Ugonyo lweDantrolene: Oko kufuneka ukwazi ngaphambi kokuba ulufumane!

Ngamanye amaxesha kufuneka sinike amayeza akhethekileyo xa kukho imeko engxamisekileyo okanye ngaphambi kotyando, akunjalo? Namhlanje siza kuthetha ngeyeza elisetyenziswa kwiimeko ezinjalo, kodwa elingathethwa kakhulu ngalo. Igama lalo yiDantrolene. Kubaluleke kakhulu ukuba ulazi eli yeza, kuba aliloyeza elinikwa abantu abaninzi.

Yintoni le yeza, Dantrolene?

Ngamafutshane, iDantrolene liyeza eliphumza izihlunu emzimbeni wakho. Ngokukodwa, lisetyenziselwa ukuthintela nokunyanga imeko eyingozi kakhulu nengaqhelekanga ebizwa ngokuba yi -malignant hyperthermia . I-Malignant hyperthermia yimpendulo enzima kwi-anesthetics ethile. Oku kunokubangela ukuba ubushushu bomzimba wakho bunyuke ngokukhawuleza, izihlunu zakho ziqine, nentliziyo yakho ibethe ngokukhawuleza. Ngoko ke, iDantrolene isetyenziselwa ukulawula le mpendulo.

Ngaphandle koku, ngamanye amaxesha oogqirha banokugqiba ekubeni basebenzise eli yeza nakwezinye iimeko zonyango. Ngoko ke, ukuba unemibuzo okanye iinkxalabo malunga neli yeza, kungcono ubuze ugqirha wakho okanye ingcali yezemithi ekunika eli yeza. Baza kukuchazela yonke into.

Ungafumana eli yeza phantsi kwamagama ophawu oluthi `Dantrium`, `Revonto`, okanye `RYANODEX`. Kodwa nokuba ligama lini na, isithako esisebenzayo siyafana, esiyiDantrolene.

Zeziphi izinto ekufuneka uzixelele ugqirha wakho ngaphambi kokuba usebenzise eli yeza?

Ngoku, ngaphambi kokuba unikwe eli yeza leDantrolene, kukho izinto ezimbalwa ekufuneka ziziwe liqela lakho lezonyango - oko kukuthi, oogqirha kunye nabahlengikazi. Kubaluleke kakhulu kukhuseleko lwakho ukubaxelela ngaphandle kokufihla nantoni na, akunjalo? Kuba ngokusekelwe kolu lwazi, kuya kugqitywa ukuba kufanelekile na ukukunika eli yeza okanye akunjalo, okanye zeziphi izilumkiso ekufuneka uzilandele.

Nazi ezinye izinto onokuzithetha ngokuqinisekileyo:

• Ngaba unesifo sentliziyo , oko kukuthi, ngaba uneengxaki ngentliziyo yakho?
• Ngaba unayo nayiphi na ingxaki yesibindi (isifo sesibindi) , oko kukuthi isibindi esibuthathaka, okanye esinye isifo?
• Ngaba unesifo semiphunga , esifana ne-asthma, okanye esinye isifo semiphunga okanye sokuphefumla ?
• Ngaba wakha waba ne-allergy engaqhelekanga (i-allergy) kwi-Dantrolene, naluphi na olunye unyango, ukutya, iidayi zempahla, okanye izithinteli zokutya?
• Ukhulelwe ? Okanye unethemba lokukhulelwa kungekudala?(ukhulelwe okanye uzama ukukhulelwa)
• Ingaba ungumama oncancisayo? (oncancisayo)

Kubaluleke kakhulu ukuzichaza ngokuchanekileyo ezi zinto, kuba kulapho kuphela apho oogqirha baya kukwazi ukugqiba ukuba kufanelekile na ukukunika eli yeza okanye akunjalo, okanye zeziphi izinto ekufuneka uzilumkele ngakumbi.

Ndingakunika njani eli yeza?

Eli yeza ulinikwa njengenaliti emthanjeni . Asilo pilisi okanye isiraphu onokuyithatha ekhaya. Linikwa yingcali yezempilo eqeqeshiweyo, ngokuqhelekileyo esibhedlele okanye eklinikhi . Bayazi kakuhle indlela yokulinika kunye nokuba lingakanani na.

Ukuba unika abantwana abancinci eli yeza, thetha nogqirha wakho wabantwana kwaye ulandele icebiso lakhe. Ngenxa yokuba imizimba yabantwana abancinci yahlukile kweyabantu abadala, kufuneka kuthathwe ingqalelo ekhethekileyo xa ubanika amayeza.

Kuthekani ukuba ndithatha amayeza amaninzi kakhulu? (Umthamo ogqithisileyo)

Njengoko eli yeza linikwa phantsi kweliso likagqirha okanye abasebenzi bezonyango abaqeqeshiweyo, amathuba okuba ufumane amayeza amaninzi kakhulu aphantsi kakhulu. Nangona kunjalo, ukuba ucinga ukuba oku kwenzekile, oko kukuthi, ukuba ukrokrela ukuba ugqithisile , okanye ukuba uzive ungaphili kakuhle, kufuneka wazise abasebenzi bezonyango ngoko nangoko. Baza kuthatha amanyathelo afunekayo.

Kubalulekile: Eli yeza limiselwe wena wedwa . Ungaze wabelane ngalo nabanye abantu. Iyeza elifanelekileyo kunye nomlinganiselo womntu ngamnye wahlukile.

Kuthekani ukuba ndiphoswa lidosi leyeza?

Ekubeni eli yeza linikwa esibhedlele, phantsi kweliso likagqirha, akukho thuba lokuba ungaphoswa yidosi . Abasebenzi bezonyango baza kuyinyamekela. Ngoko ke akufuneki ukhathazeke ngaloo nto.

Ngaba ukuthatha eli yeza kunokubangela iziphumo ebezingalindelekanga kunye namanye amayeza?

Ngoku masithethe ngento ekufuneka uyilumkele. I-Dantrolene inokudibana namanye amayeza owasebenzisayo, oko kuthetha ukuba inokuchaphazelana. Kungoko ke, kubalulekile ukuxelela ugqirha wakho ngawo onke amayeza owasebenzisayo, kungekuphela nje lawo achazwe ngugqirha wakho, kodwa nalawo uwathengayo kwikhemesti, amayeza esintu, iivithamini, njl.

Ngokukodwa, ukuba kukho amayeza e-narcotic okukhwehlela , akucetyiswa kwaphela ukuwasebenzisa kunye neDantrolene.

Kwakhona, la mayeza alandelayo anokusebenzisana neDantrolene. Ngoko ke ukuba uthatha nayiphi na kwezi, qiniseka ukuba uxelela ugqirha wakho :

• Utywala
• Iintlobo zee-antihistamines ze-allergies, ukukhwehlela, kunye nomkhuhlane
• Amanye amayeza anceda ekuxhalabeni nasekulaleni
• Amanye amayeza oxinzelelo lwegazi, isifo sentliziyo, kunye nokubetha kwentliziyo okungaqhelekanga
• Amayeza anjenge-`amitriptyline`, `fluoxetine`, `sertraline`, asetyenziselwa ukunyanga izifo zengqondo ezifana nokudakumba.
• Amayeza anjenge-'phenobarbital' kunye ne-'primidone', asetyenziselwa ukunyanga izifo ezifana nokuxhuzula.
• Iihomoni zabasetyhini, umzekelo, iipilisi zokulawula ukuzalwa, iipatches, iiringi, okanye iinaliti eziqulethe ii-estrogens okanye ii-progestins
• Ii-anesthetics eziqhelekileyo ezifana ne-halothane, i-isoflurane, i-methoxyflurane, kunye ne-propofol, ezisetyenziselwa ukubangela ukuba umntu angabi nangqondo ngexesha lotyando.
• Ii-anesthetics zasekuhlaleni ezifana ne-'lidocaine', i-'pramoxine', ne-'tetracaine', ezithi zingasebenzi kakuhle kwezinye iindawo
• Amanye amayeza asetyenziswa ukuphumza izihlunu ngexesha lotyando
• Amayeza eentlungu ezibangela i-narcotic
• Amayeza akwiqela le-`phenothiazines`, umzekelo `chlorpromazine`, `mesoridazine`, `prochlorperazine`, `thioridazine`

Olu luhlu lusenokungabandakanyi yonke into. Ngoko ke, xelela ugqirha wakho malunga nawo onke amayeza owasebenzisayo, kuquka amayeza aqholiweyo, amayeza angagunyaziswanga ngugqirha, izongezo zokutya, nokuba uyatshaya, usela utywala, okanye usebenzisa iziyobisi ezingekho mthethweni. Ezinye zezi zinto zinokudibana nalo mayeza.

Izinto ekufuneka uzilumkele xa usebenzisa eli yeza

Xa unikwa eli yeza, imeko yakho iya kuhlolwa ngononophelo ngabasebenzi bezonyango . Ngoko ke akukho nto inokubangela uxhalabe ngayo. Nangona kunjalo, kukho izinto ezimbalwa ekufuneka uzazi:

• Eli yeza linokukwenza uzive ulele okanye unesizungu . Ngoko ke, musa ukuqhuba, ukusebenzisa oomatshini abanzima, okanye ukwenza nantoni na efuna ukuphaphama kwengqondo ude wazi ukuba eli yeza likuchaphazela njani. Musa ukuma okanye ukuhlala ngequbuliso, ingakumbi ukuba ungumguli omdala . Ukwenza njalo kunokunciphisa umngcipheko wokuba nesizungu kunye nokuwa.
• Ukusela utywala kunokuphazamisa ukusebenza kakuhle kwale mithi kwaye konyuse iziphumo ebezingalindelekanga. Ngoko ke, phepha utywala ngokupheleleyo xa usebenzisa le mithi.
• Ukuba usebenzisa amanye amayeza akwenza ulale, la mayeza anokukwenza ulale kwaye anokunyusa iziphumo ebezingalindelekanga. Yiyo loo nto besisoloko sisithi xelela ugqirha wakho ngawo onke amayeza owathathayo. Ugqirha wakho uza kukuxelela ukuba mawusele malini. Ungaze uthathe ngaphezu komlinganiselo owunikwe ngugqirha wakho . Ukuba unengxaki yokuphefumla okanye uziva ulele ngendlela engaqhelekanga , fowunela igumbi likaxakeka ngoko nangoko.
• Enye into kukuba eli yeza linokwenza ulusu lwakho lube buthathaka ngakumbi elangeni . Ngoko ke kuphephe ukuchatshazelwa lilanga kangangoko unako. Ukuba kufuneka uphume, nxiba impahla egquma ulusu lwakho, nxiba umnqwazi, kwaye usebenzise i-sunscreen elungileyo . Musa ukusebenzisa izixhobo zokwenziwa zokutshisa ilanga (ezifana nezibane zelanga okanye iibhedi/ii-booth zokutshisa ilanga).

Zithini iziphumo ebezingalindelekanga ezinokubakho zale yeza?

Njengazo zonke iziyobisi, iDantrolene inokubangela iziphumo ebezingalindelekanga kwabanye abantu. Asinguye wonke umntu ozifumanayo. Nangona kunjalo, kulungile ukwazi ezinye izinto.

Iziphumo ebezingalindelekanga ekufuneka uzixelele ugqirha wakho okanye ingcali yezonyango ngokukhawuleza:

Ukuba ufumana naziphi na kwezi mpawu, kufuneka uxelele ugqirha okanye umongikazi ngokukhawuleza:

• Iimpendulo ze-allergy : Ezi ziquka ukurhawuzelela kwesikhumba, ukurhawuzelela, ukurhawuzelela, ukudumba kobuso, imilebe, okanye ulwimi.
• Iingxaki zokuphefumla .
• Iimpawu zesifo sokuwa (ukuxhuzula) , oko kuthetha ukuba ziza ngokukhawuleza.
• Iimpawu kunye neempawu zokulimala kwesibindi : Ezi ziquka umchamo otyheli okanye omdaka omnyama; ukuziva ungaphilanga okanye unomkhuhlane; indle ekhanyayo; ukungabi namdla wokutya; isicaphucaphu; iintlungu kwicala eliphezulu lasekunene lesisu; ukuziva udiniwe ngokungaqhelekanga okanye udiniwe; kunye nokutyheli kwamehlo okanye ulusu (i-jaundice).
• Ubuthathaka okanye ukudinwa ngokungaqhelekanga .

Iziphumo ebezingalindelekanga oqhele ukuxelela ugqirha wakho ngazo, kodwa ekufuneka zixelwe ukuba ziyaqhubeka okanye ziyakukhathaza:

Ezi zifo azibalulekanga kangako kwaye ziya kuphela emva kweentsuku ezimbalwa. Kodwa ukuba ziyaqhubeka, xelela ugqirha wakho ukuba ziyakukhathaza:

• Ukuqhinwa kwesisu .
• Isiyezi .
• Isicaphucaphu, ukuhlanza .
• Intlungu, ukubomvu, okanye ukurhawuzelelwa kwindawo apho kufakwe khona inaliti .
• Ingxaki yokuthetha , njengokuthetha amagama angacacanga.

Olu luhlu lusenokungazibandakanyi zonke iziphumo ebezingalindelekanga. Ngoko ke, ukuba ufumana nantoni na engaqhelekanga, qhagamshelana nogqirha wakho. E-United States, i-FDA (i-Food and Drug Administration) inomnxeba okhethekileyo (1-800-FDA-1088) apho unokuxela khona ezo ziphumo bezingalindelekanga. Kwilizwe lethu, ugqirha wakho ngoyena mcebisi ubalaseleyo.

Uligcina njani eli yeza?

Ekubeni eli yeza linikwa wena esibhedlele okanye ekliniki, akufuneki ulithathe uye nalo ekhaya okanye uligcine ekhaya . Ligcinwa kwikhemesti yesibhedlele kubushushu obufanelekileyo, njengoko kufuneka. Ngoko ke akufuneki ukhathazeke ngalo.

Okokugqibela, ezona zinto zibalulekileyo ekufuneka uzikhumbule

Kulungile, ngoko ke sithethe kakhulu ngale chiza libizwa ngokuba yiDantrolene, akunjalo? Khumbula, le yi-muscle relaxant ebalulekileyo esetyenziswa kwiimeko ezikhethekileyo, ingakumbi kwiimeko ezingxamisekileyo ezifana ne-malignant hyperthermia.

Eyona nto ibalulekileyo kukuxelela ugqirha wakho ngeemeko zempilo yakho, amanye amayeza owasebenzisayo, kunye nazo naziphi na izinto ezibangela ukuba ungabi namdla kwizinto ezithile. Oku kungenxa yokhuseleko lwakho.

Qaphela ukuba eli yeza linokukwenza uzive ulele kwaye unesiyezi. Kwakhona, ungalibali ukulumka xa uphuma elangeni.

Ukuba ufumana naziphi na iimpawu ezingaqhelekanga okanye iziphumo ebezingalindelekanga, nokuba zincinci, ungathandabuzi ukuxelela ugqirha wakho. Ukhuseleko lwakho yeyona nto iphambili kubo. Siyathemba ukuba olu lwazi luza kukunceda. Ukuba uneminye imibuzo, ungathandabuzi ukubuza ugqirha wakho okanye ingcali yezonyango, kulungile?

I- Dantrolene, isiphumzi semisipha, i-malignant hyperthermia, iziphumo ebezingalindelekanga, amayeza, isitofu, impilo, unyango