaphake kakhulu kubasetyhini abaphakathi kweminyaka engama-20 ukuya kwengama-40 ubudala.Phakathi. Kodwa oko akuthethi ukuba amadoda okanye abantu abaneminyaka eyahlukileyo abanakuyifumana. Nabani na, nokuba uneminyaka emingaphi, angayifumana le sifo.
Ziziphi iingxaki ezinokubakho ze-MCTD?
I-MCTD sisifo esinokubangela iingxaki ezinkulu ngamanye amaxesha, ngoko ke kubaluleke kakhulu ukugcina esi sifo silawulwa.
Khumbula, ayinguye wonke umntu oza kuba nazo zonke ezi ngxaki. Uninzi lwazo lunokuthintela ngonyango olufanelekileyo.
Nazi ezinye zeengxaki eziphambili:
- Uxinzelelo lwegazi oluphezulu kwimiphunga: Le yeyona nto iphambili ebangela ukufa phakathi kwezigulane ezine-MCTD. Yenzeka xa uxinzelelo kwimithambo yegazi ethwala igazi ukuya emiphungeni lusanda.
- Isifo semiphunga esingaphakathi kwesisu: Ukudumba kunye nokuqhekeka kwezicubu zemiphunga.
- Isifo sentliziyo
- Umonakalo wezintso
- Umonakalo kwindlela yokugaya ukutya
- I-anemia
- Ukufa kwezicubu (i-necrosis)
- Ukulahlekelwa kukuva
Ugqirha uyixilonga njani i-MCTD?
Njengoko besitshilo ngaphambili, iimpawu zesi sifo zinokuba nzima ukuzifumanisa kuba zibonakala kancinci kancinci ngokuhamba kwexesha. Kungathatha iminyaka ukufumanisa ukuba yi-MCTD na. Ukuba unale mpawu, kusenokwenzeka ukuba uthunyelwe kugqirha ogxile kwizifo zamalungu kunye nezomzimba, obizwa ngokuba yi-rheumatologist .
Ugqirha ukhangela izinto ezine eziphambili onokukrokrela ukuba une-MCTD:
1. Amanqanaba aphezulu ee-anti-U1-RNP antibodies egazini: Olu lolona vavanyo luphambili lokufumanisa i-MCTD.
2. Akukho ngxaki zinzima zezintso okanye zenkqubo yemithambo-luvo: Ezi ngxaki zihlala zinzima kubantu abane-lupus (SLE).
3. Ukubakho kwesifo samathambo esibi kunye noxinzelelo lwegazi oluphezulu emaphaphu: Ezi azibonakali zodwa kwi-lupus okanye kwi-scleroderma.
4. Ingxaki kaRaynaud kunye nokudumba kweminwe: Ezi mpawu zenzeka kwi-25% kuphela yabantu abane-lupus.
Ziziphi iindlela zonyango ze-MCTD?
Akukho nyango lwe-MCTD okwangoku. Kodwa kukho unyango oluninzi olusebenzayo olunokukunceda ukulawula iimpawu zakho, uthintele iingxaki, kwaye uphile ubomi obuqhelekileyo. Unyango luxhomekeke kwizinto ezifana nobukhali beempawu zakho kunye namalungu omzimba achaphazelekileyo.
| Uhlobo lweziyobisi | Injongo yokusetyenziswa |
|---|---|
| Ii-Corticosteroids | Umzekelo: I-Prednisone. Yehlisa ukudumba emzimbeni kwaye ithintele ukusebenza kwenkqubo yomzimba yokuzikhusela. |
| Amayeza okulwa nemalariya | Umzekelo, iHydroxychloroquine. Thintela ukudumba kwesikhumba kwaye ulawule iimpawu ezibuthathaka. |
| Izithinteli zemijelo yecalcium | Lawula imeko kaRaynaud. Ezi ziphumza izihlunu ezikwiindonga zemithambo yegazi. |
| Ezinye izinto ezithintela amasosha omzimba | Ukuba amalungu abalulekileyo (njengemiphunga, intliziyo) ayachaphazeleka, lawula inkqubo yomzimba yokuzikhusela. |
| Amayeza okulwa noxinzelelo lwegazi | Lawula uxinzelelo lwegazi oluphezulu lwemiphunga. |
Zeziphi izinto onokuzenza ukuze uzinyamekele?
Ukongeza ekuseleni amayeza, ukwenza utshintsho oluncinci kwindlela ophila ngayo kunokunceda kakhulu ekulawuleni ezi mpawu.
- Ukusetyenziswa kweentlungu ezibuhlungu: Kwiintlungu ezingephi kunye nokudumba, ungathatha amayeza angengo-steroidal anti-inflammatory (NSAIDs) afana ne-Ibuprofen, emva kokubonisana nogqirha wakho .
- Ukuzikhusela kwingqele: Oku kubalulekile ukuthintela isigulo sikaRaynaud. Nxiba iiglavu kunye nee-earflaps xa uphuma kwimozulu ebandayo. Nciphisa ukudibana namanzi abandayo kwaye uqandisise kakhulu.
- Ukuphepha ukutshaya:Ukutshaya kuyayinciphisa imithambo yegazi. Oku kunokwenza imeko kaRaynaud ibe mandundu. Ngoko ke ukuba uyatshaya, kubaluleke kakhulu ukuyeka.
- Nciphisa uxinzelelo: Uxinzelelo lunokubangela ukuba uRaynaud abe nengxaki. Ngoko zama ukuzola ingqondo yakho ngezinto ezifana nokuzilolonga ngokuphefumla kunye nokucamngca. Funa uncedo kumcebisi wezempilo yengqondo ukuba kuyimfuneko.
Udinga nini ukubona ugqirha?
Ukuba unayo nayiphi na kwezi mpawu sizixubushileyo ngaphambili, ingakumbi ukuba ziphazamisana nemisebenzi yakho yemihla ngemihla, licebo elihle ukubona ugqirha. Ukuba unentlungu entsha yemisipha okanye yamalungu, ukudumba kwiminwe yakho, okanye iimpawu zeRaynaud's, kungcono ukubona ugqirha ukuze ahlolwe.
Eminye imibuzo onokuyibuza ugqirha:
* Yintoni unobangela weempawu zam?
* Ngaba ndinesifo esingaphezulu kwesinye sezicwili ezidityanisiweyo?
* Zeziphi iimvavanyo ekufuneka ndizenze?
* Ziziphi iindlela zonyango zale meko?
* Ndingenza ntoni ukuthintela ukudumba kwamalungu omzimba?
Ukuphila nesi sifo kunokuba nzima ngamanye amaxesha. Kodwa ngonyango olufanelekileyo nendlela yokuphila efanelekileyo, ungaphila ubomi obulungileyo. Hlala unxibelelana nogqirha wakho kwaye uthethe ngokukhululekileyo ngezinto ezikuxhalabisayo.
Umyalezo Wokuya Ekhaya
- I-MCTD sisifo esintsonkothileyo nesingaqhelekanga esibangela ukuba iimpawu zezifo ezahlukeneyo zihlangane.
- Ngenxa yokuba iimpawu zivela emva kwenye, kungathatha ixesha ukuxilonga isifo ngokuchanekileyo.
- Nangona esi sifo singenakunyangwa ngokupheleleyo, kunokwenzeka ukulawula iimpawu, ukuthintela iingxaki, nokuphila ubomi obuqhelekileyo.
- Ukuzikhusela kwingqele, ukuphepha ukutshaya, kunye nokulawula uxinzelelo kunceda kakhulu ekunciphiseni iimpawu.
- Soloko uthetha nogqirha wakho ngemeko yakho kwaye uqhubeke novavanyo olufanelekileyo kunye nonyango. Awuwedwa!
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